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The map label for this gene is hexR [C]

Identifier: 116493109

GI number: 116493109

Start: 1350158

End: 1350991

Strand: Direct

Name: hexR [C]

Synonym: PEPE_1363

Alternate gene names: 116493109

Gene position: 1350158-1350991 (Clockwise)

Preceding gene: 116493104

Following gene: 116493122

Centisome position: 73.68

GC content: 33.45

Gene sequence:

>834_bases
ATGGCAAATTTTAATTTAAGACTTCAAGCTTATCAAGCCAATTTTAGCGATAAGGAAAAAGAATTAGCACAATTTTTATT
AAAAAATCAGGCCCAAACTACCCAACTTACGATATCTGAACTTAGCCATAGAACTAATATCTCTACTGCGACTATTTCAC
GTTTTGCCAAGAATCTAGGTTTTGATAATTTTCAAGCTTTAAAACTCTGCATAGCTCAAAATATAGAAACTAATAATCCC
TATGTAGAAATCAGCCCTGCCGATTCTCCTAAAACCATGGCTAAAAAGATATTTAAATTGAATGTGGATACTTTAAATGC
TACTGAAAATGCTCTAAATGGAAAAGATTTGGATCAGTGTGTAAATCTAATTTTAAATACTAAAAAACTAGGTTTATTTG
GCTTAGGTGCTAGCAATATTGTTGCATTAAATGGATTTCATAAGTTTTTACGTACCACTATCGAACCCATCTATGCAAGT
GATTTTCATATGCAATTAATGGAAGCAGCCCGCCTCTCAAAAAATGATGTGATGTTGTTAGTATCTCATTCGGGGGAAAA
TCGGGATGCCCTCGCCCTAGCTGAAGTCGCTAAAGAACGTAATATTCCATTAATATTAATTACTAGTTCTGCTAACTCAA
CTCTTTCAAAAAAAGCTGATGTTACTCTTGTTTCAGTCGCTGAGGAATCACTTTACCGTCCGGATGCCTTACACGCACTC
ATTGCTCAAATTAGTATAATGGATACCTTATTTATGATGATTGCTATTAAGACTAAACGAAATATTGCTACCAATATTCG
ACATGAAATTGATAAAACTAGAAATAGACAATAA

Upstream 100 bases:

>100_bases
ATGAAAATATGTTACATATTGCAAGCGTTTACAAGAAAATTATTTTCTTATACAATTTTGATGTTATAATTAAATAAATC
ACAAACTCGAGGTAATCACG

Downstream 100 bases:

>100_bases
AAATTTCAAAATGCTGTTATAATGCTTTTATCAAACAAACTGGAGTCGTTACTGTACCTCAAAAGTTATTAGCAGAATAC
GCAATTGATATCCCCAAGAT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MANFNLRLQAYQANFSDKEKELAQFLLKNQAQTTQLTISELSHRTNISTATISRFAKNLGFDNFQALKLCIAQNIETNNP
YVEISPADSPKTMAKKIFKLNVDTLNATENALNGKDLDQCVNLILNTKKLGLFGLGASNIVALNGFHKFLRTTIEPIYAS
DFHMQLMEAARLSKNDVMLLVSHSGENRDALALAEVAKERNIPLILITSSANSTLSKKADVTLVSVAEESLYRPDALHAL
IAQISIMDTLFMMIAIKTKRNIATNIRHEIDKTRNRQ

Sequences:

>Translated_277_residues
MANFNLRLQAYQANFSDKEKELAQFLLKNQAQTTQLTISELSHRTNISTATISRFAKNLGFDNFQALKLCIAQNIETNNP
YVEISPADSPKTMAKKIFKLNVDTLNATENALNGKDLDQCVNLILNTKKLGLFGLGASNIVALNGFHKFLRTTIEPIYAS
DFHMQLMEAARLSKNDVMLLVSHSGENRDALALAEVAKERNIPLILITSSANSTLSKKADVTLVSVAEESLYRPDALHAL
IAQISIMDTLFMMIAIKTKRNIATNIRHEIDKTRNRQ
>Mature_276_residues
ANFNLRLQAYQANFSDKEKELAQFLLKNQAQTTQLTISELSHRTNISTATISRFAKNLGFDNFQALKLCIAQNIETNNPY
VEISPADSPKTMAKKIFKLNVDTLNATENALNGKDLDQCVNLILNTKKLGLFGLGASNIVALNGFHKFLRTTIEPIYASD
FHMQLMEAARLSKNDVMLLVSHSGENRDALALAEVAKERNIPLILITSSANSTLSKKADVTLVSVAEESLYRPDALHALI
AQISIMDTLFMMIAIKTKRNIATNIRHEIDKTRNRQ

Specific function: Represses The Expression Of The Hex Regulon (Zwf, Eda, Glp And Gap) (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=248, Percent_Identity=27.8225806451613, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI87082369, Length=250, Percent_Identity=26.4, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI87082130, Length=272, Percent_Identity=25.7352941176471, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1788767, Length=249, Percent_Identity=26.1044176706827, Blast_Score=90, Evalue=1e-19,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 30880; Mature: 30749

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANFNLRLQAYQANFSDKEKELAQFLLKNQAQTTQLTISELSHRTNISTATISRFAKNLG
CCCCEEEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
FDNFQALKLCIAQNIETNNPYVEISPADSPKTMAKKIFKLNVDTLNATENALNGKDLDQC
CCHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCHHCCCCCCHHHH
VNLILNTKKLGLFGLGASNIVALNGFHKFLRTTIEPIYASDFHMQLMEAARLSKNDVMLL
HHHHHCCCCCCEEECCCCCEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEE
VSHSGENRDALALAEVAKERNIPLILITSSANSTLSKKADVTLVSVAEESLYRPDALHAL
EECCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHCCCCEEEEEEHHHHCCCCHHHHHH
IAQISIMDTLFMMIAIKTKRNIATNIRHEIDKTRNRQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ANFNLRLQAYQANFSDKEKELAQFLLKNQAQTTQLTISELSHRTNISTATISRFAKNLG
CCCEEEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
FDNFQALKLCIAQNIETNNPYVEISPADSPKTMAKKIFKLNVDTLNATENALNGKDLDQC
CCHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCHHCCCCCCHHHH
VNLILNTKKLGLFGLGASNIVALNGFHKFLRTTIEPIYASDFHMQLMEAARLSKNDVMLL
HHHHHCCCCCCEEECCCCCEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEE
VSHSGENRDALALAEVAKERNIPLILITSSANSTLSKKADVTLVSVAEESLYRPDALHAL
EECCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHCCCCEEEEEEHHHHCCCCHHHHHH
IAQISIMDTLFMMIAIKTKRNIATNIRHEIDKTRNRQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]