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The map label for this gene is yclJ [H]

Identifier: 116493100

GI number: 116493100

Start: 1340948

End: 1341670

Strand: Reverse

Name: yclJ [H]

Synonym: PEPE_1354

Alternate gene names: 116493100

Gene position: 1341670-1340948 (Counterclockwise)

Preceding gene: 116493101

Following gene: 116493099

Centisome position: 73.22

GC content: 38.17

Gene sequence:

>723_bases
ATGCGTATATTGATGATTGAAGATAATAAATCTGTTTCCGATATGATGGGAATGTTTTTTAAAAAAGAAAGATGGAATGT
TACATTTGTGTATGATGGATTAAAAGCCATTGAAACTTTTAAAACCGATCCTGAACAATGGGACATCGTTTTACTTGATT
TAAATTTACCTGGAAAAGATGGTATGGAGGTAGCAGCTGAACTTCGACGCACGTCGCAGTCCATCCCCTTAATTATGTTG
ACAGCACGTGATTCAGAAAGTGATCAAGTTTTAGGCTTAGAAATGGGAGCCGATGAATATATTACTAAACCATTTAGTCC
TATTACGTTAATCGCTCGTATTAAGGCCTTGTACCGACGAGTGTCAATGAGTAGGGAAACGATGACGCAAGGTGCTCAGA
ATGCGAAATTCGATGTTAGAACGGCTCATCTTAAGATTAGTACATCTACTCGAGAGGTGTATTTAGACGAAAAGCTTATT
TCAGATTTAACCCCTAAAGAATTCGATTTACTTAAAACATTGGCGCAGAAGCCCATGCAGGTCTTCTCACGAGAACAACT
TCTACAAATAGTGTGGGATTATGAATATTATGGTGATGAACGTACGGTAGATGCCCATATTAAAAAGCTTCGCCAAAAAT
TAGAAGCAGTTGGTCCACAAGTGGTCCAAACGGTATGGGGAGTTGGCTATAAGTTTGATGATAGTAAAATCGATGAGGAT
TAG

Upstream 100 bases:

>100_bases
ACTAATTAAGTTTGTCTCTCTTTTTTGATATTATATTCACATTTTTTTCGATAAAAAAGGCTATACTTGATAAGGTAAAA
GGAACTGGAGGAGTTTTGAA

Downstream 100 bases:

>100_bases
TTAATATGAAATTGTTTTTTCAACAGATGATGGCCTTTTTATTAGTAACTCTGTCATCTTTATTGATCGTTGGATTGGTT
TTTATTCAGTTTACTAAAGA

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MRILMIEDNKSVSDMMGMFFKKERWNVTFVYDGLKAIETFKTDPEQWDIVLLDLNLPGKDGMEVAAELRRTSQSIPLIML
TARDSESDQVLGLEMGADEYITKPFSPITLIARIKALYRRVSMSRETMTQGAQNAKFDVRTAHLKISTSTREVYLDEKLI
SDLTPKEFDLLKTLAQKPMQVFSREQLLQIVWDYEYYGDERTVDAHIKKLRQKLEAVGPQVVQTVWGVGYKFDDSKIDED

Sequences:

>Translated_240_residues
MRILMIEDNKSVSDMMGMFFKKERWNVTFVYDGLKAIETFKTDPEQWDIVLLDLNLPGKDGMEVAAELRRTSQSIPLIML
TARDSESDQVLGLEMGADEYITKPFSPITLIARIKALYRRVSMSRETMTQGAQNAKFDVRTAHLKISTSTREVYLDEKLI
SDLTPKEFDLLKTLAQKPMQVFSREQLLQIVWDYEYYGDERTVDAHIKKLRQKLEAVGPQVVQTVWGVGYKFDDSKIDED
>Mature_240_residues
MRILMIEDNKSVSDMMGMFFKKERWNVTFVYDGLKAIETFKTDPEQWDIVLLDLNLPGKDGMEVAAELRRTSQSIPLIML
TARDSESDQVLGLEMGADEYITKPFSPITLIARIKALYRRVSMSRETMTQGAQNAKFDVRTAHLKISTSTREVYLDEKLI
SDLTPKEFDLLKTLAQKPMQVFSREQLLQIVWDYEYYGDERTVDAHIKKLRQKLEAVGPQVVQTVWGVGYKFDDSKIDED

Specific function: Could be member of the two-component regulatory system yclK/yclJ [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=234, Percent_Identity=38.8888888888889, Blast_Score=161, Evalue=3e-41,
Organism=Escherichia coli, GI1786599, Length=236, Percent_Identity=41.5254237288136, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1789809, Length=239, Percent_Identity=33.4728033472803, Blast_Score=142, Evalue=1e-35,
Organism=Escherichia coli, GI1790860, Length=233, Percent_Identity=34.3347639484979, Blast_Score=133, Evalue=9e-33,
Organism=Escherichia coli, GI1789402, Length=234, Percent_Identity=33.3333333333333, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=35.0649350649351, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1790863, Length=237, Percent_Identity=31.6455696202532, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI87082012, Length=233, Percent_Identity=32.1888412017167, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=32.034632034632, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI1786784, Length=237, Percent_Identity=30.8016877637131, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=31.0043668122271, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=33.8983050847458, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1787375, Length=235, Percent_Identity=31.4893617021277, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1786911, Length=239, Percent_Identity=29.2887029288703, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788521, Length=196, Percent_Identity=30.1020408163265, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27731; Mature: 27731

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILMIEDNKSVSDMMGMFFKKERWNVTFVYDGLKAIETFKTDPEQWDIVLLDLNLPGKD
CEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCHHHHHHHCCCCCCEEEEEEEECCCCCC
GMEVAAELRRTSQSIPLIMLTARDSESDQVLGLEMGADEYITKPFSPITLIARIKALYRR
HHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEECCCHHHHCCCCCHHHHHHHHHHHHHH
VSMSRETMTQGAQNAKFDVRTAHLKISTSTREVYLDEKLISDLTPKEFDLLKTLAQKPMQ
HHCCHHHHHCCCCCCEEEEEEEEEEEECCCHHEEEHHHHHHCCCCHHHHHHHHHHHHHHH
VFSREQLLQIVWDYEYYGDERTVDAHIKKLRQKLEAVGPQVVQTVWGVGYKFDDSKIDED
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHCCEEECCCCCCCC
>Mature Secondary Structure
MRILMIEDNKSVSDMMGMFFKKERWNVTFVYDGLKAIETFKTDPEQWDIVLLDLNLPGKD
CEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCHHHHHHHCCCCCCEEEEEEEECCCCCC
GMEVAAELRRTSQSIPLIMLTARDSESDQVLGLEMGADEYITKPFSPITLIARIKALYRR
HHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEECCCHHHHCCCCCHHHHHHHHHHHHHH
VSMSRETMTQGAQNAKFDVRTAHLKISTSTREVYLDEKLISDLTPKEFDLLKTLAQKPMQ
HHCCHHHHHCCCCCCEEEEEEEEEEEECCCHHEEEHHHHHHCCCCHHHHHHHHHHHHHHH
VFSREQLLQIVWDYEYYGDERTVDAHIKKLRQKLEAVGPQVVQTVWGVGYKFDDSKIDED
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]