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The map label for this gene is yggV [C]

Identifier: 116493004

GI number: 116493004

Start: 1242152

End: 1242748

Strand: Reverse

Name: yggV [C]

Synonym: PEPE_1256

Alternate gene names: 116493004

Gene position: 1242748-1242152 (Counterclockwise)

Preceding gene: 116493005

Following gene: 116493002

Centisome position: 67.82

GC content: 37.69

Gene sequence:

>597_bases
ATGAATAATGAAATTTTGATTGCCACGAAAAATGATGGAAAATTAAAAGAATTTAAACAAATTTTTGAACAAAAGGGCAT
TGTTGTAAAATCGCTGAAAGATATTAATGATGACGTTGAAATAGTTGAAAATGGCTTGTCGTTTGAAGAAAATGCCCGTT
TAAAAGCAGACGGATACGCTAAATCAATTGGTATTCCAGTCCTTGCCGATGATTCAGGTTTGGAAATCGATGCTTTGAAT
GGACGCCCAGGAATTTTTTCGGCGCGTTACGCCGGTGATCACAATGATGCAGCTAACAATGCCAAAGTTCTTAGCGAATT
GGGTGGCATTCCAGATGAAAAACGTACAGCAACGTTTCATTCAACCGTAGTTGTGCGCAAACCAGATGGAAGTGAGTTAG
TGGCAAATGGAAATCTACGAGGACGAATTCTTGCTGTTCCGCGCGGTGACAACGGCTTTGGTTATGATCCTTTATTTTTT
GTGGAAGCAAAGAATAAAACTTTAGCTGAAATGACGCGTGAAGAGAAAAATAAAATTAGCCATCGTGCATTAGCAATTGA
AGATTTATTAGTAAACTTTGATAAATTCTGGGAATAA

Upstream 100 bases:

>100_bases
ATTCAACGGGTAATATTAAGAATTTTGAAGAAATAGCGCGGACATTCTTAAATCAAGATCTAAGAGTTGAAGAAGTTAAA
ATTGACTAGGAGAAATTAGA

Downstream 100 bases:

>100_bases
ATAAAAAAGTATGCCATCAACATTGAACCCGTAGTAGAGTGAATTGGATCTAACTTTGGGTGATTATAAGATGGCATACT
TTTTTACTAATTTTGAATTT

Product: xanthosine triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MNNEILIATKNDGKLKEFKQIFEQKGIVVKSLKDINDDVEIVENGLSFEENARLKADGYAKSIGIPVLADDSGLEIDALN
GRPGIFSARYAGDHNDAANNAKVLSELGGIPDEKRTATFHSTVVVRKPDGSELVANGNLRGRILAVPRGDNGFGYDPLFF
VEAKNKTLAEMTREEKNKISHRALAIEDLLVNFDKFWE

Sequences:

>Translated_198_residues
MNNEILIATKNDGKLKEFKQIFEQKGIVVKSLKDINDDVEIVENGLSFEENARLKADGYAKSIGIPVLADDSGLEIDALN
GRPGIFSARYAGDHNDAANNAKVLSELGGIPDEKRTATFHSTVVVRKPDGSELVANGNLRGRILAVPRGDNGFGYDPLFF
VEAKNKTLAEMTREEKNKISHRALAIEDLLVNFDKFWE
>Mature_198_residues
MNNEILIATKNDGKLKEFKQIFEQKGIVVKSLKDINDDVEIVENGLSFEENARLKADGYAKSIGIPVLADDSGLEIDALN
GRPGIFSARYAGDHNDAANNAKVLSELGGIPDEKRTATFHSTVVVRKPDGSELVANGNLRGRILAVPRGDNGFGYDPLFF
VEAKNKTLAEMTREEKNKISHRALAIEDLLVNFDKFWE

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Escherichia coli, GI1789324, Length=191, Percent_Identity=43.979057591623, Blast_Score=154, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI17556833, Length=194, Percent_Identity=32.4742268041237, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322529, Length=197, Percent_Identity=30.9644670050761, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 21831; Mature: 21831

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNEILIATKNDGKLKEFKQIFEQKGIVVKSLKDINDDVEIVENGLSFEENARLKADGYA
CCCCEEEEECCCCCHHHHHHHHHHCCEEEEHHHCCCCCHHHHHCCCCCCCCCEEEECCCH
KSIGIPVLADDSGLEIDALNGRPGIFSARYAGDHNDAANNAKVLSELGGIPDEKRTATFH
HHCCCEEEECCCCCEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCEEEEE
STVVVRKPDGSELVANGNLRGRILAVPRGDNGFGYDPLFFVEAKNKTLAEMTREEKNKIS
EEEEEECCCCCEEEECCCCCEEEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHH
HRALAIEDLLVNFDKFWE
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNNEILIATKNDGKLKEFKQIFEQKGIVVKSLKDINDDVEIVENGLSFEENARLKADGYA
CCCCEEEEECCCCCHHHHHHHHHHCCEEEEHHHCCCCCHHHHHCCCCCCCCCEEEECCCH
KSIGIPVLADDSGLEIDALNGRPGIFSARYAGDHNDAANNAKVLSELGGIPDEKRTATFH
HHCCCEEEECCCCCEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCEEEEE
STVVVRKPDGSELVANGNLRGRILAVPRGDNGFGYDPLFFVEAKNKTLAEMTREEKNKIS
EEEEEECCCCCEEEECCCCCEEEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHH
HRALAIEDLLVNFDKFWE
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12566566 [H]