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The map label for this gene is frlR [H]

Identifier: 116491990

GI number: 116491990

Start: 207980

End: 208672

Strand: Direct

Name: frlR [H]

Synonym: PEPE_0176

Alternate gene names: 116491990

Gene position: 207980-208672 (Clockwise)

Preceding gene: 116491989

Following gene: 116491991

Centisome position: 11.35

GC content: 30.88

Gene sequence:

>693_bases
ATGACATTATTTAAAGATATATACAAAGATCTTGATAACAAAATAAAAATGGGACTCTATAAGAAGGGCAGCGCATTACC
AAATGAAGGAGAACTTCAACTGATTTATGGAGTAAGTAGGACAACTATCAGGAACGCCGTCGATCAGCTAGTTTTAGAAG
GTAAAGTAATACGAAAAAGAGGGATAGGATTATTTGTATCTCCAAAGGTGACTAAGCAAAACATTTTAAATATGACGGGA
ATAATTAAACCAACGTATTTAAAATCAGAAGAAAAGATAAAAATTAAAGATGCCTATTTACGTAAAGCTGGAGCCTATTA
TGCACAGATTTTTAATATTAGCCCTGACGTACTTGTGTACTATATCACTTTATTAGCTTTTTCAGATGAAGAAAAAACAT
ATGAAAAAATAATTATGCCGTTAGACTTATTTCCTGCATTTGATCCTGAAATCTTGAAAGTAACTTCAATTATTGAAGCG
ATTAATACAGGGACATCGGATGTTCAGGATGTTTATCAAGACTTTCAATTAGTTGAAGTGAATGAAGAAGATAGTAAATA
TTTAAGTATAGAATCTGGAAGCCCAGTATTTAAAATCACCAACACATTTAGCGATAACGAAGAAAAAAATATCGCAGTGG
AATATAAATTGCAAAATGCGCTAACTACTAAATATAAAATTGATTTCGATTAA

Upstream 100 bases:

>100_bases
GATAAAGCAGTAGAACATACAGCTCAATTTTTACCAGCTAATAAAATTAAATATCATTTTAAAGCAAAAAATATTTTTGA
TTATCAAGAGGATGATGACG

Downstream 100 bases:

>100_bases
ATTGGAGGATATAGAAATGATAAAACTTCTTAGAGTAGATCATCGATTATTACATGGACAGGTGGCAGTTTCTTGGTTTA
ATGGTTTAGACGCCAACACG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MTLFKDIYKDLDNKIKMGLYKKGSALPNEGELQLIYGVSRTTIRNAVDQLVLEGKVIRKRGIGLFVSPKVTKQNILNMTG
IIKPTYLKSEEKIKIKDAYLRKAGAYYAQIFNISPDVLVYYITLLAFSDEEKTYEKIIMPLDLFPAFDPEILKVTSIIEA
INTGTSDVQDVYQDFQLVEVNEEDSKYLSIESGSPVFKITNTFSDNEEKNIAVEYKLQNALTTKYKIDFD

Sequences:

>Translated_230_residues
MTLFKDIYKDLDNKIKMGLYKKGSALPNEGELQLIYGVSRTTIRNAVDQLVLEGKVIRKRGIGLFVSPKVTKQNILNMTG
IIKPTYLKSEEKIKIKDAYLRKAGAYYAQIFNISPDVLVYYITLLAFSDEEKTYEKIIMPLDLFPAFDPEILKVTSIIEA
INTGTSDVQDVYQDFQLVEVNEEDSKYLSIESGSPVFKITNTFSDNEEKNIAVEYKLQNALTTKYKIDFD
>Mature_229_residues
TLFKDIYKDLDNKIKMGLYKKGSALPNEGELQLIYGVSRTTIRNAVDQLVLEGKVIRKRGIGLFVSPKVTKQNILNMTGI
IKPTYLKSEEKIKIKDAYLRKAGAYYAQIFNISPDVLVYYITLLAFSDEEKTYEKIIMPLDLFPAFDPEILKVTSIIEAI
NTGTSDVQDVYQDFQLVEVNEEDSKYLSIESGSPVFKITNTFSDNEEKNIAVEYKLQNALTTKYKIDFD

Specific function: May regulate the transcription of the frlABCD operon [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082252, Length=217, Percent_Identity=26.2672811059908, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 26243; Mature: 26111

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLFKDIYKDLDNKIKMGLYKKGSALPNEGELQLIYGVSRTTIRNAVDQLVLEGKVIRKR
CCHHHHHHHHHHHHHEECEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCHHHHHC
GIGLFVSPKVTKQNILNMTGIIKPTYLKSEEKIKIKDAYLRKAGAYYAQIFNISPDVLVY
CCEEEECCCCCHHHHHHHHCCCCCCEECCCCCEEHHHHHHHHHCCEEEEEECCCHHHHHH
YITLLAFSDEEKTYEKIIMPLDLFPAFDPEILKVTSIIEAINTGTSDVQDVYQDFQLVEV
HHHHHHCCCCHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEEE
NEEDSKYLSIESGSPVFKITNTFSDNEEKNIAVEYKLQNALTTKYKIDFD
CCCCCEEEEEECCCCEEEEECCCCCCCCCCEEEEEEECCCCEEEEEEECC
>Mature Secondary Structure 
TLFKDIYKDLDNKIKMGLYKKGSALPNEGELQLIYGVSRTTIRNAVDQLVLEGKVIRKR
CHHHHHHHHHHHHHEECEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCHHHHHC
GIGLFVSPKVTKQNILNMTGIIKPTYLKSEEKIKIKDAYLRKAGAYYAQIFNISPDVLVY
CCEEEECCCCCHHHHHHHHCCCCCCEECCCCCEEHHHHHHHHHCCEEEEEECCCHHHHHH
YITLLAFSDEEKTYEKIIMPLDLFPAFDPEILKVTSIIEAINTGTSDVQDVYQDFQLVEV
HHHHHHCCCCHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEEE
NEEDSKYLSIESGSPVFKITNTFSDNEEKNIAVEYKLQNALTTKYKIDFD
CCCCCEEEEEECCCCEEEEECCCCCCCCCCEEEEEEECCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]