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The map label for this gene is araR [H]

Identifier: 116491971

GI number: 116491971

Start: 186391

End: 187467

Strand: Direct

Name: araR [H]

Synonym: PEPE_0157

Alternate gene names: 116491971

Gene position: 186391-187467 (Clockwise)

Preceding gene: 116491970

Following gene: 116491976

Centisome position: 10.17

GC content: 36.86

Gene sequence:

>1077_bases
ATGGAAAATAAATACGACGTTGTAAAACGAGATATTAAAGAAAAAATATTATCTGGACATTATTCTATTAATGATAGGTT
GCCAACCGAAGCCAGCTTAATGGAACAGTATGGCGTTAGCAGATATACAATCAGACGAGCGATTGGTGATCTTGAAACGG
ATCATTACGTTTACCGTATTCAAGGCGGTGGAATGTTTGTAGATGATTGGCAAAAATATATAAATAAACCCATCGAAGGA
AAAATGATTGGGGTAATTTCAACGCATATAGCGGATTATATTTTTCCAAACATTATTACCGGGATTGACCGCTACGTTTC
TGCTGAAGGCTATTCGATTTTGATTAGTAACACCCAGAACGATCCGCAGAAAGAACGTAAAGGAATTAAAAAAATGATGG
AAATTGGCTTATCAGGCTTGATTATTGAACCGACACAAAGTGCTCTTGGAAATCCTAATCGAGACTTATACGATAAACTT
AAAGAGACGGGATTACCCACGGTATTCATTAATGCACACTACCCTGAGTTAGATTTCCCGTACTTGGAAGTTAACGATTA
TGAGGCGGAACGCCAAGTCACCAACAAGTTAATTGGGATGGGTCACGAAAAGATACTGGGAATTTTTAAAATTGATGATA
CACAGGGTGTCCATCGAATGAAGGGTTACATTAGTGCATACCAGGAACATCGAGATTTAGTGATGTTAAGTGAAATGGTG
ATGTACCAATCATCTGATAACATGCACAATGTGTTTACTCGAATCGAAAGCATTTTAGCACGTCCAGATCGGCCAACAGC
AATTATCTGCTATCATGATCAAATTGCTATTCGAGTGATAGATTTAGTCCGCTCGATGGGATTAAAGATTCCAGAAGATA
TTTCAATTTTTGGATTTGATAATTATAAGTTGGCTAAATATATTTCTCCCAAACTAAGTACAGTTGAACATCCGAAGGAA
ACAATGGGTAGAGACGCTGCCAAGACGATTTTTGATATCATCGAAGGTCGCCCCTATGAAAAGAATAAAGTTTATGATCC
AGAATTAATCATTAGGGAATCAATTAAAAAGATATAA

Upstream 100 bases:

>100_bases
TTTTAATCATTGTACTAAAAGCTAACTTAATCTGCGATAAAGCAATTATGAAATGTTACTATTTATATATGAAAAGTATT
TTAACAGAGTAGGTATAGAT

Downstream 100 bases:

>100_bases
TTTGTTGAAAAATAAAATGGAATGGCAGACTAAATTCACTGGTGTTGTATTAGTTTGGTAAATAAAGTTTTTAGAACTCA
TCATTCATATATCGGATAAG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MENKYDVVKRDIKEKILSGHYSINDRLPTEASLMEQYGVSRYTIRRAIGDLETDHYVYRIQGGGMFVDDWQKYINKPIEG
KMIGVISTHIADYIFPNIITGIDRYVSAEGYSILISNTQNDPQKERKGIKKMMEIGLSGLIIEPTQSALGNPNRDLYDKL
KETGLPTVFINAHYPELDFPYLEVNDYEAERQVTNKLIGMGHEKILGIFKIDDTQGVHRMKGYISAYQEHRDLVMLSEMV
MYQSSDNMHNVFTRIESILARPDRPTAIICYHDQIAIRVIDLVRSMGLKIPEDISIFGFDNYKLAKYISPKLSTVEHPKE
TMGRDAAKTIFDIIEGRPYEKNKVYDPELIIRESIKKI

Sequences:

>Translated_358_residues
MENKYDVVKRDIKEKILSGHYSINDRLPTEASLMEQYGVSRYTIRRAIGDLETDHYVYRIQGGGMFVDDWQKYINKPIEG
KMIGVISTHIADYIFPNIITGIDRYVSAEGYSILISNTQNDPQKERKGIKKMMEIGLSGLIIEPTQSALGNPNRDLYDKL
KETGLPTVFINAHYPELDFPYLEVNDYEAERQVTNKLIGMGHEKILGIFKIDDTQGVHRMKGYISAYQEHRDLVMLSEMV
MYQSSDNMHNVFTRIESILARPDRPTAIICYHDQIAIRVIDLVRSMGLKIPEDISIFGFDNYKLAKYISPKLSTVEHPKE
TMGRDAAKTIFDIIEGRPYEKNKVYDPELIIRESIKKI
>Mature_358_residues
MENKYDVVKRDIKEKILSGHYSINDRLPTEASLMEQYGVSRYTIRRAIGDLETDHYVYRIQGGGMFVDDWQKYINKPIEG
KMIGVISTHIADYIFPNIITGIDRYVSAEGYSILISNTQNDPQKERKGIKKMMEIGLSGLIIEPTQSALGNPNRDLYDKL
KETGLPTVFINAHYPELDFPYLEVNDYEAERQVTNKLIGMGHEKILGIFKIDDTQGVHRMKGYISAYQEHRDLVMLSEMV
MYQSSDNMHNVFTRIESILARPDRPTAIICYHDQIAIRVIDLVRSMGLKIPEDISIFGFDNYKLAKYISPKLSTVEHPKE
TMGRDAAKTIFDIIEGRPYEKNKVYDPELIIRESIKKI

Specific function: Transcriptional repressor of the arabinose utilization genes. Also regulates its own expression. Binds to two sequences within the promoters of the araABDLMNPQ-abfA operon and the araE gene, and to one sequence in the araR promoter [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=285, Percent_Identity=28.7719298245614, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1787948, Length=279, Percent_Identity=26.1648745519713, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1790194, Length=245, Percent_Identity=24.8979591836735, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789202, Length=281, Percent_Identity=25.6227758007117, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI48994940, Length=260, Percent_Identity=26.1538461538462, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1788474, Length=279, Percent_Identity=23.2974910394265, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1790715, Length=266, Percent_Identity=25.5639097744361, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789068, Length=262, Percent_Identity=20.6106870229008, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR001761
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 41242; Mature: 41242

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENKYDVVKRDIKEKILSGHYSINDRLPTEASLMEQYGVSRYTIRRAIGDLETDHYVYRI
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEE
QGGGMFVDDWQKYINKPIEGKMIGVISTHIADYIFPNIITGIDRYVSAEGYSILISNTQN
CCCCEEHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
DPQKERKGIKKMMEIGLSGLIIEPTQSALGNPNRDLYDKLKETGLPTVFINAHYPELDFP
CHHHHHHHHHHHHHCCCCCEEECCCHHHCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCC
YLEVNDYEAERQVTNKLIGMGHEKILGIFKIDDTQGVHRMKGYISAYQEHRDLVMLSEMV
EEECCCCHHHHHHHHHHHCCCHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MYQSSDNMHNVFTRIESILARPDRPTAIICYHDQIAIRVIDLVRSMGLKIPEDISIFGFD
HHCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCEEEECC
NYKLAKYISPKLSTVEHPKETMGRDAAKTIFDIIEGRPYEKNKVYDPELIIRESIKKI
CCCHHHHCCCCHHHHCCCHHHHCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MENKYDVVKRDIKEKILSGHYSINDRLPTEASLMEQYGVSRYTIRRAIGDLETDHYVYRI
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEE
QGGGMFVDDWQKYINKPIEGKMIGVISTHIADYIFPNIITGIDRYVSAEGYSILISNTQN
CCCCEEHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
DPQKERKGIKKMMEIGLSGLIIEPTQSALGNPNRDLYDKLKETGLPTVFINAHYPELDFP
CHHHHHHHHHHHHHCCCCCEEECCCHHHCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCC
YLEVNDYEAERQVTNKLIGMGHEKILGIFKIDDTQGVHRMKGYISAYQEHRDLVMLSEMV
EEECCCCHHHHHHHHHHHCCCHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MYQSSDNMHNVFTRIESILARPDRPTAIICYHDQIAIRVIDLVRSMGLKIPEDISIFGFD
HHCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCEEEECC
NYKLAKYISPKLSTVEHPKETMGRDAAKTIFDIIEGRPYEKNKVYDPELIIRESIKKI
CCCHHHHCCCCHHHHCCCHHHHCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9045819; 9384377; 10417639; 11418559 [H]