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The map label for this gene is puuP [H]

Identifier: 116492295

GI number: 116492295

Start: 547219

End: 549540

Strand: Reverse

Name: puuP [H]

Synonym: PEPE_0495

Alternate gene names: 116492295

Gene position: 549540-547219 (Counterclockwise)

Preceding gene: 116492296

Following gene: 116492282

Centisome position: 29.99

GC content: 35.66

Gene sequence:

>2322_bases
ATGGAAGAAAACACAAGCTATGATGAAGGACTCAAAGTTAGTCTTTCCACAAAAGATTTATTAGTTTATGGTATTACATT
CATGATCCCGGTTGCACCACTCGCATTTTATGGATCATTCCTAACCCCTGCAAATGGTATGGTTGCTTTAGCTTACTTTG
TAGGAATGGTGGCAATGCTCTTTACAGGATTTAGTTATGCTACGATGTCGAGGAGATACCCATTTTCAGGATCAGTTTAT
ACGTACGTTCAACAAGGAACTAATGCCGGTTTAGGATTTATTGGTGGTTGGGGGATTACACTTGATTACTTTTTGATTCC
CACCATCACCTATTTAATCAGTAAATCATTCGGTGAATCGTTATTTCCGACAGTTCCTGGGTGGGCATGGATCATTATCT
TAGTGATATTTAATACTATCGTCAATATTTTAGGTGCAAACGTTGTTACTAAAATTAGTTGGGTTTTGTTTGCACTCCAA
GGAATTGTTTTAGTTGCTTTTATTATTGGCACCATTCGACTACTTCTTTCGGGTGCTATTCAACCACAAACGATTTCATT
TTATAATCCTCAACACTTCAACATACAGGGTGTTCTCCAAGCAACGGGTATTGTCATTGTTAGTTATTTAGGCTTTGATG
CCATCAGTACGCTCTCTGAAGAAGCGGAAGATCCACATCGCTCAGTAGGGAGAGCTATTATTCTTTCAATTTTATCAATT
GGTATTCTGTTTGTTGTTATTACTGTTTTGGCTGGATTTGTAGCTCCAGATTATCAAAATCTCAATCAGAATACTGCCTT
TCTCGGTATTCTTCAACGAGTTGGTGGCACATGGTTAGTTAAATTAGCAGACATTACAATTATTCTTTCATTCGGCTTCG
CCAGTGGTCAAGAAGGTCAAACCGCAGTTTCACGGATTCTTTACGCTATGGGCAGAGATGGCATTTTACCTCCTGCTTTT
GCTAAATTGCATAAGAAGTATCGAACACCAATCTTTGCCATTGTTCTAGTGGGCTTGGCTTCACTAATTCTATCACTAAC
GCTTTCACAAGATACGGTTTCTAATCTGGTTAGTTTTGGTGCCTTATTCGGATTCATTTTGTTGAATCTTTCGGTCATTT
GGAAGTTTTATGTAAAGGGAGACCACGGTTCAGTTTTTAGTAAAGAACGTGTCGAAACAAAATATTATGAAGACGATACT
AAAATTTATTTAACCTTACTAAAAAAGCAAGATATTCTGGATTTAGATTTATCTCGAGAACGGGTTAAAAAACGTGTTAT
TAGCAACATTTCAACGACTGGTAACACCAAGTATGCTGAAAAACTAATTTCTAAATATTACAGAGATTTCGACTACGTTT
TTGATATGGTTCGAGCTGAACAAGCTCTTCCATCCAAAAAAGATAACTTTTTAAAATCAATATCCGAACCTAAACCCACT
CCCAGATTTCAAATTCATAAATATGATTTAGTCAAACTCATCGATGGTCGCCTTGCGATAGTATTTAGTATCAACGATGC
TAATACAGAATACGAAGTGAGAGTTGAAAAAGGCTCCGAAAGCTGGGAACTCATTACCATTAAACAAATTGATATTGCAC
ACGTCTACCAACATTTAGATTCATTTTTATCACCAACTAAAATATCGTTATCAATCAAAGATGTTTTTTTCAAACATGAC
GTGAATTTTCTAATTGAGGAATTTCCCGATATTAATGTGGAGACCCTTTGTACTGATAGTGAGTGGTTTGATTTAGAAAA
TAAATTAGAAGGTTTGTTACTCAAATATAGTCAAATATCTAATAAACAATCACATAATATCGGCATTCGAATACAACAAA
TGCTTGATATTATTCCCGAAAAATATGTCGATGTACGTTTATCCTCCGTAGTTCCTCCCACTCTAGAAGAAATCGATCAA
CTGGAGGAACTGGATGTAGTTAAATTAAAAGATGGTAAATTTGCTACAATCGTATTTGCTCCACCTCATCCCTATTCCTG
GGATATGCACTTTGATTTTGATATTGGAGATTCTTCAACATCATGGGCCACTCCGATTACCGAAATTGCTGAAATTATAT
TTTTTCATTCTAAAAATCTACCAATCCATCTTAATAAAATGCTTACTAAAGAAGCCATCCAGAATTTACATGTCTTGGTA
CCTGACTTTGATGTTAATAAAACTCTCAGTAAAGAAGAGTTCACAAAACTTTACGACCTCATTGATCATAAATTAATGAC
TCAAGGCTTTGATACAAATGATGAACCAACTCCAATCGGATTAATGGCCGAAAACTTATTAACCGAATTTGCAGACATAT
AA

Upstream 100 bases:

>100_bases
TATAAGCAGATACTATCATTTTAAAAATAAATAGAACCCGTTAAATGATTTTTTATACTGTTTTATAAATAAAACTTATT
AAAATTTGAGAGCATATTAT

Downstream 100 bases:

>100_bases
TAGTTTTTATTAAAGTATCCTTAACCATCTAATATAAAAAAGACCAACTTCAAAAGTTGGCCCTCCTCTAAAACAGCAAA
TCAACTTGCTGTTTTTTGTA

Product: amino acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 773; Mature: 773

Protein sequence:

>773_residues
MEENTSYDEGLKVSLSTKDLLVYGITFMIPVAPLAFYGSFLTPANGMVALAYFVGMVAMLFTGFSYATMSRRYPFSGSVY
TYVQQGTNAGLGFIGGWGITLDYFLIPTITYLISKSFGESLFPTVPGWAWIIILVIFNTIVNILGANVVTKISWVLFALQ
GIVLVAFIIGTIRLLLSGAIQPQTISFYNPQHFNIQGVLQATGIVIVSYLGFDAISTLSEEAEDPHRSVGRAIILSILSI
GILFVVITVLAGFVAPDYQNLNQNTAFLGILQRVGGTWLVKLADITIILSFGFASGQEGQTAVSRILYAMGRDGILPPAF
AKLHKKYRTPIFAIVLVGLASLILSLTLSQDTVSNLVSFGALFGFILLNLSVIWKFYVKGDHGSVFSKERVETKYYEDDT
KIYLTLLKKQDILDLDLSRERVKKRVISNISTTGNTKYAEKLISKYYRDFDYVFDMVRAEQALPSKKDNFLKSISEPKPT
PRFQIHKYDLVKLIDGRLAIVFSINDANTEYEVRVEKGSESWELITIKQIDIAHVYQHLDSFLSPTKISLSIKDVFFKHD
VNFLIEEFPDINVETLCTDSEWFDLENKLEGLLLKYSQISNKQSHNIGIRIQQMLDIIPEKYVDVRLSSVVPPTLEEIDQ
LEELDVVKLKDGKFATIVFAPPHPYSWDMHFDFDIGDSSTSWATPITEIAEIIFFHSKNLPIHLNKMLTKEAIQNLHVLV
PDFDVNKTLSKEEFTKLYDLIDHKLMTQGFDTNDEPTPIGLMAENLLTEFADI

Sequences:

>Translated_773_residues
MEENTSYDEGLKVSLSTKDLLVYGITFMIPVAPLAFYGSFLTPANGMVALAYFVGMVAMLFTGFSYATMSRRYPFSGSVY
TYVQQGTNAGLGFIGGWGITLDYFLIPTITYLISKSFGESLFPTVPGWAWIIILVIFNTIVNILGANVVTKISWVLFALQ
GIVLVAFIIGTIRLLLSGAIQPQTISFYNPQHFNIQGVLQATGIVIVSYLGFDAISTLSEEAEDPHRSVGRAIILSILSI
GILFVVITVLAGFVAPDYQNLNQNTAFLGILQRVGGTWLVKLADITIILSFGFASGQEGQTAVSRILYAMGRDGILPPAF
AKLHKKYRTPIFAIVLVGLASLILSLTLSQDTVSNLVSFGALFGFILLNLSVIWKFYVKGDHGSVFSKERVETKYYEDDT
KIYLTLLKKQDILDLDLSRERVKKRVISNISTTGNTKYAEKLISKYYRDFDYVFDMVRAEQALPSKKDNFLKSISEPKPT
PRFQIHKYDLVKLIDGRLAIVFSINDANTEYEVRVEKGSESWELITIKQIDIAHVYQHLDSFLSPTKISLSIKDVFFKHD
VNFLIEEFPDINVETLCTDSEWFDLENKLEGLLLKYSQISNKQSHNIGIRIQQMLDIIPEKYVDVRLSSVVPPTLEEIDQ
LEELDVVKLKDGKFATIVFAPPHPYSWDMHFDFDIGDSSTSWATPITEIAEIIFFHSKNLPIHLNKMLTKEAIQNLHVLV
PDFDVNKTLSKEEFTKLYDLIDHKLMTQGFDTNDEPTPIGLMAENLLTEFADI
>Mature_773_residues
MEENTSYDEGLKVSLSTKDLLVYGITFMIPVAPLAFYGSFLTPANGMVALAYFVGMVAMLFTGFSYATMSRRYPFSGSVY
TYVQQGTNAGLGFIGGWGITLDYFLIPTITYLISKSFGESLFPTVPGWAWIIILVIFNTIVNILGANVVTKISWVLFALQ
GIVLVAFIIGTIRLLLSGAIQPQTISFYNPQHFNIQGVLQATGIVIVSYLGFDAISTLSEEAEDPHRSVGRAIILSILSI
GILFVVITVLAGFVAPDYQNLNQNTAFLGILQRVGGTWLVKLADITIILSFGFASGQEGQTAVSRILYAMGRDGILPPAF
AKLHKKYRTPIFAIVLVGLASLILSLTLSQDTVSNLVSFGALFGFILLNLSVIWKFYVKGDHGSVFSKERVETKYYEDDT
KIYLTLLKKQDILDLDLSRERVKKRVISNISTTGNTKYAEKLISKYYRDFDYVFDMVRAEQALPSKKDNFLKSISEPKPT
PRFQIHKYDLVKLIDGRLAIVFSINDANTEYEVRVEKGSESWELITIKQIDIAHVYQHLDSFLSPTKISLSIKDVFFKHD
VNFLIEEFPDINVETLCTDSEWFDLENKLEGLLLKYSQISNKQSHNIGIRIQQMLDIIPEKYVDVRLSSVVPPTLEEIDQ
LEELDVVKLKDGKFATIVFAPPHPYSWDMHFDFDIGDSSTSWATPITEIAEIIFFHSKNLPIHLNKMLTKEAIQNLHVLV
PDFDVNKTLSKEEFTKLYDLIDHKLMTQGFDTNDEPTPIGLMAENLLTEFADI

Specific function: Imports putrescine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI114326544, Length=184, Percent_Identity=25.5434782608696, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI114326550, Length=184, Percent_Identity=25.5434782608696, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI181337167, Length=401, Percent_Identity=22.9426433915212, Blast_Score=72, Evalue=3e-12,
Organism=Homo sapiens, GI110347453, Length=407, Percent_Identity=25.5528255528256, Blast_Score=70, Evalue=7e-12,
Organism=Homo sapiens, GI258645169, Length=463, Percent_Identity=20.5183585313175, Blast_Score=68, Evalue=4e-11,
Organism=Escherichia coli, GI87081869, Length=378, Percent_Identity=30.952380952381, Blast_Score=184, Evalue=2e-47,
Organism=Escherichia coli, GI87082023, Length=386, Percent_Identity=32.9015544041451, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI1788480, Length=386, Percent_Identity=22.279792746114, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786602, Length=324, Percent_Identity=23.1481481481481, Blast_Score=63, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17533459, Length=403, Percent_Identity=24.0694789081886, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17532491, Length=396, Percent_Identity=23.989898989899, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17531343, Length=182, Percent_Identity=26.3736263736264, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI221512776, Length=397, Percent_Identity=24.4332493702771, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24666159, Length=397, Percent_Identity=24.4332493702771, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24668806, Length=369, Percent_Identity=23.0352303523035, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21356285, Length=369, Percent_Identity=23.0352303523035, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24668802, Length=369, Percent_Identity=23.0352303523035, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI161077963, Length=344, Percent_Identity=24.7093023255814, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24667468, Length=392, Percent_Identity=21.9387755102041, Blast_Score=75, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 86879; Mature: 86879

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEENTSYDEGLKVSLSTKDLLVYGITFMIPVAPLAFYGSFLTPANGMVALAYFVGMVAML
CCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
FTGFSYATMSRRYPFSGSVYTYVQQGTNAGLGFIGGWGITLDYFLIPTITYLISKSFGES
HCCCHHHHHCCCCCCCCCEEEEEECCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCC
LFPTVPGWAWIIILVIFNTIVNILGANVVTKISWVLFALQGIVLVAFIIGTIRLLLSGAI
CCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QPQTISFYNPQHFNIQGVLQATGIVIVSYLGFDAISTLSEEAEDPHRSVGRAIILSILSI
CCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GILFVVITVLAGFVAPDYQNLNQNTAFLGILQRVGGTWLVKLADITIILSFGFASGQEGQ
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCEEEEEHHHEEEEEEECCCCCCCCH
TAVSRILYAMGRDGILPPAFAKLHKKYRTPIFAIVLVGLASLILSLTLSQDTVSNLVSFG
HHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
ALFGFILLNLSVIWKFYVKGDHGSVFSKERVETKYYEDDTKIYLTLLKKQDILDLDLSRE
HHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHEECCCCEEEEEEECCCCCCCCCCCHH
RVKKRVISNISTTGNTKYAEKLISKYYRDFDYVFDMVRAEQALPSKKDNFLKSISEPKPT
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCC
PRFQIHKYDLVKLIDGRLAIVFSINDANTEYEVRVEKGSESWELITIKQIDIAHVYQHLD
CCEEEEHHHHHHHCCCCEEEEEEECCCCCEEEEEEECCCCCEEEEEEEECHHHHHHHHHH
SFLSPTKISLSIKDVFFKHDVNFLIEEFPDINVETLCTDSEWFDLENKLEGLLLKYSQIS
HHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHCCHHHHHHHHHHHHHHHC
NKQSHNIGIRIQQMLDIIPEKYVDVRLSSVVPPTLEEIDQLEELDVVKLKDGKFATIVFA
CCCCCCCCEEHHHHHHHCCHHHHHEEHHHCCCCCHHHHHHHHCCCEEEECCCCEEEEEEE
PPHPYSWDMHFDFDIGDSSTSWATPITEIAEIIFFHSKNLPIHLNKMLTKEAIQNLHVLV
CCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCEEEE
PDFDVNKTLSKEEFTKLYDLIDHKLMTQGFDTNDEPTPIGLMAENLLTEFADI
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEENTSYDEGLKVSLSTKDLLVYGITFMIPVAPLAFYGSFLTPANGMVALAYFVGMVAML
CCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
FTGFSYATMSRRYPFSGSVYTYVQQGTNAGLGFIGGWGITLDYFLIPTITYLISKSFGES
HCCCHHHHHCCCCCCCCCEEEEEECCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCC
LFPTVPGWAWIIILVIFNTIVNILGANVVTKISWVLFALQGIVLVAFIIGTIRLLLSGAI
CCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QPQTISFYNPQHFNIQGVLQATGIVIVSYLGFDAISTLSEEAEDPHRSVGRAIILSILSI
CCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GILFVVITVLAGFVAPDYQNLNQNTAFLGILQRVGGTWLVKLADITIILSFGFASGQEGQ
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCEEEEEHHHEEEEEEECCCCCCCCH
TAVSRILYAMGRDGILPPAFAKLHKKYRTPIFAIVLVGLASLILSLTLSQDTVSNLVSFG
HHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
ALFGFILLNLSVIWKFYVKGDHGSVFSKERVETKYYEDDTKIYLTLLKKQDILDLDLSRE
HHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHEECCCCEEEEEEECCCCCCCCCCCHH
RVKKRVISNISTTGNTKYAEKLISKYYRDFDYVFDMVRAEQALPSKKDNFLKSISEPKPT
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCC
PRFQIHKYDLVKLIDGRLAIVFSINDANTEYEVRVEKGSESWELITIKQIDIAHVYQHLD
CCEEEEHHHHHHHCCCCEEEEEEECCCCCEEEEEEECCCCCEEEEEEEECHHHHHHHHHH
SFLSPTKISLSIKDVFFKHDVNFLIEEFPDINVETLCTDSEWFDLENKLEGLLLKYSQIS
HHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHCCHHHHHHHHHHHHHHHC
NKQSHNIGIRIQQMLDIIPEKYVDVRLSSVVPPTLEEIDQLEELDVVKLKDGKFATIVFA
CCCCCCCCEEHHHHHHHCCHHHHHEEHHHCCCCCHHHHHHHHCCCEEEECCCCEEEEEEE
PPHPYSWDMHFDFDIGDSSTSWATPITEIAEIIFFHSKNLPIHLNKMLTKEAIQNLHVLV
CCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCEEEE
PDFDVNKTLSKEEFTKLYDLIDHKLMTQGFDTNDEPTPIGLMAENLLTEFADI
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]