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The map label for this gene is xylR [H]

Identifier: 116491997

GI number: 116491997

Start: 219621

End: 220772

Strand: Direct

Name: xylR [H]

Synonym: PEPE_0186

Alternate gene names: 116491997

Gene position: 219621-220772 (Clockwise)

Preceding gene: 116491996

Following gene: 116491998

Centisome position: 11.99

GC content: 32.9

Gene sequence:

>1152_bases
ATGGTAATTCATAAAGAAACGATGCGATCAGCAAACGAAAAATCAGTTTTACAGAGAATTTTTACCGAAGGTCCGATTTC
AAAAAGCCAGGTAGCTAGGGATGTTAGCCTAAACAAAGTGACTGTGTCACAAATAATCAATAAATTTATTTCAAGTAGAT
TGGTTGTTGAAGCGGGATCTGGAGATAGCACACAGCAAGGCGGTAGAAAACCTGAGCTGGTACAGATTAATTCGAAATAT
GGATATGTGGTTTGCATCGATCTTGGATATCAAGAATTATCAGTACTTTCTATGTCAATTAATGGTCAAAAATTAGATAG
TAGACATACAATTTTTGGAAATGACGATATAAATATAGCTATTGAAAAAATATATGAAATATTGGTCGAATTTCAGGAAA
TGCATAAAGAACGATTGCTAGGACTTTTAGTATCGATCCATGGAATCGTTCATAAAAATCAAGTTATTTATTCTCCTTTT
TGGAATATGAAACAAATTGATTTGGCTGATACGTTGTCAAAAAAATTTGATATACCAGTAATTTTAGAAAATGAGGCTAA
TTTGACAGCCACTTTTGAGCGCGATTATAGCGTAAATGAAATTCAGAATGCAGTCAGCATTAGTATGCATAAAGGTATTG
GTGCAGGAATAATTATTGATGGCGAATTGTATCGAGGACGAAAAGGTGAAGCAGGCGAGATTGGTCAAACGGTTGCTTTT
GAAAGTGAAAATCAGTCACTTGAGAAAAGCAACAAAATTGAAGACGTTTGTTCTCCCCAAGTAATTTTAGCGCGGATTAA
AAATGCTAAAAAATTGGAATATATAAATTGGCAACTAGTTCGACAAATGTTTGATGATAAAGATCAAGAAACGTTAGAAA
TTTTAAAAGAGTTTGAGAATAATGTTGCAAAGATAATTAATAACGTAATTGTGTCATTTGATCCGGACGTGTTAGTTGTT
AATGCATACATTTTCAAAGAATTTCCAGAAATTTTAGAACGAATAAGTAATGGTTTTGCACATGTTTCGGTTAGAAATAC
ACCGATTGTTTTAAGTGAGAACGTTAAAAATGCAAGTCTTTATGGCGGCTGTGCCCAAATGATTCGAACTATTTTAGGTG
TTTCGAAACTTAAATTACAATACAAAAAATAG

Upstream 100 bases:

>100_bases
ACAAGGTAGATGGTGTTGAAGACAAGATGCAAGCAGATCTTGCAGCAAAACATCAAAAAGAAAATGAAGAAGAATAATAT
AAGTAATTAGGGAGAGCAAC

Downstream 100 bases:

>100_bases
AAGAGGTTTTTATAATGAGTGAATATTACGATTTTAACAAGATGGAATATATTGGTAACCAAAAAGGTCTAAAGGCTGGA
GATGGTTTTCACTACTACAA

Product: transcriptional regulator/sugar kinase, xylose operon regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MVIHKETMRSANEKSVLQRIFTEGPISKSQVARDVSLNKVTVSQIINKFISSRLVVEAGSGDSTQQGGRKPELVQINSKY
GYVVCIDLGYQELSVLSMSINGQKLDSRHTIFGNDDINIAIEKIYEILVEFQEMHKERLLGLLVSIHGIVHKNQVIYSPF
WNMKQIDLADTLSKKFDIPVILENEANLTATFERDYSVNEIQNAVSISMHKGIGAGIIIDGELYRGRKGEAGEIGQTVAF
ESENQSLEKSNKIEDVCSPQVILARIKNAKKLEYINWQLVRQMFDDKDQETLEILKEFENNVAKIINNVIVSFDPDVLVV
NAYIFKEFPEILERISNGFAHVSVRNTPIVLSENVKNASLYGGCAQMIRTILGVSKLKLQYKK

Sequences:

>Translated_383_residues
MVIHKETMRSANEKSVLQRIFTEGPISKSQVARDVSLNKVTVSQIINKFISSRLVVEAGSGDSTQQGGRKPELVQINSKY
GYVVCIDLGYQELSVLSMSINGQKLDSRHTIFGNDDINIAIEKIYEILVEFQEMHKERLLGLLVSIHGIVHKNQVIYSPF
WNMKQIDLADTLSKKFDIPVILENEANLTATFERDYSVNEIQNAVSISMHKGIGAGIIIDGELYRGRKGEAGEIGQTVAF
ESENQSLEKSNKIEDVCSPQVILARIKNAKKLEYINWQLVRQMFDDKDQETLEILKEFENNVAKIINNVIVSFDPDVLVV
NAYIFKEFPEILERISNGFAHVSVRNTPIVLSENVKNASLYGGCAQMIRTILGVSKLKLQYKK
>Mature_383_residues
MVIHKETMRSANEKSVLQRIFTEGPISKSQVARDVSLNKVTVSQIINKFISSRLVVEAGSGDSTQQGGRKPELVQINSKY
GYVVCIDLGYQELSVLSMSINGQKLDSRHTIFGNDDINIAIEKIYEILVEFQEMHKERLLGLLVSIHGIVHKNQVIYSPF
WNMKQIDLADTLSKKFDIPVILENEANLTATFERDYSVNEIQNAVSISMHKGIGAGIIIDGELYRGRKGEAGEIGQTVAF
ESENQSLEKSNKIEDVCSPQVILARIKNAKKLEYINWQLVRQMFDDKDQETLEILKEFENNVAKIINNVIVSFDPDVLVV
NAYIFKEFPEILERISNGFAHVSVRNTPIVLSENVKNASLYGGCAQMIRTILGVSKLKLQYKK

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Escherichia coli, GI1786891, Length=387, Percent_Identity=21.1886304909561, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 43154; Mature: 43154

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIHKETMRSANEKSVLQRIFTEGPISKSQVARDVSLNKVTVSQIINKFISSRLVVEAGS
CCCCHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEECC
GDSTQQGGRKPELVQINSKYGYVVCIDLGYQELSVLSMSINGQKLDSRHTIFGNDDINIA
CCCHHCCCCCCCEEEEECCCCEEEEEECCCCEEEEEEEECCCCCCCCCCEEECCCCCHHH
IEKIYEILVEFQEMHKERLLGLLVSIHGIVHKNQVIYSPFWNMKQIDLADTLSKKFDIPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEECHHHHHHHHCCCCE
ILENEANLTATFERDYSVNEIQNAVSISMHKGIGAGIIIDGELYRGRKGEAGEIGQTVAF
EEECCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCEEEE
ESENQSLEKSNKIEDVCSPQVILARIKNAKKLEYINWQLVRQMFDDKDQETLEILKEFEN
CCCCCHHHHHCCHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
NVAKIINNVIVSFDPDVLVVNAYIFKEFPEILERISNGFAHVSVRNTPIVLSENVKNASL
HHHHHHHHHHEECCCCEEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCCCCCHH
YGGCAQMIRTILGVSKLKLQYKK
HHHHHHHHHHHHCHHHHEEEECC
>Mature Secondary Structure
MVIHKETMRSANEKSVLQRIFTEGPISKSQVARDVSLNKVTVSQIINKFISSRLVVEAGS
CCCCHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEECC
GDSTQQGGRKPELVQINSKYGYVVCIDLGYQELSVLSMSINGQKLDSRHTIFGNDDINIA
CCCHHCCCCCCCEEEEECCCCEEEEEECCCCEEEEEEEECCCCCCCCCCEEECCCCCHHH
IEKIYEILVEFQEMHKERLLGLLVSIHGIVHKNQVIYSPFWNMKQIDLADTLSKKFDIPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEECHHHHHHHHCCCCE
ILENEANLTATFERDYSVNEIQNAVSISMHKGIGAGIIIDGELYRGRKGEAGEIGQTVAF
EEECCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCEEEE
ESENQSLEKSNKIEDVCSPQVILARIKNAKKLEYINWQLVRQMFDDKDQETLEILKEFEN
CCCCCHHHHHCCHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
NVAKIINNVIVSFDPDVLVVNAYIFKEFPEILERISNGFAHVSVRNTPIVLSENVKNASL
HHHHHHHHHHEECCCCEEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCCCCCHH
YGGCAQMIRTILGVSKLKLQYKK
HHHHHHHHHHHHCHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1660563 [H]