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The map label for this gene is ycjU [C]

Identifier: 116493941

GI number: 116493941

Start: 375738

End: 376415

Strand: Direct

Name: ycjU [C]

Synonym: LSEI_0375

Alternate gene names: 116493941

Gene position: 375738-376415 (Clockwise)

Preceding gene: 116493940

Following gene: 116493942

Centisome position: 12.98

GC content: 41.74

Gene sequence:

>678_bases
ATGACAGGGTTAATCTTTGATTTTAATGGGACACTCTTCGCAGATGCTGACAAGCAGGAGATTGCTTGGCGTCAGTTCGC
TCAAAACTATGCGAAAAAAGAACTATCAGACCAGGAATTTGATGATCACGTTCACGGACAAAATGCTGAACTGACGCTTA
ACTATTTGTTTGAGCGGGTACTGAGTCAAAAAGAAATTGATGAATTTAGTGAGCAGAAGGAAGTTATCTACCGTGAATTA
TGCGTTTCAGATGCTAAAAATTTTCACTTGTTGAGGGGTGCTCCAGCGTTTCTTGATGAGTTGCAGGCTCGTCATGTGCC
GATGACAATTGCAACGGCATCAGCGCAAAAGAACGTTGAATTCTTCTTTGATGCCTTTAACTTGACGAAGTGGTTCAATA
TTGAGGATGTAGTATTTGATGATGGCACAATGAAGAGCAAACCGGATCCCGACCCATTTCTAAAAGCGGCGGCAAAATTA
CACTTGCCTTCTTCAAACACAATTATCTTTGAAGATTCGCCTTCTGGATTTGCTGCCGCTGAGGCAGCTGGCGCTAAGAG
AATTGTGGGTATTGTAACTGGTAATCGTTCGACGCTTGAAGCAGATTCGCGCTTAGATTTGATTCTGGACGATTATCAAA
AGTTATCAGGTCGAATGATTGATCAACTACTTTATTAA

Upstream 100 bases:

>100_bases
AGGGCCAACAAATTGGTGAACTGATATACGTTTAAAGAATCTGAATCATAACTTTTACCGACGCGATGATAGTCACATGG
CCAATATCTGGGGGATTCTA

Downstream 100 bases:

>100_bases
CATGAAAATTTTGTAGCTCAAACGCTGATCTGCTTGTATTTCTTACAGGTGAATTGGCGTTTTTGAAGTGGTGAATAAAA
AACTGGATTGACTATATAAT

Product: HAD family sugar phosphatase

Products: beta-D-glucose 6-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MTGLIFDFNGTLFADADKQEIAWRQFAQNYAKKELSDQEFDDHVHGQNAELTLNYLFERVLSQKEIDEFSEQKEVIYREL
CVSDAKNFHLLRGAPAFLDELQARHVPMTIATASAQKNVEFFFDAFNLTKWFNIEDVVFDDGTMKSKPDPDPFLKAAAKL
HLPSSNTIIFEDSPSGFAAAEAAGAKRIVGIVTGNRSTLEADSRLDLILDDYQKLSGRMIDQLLY

Sequences:

>Translated_225_residues
MTGLIFDFNGTLFADADKQEIAWRQFAQNYAKKELSDQEFDDHVHGQNAELTLNYLFERVLSQKEIDEFSEQKEVIYREL
CVSDAKNFHLLRGAPAFLDELQARHVPMTIATASAQKNVEFFFDAFNLTKWFNIEDVVFDDGTMKSKPDPDPFLKAAAKL
HLPSSNTIIFEDSPSGFAAAEAAGAKRIVGIVTGNRSTLEADSRLDLILDDYQKLSGRMIDQLLY
>Mature_224_residues
TGLIFDFNGTLFADADKQEIAWRQFAQNYAKKELSDQEFDDHVHGQNAELTLNYLFERVLSQKEIDEFSEQKEVIYRELC
VSDAKNFHLLRGAPAFLDELQARHVPMTIATASAQKNVEFFFDAFNLTKWFNIEDVVFDDGTMKSKPDPDPFLKAAAKLH
LPSSNTIIFEDSPSGFAAAEAAGAKRIVGIVTGNRSTLEADSRLDLILDDYQKLSGRMIDQLLY

Specific function: Displays high phosphatase activity toward erythrose 4- phosphate, fructose 6-phosphate, 2-deoxyglucose 6-phosphate, and mannose 6-phosphate. May have a role in the intracellular metabolism of many phosphorylated carbohydrates [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 5.4.2.6

Molecular weight: Translated: 25454; Mature: 25323

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGLIFDFNGTLFADADKQEIAWRQFAQNYAKKELSDQEFDDHVHGQNAELTLNYLFERV
CCCEEEECCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEHHHHHHHH
LSQKEIDEFSEQKEVIYRELCVSDAKNFHLLRGAPAFLDELQARHVPMTIATASAQKNVE
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHCCCCEEEEECCCCCCCE
FFFDAFNLTKWFNIEDVVFDDGTMKSKPDPDPFLKAAAKLHLPSSNTIIFEDSPSGFAAA
EEEEHHCCCEECCCCEEEECCCCCCCCCCCCHHHHHHHHEECCCCCEEEEECCCCCCHHH
EAAGAKRIVGIVTGNRSTLEADSRLDLILDDYQKLSGRMIDQLLY
HHCCCCEEEEEEECCCCEECCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TGLIFDFNGTLFADADKQEIAWRQFAQNYAKKELSDQEFDDHVHGQNAELTLNYLFERV
CCEEEECCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEHHHHHHHH
LSQKEIDEFSEQKEVIYRELCVSDAKNFHLLRGAPAFLDELQARHVPMTIATASAQKNVE
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHCCCCEEEEECCCCCCCE
FFFDAFNLTKWFNIEDVVFDDGTMKSKPDPDPFLKAAAKLHLPSSNTIIFEDSPSGFAAA
EEEEHHCCCEECCCCEEEECCCCCCCCCCCCHHHHHHHHEECCCCCEEEEECCCCCCHHH
EAAGAKRIVGIVTGNRSTLEADSRLDLILDDYQKLSGRMIDQLLY
HHCCCCEEEEEEECCCCEECCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: beta-D-glucose 1-phosphate

Specific reaction: beta-D-glucose 1-phosphate = beta-D-glucose 6-phosphate

General reaction: Group transfer (intramolecular phosphate group isomerization [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]