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The map label for this gene is gpmB [H]

Identifier: 116492932

GI number: 116492932

Start: 1171913

End: 1172587

Strand: Reverse

Name: gpmB [H]

Synonym: PEPE_1171

Alternate gene names: 116492932

Gene position: 1172587-1171913 (Counterclockwise)

Preceding gene: 116492933

Following gene: 116492931

Centisome position: 63.99

GC content: 35.56

Gene sequence:

>675_bases
TTGACGAAATTATATTTTATTAGACACGGTAAAACAGAATGGAATTTAGAGGGACGCTATCAAGGTGCCAATGGTGATTC
TCCACTATTGAAAGAAAGCTACACGGAAATTTCACAATTAGCTAGTTTTCTTGCACCTAATAAATTTCAACATATTTATG
CCAGTCCTTTACGACGTGCTAGAGTAACAGCTACGACATTACAACATGAGTTGGATGAATTACAAGGTTATCCAACGCCA
ATTACTATTTCTAGTAGGTTAAAAGAGTTCAATCTAGGTATTATGGAAGGAATGAAATTCGTCGATGTTGAGCGGGAATA
TACAGATGAAGTGGATGCATTCAGAAACCACCCAGATCGTTATGATCCTACCAAAATTAAGGGAGAAACTTTTCAACATT
TAGTAAAACGTATGAAACCTACTATTTTGCGTATTTGTGAAAAGTATCCTGCTAAAAATGATAATGTAATTATAGTAAGC
CACGGAGCGGCTTTAAATGCTCTAATTAATTCACTATTAGAGGTTCCGTTAGCTGATTTAAGGAAACGTGGCGGTTTAGC
CAATACGAGTACGACTGTCCTAGCAAGTAATGACTTAGGAAAGTCTTTTGAATTAGTTGATTGGAATAATACTAGTTACT
TAAAGAAGCGCATTGACCCAACAGATGTAATTTAA

Upstream 100 bases:

>100_bases
AAGAATCAGACTTAGTCTGGTTCTTTTTTTGTTTTTTGGTAACCTAGGATTCATTTAATGTTAAAATTATTAGTAACTAT
GTAAAAGAAGGACAAGAATT

Downstream 100 bases:

>100_bases
TGTAGGTGAAAAAATGACTGAAGATAAGAAAAAACAAGATATAGTTAAAGATTTGATTGATAAAATCGATCAAAATCCGC
AAGAAGCTGAAAATTATTAT

Product: fructose-2,6-bisphosphatase

Products: NA

Alternate protein names: PGAM; Phosphoglyceromutase [H]

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MTKLYFIRHGKTEWNLEGRYQGANGDSPLLKESYTEISQLASFLAPNKFQHIYASPLRRARVTATTLQHELDELQGYPTP
ITISSRLKEFNLGIMEGMKFVDVEREYTDEVDAFRNHPDRYDPTKIKGETFQHLVKRMKPTILRICEKYPAKNDNVIIVS
HGAALNALINSLLEVPLADLRKRGGLANTSTTVLASNDLGKSFELVDWNNTSYLKKRIDPTDVI

Sequences:

>Translated_224_residues
MTKLYFIRHGKTEWNLEGRYQGANGDSPLLKESYTEISQLASFLAPNKFQHIYASPLRRARVTATTLQHELDELQGYPTP
ITISSRLKEFNLGIMEGMKFVDVEREYTDEVDAFRNHPDRYDPTKIKGETFQHLVKRMKPTILRICEKYPAKNDNVIIVS
HGAALNALINSLLEVPLADLRKRGGLANTSTTVLASNDLGKSFELVDWNNTSYLKKRIDPTDVI
>Mature_223_residues
TKLYFIRHGKTEWNLEGRYQGANGDSPLLKESYTEISQLASFLAPNKFQHIYASPLRRARVTATTLQHELDELQGYPTPI
TISSRLKEFNLGIMEGMKFVDVEREYTDEVDAFRNHPDRYDPTKIKGETFQHLVKRMKPTILRICEKYPAKNDNVIIVSH
GAALNALINSLLEVPLADLRKRGGLANTSTTVLASNDLGKSFELVDWNNTSYLKKRIDPTDVI

Specific function: Unknown

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. GpmB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790856, Length=194, Percent_Identity=31.9587628865979, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1786857, Length=174, Percent_Identity=29.3103448275862, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25145314, Length=179, Percent_Identity=27.9329608938547, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322306, Length=176, Percent_Identity=25, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR023086 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 25512; Mature: 25381

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLYFIRHGKTEWNLEGRYQGANGDSPLLKESYTEISQLASFLAPNKFQHIYASPLRRA
CCEEEEEECCCEEECCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
RVTATTLQHELDELQGYPTPITISSRLKEFNLGIMEGMKFVDVEREYTDEVDAFRNHPDR
HHHHHHHHHHHHHHCCCCCCEEHHHHHHHHCCHHHHCCHHEECCHHHHHHHHHHHCCCCC
YDPTKIKGETFQHLVKRMKPTILRICEKYPAKNDNVIIVSHGAALNALINSLLEVPLADL
CCCCCCCCHHHHHHHHHHCHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHCCHHHH
RKRGGLANTSTTVLASNDLGKSFELVDWNNTSYLKKRIDPTDVI
HHHCCCCCCCEEEEECCCCCCCEEEEECCCHHHHHHCCCHHCCC
>Mature Secondary Structure 
TKLYFIRHGKTEWNLEGRYQGANGDSPLLKESYTEISQLASFLAPNKFQHIYASPLRRA
CEEEEEECCCEEECCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
RVTATTLQHELDELQGYPTPITISSRLKEFNLGIMEGMKFVDVEREYTDEVDAFRNHPDR
HHHHHHHHHHHHHHCCCCCCEEHHHHHHHHCCHHHHCCHHEECCHHHHHHHHHHHCCCCC
YDPTKIKGETFQHLVKRMKPTILRICEKYPAKNDNVIIVSHGAALNALINSLLEVPLADL
CCCCCCCCHHHHHHHHHHCHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHCCHHHH
RKRGGLANTSTTVLASNDLGKSFELVDWNNTSYLKKRIDPTDVI
HHHCCCCCCCEEEEECCCCCCCEEEEECCCHHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA