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The map label for this gene is fabZ [H]

Identifier: 116492627

GI number: 116492627

Start: 864075

End: 864488

Strand: Direct

Name: fabZ [H]

Synonym: PEPE_0861

Alternate gene names: 116492627

Gene position: 864075-864488 (Clockwise)

Preceding gene: 116492626

Following gene: 116492628

Centisome position: 47.16

GC content: 37.44

Gene sequence:

>414_bases
ATGGAAATTAATGTTCAAGATATTATTCCTCAACGTCCTCCTTTTCAAATGATTGATCAATTAGTTGATCTTGAAGCAGG
AAAAAAGGCGGTCGCTGAAAAGAAAGTTACCATCAATGAATGGTTTTTTAATAATGGCAACGAGCTCTGCATGCCTGAGC
CACTCTTAGTCGAGGCTTTAGCACAAACGGGAGCTTGTGCACTTTTATCAAACGAAGCATTTGTGGGAAAAAATGCTTTC
TTTGGCGGAATTAAACAAGCTGAATTTTCAAATAGAGTTGTTCCTGGCAATCGACTTACTTTAACGGTTGAATTAACCAA
AATGAAAAGACAAATCGGTACTGGTCATGGGGTTATTGTTAATGAAAATAACGAACTGATCTGTGAAGCTGATTTAACTT
TCATTGTGGGCTAG

Upstream 100 bases:

>100_bases
CACCAGTTGATGGTGAAGTCGTAGAACTCTTAGTTGAAAATGGATCGATGGTTGAATACGATCAACCAATTGCTCGTGTT
CGTAAAGTTGGAGATAATTA

Downstream 100 bases:

>100_bases
GAACAGGGAGGCTATCTATGTTTCAAAAGGTTTTAGTTGCTAATCGTGGTGAAATCGCGGTCCAAATTATCCGCGCCTTA
CACGAAATGGATATCGCTGC

Product: 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 137; Mature: 137

Protein sequence:

>137_residues
MEINVQDIIPQRPPFQMIDQLVDLEAGKKAVAEKKVTINEWFFNNGNELCMPEPLLVEALAQTGACALLSNEAFVGKNAF
FGGIKQAEFSNRVVPGNRLTLTVELTKMKRQIGTGHGVIVNENNELICEADLTFIVG

Sequences:

>Translated_137_residues
MEINVQDIIPQRPPFQMIDQLVDLEAGKKAVAEKKVTINEWFFNNGNELCMPEPLLVEALAQTGACALLSNEAFVGKNAF
FGGIKQAEFSNRVVPGNRLTLTVELTKMKRQIGTGHGVIVNENNELICEADLTFIVG
>Mature_137_residues
MEINVQDIIPQRPPFQMIDQLVDLEAGKKAVAEKKVTINEWFFNNGNELCMPEPLLVEALAQTGACALLSNEAFVGKNAF
FGGIKQAEFSNRVVPGNRLTLTVELTKMKRQIGTGHGVIVNENNELICEADLTFIVG

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=133, Percent_Identity=32.3308270676692, Blast_Score=70, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 15075; Mature: 15075

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEINVQDIIPQRPPFQMIDQLVDLEAGKKAVAEKKVTINEWFFNNGNELCMPEPLLVEAL
CCCCHHHCCCCCCCHHHHHHHHCCCCCCHHHHHCCEEEEEEEECCCCCCCCCCHHHHHHH
AQTGACALLSNEAFVGKNAFFGGIKQAEFSNRVVPGNRLTLTVELTKMKRQIGTGHGVIV
HCCCCEEEECCCCEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEHHHHHHHHCCCCCEEE
NENNELICEADLTFIVG
ECCCCEEEEECEEEEEC
>Mature Secondary Structure
MEINVQDIIPQRPPFQMIDQLVDLEAGKKAVAEKKVTINEWFFNNGNELCMPEPLLVEAL
CCCCHHHCCCCCCCHHHHHHHHCCCCCCHHHHHCCEEEEEEEECCCCCCCCCCHHHHHHH
AQTGACALLSNEAFVGKNAFFGGIKQAEFSNRVVPGNRLTLTVELTKMKRQIGTGHGVIV
HCCCCEEEECCCCEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEHHHHHHHHCCCCCEEE
NENNELICEADLTFIVG
ECCCCEEEEECEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA