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The map label for this gene is rbsK [H]

Identifier: 116493880

GI number: 116493880

Start: 312693

End: 313622

Strand: Direct

Name: rbsK [H]

Synonym: LSEI_0312

Alternate gene names: 116493880

Gene position: 312693-313622 (Clockwise)

Preceding gene: 116493878

Following gene: 116493883

Centisome position: 10.8

GC content: 52.9

Gene sequence:

>930_bases
ATGCCTAATCATGTTGTTGTCATCGGCAGTATCAATGTGGATAGCATCTTGCACATTCAACGGTTGCCACAACCGGGAGA
AACGATCAAAATGGACACCTTTTCACAAGCGGCTGGCGGTAAAGGTGCGAATCAAGCAGTTGCGGCTGCGCGTTCGGGGG
CCAAAACCAGTTTTATTGGCCGAGTTGGTGACGATGCCAACGCTGCCTTCATGCGCGGTGAACTTGTCAAGAACCAAATC
GACACCCAATATGTGGCGACAACGGTTGGCACGCAAACCGGTCAGGCTTACATTTTGCTGCAAGCCTCTGGCCAAAATTC
CATTATCATCCAGCATGGCGCTAATTTTGAGGTGACACCAGCAGATGTGCAACGAGCAGCCGACTTGATTCAGTCTGCCG
ACTTTGTGGTCGCGGAATTTGAAACACCGGTGGATGCGACGGCAGAGGCCTTCAAAATTGCCAAAGCCGCTGGGAAGATG
ACCATCTTAAACCCAGCGCCAGCACAGAAGGATTTGCCAGCAGCCTTGCTGAAAAATGTGGATCTCATCGCACCGAACGA
AACCGAAAGCGAGCTGATCACCGGCATTCCGGTGGTAGATGAAGACAGCATGCGGGCTTCGGCAGCTTATTATCATGAAT
TAGGCATTCGCGGGGTGATCATCACTTTAGGATCAAAAGGCTCCTTCATCTCGCTGGATGGCGAAGCAACCATCGTGCCA
GCCTTTAAAGTCAAGGCTGTCGACACCACCGCCGCGGGCGACACGTTCATTGGTGCCTTGGCAAGCGTCTTGCAGACAGA
CCTCAAGAACATTGTCACCGCTGCGACCTACGCCAGCATGGCAAGTTCTTTCACGGTTCAGAAACTTGGCGCCTTCCCGT
CCATTCCGATGGGGGATGAGGTGCGGGCGGCGTTAGCGAAAATCAAGTGA

Upstream 100 bases:

>100_bases
TTAAGTTAGAAAAGGGGGCCGACTTATCGGCCCTTTTTAATTAGAGCGTGAGCAGGCCGTTTTCTGGACGAGCGAGCGCG
TTTCAATTGGAGGAAATCTT

Downstream 100 bases:

>100_bases
GGGTATAACGAGTAAATCACTGGAGCAAAACCTACCTTAATCAAAACAAGAAAGCTGGCAGTCGTGCTTACCTCACACGA
TTGCCAGCTTTCTTGTTTTA

Product: ribokinase family sugar kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MPNHVVVIGSINVDSILHIQRLPQPGETIKMDTFSQAAGGKGANQAVAAARSGAKTSFIGRVGDDANAAFMRGELVKNQI
DTQYVATTVGTQTGQAYILLQASGQNSIIIQHGANFEVTPADVQRAADLIQSADFVVAEFETPVDATAEAFKIAKAAGKM
TILNPAPAQKDLPAALLKNVDLIAPNETESELITGIPVVDEDSMRASAAYYHELGIRGVIITLGSKGSFISLDGEATIVP
AFKVKAVDTTAAGDTFIGALASVLQTDLKNIVTAATYASMASSFTVQKLGAFPSIPMGDEVRAALAKIK

Sequences:

>Translated_309_residues
MPNHVVVIGSINVDSILHIQRLPQPGETIKMDTFSQAAGGKGANQAVAAARSGAKTSFIGRVGDDANAAFMRGELVKNQI
DTQYVATTVGTQTGQAYILLQASGQNSIIIQHGANFEVTPADVQRAADLIQSADFVVAEFETPVDATAEAFKIAKAAGKM
TILNPAPAQKDLPAALLKNVDLIAPNETESELITGIPVVDEDSMRASAAYYHELGIRGVIITLGSKGSFISLDGEATIVP
AFKVKAVDTTAAGDTFIGALASVLQTDLKNIVTAATYASMASSFTVQKLGAFPSIPMGDEVRAALAKIK
>Mature_308_residues
PNHVVVIGSINVDSILHIQRLPQPGETIKMDTFSQAAGGKGANQAVAAARSGAKTSFIGRVGDDANAAFMRGELVKNQID
TQYVATTVGTQTGQAYILLQASGQNSIIIQHGANFEVTPADVQRAADLIQSADFVVAEFETPVDATAEAFKIAKAAGKMT
ILNPAPAQKDLPAALLKNVDLIAPNETESELITGIPVVDEDSMRASAAYYHELGIRGVIITLGSKGSFISLDGEATIVPA
FKVKAVDTTAAGDTFIGALASVLQTDLKNIVTAATYASMASSFTVQKLGAFPSIPMGDEVRAALAKIK

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=258, Percent_Identity=39.1472868217054, Blast_Score=161, Evalue=7e-40,
Organism=Escherichia coli, GI1790193, Length=303, Percent_Identity=44.2244224422442, Blast_Score=227, Evalue=9e-61,
Organism=Escherichia coli, GI87082343, Length=303, Percent_Identity=30.3630363036304, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87081971, Length=281, Percent_Identity=28.8256227758007, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788491, Length=270, Percent_Identity=24.0740740740741, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=302, Percent_Identity=36.7549668874172, Blast_Score=161, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6319884, Length=331, Percent_Identity=32.3262839879154, Blast_Score=128, Evalue=1e-30,
Organism=Drosophila melanogaster, GI20128807, Length=306, Percent_Identity=36.2745098039216, Blast_Score=146, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24583886, Length=312, Percent_Identity=30.1282051282051, Blast_Score=123, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 32201; Mature: 32070

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNHVVVIGSINVDSILHIQRLPQPGETIKMDTFSQAAGGKGANQAVAAARSGAKTSFIG
CCCCEEEEECCCHHHHHHHHHCCCCCCEEEECCCHHHCCCCCCHHHHHHHHCCCCEEEEE
RVGDDANAAFMRGELVKNQIDTQYVATTVGTQTGQAYILLQASGQNSIIIQHGANFEVTP
CCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEECCCCCEEEEECCCEEECH
ADVQRAADLIQSADFVVAEFETPVDATAEAFKIAKAAGKMTILNPAPAQKDLPAALLKNV
HHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHCCC
DLIAPNETESELITGIPVVDEDSMRASAAYYHELGIRGVIITLGSKGSFISLDGEATIVP
EEECCCCCHHHHEECCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCEEEECCCEEEEE
AFKVKAVDTTAAGDTFIGALASVLQTDLKNIVTAATYASMASSFTVQKLGAFPSIPMGDE
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
VRAALAKIK
HHHHHHHCC
>Mature Secondary Structure 
PNHVVVIGSINVDSILHIQRLPQPGETIKMDTFSQAAGGKGANQAVAAARSGAKTSFIG
CCCEEEEECCCHHHHHHHHHCCCCCCEEEECCCHHHCCCCCCHHHHHHHHCCCCEEEEE
RVGDDANAAFMRGELVKNQIDTQYVATTVGTQTGQAYILLQASGQNSIIIQHGANFEVTP
CCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEECCCCCEEEEECCCEEECH
ADVQRAADLIQSADFVVAEFETPVDATAEAFKIAKAAGKMTILNPAPAQKDLPAALLKNV
HHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHCCC
DLIAPNETESELITGIPVVDEDSMRASAAYYHELGIRGVIITLGSKGSFISLDGEATIVP
EEECCCCCHHHHEECCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCEEEECCCEEEEE
AFKVKAVDTTAAGDTFIGALASVLQTDLKNIVTAATYASMASSFTVQKLGAFPSIPMGDE
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
VRAALAKIK
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]