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The map label for this gene is bglH [H]

Identifier: 116492376

GI number: 116492376

Start: 636245

End: 637699

Strand: Direct

Name: bglH [H]

Synonym: PEPE_0581

Alternate gene names: 116492376

Gene position: 636245-637699 (Clockwise)

Preceding gene: 116492375

Following gene: 116492377

Centisome position: 34.72

GC content: 35.6

Gene sequence:

>1455_bases
ATGAAAAATCAATATGCGTATTTTCCAAAGGACTTTTTATGGGGAGGAGCACAAGCTGCGAGCCAAGCGGACGGAGCATA
TCTAGAAAATGGAAAAGGATTAAACTCTTCAGACGTACAACCTTTTTTGAAAGGGCTATCAAATGAAGAAATTCAAGAAA
TGGAGTCAGAAGGAATGACTCTAGAAAAAGTTAGGGAGAATATCAATGACAAAAGTCATTATTATCCCAAACGTTATGGT
ATTGATTTTTATCACACTTATGAATCTGATATTGATTTACTTAGTGAGATGGGATTCAAAACGTTCCGTACCTCATTAGA
CTGGTCACGTATTTTCCCAAATGGTGATGATGAAGAACCTAATGTAGAGGCTCTTGAACATTATTCAAAGATGATTGACT
ACATGGTTAAAAAAGGTATTGAGCCAATTATTACTATGAATCATTATGAGACACCTATTAATATTACGCTGAAGTATGGC
GGATGGCCCAATAAAAAAGTTATTCCAATGTTTGAAAAATTTGGAAAAATCTTGCTAGACTGGTTCGGTGAAAAGGTGAA
GTATTGGATTGTGGTTAACCAAATTAACATGGTTCAGGTTGAACCTTGGCTTTCAGTCGGAGTAGCAATTGACCAATATG
AAAACCTTGATGAAGCTTTATATCAATCAACACATAACCAAATGGTAGCGGCAGCCTGGATCAAAAAGTATGCTAAATCT
TTGAATATTCCAAATCTCAATATTGGAACCATGGTTGCGGATGGGACAGTATTTCCCGCAACTGGCAAACCCAGTGACGT
TGTATTAGCTATGCAACAAAATCGAATGCAGTATATGTTCACAGACGTCCAATTTAGAGGAGCATATCCAAAATTTGCTC
GAAATTATTTTGAAGAACATGAAGTTCATCTAGATATCACGCTTCAAGAGATGGAATTAATCAAAAACAATCCAATGGAT
TTCTTGGGGATTTCATATTACTATTCAAAAATGGTTGATGCAACTAAGAATAGATATGAAGCGAATGATACACTTCCTAA
TCCCTATTTAAAGACTTCTCCATGGGGCTGGGCTATTGATCCAGAAGGATTTTACAATACTCTTTCACAATATGCGGATC
GATATGGTAAACCAATTATTATCGCCGAAAATGGAATTGGAATGTACGATGAACTTACAGAAGATAAAAAGGTACACGAT
GAGTATCGTACAGAATATTTATCACAACATATTGAACAATTAGGACGAGCTATCCATGATGGAGCGAATGTTATTGCTTA
TTGTGCTTGGGGTCCTATTGATATCGTGTCTTGTTCCTCACAACAAATGTCTAAACGTTATGGTTTTGTATATGTAGATT
TAGATGATGAAGGAAATGGATCCGGAGTAAGATATAAAAAGGACAGTTTTTACTGGTATCAGAAAGTTATTTCTACTAAT
GGAGATGAAATTTAA

Upstream 100 bases:

>100_bases
CCCAAGACACAGTAATGACGATTATGAGTGAATATAATCTTGCTAAACGATTAATCAATATTTTTGAAAAAAAAGAAGAG
AAATTTAGGGGGAGTAAATA

Downstream 100 bases:

>100_bases
TAAAATGATAAGTTGTTCTTTAAGAACAGCTTATTTTATAACTTGAGGATATAAAAATGTCTGAAAAAAAAGAGCGAAAG
ATGCTGAATCTTCTAAAAAG

Product: Beta-glucosidase/6-phospho-beta- glucosidase/beta-galactosidase

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MKNQYAYFPKDFLWGGAQAASQADGAYLENGKGLNSSDVQPFLKGLSNEEIQEMESEGMTLEKVRENINDKSHYYPKRYG
IDFYHTYESDIDLLSEMGFKTFRTSLDWSRIFPNGDDEEPNVEALEHYSKMIDYMVKKGIEPIITMNHYETPINITLKYG
GWPNKKVIPMFEKFGKILLDWFGEKVKYWIVVNQINMVQVEPWLSVGVAIDQYENLDEALYQSTHNQMVAAAWIKKYAKS
LNIPNLNIGTMVADGTVFPATGKPSDVVLAMQQNRMQYMFTDVQFRGAYPKFARNYFEEHEVHLDITLQEMELIKNNPMD
FLGISYYYSKMVDATKNRYEANDTLPNPYLKTSPWGWAIDPEGFYNTLSQYADRYGKPIIIAENGIGMYDELTEDKKVHD
EYRTEYLSQHIEQLGRAIHDGANVIAYCAWGPIDIVSCSSQQMSKRYGFVYVDLDDEGNGSGVRYKKDSFYWYQKVISTN
GDEI

Sequences:

>Translated_484_residues
MKNQYAYFPKDFLWGGAQAASQADGAYLENGKGLNSSDVQPFLKGLSNEEIQEMESEGMTLEKVRENINDKSHYYPKRYG
IDFYHTYESDIDLLSEMGFKTFRTSLDWSRIFPNGDDEEPNVEALEHYSKMIDYMVKKGIEPIITMNHYETPINITLKYG
GWPNKKVIPMFEKFGKILLDWFGEKVKYWIVVNQINMVQVEPWLSVGVAIDQYENLDEALYQSTHNQMVAAAWIKKYAKS
LNIPNLNIGTMVADGTVFPATGKPSDVVLAMQQNRMQYMFTDVQFRGAYPKFARNYFEEHEVHLDITLQEMELIKNNPMD
FLGISYYYSKMVDATKNRYEANDTLPNPYLKTSPWGWAIDPEGFYNTLSQYADRYGKPIIIAENGIGMYDELTEDKKVHD
EYRTEYLSQHIEQLGRAIHDGANVIAYCAWGPIDIVSCSSQQMSKRYGFVYVDLDDEGNGSGVRYKKDSFYWYQKVISTN
GDEI
>Mature_484_residues
MKNQYAYFPKDFLWGGAQAASQADGAYLENGKGLNSSDVQPFLKGLSNEEIQEMESEGMTLEKVRENINDKSHYYPKRYG
IDFYHTYESDIDLLSEMGFKTFRTSLDWSRIFPNGDDEEPNVEALEHYSKMIDYMVKKGIEPIITMNHYETPINITLKYG
GWPNKKVIPMFEKFGKILLDWFGEKVKYWIVVNQINMVQVEPWLSVGVAIDQYENLDEALYQSTHNQMVAAAWIKKYAKS
LNIPNLNIGTMVADGTVFPATGKPSDVVLAMQQNRMQYMFTDVQFRGAYPKFARNYFEEHEVHLDITLQEMELIKNNPMD
FLGISYYYSKMVDATKNRYEANDTLPNPYLKTSPWGWAIDPEGFYNTLSQYADRYGKPIIIAENGIGMYDELTEDKKVHD
EYRTEYLSQHIEQLGRAIHDGANVIAYCAWGPIDIVSCSSQQMSKRYGFVYVDLDDEGNGSGVRYKKDSFYWYQKVISTN
GDEI

Specific function: Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. Bgl

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI110681710, Length=507, Percent_Identity=27.2189349112426, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI13273313, Length=502, Percent_Identity=25.8964143426295, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI32481206, Length=514, Percent_Identity=25.4863813229572, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI28376633, Length=488, Percent_Identity=24.5901639344262, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI24497614, Length=483, Percent_Identity=23.6024844720497, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1789070, Length=482, Percent_Identity=40.6639004149378, Blast_Score=403, Evalue=1e-113,
Organism=Escherichia coli, GI2367270, Length=479, Percent_Identity=42.3799582463466, Blast_Score=399, Evalue=1e-112,
Organism=Escherichia coli, GI2367174, Length=487, Percent_Identity=39.8357289527721, Blast_Score=389, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI17552856, Length=492, Percent_Identity=27.2357723577236, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17539390, Length=493, Percent_Identity=26.369168356998, Blast_Score=148, Evalue=6e-36,
Organism=Drosophila melanogaster, GI21356577, Length=492, Percent_Identity=25.8130081300813, Blast_Score=138, Evalue=8e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 55947; Mature: 55947

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNQYAYFPKDFLWGGAQAASQADGAYLENGKGLNSSDVQPFLKGLSNEEIQEMESEGMT
CCCCCCCCCHHHHCCCCHHHCCCCCCEECCCCCCCCCHHHHHHHCCCHHHHHHHHHCCCC
LEKVRENINDKSHYYPKRYGIDFYHTYESDIDLLSEMGFKTFRTSLDWSRIFPNGDDEEP
HHHHHHCCCCCCCCCCHHCCCEEEEECHHHHHHHHHCCHHHHHHCCCHHHCCCCCCCCCC
NVEALEHYSKMIDYMVKKGIEPIITMNHYETPINITLKYGGWPNKKVIPMFEKFGKILLD
CHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHH
WFGEKVKYWIVVNQINMVQVEPWLSVGVAIDQYENLDEALYQSTHNQMVAAAWIKKYAKS
HHCCCEEEEEEEECCCEEEECCHHHHCEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
LNIPNLNIGTMVADGTVFPATGKPSDVVLAMQQNRMQYMFTDVQFRGAYPKFARNYFEEH
CCCCCCCCCEEEECCEEECCCCCCCCEEEEEHHCCEEEEEEEEEECCCCHHHHHHHHHHC
EVHLDITLQEMELIKNNPMDFLGISYYYSKMVDATKNRYEANDTLPNPYLKTSPWGWAID
EEEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
PEGFYNTLSQYADRYGKPIIIAENGIGMYDELTEDKKVHDEYRTEYLSQHIEQLGRAIHD
CHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GANVIAYCAWGPIDIVSCSSQQMSKRYGFVYVDLDDEGNGSGVRYKKDSFYWYQKVISTN
CCCEEEEEECCCEEEEECCHHHHHHHCCEEEEEECCCCCCCCEEEECCCHHHHHHHHHCC
GDEI
CCCC
>Mature Secondary Structure
MKNQYAYFPKDFLWGGAQAASQADGAYLENGKGLNSSDVQPFLKGLSNEEIQEMESEGMT
CCCCCCCCCHHHHCCCCHHHCCCCCCEECCCCCCCCCHHHHHHHCCCHHHHHHHHHCCCC
LEKVRENINDKSHYYPKRYGIDFYHTYESDIDLLSEMGFKTFRTSLDWSRIFPNGDDEEP
HHHHHHCCCCCCCCCCHHCCCEEEEECHHHHHHHHHCCHHHHHHCCCHHHCCCCCCCCCC
NVEALEHYSKMIDYMVKKGIEPIITMNHYETPINITLKYGGWPNKKVIPMFEKFGKILLD
CHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHH
WFGEKVKYWIVVNQINMVQVEPWLSVGVAIDQYENLDEALYQSTHNQMVAAAWIKKYAKS
HHCCCEEEEEEEECCCEEEECCHHHHCEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
LNIPNLNIGTMVADGTVFPATGKPSDVVLAMQQNRMQYMFTDVQFRGAYPKFARNYFEEH
CCCCCCCCCEEEECCEEECCCCCCCCEEEEEHHCCEEEEEEEEEECCCCHHHHHHHHHHC
EVHLDITLQEMELIKNNPMDFLGISYYYSKMVDATKNRYEANDTLPNPYLKTSPWGWAID
EEEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
PEGFYNTLSQYADRYGKPIIIAENGIGMYDELTEDKKVHDEYRTEYLSQHIEQLGRAIHD
CHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GANVIAYCAWGPIDIVSCSSQQMSKRYGFVYVDLDDEGNGSGVRYKKDSFYWYQKVISTN
CCCEEEEEECCCEEEEECCHHHHHHHCCEEEEEECCCCCCCCEEEECCCHHHHHHHHHCC
GDEI
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7883710; 7704263; 9384377 [H]