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The map label for this gene is nisX1 [H]

Identifier: 116493841

GI number: 116493841

Start: 273361

End: 274176

Strand: Direct

Name: nisX1 [H]

Synonym: LSEI_0273

Alternate gene names: 116493841

Gene position: 273361-274176 (Clockwise)

Preceding gene: 116493840

Following gene: 116493842

Centisome position: 9.44

GC content: 44.0

Gene sequence:

>816_bases
TTGTTAGACGTATCAACGAGTGGTTATTATGCTTGGCGGAGAGCTTTGCCAAAGCGAAACGCCAAAGAAAGGCAATATCG
TCAACGAATCAAACACTTTTTTGATCAAGGACAGGGCACTTACGGGCCCAAACGCATCTGCGGTTTATTGCGTAAAAATG
GTAATAAAGCTTCCTATCACCGAGTTGCCCGTCTGATGGCTGATGGCGGTCTGTATTCAACGCTACGTTGTCGTCATCCG
AAGAGTTTGACCGATAGCCGCCTTGCTCGTCAAGGTGATTATCCCAATCTAGTGAAACACCAATCTTTTAAGCCGTTTGA
AGCCTTATCAAGTGACATTACACAGACGACAACATCAGAAGGAAAAGCTTACATTTGCCAAATAAGGGATTTGAACAGCA
ACCTAGTGTTAGCTCATCAAATATCCAATCATATGGACACGGATTTAGTCTTAGCGACACTTAAACAAGCCCACCAAAGG
TGGGCTTTGCCAGAAACGTGTATTTTTCATAGTGACCGTGGTAGCCAATACACGGCCAAAGCAGTGACAAAGTTGGTCAA
CCAATATCATTGGCAACGTAGCTTCTCAGCATTGGGAAAACCGGGTGATAACGCTTGGAGCGAAAGCTTCTTTGCCATCA
TGAAGAAAGAGCTCATTTATCAGATACAATTTAAAGATATCAATGATCTGAGAGCGCAAGTCTTCGCTTACATCGAGACC
TTTTACAACCGCGTAAGGGTACAAGCACGCTTAGACTATCTTGCACCAGTAGCATGGCTTTCCTTGTATGACCAAGCTTC
ACAAAAAGTCGCTTAG

Upstream 100 bases:

>100_bases
AAGCCGCTGCCTACTTTGCCAGTCTCCAGAAGTAACCCCCAGCGATAAGTATGCTTTTATGTTGAGGGAAACCTCTGTTT
CTGTGGTAAGGTGGGCGCAT

Downstream 100 bases:

>100_bases
CAAACTGTCCGAAAAAGTGTTGACTTCCCTTATCCACTTGAGAAATAAAACGGCCCACGTCATTTTGAAAAATGGAGGCT
TTTATGAATCTGAAGGACCA

Product: transposase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MLDVSTSGYYAWRRALPKRNAKERQYRQRIKHFFDQGQGTYGPKRICGLLRKNGNKASYHRVARLMADGGLYSTLRCRHP
KSLTDSRLARQGDYPNLVKHQSFKPFEALSSDITQTTTSEGKAYICQIRDLNSNLVLAHQISNHMDTDLVLATLKQAHQR
WALPETCIFHSDRGSQYTAKAVTKLVNQYHWQRSFSALGKPGDNAWSESFFAIMKKELIYQIQFKDINDLRAQVFAYIET
FYNRVRVQARLDYLAPVAWLSLYDQASQKVA

Sequences:

>Translated_271_residues
MLDVSTSGYYAWRRALPKRNAKERQYRQRIKHFFDQGQGTYGPKRICGLLRKNGNKASYHRVARLMADGGLYSTLRCRHP
KSLTDSRLARQGDYPNLVKHQSFKPFEALSSDITQTTTSEGKAYICQIRDLNSNLVLAHQISNHMDTDLVLATLKQAHQR
WALPETCIFHSDRGSQYTAKAVTKLVNQYHWQRSFSALGKPGDNAWSESFFAIMKKELIYQIQFKDINDLRAQVFAYIET
FYNRVRVQARLDYLAPVAWLSLYDQASQKVA
>Mature_271_residues
MLDVSTSGYYAWRRALPKRNAKERQYRQRIKHFFDQGQGTYGPKRICGLLRKNGNKASYHRVARLMADGGLYSTLRCRHP
KSLTDSRLARQGDYPNLVKHQSFKPFEALSSDITQTTTSEGKAYICQIRDLNSNLVLAHQISNHMDTDLVLATLKQAHQR
WALPETCIFHSDRGSQYTAKAVTKLVNQYHWQRSFSALGKPGDNAWSESFFAIMKKELIYQIQFKDINDLRAQVFAYIET
FYNRVRVQARLDYLAPVAWLSLYDQASQKVA

Specific function: Involved in the transposition of the insertion sequence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=204, Percent_Identity=27.4509803921569, Blast_Score=83, Evalue=3e-16,
Organism=Escherichia coli, GI1789981, Length=259, Percent_Identity=27.027027027027, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788405, Length=266, Percent_Identity=30.4511278195489, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1787263, Length=266, Percent_Identity=30.4511278195489, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1786753, Length=266, Percent_Identity=30.4511278195489, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1786570, Length=266, Percent_Identity=30.4511278195489, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1786490, Length=266, Percent_Identity=30.4511278195489, Blast_Score=92, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 31321; Mature: 31321

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDVSTSGYYAWRRALPKRNAKERQYRQRIKHFFDQGQGTYGPKRICGLLRKNGNKASYH
CCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHH
RVARLMADGGLYSTLRCRHPKSLTDSRLARQGDYPNLVKHQSFKPFEALSSDITQTTTSE
HHHHHHHCCCCHHHHCCCCCCCCHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHCCC
GKAYICQIRDLNSNLVLAHQISNHMDTDLVLATLKQAHQRWALPETCIFHSDRGSQYTAK
CCEEEEEEEECCCCEEEEEHHHCCCCHHHHHHHHHHHHHHCCCCHHHEEECCCCCCHHHH
AVTKLVNQYHWQRSFSALGKPGDNAWSESFFAIMKKELIYQIQFKDINDLRAQVFAYIET
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHH
FYNRVRVQARLDYLAPVAWLSLYDQASQKVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLDVSTSGYYAWRRALPKRNAKERQYRQRIKHFFDQGQGTYGPKRICGLLRKNGNKASYH
CCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHH
RVARLMADGGLYSTLRCRHPKSLTDSRLARQGDYPNLVKHQSFKPFEALSSDITQTTTSE
HHHHHHHCCCCHHHHCCCCCCCCHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHCCC
GKAYICQIRDLNSNLVLAHQISNHMDTDLVLATLKQAHQRWALPETCIFHSDRGSQYTAK
CCEEEEEEEECCCCEEEEEHHHCCCCHHHHHHHHHHHHHHCCCCHHHEEECCCCCCHHHH
AVTKLVNQYHWQRSFSALGKPGDNAWSESFFAIMKKELIYQIQFKDINDLRAQVFAYIET
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHH
FYNRVRVQARLDYLAPVAWLSLYDQASQKVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1482189; 11337471; 1482192 [H]