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The map label for this gene is ftsY [H]

Identifier: 116492611

GI number: 116492611

Start: 852001

End: 853221

Strand: Direct

Name: ftsY [H]

Synonym: PEPE_0844

Alternate gene names: 116492611

Gene position: 852001-853221 (Clockwise)

Preceding gene: 116492610

Following gene: 116492612

Centisome position: 46.5

GC content: 39.64

Gene sequence:

>1221_bases
ATGGCATGGTTTTTTGGTAGAAAAAAGAAAAAAGAACAAAAGGTTGAACAAGAACCAGCTTCACAGGTTCAATCTGAATC
GATTAGTACAACAGTGAATAAGGATTCTTCAAGTGAGACTCATTCAGAGAGTCAAAGTACAATTGCGTCACAGGCTGCTG
TTGAAAAGCCAGTCCAAGCAGTAGAAACAAATCAAATTGAGGAGCCCACTTCTTCAACAGAAGGAGCTTCGACGTCTGAA
GTTAAAACTGAAACACAGACTAGTTCAGCTCCAGATAATGGGTTGGATGAAGCAGAACGCTATGACCGCGGTTTGGAACG
TTCAAGGAAATCATTTGGACAAAAATTATCAGCCTTATTTACGAATTTTTCTGGAGTAGATGAAGATTTTTATGATGATT
TGGAAGAAACATTAATCGAAGCTGATGTCGGATTTGATACAGCACTTGAAATCAGTGAGGAAGTTCGGGATGAAATCGAA
TTTGAACATGTTTCAGATCCTGACCAAATTTCTCAATTAATAGTTCGTCGCTTAGTGGCTCTGTATACTAGAAATGGTAG
TGCAGAAGATAATCATTTGGTCTTTAGTAAGGAGGGTCCAACCGTATTCCTCTTTGTAGGTGTCAATGGCGTTGGGAAGA
CAACTAGTATTGGAAAAATGGCCGCCCGCTTTAAAGGACGTGGACGTAAAGTCTTGCTTGCAGCCTGTGATACATTCCGG
GCAGGAGCAATCCAACAGTTGCAAGAATGGGGCAAACGCGATGGAGTCGATGTGGTGGCTGGTAAAGAGCAATCAGATCC
TGCTTCAGTAGCTTTCGAAGCTGTTAAAAAAGCTAAAGAAGAAAATTACGATTTATTACTAGTTGATACAGCTGGTCGTC
TTCAAAACAAGGTTAATTTGATGAATGAGTTGGATAAAATCAAGCGCGTAATTAGTCGTGAAATTCCAGACGCTCCGCAA
GAAACGTTGTTAGTTTTGGATTCAACTACGGGACAAAATGCCTTAACACAGGCTAAGGCATTTTTAGAAACTACGAATGT
TACAGGGATTATTTTAACTAAGTTAGATGGAACGGCTAAAGGTGGAATTGTGTTAGCAATTAGAAATCAATTACATTTAG
CAGTTAAATACGTTGGTTTAGGAGAGACGGTGGACGATCTTAGTCCATTTAATCCAGAACAATACGTAAGTGGACTCTTT
AAGGGTCTAATGGAAGATTAA

Upstream 100 bases:

>100_bases
AAGCCGACGTTTTGTATGGTGTTACAATGCAGGAATCAGGAGTTTCAAAAATGGTATCTGTTTCAATGGATGAGGCGGAA
TAAAGAAAGCAGGTGTAATA

Downstream 100 bases:

>100_bases
CGCCAATGGAAATCGAAAAAAATAATCGCATTAATAGCTTGTTGGAATTTTATGAACAGTTATTGACTCCAAAACAAAAG
GAGTATATAACACTGTATTA

Product: signal recognition particle-docking protein FtsY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MAWFFGRKKKKEQKVEQEPASQVQSESISTTVNKDSSSETHSESQSTIASQAAVEKPVQAVETNQIEEPTSSTEGASTSE
VKTETQTSSAPDNGLDEAERYDRGLERSRKSFGQKLSALFTNFSGVDEDFYDDLEETLIEADVGFDTALEISEEVRDEIE
FEHVSDPDQISQLIVRRLVALYTRNGSAEDNHLVFSKEGPTVFLFVGVNGVGKTTSIGKMAARFKGRGRKVLLAACDTFR
AGAIQQLQEWGKRDGVDVVAGKEQSDPASVAFEAVKKAKEENYDLLLVDTAGRLQNKVNLMNELDKIKRVISREIPDAPQ
ETLLVLDSTTGQNALTQAKAFLETTNVTGIILTKLDGTAKGGIVLAIRNQLHLAVKYVGLGETVDDLSPFNPEQYVSGLF
KGLMED

Sequences:

>Translated_406_residues
MAWFFGRKKKKEQKVEQEPASQVQSESISTTVNKDSSSETHSESQSTIASQAAVEKPVQAVETNQIEEPTSSTEGASTSE
VKTETQTSSAPDNGLDEAERYDRGLERSRKSFGQKLSALFTNFSGVDEDFYDDLEETLIEADVGFDTALEISEEVRDEIE
FEHVSDPDQISQLIVRRLVALYTRNGSAEDNHLVFSKEGPTVFLFVGVNGVGKTTSIGKMAARFKGRGRKVLLAACDTFR
AGAIQQLQEWGKRDGVDVVAGKEQSDPASVAFEAVKKAKEENYDLLLVDTAGRLQNKVNLMNELDKIKRVISREIPDAPQ
ETLLVLDSTTGQNALTQAKAFLETTNVTGIILTKLDGTAKGGIVLAIRNQLHLAVKYVGLGETVDDLSPFNPEQYVSGLF
KGLMED
>Mature_405_residues
AWFFGRKKKKEQKVEQEPASQVQSESISTTVNKDSSSETHSESQSTIASQAAVEKPVQAVETNQIEEPTSSTEGASTSEV
KTETQTSSAPDNGLDEAERYDRGLERSRKSFGQKLSALFTNFSGVDEDFYDDLEETLIEADVGFDTALEISEEVRDEIEF
EHVSDPDQISQLIVRRLVALYTRNGSAEDNHLVFSKEGPTVFLFVGVNGVGKTTSIGKMAARFKGRGRKVLLAACDTFRA
GAIQQLQEWGKRDGVDVVAGKEQSDPASVAFEAVKKAKEENYDLLLVDTAGRLQNKVNLMNELDKIKRVISREIPDAPQE
TLLVLDSTTGQNALTQAKAFLETTNVTGIILTKLDGTAKGGIVLAIRNQLHLAVKYVGLGETVDDLSPFNPEQYVSGLFK
GLMED

Specific function: Required for normal cell growth and morphogenesis; translocation of at least 1 protein is impaired in its absence [H]

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=267, Percent_Identity=32.2097378277154, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI226371618, Length=199, Percent_Identity=35.678391959799, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI23308697, Length=307, Percent_Identity=29.9674267100977, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI295424842, Length=307, Percent_Identity=29.9674267100977, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI89061728, Length=137, Percent_Identity=35.036496350365, Blast_Score=94, Evalue=3e-19,
Organism=Escherichia coli, GI1789874, Length=301, Percent_Identity=42.1926910299003, Blast_Score=241, Evalue=4e-65,
Organism=Escherichia coli, GI1788963, Length=298, Percent_Identity=35.5704697986577, Blast_Score=158, Evalue=7e-40,
Organism=Caenorhabditis elegans, GI17539958, Length=267, Percent_Identity=31.0861423220974, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI193206261, Length=296, Percent_Identity=31.7567567567568, Blast_Score=103, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6325345, Length=305, Percent_Identity=33.1147540983607, Blast_Score=161, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6320498, Length=234, Percent_Identity=32.0512820512821, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI17647949, Length=267, Percent_Identity=31.4606741573034, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24641198, Length=226, Percent_Identity=33.6283185840708, Blast_Score=108, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 44481; Mature: 44350

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWFFGRKKKKEQKVEQEPASQVQSESISTTVNKDSSSETHSESQSTIASQAAVEKPVQA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VETNQIEEPTSSTEGASTSEVKTETQTSSAPDNGLDEAERYDRGLERSRKSFGQKLSALF
HHHCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TNFSGVDEDFYDDLEETLIEADVGFDTALEISEEVRDEIEFEHVSDPDQISQLIVRRLVA
HCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCHHCCCCHHHHHHHHHHHHHH
LYTRNGSAEDNHLVFSKEGPTVFLFVGVNGVGKTTSIGKMAARFKGRGRKVLLAACDTFR
HHHCCCCCCCCEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEEECCHHH
AGAIQQLQEWGKRDGVDVVAGKEQSDPASVAFEAVKKAKEENYDLLLVDTAGRLQNKVNL
HHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHH
MNELDKIKRVISREIPDAPQETLLVLDSTTGQNALTQAKAFLETTNVTGIILTKLDGTAK
HHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCC
GGIVLAIRNQLHLAVKYVGLGETVDDLSPFNPEQYVSGLFKGLMED
CCEEEEEECCEEEEEEEECCCCCHHHCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AWFFGRKKKKEQKVEQEPASQVQSESISTTVNKDSSSETHSESQSTIASQAAVEKPVQA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VETNQIEEPTSSTEGASTSEVKTETQTSSAPDNGLDEAERYDRGLERSRKSFGQKLSALF
HHHCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TNFSGVDEDFYDDLEETLIEADVGFDTALEISEEVRDEIEFEHVSDPDQISQLIVRRLVA
HCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCHHCCCCHHHHHHHHHHHHHH
LYTRNGSAEDNHLVFSKEGPTVFLFVGVNGVGKTTSIGKMAARFKGRGRKVLLAACDTFR
HHHCCCCCCCCEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEEECCHHH
AGAIQQLQEWGKRDGVDVVAGKEQSDPASVAFEAVKKAKEENYDLLLVDTAGRLQNKVNL
HHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHH
MNELDKIKRVISREIPDAPQETLLVLDSTTGQNALTQAKAFLETTNVTGIILTKLDGTAK
HHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCC
GGIVLAIRNQLHLAVKYVGLGETVDDLSPFNPEQYVSGLFKGLMED
CCEEEEEECCEEEEEEEECCCCCHHHCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584053; 9384377; 8654983 [H]