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The map label for this gene is mecA

Identifier: 116492967

GI number: 116492967

Start: 1206186

End: 1206911

Strand: Reverse

Name: mecA

Synonym: PEPE_1206

Alternate gene names: 116492967

Gene position: 1206911-1206186 (Counterclockwise)

Preceding gene: 116492968

Following gene: 116492966

Centisome position: 65.87

GC content: 35.54

Gene sequence:

>726_bases
ATGGAAATGGAACGAATTAATGATGATACAATCCGAGTAACAATTAGTTCGGATGATTTAAATGAGCGAGGTGTGACGTT
CCTAGATTTACTTGATAATCATAAAGAAATCGAGAGCTTCTTTTATTCGGTATTAGAAGAGGTAGATACAGATCATCAGT
TTGCTAGTAATGATGCTGTTACTTTCCAAGTGCTACCTAACCGTAATGGGTTAGAACTATACATTAGTAAGAACCCAACT
GATGGCATGGAAGAAGCTATAAAATCAGTATCAAAAGACAATGCTCCTAGTAATGGGGAGATGGATGAAGTGTCGGACTT
TTTAAAGAGAAAATTGGCCGAAACAGATTCAAATGATAAAAATAACGATGATTCAAGCTATATGAGTGACGGAAATCCAG
CTGACCTAAATGGCTATGCTAATGGAGTTGGAAGTACGCAAAAATCAGTGATAGAGTTGGAGGATTTTGAAAGCTTACCA
AGTATTGCAGAATTGATAAAAACCAATAGTGGAATTGAGTCAGTTCTGTACCGTTATCATGACATATATTATTTAGAATT
AACTTTCTTTACCAGTGAAAATTCTCCTGAAACTATTAAGAATGACTTAGCAATCGCGTATGAATATGGAAATTCGACTA
TTGTTTCAAGCGAGGTTCTTAGAGAACATGGTGAAGTAGTTATGGATGGAGCAGCTTTAGAGCTGGCTAAGCGTTATTTT
AAATAA

Upstream 100 bases:

>100_bases
AACGGACAGGTGGTATTGTCTTATATTTTGTGGGATAATTATAGGAAACAAATATACTGTTATTTCCATTCAGTTTCGAT
AGAACTGGAGGTGCTGATTA

Downstream 100 bases:

>100_bases
TCAAAAATAGATTTTACCAAAACACAACATTAATTTGTTGTGTTTTTTTCGTGGGAAAGATCCCAAAAGCCGTATTTCTA
TATTGGGGTGAACCTAATGA

Product: adaptor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MEMERINDDTIRVTISSDDLNERGVTFLDLLDNHKEIESFFYSVLEEVDTDHQFASNDAVTFQVLPNRNGLELYISKNPT
DGMEEAIKSVSKDNAPSNGEMDEVSDFLKRKLAETDSNDKNNDDSSYMSDGNPADLNGYANGVGSTQKSVIELEDFESLP
SIAELIKTNSGIESVLYRYHDIYYLELTFFTSENSPETIKNDLAIAYEYGNSTIVSSEVLREHGEVVMDGAALELAKRYF
K

Sequences:

>Translated_241_residues
MEMERINDDTIRVTISSDDLNERGVTFLDLLDNHKEIESFFYSVLEEVDTDHQFASNDAVTFQVLPNRNGLELYISKNPT
DGMEEAIKSVSKDNAPSNGEMDEVSDFLKRKLAETDSNDKNNDDSSYMSDGNPADLNGYANGVGSTQKSVIELEDFESLP
SIAELIKTNSGIESVLYRYHDIYYLELTFFTSENSPETIKNDLAIAYEYGNSTIVSSEVLREHGEVVMDGAALELAKRYF
K
>Mature_241_residues
MEMERINDDTIRVTISSDDLNERGVTFLDLLDNHKEIESFFYSVLEEVDTDHQFASNDAVTFQVLPNRNGLELYISKNPT
DGMEEAIKSVSKDNAPSNGEMDEVSDFLKRKLAETDSNDKNNDDSSYMSDGNPADLNGYANGVGSTQKSVIELEDFESLP
SIAELIKTNSGIESVLYRYHDIYYLELTFFTSENSPETIKNDLAIAYEYGNSTIVSSEVLREHGEVVMDGAALELAKRYF
K

Specific function: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis

COG id: COG4862

COG function: function code OTN; Negative regulator of genetic competence, sporulation and motility

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mecA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MECA_PEDPA (Q03EW2)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_804702.1
- STRING:   Q03EW2
- GeneID:   4417587
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_1206
- NMPDR:   fig|278197.10.peg.1064
- eggNOG:   COG4862
- HOGENOM:   HBG514893
- OMA:   IHRLEEY
- ProtClustDB:   PRK02315
- BioCyc:   PPEN278197:PEPE_1206-MONOMER
- HAMAP:   MF_01124
- InterPro:   IPR008681
- PIRSF:   PIRSF029008

Pfam domain/function: PF05389 MecA

EC number: NA

Molecular weight: Translated: 27095; Mature: 27095

Theoretical pI: Translated: 4.00; Mature: 4.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMERINDDTIRVTISSDDLNERGVTFLDLLDNHKEIESFFYSVLEEVDTDHQFASNDAV
CCCCCCCCCEEEEEEECCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCE
TFQVLPNRNGLELYISKNPTDGMEEAIKSVSKDNAPSNGEMDEVSDFLKRKLAETDSNDK
EEEECCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
NNDDSSYMSDGNPADLNGYANGVGSTQKSVIELEDFESLPSIAELIKTNSGIESVLYRYH
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHC
DIYYLELTFFTSENSPETIKNDLAIAYEYGNSTIVSSEVLREHGEVVMDGAALELAKRYF
CEEEEEEEEEECCCCCHHHHCCEEEEEECCCCEEHHHHHHHHCCCEEECHHHHHHHHHHC
K
C
>Mature Secondary Structure
MEMERINDDTIRVTISSDDLNERGVTFLDLLDNHKEIESFFYSVLEEVDTDHQFASNDAV
CCCCCCCCCEEEEEEECCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCE
TFQVLPNRNGLELYISKNPTDGMEEAIKSVSKDNAPSNGEMDEVSDFLKRKLAETDSNDK
EEEECCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
NNDDSSYMSDGNPADLNGYANGVGSTQKSVIELEDFESLPSIAELIKTNSGIESVLYRYH
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHC
DIYYLELTFFTSENSPETIKNDLAIAYEYGNSTIVSSEVLREHGEVVMDGAALELAKRYF
CEEEEEEEEEECCCCCHHHHCCEEEEEECCCCEEHHHHHHHHCCCEEECHHHHHHHHHHC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA