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The map label for this gene is nixA [H]

Identifier: 116493424

GI number: 116493424

Start: 1671286

End: 1672293

Strand: Direct

Name: nixA [H]

Synonym: PEPE_1696

Alternate gene names: 116493424

Gene position: 1671286-1672293 (Clockwise)

Preceding gene: 116493423

Following gene: 116493433

Centisome position: 91.21

GC content: 39.19

Gene sequence:

>1008_bases
ATGAAGAAGAAATTATTTTATGGAGCACTTCCGTATTACACAGCTAGCTTGGCTATCCATATTTTGGGCATTATCTTACT
GTTAGTTGCTGCCCAAAAACATCCTAGTTTTCTGGGGTTAGGTGTGCTAGCTTACACCCTGGGGCTACGTCATGCCTTTG
ATGCCGATCATATAGCCGCGATAGATAATACCGTTCGTTTATTAATCCACCAAAAGAAGCAACCTTATGGAGTTGGATTT
TTCTTCTCATTAGGCCACTCTACTGTTGTATTTCTAATGGCTTTAGTCGTTAGTATTTCTGCTAAATGGGCCCAAGTTAA
GCTACCCATTCTAGAAGCCATTGGTGGAAAAATCGGTACGATTGTATCCGGTAGTTTTCTTATTTTAATCGCCTTTTTTA
ATTTAATGGTCTTAATCAAACTTTATAAATCACTGAGATTAGTAAAATCCGGTCTTGATGAACAAGAATTAAACGATTTA
CTGCTATCTAGAGGTTTTATTGCTAACTTAGTTTCTCCTTTATTCAAGAAAATCGTTCATGCTTGGCAGATGTATCCAAT
TGGATTCCTATTTGGTTTAGGCTTTGACACCGCCACTGAGATTGCCTTGATTGCGCTATCGGCAACGGCTGCTCAATCAA
ACGTATCGGTAGCCGGAATCATCGCCCTCCCAGTTTTATTTGCCGCTGGAATGAACGTGATGGATACAACCGATTCCGTG
ATGATGTCAGGTGCCTACACATGGGCATTTGATACTCCTAAGCGTAAGGCTTACTACAATTTAACCGTTACTTTTGTTTC
AGTCATTGCAGCTTTCTTAATTGGTTTAGTCGAGTTAGGCAACGTCTTTGCTGACTTTACCCACGTTAATTCTAGTTTCA
TCACATGGATTCAATCGATTGATTTAAATTGGCTGGGCTATGGTCTGGTAATTGGGTTCATATTAATGTGGAGTTTGGCT
TATCTTTTTTGGAAATTATTTATTCAGAAAAACGAACAGCACGCATAA

Upstream 100 bases:

>100_bases
AAGAACAACACGTAATTGATATCAAGAATCAGAAAATTTTTATTTATGATGAAAACTATTTACGTGAATTTACGATTTAA
AAGTTAGGAGAAATATCGTT

Downstream 100 bases:

>100_bases
AAAGAAACAGCATTTCAACTGTGAAATGCTGTTTCTTTTTGGACTAATTCGAGTGAATACAAAAAACACGTTCCTAATAT
CAGAACGTGTTACAAACTTT

Product: high-affinity nickel permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MKKKLFYGALPYYTASLAIHILGIILLLVAAQKHPSFLGLGVLAYTLGLRHAFDADHIAAIDNTVRLLIHQKKQPYGVGF
FFSLGHSTVVFLMALVVSISAKWAQVKLPILEAIGGKIGTIVSGSFLILIAFFNLMVLIKLYKSLRLVKSGLDEQELNDL
LLSRGFIANLVSPLFKKIVHAWQMYPIGFLFGLGFDTATEIALIALSATAAQSNVSVAGIIALPVLFAAGMNVMDTTDSV
MMSGAYTWAFDTPKRKAYYNLTVTFVSVIAAFLIGLVELGNVFADFTHVNSSFITWIQSIDLNWLGYGLVIGFILMWSLA
YLFWKLFIQKNEQHA

Sequences:

>Translated_335_residues
MKKKLFYGALPYYTASLAIHILGIILLLVAAQKHPSFLGLGVLAYTLGLRHAFDADHIAAIDNTVRLLIHQKKQPYGVGF
FFSLGHSTVVFLMALVVSISAKWAQVKLPILEAIGGKIGTIVSGSFLILIAFFNLMVLIKLYKSLRLVKSGLDEQELNDL
LLSRGFIANLVSPLFKKIVHAWQMYPIGFLFGLGFDTATEIALIALSATAAQSNVSVAGIIALPVLFAAGMNVMDTTDSV
MMSGAYTWAFDTPKRKAYYNLTVTFVSVIAAFLIGLVELGNVFADFTHVNSSFITWIQSIDLNWLGYGLVIGFILMWSLA
YLFWKLFIQKNEQHA
>Mature_335_residues
MKKKLFYGALPYYTASLAIHILGIILLLVAAQKHPSFLGLGVLAYTLGLRHAFDADHIAAIDNTVRLLIHQKKQPYGVGF
FFSLGHSTVVFLMALVVSISAKWAQVKLPILEAIGGKIGTIVSGSFLILIAFFNLMVLIKLYKSLRLVKSGLDEQELNDL
LLSRGFIANLVSPLFKKIVHAWQMYPIGFLFGLGFDTATEIALIALSATAAQSNVSVAGIIALPVLFAAGMNVMDTTDSV
MMSGAYTWAFDTPKRKAYYNLTVTFVSVIAAFLIGLVELGNVFADFTHVNSSFITWIQSIDLNWLGYGLVIGFILMWSLA
YLFWKLFIQKNEQHA

Specific function: High-affinity nickel intake protein. Imports nickel ions in an energy-dependent fashion. Necessary for the expression of catalytically active urease [H]

COG id: COG3376

COG function: function code P; High-affinity nickel permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NiCoT transporter (TC 2.A.52) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004688
- InterPro:   IPR011541 [H]

Pfam domain/function: PF03824 NicO [H]

EC number: NA

Molecular weight: Translated: 36894; Mature: 36894

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKLFYGALPYYTASLAIHILGIILLLVAAQKHPSFLGLGVLAYTLGLRHAFDADHIAA
CCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHH
IDNTVRLLIHQKKQPYGVGFFFSLGHSTVVFLMALVVSISAKWAQVKLPILEAIGGKIGT
HHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCHHHEEHHHHHHCCCCHHH
IVSGSFLILIAFFNLMVLIKLYKSLRLVKSGLDEQELNDLLLSRGFIANLVSPLFKKIVH
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHH
AWQMYPIGFLFGLGFDTATEIALIALSATAAQSNVSVAGIIALPVLFAAGMNVMDTTDSV
HHHHHHHHHHHHCCCCHHHHHHHHHEEHHHHHCCCCHHHHHHHHHHHHCCCCHHCCCHHH
MMSGAYTWAFDTPKRKAYYNLTVTFVSVIAAFLIGLVELGNVFADFTHVNSSFITWIQSI
HHCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHC
DLNWLGYGLVIGFILMWSLAYLFWKLFIQKNEQHA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKKKLFYGALPYYTASLAIHILGIILLLVAAQKHPSFLGLGVLAYTLGLRHAFDADHIAA
CCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHH
IDNTVRLLIHQKKQPYGVGFFFSLGHSTVVFLMALVVSISAKWAQVKLPILEAIGGKIGT
HHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCHHHEEHHHHHHCCCCHHH
IVSGSFLILIAFFNLMVLIKLYKSLRLVKSGLDEQELNDLLLSRGFIANLVSPLFKKIVH
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHH
AWQMYPIGFLFGLGFDTATEIALIALSATAAQSNVSVAGIIALPVLFAAGMNVMDTTDSV
HHHHHHHHHHHHCCCCHHHHHHHHHEEHHHHHCCCCHHHHHHHHHHHHCCCCHHCCCHHH
MMSGAYTWAFDTPKRKAYYNLTVTFVSVIAAFLIGLVELGNVFADFTHVNSSFITWIQSI
HHCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHC
DLNWLGYGLVIGFILMWSLAYLFWKLFIQKNEQHA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]