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The map label for this gene is mraY

Identifier: 116492949

GI number: 116492949

Start: 1188861

End: 1189817

Strand: Reverse

Name: mraY

Synonym: PEPE_1188

Alternate gene names: 116492949

Gene position: 1189817-1188861 (Counterclockwise)

Preceding gene: 116492950

Following gene: 116492948

Centisome position: 64.93

GC content: 35.63

Gene sequence:

>957_bases
ATGATTAATGGAACAGCTTTAATACTAGGTGCGCTAGTAACATTAGTGGGGATGCCCCAATTTATCAATTACTTTAGAGT
CCGGAATGAAGGACAGATGATTCGTGAAGAGGGACCTAAATGGCATCAAAAAAAATCTGGAACACCAACCATGGGTGGAA
TGGTGTTTATCATTGCTATCATTATTGCTAGTTTAGTAACTGGTGTGATTTTCCACGGGGCAAAAGTGAGCCTTTTAATG
TTACTTTTTGTTTTAGTTGAATTTGGATTGATTGGTTGCTGGGATGATAGTATTAAGTTGTTAAAGCGCCAAAATGAAGG
TTTTAAAGCTTGGCAAAAGCTTTTAGGACAAATTATTGGAGGACTAATTTTCTTTCTAGTGATTAAGGAGACTGGAGTGG
CATTACAATTAAATATCCCTGGCTTAGGTATTTGGCACCTAGGCGGCTGGTATGCATTGTTTGTTATTTTCTGGTTAACT
GGATTTTCCAATGCCGTAAATCTTTCAGATGGATTAGATGGATTAGTAGCAGGATTATCGACGATTGCTTTTGGAACGTA
TGCAATTATTGCAGCTCACCAACAAAATATTCCAGTAATGATTTTCTGTATGGCAGTAGTGGGCTCAATGCTAGGATTCT
TAGTTTTTAACCATAAACCAGCTAAAATTTTTATGGGTGATATGGGATCTCTTGCCTTAGGGGGAGCTTTGGCAGCTGTC
TCAATTCTTTTAAATCAGGAATTATCATTGATTTTAATCGGGATTGTTTTTGTACTAGAAACTTTAAGTGTTATTCTCCA
AGTACTTTCTTTTAAATTAACTGGACATCGTATTTTTAAAATGAGTCCGATTCATCATCATTTTGAAATGTTAGGTTGGA
GCGAATGGAAAGTAGATATTGTATTTTGGATAGTTGGTTTAATCGGATCCATAATTACGTTAATTAGTATTTTATAG

Upstream 100 bases:

>100_bases
AATGGTTTTGTTTCTGGGCAATCGGTGGCCAAGGGTGGGCCAATAAAATCTGGCATGACCATGACTGTAAGTCTTAAGAA
GTAGAGATTAGGAGAGAAAA

Downstream 100 bases:

>100_bases
GGAGTCTTTAATGATGAAGTCAGTAGAAGATTTGGAAGATAAAAATGTTCTAGTTTTAGGAATGGCCAAGAGCGGAATAA
GCGCCGCTCTTTTATTACAT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MINGTALILGALVTLVGMPQFINYFRVRNEGQMIREEGPKWHQKKSGTPTMGGMVFIIAIIIASLVTGVIFHGAKVSLLM
LLFVLVEFGLIGCWDDSIKLLKRQNEGFKAWQKLLGQIIGGLIFFLVIKETGVALQLNIPGLGIWHLGGWYALFVIFWLT
GFSNAVNLSDGLDGLVAGLSTIAFGTYAIIAAHQQNIPVMIFCMAVVGSMLGFLVFNHKPAKIFMGDMGSLALGGALAAV
SILLNQELSLILIGIVFVLETLSVILQVLSFKLTGHRIFKMSPIHHHFEMLGWSEWKVDIVFWIVGLIGSIITLISIL

Sequences:

>Translated_318_residues
MINGTALILGALVTLVGMPQFINYFRVRNEGQMIREEGPKWHQKKSGTPTMGGMVFIIAIIIASLVTGVIFHGAKVSLLM
LLFVLVEFGLIGCWDDSIKLLKRQNEGFKAWQKLLGQIIGGLIFFLVIKETGVALQLNIPGLGIWHLGGWYALFVIFWLT
GFSNAVNLSDGLDGLVAGLSTIAFGTYAIIAAHQQNIPVMIFCMAVVGSMLGFLVFNHKPAKIFMGDMGSLALGGALAAV
SILLNQELSLILIGIVFVLETLSVILQVLSFKLTGHRIFKMSPIHHHFEMLGWSEWKVDIVFWIVGLIGSIITLISIL
>Mature_318_residues
MINGTALILGALVTLVGMPQFINYFRVRNEGQMIREEGPKWHQKKSGTPTMGGMVFIIAIIIASLVTGVIFHGAKVSLLM
LLFVLVEFGLIGCWDDSIKLLKRQNEGFKAWQKLLGQIIGGLIFFLVIKETGVALQLNIPGLGIWHLGGWYALFVIFWLT
GFSNAVNLSDGLDGLVAGLSTIAFGTYAIIAAHQQNIPVMIFCMAVVGSMLGFLVFNHKPAKIFMGDMGSLALGGALAAV
SILLNQELSLILIGIVFVLETLSVILQVLSFKLTGHRIFKMSPIHHHFEMLGWSEWKVDIVFWIVGLIGSIITLISIL

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=320, Percent_Identity=42.1875, Blast_Score=202, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_PEDPA (Q03EY0)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_804684.1
- STRING:   Q03EY0
- GeneID:   4417921
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_1188
- NMPDR:   fig|278197.10.peg.1046
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- PhylomeDB:   Q03EY0
- BioCyc:   PPEN278197:PEPE_1188-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 34778; Mature: 34778

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x17d19d40)-; HASH(0x181c0938)-; HASH(0x180fee58)-; HASH(0x181bf73c)-; HASH(0x181bf8d4)-; HASH(0x180fee70)-; HASH(0x17090e20)-; HASH(0x17569650)-; HASH(0x14806b74)-; HASH(0x1817d448)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINGTALILGALVTLVGMPQFINYFRVRNEGQMIREEGPKWHQKKSGTPTMGGMVFIIAI
CCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHCCCCHHHCCCCCCCHHHHHHHHHH
IIASLVTGVIFHGAKVSLLMLLFVLVEFGLIGCWDDSIKLLKRQNEGFKAWQKLLGQIIG
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEECCHHHHHHHHHCCCCHHHHHHHHHHHHH
GLIFFLVIKETGVALQLNIPGLGIWHLGGWYALFVIFWLTGFSNAVNLSDGLDGLVAGLS
HHHHHHHHHCCCEEEEEECCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
TIAFGTYAIIAAHQQNIPVMIFCMAVVGSMLGFLVFNHKPAKIFMGDMGSLALGGALAAV
HHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHH
SILLNQELSLILIGIVFVLETLSVILQVLSFKLTGHRIFKMSPIHHHFEMLGWSEWKVDI
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHCCCCCHHHHH
VFWIVGLIGSIITLISIL
HHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MINGTALILGALVTLVGMPQFINYFRVRNEGQMIREEGPKWHQKKSGTPTMGGMVFIIAI
CCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHCCCCHHHCCCCCCCHHHHHHHHHH
IIASLVTGVIFHGAKVSLLMLLFVLVEFGLIGCWDDSIKLLKRQNEGFKAWQKLLGQIIG
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEECCHHHHHHHHHCCCCHHHHHHHHHHHHH
GLIFFLVIKETGVALQLNIPGLGIWHLGGWYALFVIFWLTGFSNAVNLSDGLDGLVAGLS
HHHHHHHHHCCCEEEEEECCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
TIAFGTYAIIAAHQQNIPVMIFCMAVVGSMLGFLVFNHKPAKIFMGDMGSLALGGALAAV
HHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHH
SILLNQELSLILIGIVFVLETLSVILQVLSFKLTGHRIFKMSPIHHHFEMLGWSEWKVDI
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHCCCCCHHHHH
VFWIVGLIGSIITLISIL
HHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA