Click here to switch to the map view.

The map label for this gene is supH [H]

Identifier: 116493402

GI number: 116493402

Start: 1654842

End: 1655651

Strand: Direct

Name: supH [H]

Synonym: PEPE_1674

Alternate gene names: 116493402

Gene position: 1654842-1655651 (Clockwise)

Preceding gene: 116493394

Following gene: 116493404

Centisome position: 90.31

GC content: 36.17

Gene sequence:

>810_bases
ATGATTGCTACGGATATGGATCAAACCTTCCTTGACAACCAAAATCAATACAATAAACAACGTTTTAGTGAAATTTTTCA
GGAAATGCAACGCCAAAATATTCACTTCGTCGCCGCTAGTGGTTCTCAACATGAGCGCCTTCAAGCGCTGTTTGAACCTC
AAGCTGAGCAGATGGACTTCATCTCCCAAAATGGCTCCATCATCTATTCCGGCAACGAATTAATCGATGTGCAACAAATC
TCTCCAAAACTTCTTCAAGACACACTAAATTCGATTAACCAGGCTTTTGGTCCAGATGAGATCTTAATTAATATTTGCGG
CTTAAATAGTTCATATGTAGATACAAATACTACTCCAGACGTTATGAATTTCATCAAAAATTTTTACAAAGAAATTCAAA
CTGTCGATGATATTAATCATTTTACTAAGAGCGGAATTGAAGATCCGATTGTCAAAATTGCTCTTAGCTTTGAAGATAGT
CCTAATATCAATCAAAAAATTGAGCGTTTACGAAGTCTTCTAGATCCTACGTTGGGGAGTTTAAGCTCGGGGTTCAATAC
TGAACTAATCGGTTTCAGTCACGTAGATAAATCAACTGCCCTTCAGCATTTAATGCAAAGATATAACGTAAACGCAGATG
AATTGGTGACTTTTGGTGACAACGAAAATGACTTACGAATGTTACAAATGACTCCTAATGGATATGCTATTCAAAATGCC
TTTTCTAAGGTCAAAGCAGTAGCTAACCATTTAACTCGATATGATAATGAACATGATGGTGTATTAGACACCCTAGAAAA
ACTATTATAA

Upstream 100 bases:

>100_bases
TAAAAAAGTGCTCGAAATATTGTAAGCACTTACTATTTTAACTATTTTGTTTTAAACTTATTATATAACTTTTAGAAATT
AGGTGACTATAGTGATAAAA

Downstream 100 bases:

>100_bases
AAAATCGGCGGTCAATTAACTTTTGAGCTTAATTTCAAAAGTTTTGACAACGCCGATTTTTTTAGTTAAATTCACTTAAA
ATTGCTTGGTACGCCACAAC

Product: HAD superfamily hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MIATDMDQTFLDNQNQYNKQRFSEIFQEMQRQNIHFVAASGSQHERLQALFEPQAEQMDFISQNGSIIYSGNELIDVQQI
SPKLLQDTLNSINQAFGPDEILINICGLNSSYVDTNTTPDVMNFIKNFYKEIQTVDDINHFTKSGIEDPIVKIALSFEDS
PNINQKIERLRSLLDPTLGSLSSGFNTELIGFSHVDKSTALQHLMQRYNVNADELVTFGDNENDLRMLQMTPNGYAIQNA
FSKVKAVANHLTRYDNEHDGVLDTLEKLL

Sequences:

>Translated_269_residues
MIATDMDQTFLDNQNQYNKQRFSEIFQEMQRQNIHFVAASGSQHERLQALFEPQAEQMDFISQNGSIIYSGNELIDVQQI
SPKLLQDTLNSINQAFGPDEILINICGLNSSYVDTNTTPDVMNFIKNFYKEIQTVDDINHFTKSGIEDPIVKIALSFEDS
PNINQKIERLRSLLDPTLGSLSSGFNTELIGFSHVDKSTALQHLMQRYNVNADELVTFGDNENDLRMLQMTPNGYAIQNA
FSKVKAVANHLTRYDNEHDGVLDTLEKLL
>Mature_269_residues
MIATDMDQTFLDNQNQYNKQRFSEIFQEMQRQNIHFVAASGSQHERLQALFEPQAEQMDFISQNGSIIYSGNELIDVQQI
SPKLLQDTLNSINQAFGPDEILINICGLNSSYVDTNTTPDVMNFIKNFYKEIQTVDDINHFTKSGIEDPIVKIALSFEDS
PNINQKIERLRSLLDPTLGSLSSGFNTELIGFSHVDKSTALQHLMQRYNVNADELVTFGDNENDLRMLQMTPNGYAIQNA
FSKVKAVANHLTRYDNEHDGVLDTLEKLL

Specific function: Catalyzes the hydrolysis of sugar phosphate to sugar and inorganic phosphate. Has a wide substrate specificity catalyzing the hydrolysis of fructose-1-P most efficiently, but it remains uncertain if this is the real substrate in vivo [H]

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family. SupH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787043, Length=270, Percent_Identity=28.1481481481481, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI87081790, Length=270, Percent_Identity=30.3703703703704, Blast_Score=119, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006379
- InterPro:   IPR000150 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.23 [H]

Molecular weight: Translated: 30560; Mature: 30560

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIATDMDQTFLDNQNQYNKQRFSEIFQEMQRQNIHFVAASGSQHERLQALFEPQAEQMDF
CCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHCCCHHHHHH
ISQNGSIIYSGNELIDVQQISPKLLQDTLNSINQAFGPDEILINICGLNSSYVDTNTTPD
HHCCCCEEECCCCEEEHHHCCHHHHHHHHHHHHHHCCCCHHEEEEECCCCCCCCCCCCHH
VMNFIKNFYKEIQTVDDINHFTKSGIEDPIVKIALSFEDSPNINQKIERLRSLLDPTLGS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCHHHHH
LSSGFNTELIGFSHVDKSTALQHLMQRYNVNADELVTFGDNENDLRMLQMTPNGYAIQNA
HHCCCCCCEEEHHHCCHHHHHHHHHHHHCCCHHHEEEECCCCCCEEEEEECCCCHHHHHH
FSKVKAVANHLTRYDNEHDGVLDTLEKLL
HHHHHHHHHHHHHCCCCCCCHHHHHHHHC
>Mature Secondary Structure
MIATDMDQTFLDNQNQYNKQRFSEIFQEMQRQNIHFVAASGSQHERLQALFEPQAEQMDF
CCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHCCCHHHHHH
ISQNGSIIYSGNELIDVQQISPKLLQDTLNSINQAFGPDEILINICGLNSSYVDTNTTPD
HHCCCCEEECCCCEEEHHHCCHHHHHHHHHHHHHHCCCCHHEEEEECCCCCCCCCCCCHH
VMNFIKNFYKEIQTVDDINHFTKSGIEDPIVKIALSFEDSPNINQKIERLRSLLDPTLGS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCHHHHH
LSSGFNTELIGFSHVDKSTALQHLMQRYNVNADELVTFGDNENDLRMLQMTPNGYAIQNA
HHCCCCCCEEEHHHCCHHHHHHHHHHHHCCCHHHEEEECCCCCCEEEEEECCCCHHHHHH
FSKVKAVANHLTRYDNEHDGVLDTLEKLL
HHHHHHHHHHHHHCCCCCCCHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]