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The map label for this gene is rpiA

Identifier: 116493244

GI number: 116493244

Start: 1473202

End: 1473888

Strand: Direct

Name: rpiA

Synonym: PEPE_1506

Alternate gene names: 116493244

Gene position: 1473202-1473888 (Clockwise)

Preceding gene: 116493243

Following gene: 116493245

Centisome position: 80.4

GC content: 38.28

Gene sequence:

>687_bases
ATGGATCAAAACGAATTAAAAAAACTAGTTGGCGAAGAAGCCGTTAAATTTATTGAAGATGGGATGACTGTGGGTTTAGG
TACCGGTTCTACTGTTAAATTTATGGTGGACGCTCTTGGTGAACGCGTTAAAAATGAAAATTTAAATATCGTTGGGGTCC
CAACTTCCGATCGTACAGCTGAACAAGCCCGTTCATTGGGCATTAATGTTAAATCTGTTGACGAGGTTGATCATATTGAT
TTAACCATTGATGGAGCTGATGAAATCAGTTCTGACTTCCAAGGTATCAAAGGTGGCGGTGCCGCTCACTTGTTTGAAAA
AATTGTTGCCACAAACTCAAAAAAAGTAATGTGGATTGTAGATGAATCTAAAATGGTTGATCACTTAGGGGCCTTCCCAC
TCCCTCTAGAAGTAATTCCATATGGTAGCAAACAAGTCTTCAAGAAGCTTGAAAAAGAAGGCCTTCATCCTGAATTTAGG
AAAAATGATGCTGGCGAATATGTTTTAACCGATTCTAAAAACTACGTAATTGATCTTCATCTTGGTGAAATTAAACACCC
GCATCAATTAGCAGATTATCTAATCAAACAAGTTGGTATTGTAGAACAAGGATTGTTCCTTGACATGGTTAATACTGTCA
TTGTTGGACGCCAAAATGGTCCAGAAGTTTTGACTGCTCGACCATAA

Upstream 100 bases:

>100_bases
ATATTTTCTCAACCATCCGGAACTTTCCGAATGGAACATGCACGACCAAATTACAGCAACTAAAATACAAAGCTTAGTAA
GTCGAAAGGAAGATTAAGAA

Downstream 100 bases:

>100_bases
TTCTAATCATTTACTAATTTTTTTAATTAGCGTATAATCATCACCAATATTAGGATGGAGTTGAAGATATTGAGTAAAGA
AATTTCACAAAATTTAATTG

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MDQNELKKLVGEEAVKFIEDGMTVGLGTGSTVKFMVDALGERVKNENLNIVGVPTSDRTAEQARSLGINVKSVDEVDHID
LTIDGADEISSDFQGIKGGGAAHLFEKIVATNSKKVMWIVDESKMVDHLGAFPLPLEVIPYGSKQVFKKLEKEGLHPEFR
KNDAGEYVLTDSKNYVIDLHLGEIKHPHQLADYLIKQVGIVEQGLFLDMVNTVIVGRQNGPEVLTARP

Sequences:

>Translated_228_residues
MDQNELKKLVGEEAVKFIEDGMTVGLGTGSTVKFMVDALGERVKNENLNIVGVPTSDRTAEQARSLGINVKSVDEVDHID
LTIDGADEISSDFQGIKGGGAAHLFEKIVATNSKKVMWIVDESKMVDHLGAFPLPLEVIPYGSKQVFKKLEKEGLHPEFR
KNDAGEYVLTDSKNYVIDLHLGEIKHPHQLADYLIKQVGIVEQGLFLDMVNTVIVGRQNGPEVLTARP
>Mature_228_residues
MDQNELKKLVGEEAVKFIEDGMTVGLGTGSTVKFMVDALGERVKNENLNIVGVPTSDRTAEQARSLGINVKSVDEVDHID
LTIDGADEISSDFQGIKGGGAAHLFEKIVATNSKKVMWIVDESKMVDHLGAFPLPLEVIPYGSKQVFKKLEKEGLHPEFR
KNDAGEYVLTDSKNYVIDLHLGEIKHPHQLADYLIKQVGIVEQGLFLDMVNTVIVGRQNGPEVLTARP

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=232, Percent_Identity=36.2068965517241, Blast_Score=118, Evalue=3e-27,
Organism=Escherichia coli, GI1789280, Length=221, Percent_Identity=41.6289592760181, Blast_Score=154, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI17551758, Length=214, Percent_Identity=33.6448598130841, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6324669, Length=223, Percent_Identity=30.9417040358744, Blast_Score=100, Evalue=3e-22,
Organism=Drosophila melanogaster, GI281364072, Length=216, Percent_Identity=31.0185185185185, Blast_Score=84, Evalue=9e-17,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_PEDPA (Q03E35)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_804979.1
- ProteinModelPortal:   Q03E35
- SMR:   Q03E35
- STRING:   Q03E35
- GeneID:   4417231
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_1506
- NMPDR:   fig|278197.10.peg.1327
- eggNOG:   COG0120
- HOGENOM:   HBG515603
- OMA:   MVVIADA
- PhylomeDB:   Q03E35
- ProtClustDB:   PRK00702
- BioCyc:   PPEN278197:PEPE_1506-MONOMER
- HAMAP:   MF_00170
- InterPro:   IPR014036
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF00455 DeoR; PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 25049; Mature: 25049

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQNELKKLVGEEAVKFIEDGMTVGLGTGSTVKFMVDALGERVKNENLNIVGVPTSDRTA
CCHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHH
EQARSLGINVKSVDEVDHIDLTIDGADEISSDFQGIKGGGAAHLFEKIVATNSKKVMWIV
HHHHHHCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEE
DESKMVDHLGAFPLPLEVIPYGSKQVFKKLEKEGLHPEFRKNDAGEYVLTDSKNYVIDLH
CCHHHHHHHCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCEEEEEE
LGEIKHPHQLADYLIKQVGIVEQGLFLDMVNTVIVGRQNGPEVLTARP
ECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHEEECCCCCEEEEECC
>Mature Secondary Structure
MDQNELKKLVGEEAVKFIEDGMTVGLGTGSTVKFMVDALGERVKNENLNIVGVPTSDRTA
CCHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHH
EQARSLGINVKSVDEVDHIDLTIDGADEISSDFQGIKGGGAAHLFEKIVATNSKKVMWIV
HHHHHHCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEE
DESKMVDHLGAFPLPLEVIPYGSKQVFKKLEKEGLHPEFRKNDAGEYVLTDSKNYVIDLH
CCHHHHHHHCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCEEEEEE
LGEIKHPHQLADYLIKQVGIVEQGLFLDMVNTVIVGRQNGPEVLTARP
ECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHEEECCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA