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The map label for this gene is 116493023

Identifier: 116493023

GI number: 116493023

Start: 1264690

End: 1266249

Strand: Reverse

Name: 116493023

Synonym: PEPE_1275

Alternate gene names: NA

Gene position: 1266249-1264690 (Counterclockwise)

Preceding gene: 116493024

Following gene: 116493022

Centisome position: 69.1

GC content: 39.81

Gene sequence:

>1560_bases
ATGATAATTTTATATATTATCCTCGCAATCATCGCTATAGTTGTTGGCTATTGTGCAGGATTCTTTATGCACAAACGGCT
CATTGAAAAGCAAACTGCAAATGCCAGTAATTCGGCAGATGTAATTGTTGAAAATGCAAGAAAGCAAGCAGAAACGGAAC
GTCGTGAAAAGCTTCTAGAAGCCAAGGACGAGAGTCATCGCTATCGGGCGAAGGTGGAAAAAGAATTAAAAGAGCGACGG
GCTGAGCTTCAAAAGCAAGAAGATCGTTTACTTCAGAGAGAAGATTCTCTTGATCGTAAGGATAATTCCTTCGAAAAGAG
AGAGAATAGCCTAGAACGAAAAGAACAGAAACTTGCTCTAGACCAAAAGCATATCGATGAGCAACAACAAAAAGCATCAT
CACTCGTTGAAGAACGACAACAAGAACTTGAGCGAGTTTCCAATCTAACTCAAGAAGATGCAAAGAACTTAATTATTTCC
GAAACAGAAGCTAAGTTGGAAAAGGAAAGAGCGTTAATAATCAAGGAAGGTCTTGAAGATGCTGAAGCAGAAGCAGATCA
GACTGCCAGGAAACTTATCGCTGAAGCTATTCAACGCAGTGCGGCTGATATGGCATCTGAAACCACAATTACGGTGGTTT
CGTTGCCCAATGATGATATGAAGGGTAGAATTATCGGACGTGAAGGCCGTAATATTCGAAACTTCCAAAATGTCACGGGA
GTAGACTTGATCATTGATGACACTCCTGAAGCCGTGGTATTGAGTAGCTTTGACCCAATTCGTCGCGAAATTGCTCGAAT
TGCCTTAGACAAACTGATTCAAGATGGTCGGATTCATCCTGCTCGAATTGAGGAAATGGTTGAAAAAGCTAAAAAAGAAA
TGGATGACAATATTCGTAAGACTGGTGAACAAGCGGTCTTTGATTTGGGAATTCATTCTATGAACCCGGAACTAATTAAG
TTAATTGGACAATTAAAATATCGGACGAGTTATGGTCAAAATGTTTTAAACCATTCAATTGAAGTTGCTAATTTAGCAGG
TGTTTTAGCTGCTGAATTAGGTGAAGATGTTACTGTAGCAAAACGCGCAGGATTATTACACGATATTGGTAAAGCAGTAC
AACATGAAACTGATACTTCGCACGCTCAACTTGGAGTTGAGTTGGCTAAGAAGTATAAAGAAAGTGCAACGGTAATTAAT
GCAATTGCCGCTCATCACGATGGTGTTGAAGCACAGCATGTTATCTCCGTATTGGTTGCTGCAGCTAACTCGATTTCAGC
AGCGCGACCAGGGGCACGGAGTGATACACTACAAAGTTATATTCATCGTTTAGAAAAACTAGAACAGATTTCTAATAATT
TTGATGGAGTAAAGAAAAGTTACGCAATTCAAGCTGGACGTGAAGTTCGCGTTATCGTTAAACCTAATAAGATTAACGAT
TTGAAGGCGGTTATGTTGACCCACAATATTCGTAAGGCGATTGAAAAAGAGCTCGAATATGCTGGAAAAGTTAAAGTAAC
GGTTGTACGTGAAGTTCGAGCAGTTGATTATGCTAAGTAA

Upstream 100 bases:

>100_bases
TGACACTCTTATACCTAAATATTAAAATGATAATAAGTGTGAAAATCAAATAACATCATTCAAGAGATATAACTATGGTC
TTGATGATTTGGAGGCAAAG

Downstream 100 bases:

>100_bases
AGGAGAGTTGGACTAGCGGTCCGCTCTTTTTTTGTTATATGTTAGAATATCCATTGTTAATGTATTTTTTACGTATTTAA
AAATATGAGAGAAAAAGCTG

Product: HD superfamily hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 519; Mature: 519

Protein sequence:

>519_residues
MIILYIILAIIAIVVGYCAGFFMHKRLIEKQTANASNSADVIVENARKQAETERREKLLEAKDESHRYRAKVEKELKERR
AELQKQEDRLLQREDSLDRKDNSFEKRENSLERKEQKLALDQKHIDEQQQKASSLVEERQQELERVSNLTQEDAKNLIIS
ETEAKLEKERALIIKEGLEDAEAEADQTARKLIAEAIQRSAADMASETTITVVSLPNDDMKGRIIGREGRNIRNFQNVTG
VDLIIDDTPEAVVLSSFDPIRREIARIALDKLIQDGRIHPARIEEMVEKAKKEMDDNIRKTGEQAVFDLGIHSMNPELIK
LIGQLKYRTSYGQNVLNHSIEVANLAGVLAAELGEDVTVAKRAGLLHDIGKAVQHETDTSHAQLGVELAKKYKESATVIN
AIAAHHDGVEAQHVISVLVAAANSISAARPGARSDTLQSYIHRLEKLEQISNNFDGVKKSYAIQAGREVRVIVKPNKIND
LKAVMLTHNIRKAIEKELEYAGKVKVTVVREVRAVDYAK

Sequences:

>Translated_519_residues
MIILYIILAIIAIVVGYCAGFFMHKRLIEKQTANASNSADVIVENARKQAETERREKLLEAKDESHRYRAKVEKELKERR
AELQKQEDRLLQREDSLDRKDNSFEKRENSLERKEQKLALDQKHIDEQQQKASSLVEERQQELERVSNLTQEDAKNLIIS
ETEAKLEKERALIIKEGLEDAEAEADQTARKLIAEAIQRSAADMASETTITVVSLPNDDMKGRIIGREGRNIRNFQNVTG
VDLIIDDTPEAVVLSSFDPIRREIARIALDKLIQDGRIHPARIEEMVEKAKKEMDDNIRKTGEQAVFDLGIHSMNPELIK
LIGQLKYRTSYGQNVLNHSIEVANLAGVLAAELGEDVTVAKRAGLLHDIGKAVQHETDTSHAQLGVELAKKYKESATVIN
AIAAHHDGVEAQHVISVLVAAANSISAARPGARSDTLQSYIHRLEKLEQISNNFDGVKKSYAIQAGREVRVIVKPNKIND
LKAVMLTHNIRKAIEKELEYAGKVKVTVVREVRAVDYAK
>Mature_519_residues
MIILYIILAIIAIVVGYCAGFFMHKRLIEKQTANASNSADVIVENARKQAETERREKLLEAKDESHRYRAKVEKELKERR
AELQKQEDRLLQREDSLDRKDNSFEKRENSLERKEQKLALDQKHIDEQQQKASSLVEERQQELERVSNLTQEDAKNLIIS
ETEAKLEKERALIIKEGLEDAEAEADQTARKLIAEAIQRSAADMASETTITVVSLPNDDMKGRIIGREGRNIRNFQNVTG
VDLIIDDTPEAVVLSSFDPIRREIARIALDKLIQDGRIHPARIEEMVEKAKKEMDDNIRKTGEQAVFDLGIHSMNPELIK
LIGQLKYRTSYGQNVLNHSIEVANLAGVLAAELGEDVTVAKRAGLLHDIGKAVQHETDTSHAQLGVELAKKYKESATVIN
AIAAHHDGVEAQHVISVLVAAANSISAARPGARSDTLQSYIHRLEKLEQISNNFDGVKKSYAIQAGREVRVIVKPNKIND
LKAVMLTHNIRKAIEKELEYAGKVKVTVVREVRAVDYAK

Specific function: Catalyzes the hydrolysis of both 2',3'-cyclic AMP and 2',3'-cyclic GMP into 3'-AMP and 3'-GMP, respectively, at the 3'- terminal of RNA

COG id: COG1418

COG function: function code R; Predicted HD superfamily hydrolase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CNPD1_PEDPA (Q03EQ6)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_804758.1
- ProteinModelPortal:   Q03EQ6
- STRING:   Q03EQ6
- GeneID:   4417611
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_1275
- NMPDR:   fig|278197.10.peg.1117
- eggNOG:   COG1418
- HOGENOM:   HBG734610
- OMA:   HPGRIEE
- BioCyc:   PPEN278197:PEPE_1275-MONOMER
- HAMAP:   MF_00335
- InterPro:   IPR017705
- InterPro:   IPR022711
- InterPro:   IPR004087
- InterPro:   IPR004088
- InterPro:   IPR018111
- InterPro:   IPR003607
- InterPro:   IPR006675
- SMART:   SM00471
- SMART:   SM00322
- TIGRFAMs:   TIGR00277
- TIGRFAMs:   TIGR03319

Pfam domain/function: PF12072 DUF3552; PF00013 KH_1

EC number: =3.1.4.16

Molecular weight: Translated: 58363; Mature: 58363

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: PS50084 KH_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1746718c)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIILYIILAIIAIVVGYCAGFFMHKRLIEKQTANASNSADVIVENARKQAETERREKLLE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AKDESHRYRAKVEKELKERRAELQKQEDRLLQREDSLDRKDNSFEKRENSLERKEQKLAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
DQKHIDEQQQKASSLVEERQQELERVSNLTQEDAKNLIISETEAKLEKERALIIKEGLED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCH
AEAEADQTARKLIAEAIQRSAADMASETTITVVSLPNDDMKGRIIGREGRNIRNFQNVTG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEECCCCCCCHHHCCCCC
VDLIIDDTPEAVVLSSFDPIRREIARIALDKLIQDGRIHPARIEEMVEKAKKEMDDNIRK
CEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
TGEQAVFDLGIHSMNPELIKLIGQLKYRTSYGQNVLNHSIEVANLAGVLAAELGEDVTVA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHH
KRAGLLHDIGKAVQHETDTSHAQLGVELAKKYKESATVINAIAAHHDGVEAQHVISVLVA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
AANSISAARPGARSDTLQSYIHRLEKLEQISNNFDGVKKSYAIQAGREVRVIVKPNKIND
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEECCCCCCH
LKAVMLTHNIRKAIEKELEYAGKVKVTVVREVRAVDYAK
HHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCH
>Mature Secondary Structure
MIILYIILAIIAIVVGYCAGFFMHKRLIEKQTANASNSADVIVENARKQAETERREKLLE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AKDESHRYRAKVEKELKERRAELQKQEDRLLQREDSLDRKDNSFEKRENSLERKEQKLAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
DQKHIDEQQQKASSLVEERQQELERVSNLTQEDAKNLIISETEAKLEKERALIIKEGLED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCH
AEAEADQTARKLIAEAIQRSAADMASETTITVVSLPNDDMKGRIIGREGRNIRNFQNVTG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEECCCCCCCHHHCCCCC
VDLIIDDTPEAVVLSSFDPIRREIARIALDKLIQDGRIHPARIEEMVEKAKKEMDDNIRK
CEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
TGEQAVFDLGIHSMNPELIKLIGQLKYRTSYGQNVLNHSIEVANLAGVLAAELGEDVTVA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHH
KRAGLLHDIGKAVQHETDTSHAQLGVELAKKYKESATVINAIAAHHDGVEAQHVISVLVA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
AANSISAARPGARSDTLQSYIHRLEKLEQISNNFDGVKKSYAIQAGREVRVIVKPNKIND
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEECCCCCCH
LKAVMLTHNIRKAIEKELEYAGKVKVTVVREVRAVDYAK
HHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA