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The map label for this gene is iap [H]

Identifier: 116493457

GI number: 116493457

Start: 1706136

End: 1706645

Strand: Direct

Name: iap [H]

Synonym: PEPE_1729

Alternate gene names: 116493457

Gene position: 1706136-1706645 (Clockwise)

Preceding gene: 116493453

Following gene: 116493460

Centisome position: 93.11

GC content: 41.18

Gene sequence:

>510_bases
ATGCATACCAAATTACTTCTATCCAGTATGACCGTTTTAATGGGATTAACTTTCAGCATTCATAGTGTTTCAGCCCATGG
TTTTTCACCACAAGTAGCTCCACTTTCAGATTCACCTTCAGCTGAAGTTCACCACCCATCGTCCCAGCCCTCTTCTGCTT
CATCTAATTCTTTTACTGCAATTCAGACGGTATTATCACAACATATGGGTCAGCCTTACCTTTGGGGAGCTACTGGACCC
ACAGCCTTCGATTGTTCGGGCTTAACTCAATACACCTTTAAAAAAGCTCTAAATCTTAATTTAAATCGTACCGCCGAACA
ACAATTTAACCAATTTCGCCATGTTAGCCATGATCAAGTCCGTCCTGGAGATTTAATTTTCTTTTCTTATAATCATGGGC
AATCCATTGATCACGTTGGCATCATTGTTGAAGGTCAAAACATGATGGTAGATGCTCAAAATCGGGGCGTTATTCGTGAA
TGTTATCTAGTTCCTTGGTGGCGAGGGTAA

Upstream 100 bases:

>100_bases
CTCTATTTCTTAACTTTTTCATTATCCCATAAAACCTTTTCTAGAATTTCTATTTTAAAAACGTATTTATGGTATGTAAT
CAAAATCTAGGAGGATTTTT

Downstream 100 bases:

>100_bases
TTGAATAAATAAAAAAAAGAATTCCAGCTGGAATTCTTTTTTATTAACCAAAATGACGCTTCCACCAACCTTGTTTAGGT
TGATCAAGAATTTTTTGGTT

Product: cell wall-associated hydrolase

Products: NA

Alternate protein names: Invasion-associated protein [H]

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MHTKLLLSSMTVLMGLTFSIHSVSAHGFSPQVAPLSDSPSAEVHHPSSQPSSASSNSFTAIQTVLSQHMGQPYLWGATGP
TAFDCSGLTQYTFKKALNLNLNRTAEQQFNQFRHVSHDQVRPGDLIFFSYNHGQSIDHVGIIVEGQNMMVDAQNRGVIRE
CYLVPWWRG

Sequences:

>Translated_169_residues
MHTKLLLSSMTVLMGLTFSIHSVSAHGFSPQVAPLSDSPSAEVHHPSSQPSSASSNSFTAIQTVLSQHMGQPYLWGATGP
TAFDCSGLTQYTFKKALNLNLNRTAEQQFNQFRHVSHDQVRPGDLIFFSYNHGQSIDHVGIIVEGQNMMVDAQNRGVIRE
CYLVPWWRG
>Mature_169_residues
MHTKLLLSSMTVLMGLTFSIHSVSAHGFSPQVAPLSDSPSAEVHHPSSQPSSASSNSFTAIQTVLSQHMGQPYLWGATGP
TAFDCSGLTQYTFKKALNLNLNRTAEQQFNQFRHVSHDQVRPGDLIFFSYNHGQSIDHVGIIVEGQNMMVDAQNRGVIRE
CYLVPWWRG

Specific function: This major extracellular protein may be involved in the invasion of non-professional phagocytic cells by Listeria [H]

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1786421, Length=108, Percent_Identity=37.037037037037, Blast_Score=71, Evalue=3e-14,
Organism=Escherichia coli, GI1788001, Length=128, Percent_Identity=30.46875, Blast_Score=67, Evalue=4e-13,
Organism=Escherichia coli, GI1787944, Length=82, Percent_Identity=36.5853658536585, Blast_Score=67, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064
- InterPro:   IPR018392
- InterPro:   IPR002482
- InterPro:   IPR003646
- InterPro:   IPR013247 [H]

Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60; PF08239 SH3_3 [H]

EC number: NA

Molecular weight: Translated: 18701; Mature: 18701

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTKLLLSSMTVLMGLTFSIHSVSAHGFSPQVAPLSDSPSAEVHHPSSQPSSASSNSFTA
CCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCHHH
IQTVLSQHMGQPYLWGATGPTAFDCSGLTQYTFKKALNLNLNRTAEQQFNQFRHVSHDQV
HHHHHHHHCCCCEEEECCCCCEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCC
RPGDLIFFSYNHGQSIDHVGIIVEGQNMMVDAQNRGVIRECYLVPWWRG
CCCCEEEEEECCCCCCCEEEEEEECCEEEEECCCCCEEEEEEEECCCCC
>Mature Secondary Structure
MHTKLLLSSMTVLMGLTFSIHSVSAHGFSPQVAPLSDSPSAEVHHPSSQPSSASSNSFTA
CCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCHHH
IQTVLSQHMGQPYLWGATGPTAFDCSGLTQYTFKKALNLNLNRTAEQQFNQFRHVSHDQV
HHHHHHHHCCCCEEEECCCCCEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCC
RPGDLIFFSYNHGQSIDHVGIIVEGQNMMVDAQNRGVIRECYLVPWWRG
CCCCEEEEEECCCCCCCEEEEEEECCEEEEECCCCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2111287; 1459966; 11679669 [H]