Click here to switch to the map view.

The map label for this gene is asnC [H]

Identifier: 116492342

GI number: 116492342

Start: 604220

End: 605614

Strand: Direct

Name: asnC [H]

Synonym: PEPE_0547

Alternate gene names: 116492342

Gene position: 604220-605614 (Clockwise)

Preceding gene: 116492341

Following gene: 116492345

Centisome position: 32.97

GC content: 39.5

Gene sequence:

>1395_bases
ATGGAAAACACATTAGTTAAAACACTCTACTCTCAAGCAGAACATGATGCTGACGTAGAAGTGGAAGTAACTGGCTGGTT
AAAAACCATCCGTTCTTCAAAGAAAATTAGCTTTTTAGAAATTAACGATGGTTCTTACATCAAGAATGTTCAAGTTATCA
TGGACAACAATGCCCTTGAAAACTCTGAAGAAATTCGTAAGGCAGCAATCTATTCTACAATCAAAGTTGTAGGTAAAGTG
GCTGATACACCTAAGGCTAAGCAACCATTTGAAATTCAAGCTAGTTCAATCACAATTTTAGGTAGCTCAAACAGTGACTA
CCCATTGCAAAAGAAGGAACATACTCCTGAATTCTTGCGGGAACAAGCTCATTTACGTCCTCGGACAAACACTTTCTATG
CTGTTTTCCGGATTCGTTCATTGGTTTCTTTTGCTGTTCATCAATTCTTACAAAGCAACAACTTTGTTTACGTTAACACA
CCGATCATCACCAGCAGTGATACTGAAGGTGCCGGTGAAATGTTCAAGGTAACAACGCTAGATTTGAACAACTTACCTAA
GAACGAAGCTGGGGAAGTAGATTCAAGCAAGGACTTCTTCAAACAACCTACCAACTTAACCGTTAGTGGACAATTGAATG
CAGAAGCTTTTGCTTTGGCTTTTAGAAATGTTTATACATTCGGCCCAGCCTTTAGAGCTGAAAACTCACATACTACGCGT
CATGCTTCAGAATTCTGGATGATTGAACCAGAAATGGCCTTTGCTAACCTTCAAGATATTATGAATACTTCTGAAGATTT
GTTGAAGTACGTGGTTAACTATCTTTTGGAAAATGCTAAAGAAGAATTGGAATTCTTGAACGGTGCCGTTGATCCAGAAT
TAAAAGCTCGTTTGGAAGCTACTAAGGATGCTGACTTTGCCCGAGTTTCATACACAGAAGCCATCGACATCTTAATGAAT
GCCGATCAAGAGTTTGAAAACCCAGTCGAATGGGGCATTGATTTACAAACTGAACACGAAAGATACTTAAGTGAAAAGGT
ATATCAAAAACCTGTCTTCATCACGGATTATCCTAAGGACATCAAGGCCTTCTACATGCGTGAAAATGAAGACCACAAGA
CTGTAGCTGCAGTTGACCTTTTGGTTCCTGGTATCGGTGAATTAATCGGTGGTAGTCAACGTGAAGAACGTCTCGACAAG
ATCAACGAAAAGATTGCCGAATTCCATCTCGATCCTAAGGAATACGAATGGTACGCTGAACTAAGAAAATACGGAGAAAC
TGAACATTCTGGTTTCGGAATTGGATTCGAAAGATTACTTATGTACGTAACCGGAATCGAAAACATCCGCGATGTAATTC
CATTCCCTCGTACACCAGGAAATGCTAGTTTCTAA

Upstream 100 bases:

>100_bases
AATTTTGGGTGGTACCGCGAAAGTCCTTCGTCCCTTCTGGGAGGAGGACTTTTTTATTTGTACCGGACTTTTTACGAGGA
TAAGAATGGAGGATTTATTC

Downstream 100 bases:

>100_bases
TTTAATCGTTAAAATAAAAAGCACCCAATCACAGATTGGATGCTTTTTTATTTAACCATCTTATAATTTAAAAAATAAGT
GTTGCGTAGCAGTGCACAAT

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MENTLVKTLYSQAEHDADVEVEVTGWLKTIRSSKKISFLEINDGSYIKNVQVIMDNNALENSEEIRKAAIYSTIKVVGKV
ADTPKAKQPFEIQASSITILGSSNSDYPLQKKEHTPEFLREQAHLRPRTNTFYAVFRIRSLVSFAVHQFLQSNNFVYVNT
PIITSSDTEGAGEMFKVTTLDLNNLPKNEAGEVDSSKDFFKQPTNLTVSGQLNAEAFALAFRNVYTFGPAFRAENSHTTR
HASEFWMIEPEMAFANLQDIMNTSEDLLKYVVNYLLENAKEELEFLNGAVDPELKARLEATKDADFARVSYTEAIDILMN
ADQEFENPVEWGIDLQTEHERYLSEKVYQKPVFITDYPKDIKAFYMRENEDHKTVAAVDLLVPGIGELIGGSQREERLDK
INEKIAEFHLDPKEYEWYAELRKYGETEHSGFGIGFERLLMYVTGIENIRDVIPFPRTPGNASF

Sequences:

>Translated_464_residues
MENTLVKTLYSQAEHDADVEVEVTGWLKTIRSSKKISFLEINDGSYIKNVQVIMDNNALENSEEIRKAAIYSTIKVVGKV
ADTPKAKQPFEIQASSITILGSSNSDYPLQKKEHTPEFLREQAHLRPRTNTFYAVFRIRSLVSFAVHQFLQSNNFVYVNT
PIITSSDTEGAGEMFKVTTLDLNNLPKNEAGEVDSSKDFFKQPTNLTVSGQLNAEAFALAFRNVYTFGPAFRAENSHTTR
HASEFWMIEPEMAFANLQDIMNTSEDLLKYVVNYLLENAKEELEFLNGAVDPELKARLEATKDADFARVSYTEAIDILMN
ADQEFENPVEWGIDLQTEHERYLSEKVYQKPVFITDYPKDIKAFYMRENEDHKTVAAVDLLVPGIGELIGGSQREERLDK
INEKIAEFHLDPKEYEWYAELRKYGETEHSGFGIGFERLLMYVTGIENIRDVIPFPRTPGNASF
>Mature_464_residues
MENTLVKTLYSQAEHDADVEVEVTGWLKTIRSSKKISFLEINDGSYIKNVQVIMDNNALENSEEIRKAAIYSTIKVVGKV
ADTPKAKQPFEIQASSITILGSSNSDYPLQKKEHTPEFLREQAHLRPRTNTFYAVFRIRSLVSFAVHQFLQSNNFVYVNT
PIITSSDTEGAGEMFKVTTLDLNNLPKNEAGEVDSSKDFFKQPTNLTVSGQLNAEAFALAFRNVYTFGPAFRAENSHTTR
HASEFWMIEPEMAFANLQDIMNTSEDLLKYVVNYLLENAKEELEFLNGAVDPELKARLEATKDADFARVSYTEAIDILMN
ADQEFENPVEWGIDLQTEHERYLSEKVYQKPVFITDYPKDIKAFYMRENEDHKTVAAVDLLVPGIGELIGGSQREERLDK
INEKIAEFHLDPKEYEWYAELRKYGETEHSGFGIGFERLLMYVTGIENIRDVIPFPRTPGNASF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=455, Percent_Identity=42.4175824175824, Blast_Score=388, Evalue=1e-108,
Organism=Homo sapiens, GI4758762, Length=451, Percent_Identity=28.3813747228381, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI45439306, Length=341, Percent_Identity=30.2052785923754, Blast_Score=128, Evalue=1e-29,
Organism=Escherichia coli, GI1787161, Length=456, Percent_Identity=54.1666666666667, Blast_Score=520, Evalue=1e-149,
Organism=Caenorhabditis elegans, GI17556372, Length=426, Percent_Identity=32.6291079812207, Blast_Score=210, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI71984122, Length=458, Percent_Identity=28.3842794759825, Blast_Score=183, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17551876, Length=481, Percent_Identity=27.8586278586279, Blast_Score=140, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6319872, Length=481, Percent_Identity=38.2536382536383, Blast_Score=333, Evalue=4e-92,
Organism=Saccharomyces cerevisiae, GI6321807, Length=453, Percent_Identity=28.6975717439294, Blast_Score=198, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6323011, Length=344, Percent_Identity=30.5232558139535, Blast_Score=138, Evalue=2e-33,
Organism=Drosophila melanogaster, GI19922416, Length=453, Percent_Identity=35.9823399558499, Blast_Score=277, Evalue=1e-74,
Organism=Drosophila melanogaster, GI19921528, Length=448, Percent_Identity=26.7857142857143, Blast_Score=161, Evalue=9e-40,
Organism=Drosophila melanogaster, GI17136276, Length=472, Percent_Identity=26.4830508474576, Blast_Score=112, Evalue=4e-25,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 52917; Mature: 52917

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENTLVKTLYSQAEHDADVEVEVTGWLKTIRSSKKISFLEINDGSYIKNVQVIMDNNALE
CCCHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCEEEEEECCCCEEEEEEEEECCCCCC
NSEEIRKAAIYSTIKVVGKVADTPKAKQPFEIQASSITILGSSNSDYPLQKKEHTPEFLR
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECEEEEEECCCCCCCCCCCCCCHHHHH
EQAHLRPRTNTFYAVFRIRSLVSFAVHQFLQSNNFVYVNTPIITSSDTEGAGEMFKVTTL
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEECCCCCCCCCEEEEEEE
DLNNLPKNEAGEVDSSKDFFKQPTNLTVSGQLNAEAFALAFRNVYTFGPAFRAENSHTTR
ECCCCCCCCCCCCCCCHHHHCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
HASEFWMIEPEMAFANLQDIMNTSEDLLKYVVNYLLENAKEELEFLNGAVDPELKARLEA
CCCCEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
TKDADFARVSYTEAIDILMNADQEFENPVEWGIDLQTEHERYLSEKVYQKPVFITDYPKD
CCCCCHHHHHHHHHHHHHHCCCHHHCCHHHHCCCCCHHHHHHHHHHHHHCCEEEECCCHH
IKAFYMRENEDHKTVAAVDLLVPGIGELIGGSQREERLDKINEKIAEFHLDPKEYEWYAE
HHHHHCCCCCCCCHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LRKYGETEHSGFGIGFERLLMYVTGIENIRDVIPFPRTPGNASF
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MENTLVKTLYSQAEHDADVEVEVTGWLKTIRSSKKISFLEINDGSYIKNVQVIMDNNALE
CCCHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCEEEEEECCCCEEEEEEEEECCCCCC
NSEEIRKAAIYSTIKVVGKVADTPKAKQPFEIQASSITILGSSNSDYPLQKKEHTPEFLR
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECEEEEEECCCCCCCCCCCCCCHHHHH
EQAHLRPRTNTFYAVFRIRSLVSFAVHQFLQSNNFVYVNTPIITSSDTEGAGEMFKVTTL
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEECCCCCCCCCEEEEEEE
DLNNLPKNEAGEVDSSKDFFKQPTNLTVSGQLNAEAFALAFRNVYTFGPAFRAENSHTTR
ECCCCCCCCCCCCCCCHHHHCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
HASEFWMIEPEMAFANLQDIMNTSEDLLKYVVNYLLENAKEELEFLNGAVDPELKARLEA
CCCCEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
TKDADFARVSYTEAIDILMNADQEFENPVEWGIDLQTEHERYLSEKVYQKPVFITDYPKD
CCCCCHHHHHHHHHHHHHHCCCHHHCCHHHHCCCCCHHHHHHHHHHHHHCCEEEECCCHH
IKAFYMRENEDHKTVAAVDLLVPGIGELIGGSQREERLDKINEKIAEFHLDPKEYEWYAE
HHHHHCCCCCCCCHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LRKYGETEHSGFGIGFERLLMYVTGIENIRDVIPFPRTPGNASF
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA