Click here to switch to the map view.

The map label for this gene is dapH

Identifier: 116491949

GI number: 116491949

Start: 159943

End: 160653

Strand: Reverse

Name: dapH

Synonym: PEPE_0135

Alternate gene names: 116491949

Gene position: 160653-159943 (Counterclockwise)

Preceding gene: 116491950

Following gene: 116491948

Centisome position: 8.77

GC content: 43.46

Gene sequence:

>711_bases
ATGAGTAATCTTGACACCCAGTCCATTATTAACACCATTTCAAACTCCAAAAAGCAGACCCCCGTTCGAGTGTTTATTGC
CGGAGAAAAACTATATCAATTACAAATACCGAATGAAATTGAAGCTTTTATTTCACCAACTTCTGGAACTCTTTTTGGTG
AATGGAAATACGTTAAAGCACTATTAGAATCATCTTCTCAAATCACACACTATCGAGTCGAAAACGATAGTCGAAATTCT
GCAGTTCCTCTTCTGGACAAAAAGGAAGTCAATGCCCGAATTGAGCCAGGCGCTATCATCCGTGATCAAGTTTTAATTGG
CAATAATGCAGTTATCATGATGGGCGCTATTATTAATATCGGCGCTGAGATTGGGGCCGAAACAATGATCGATATGGGCG
TCGTCCTTGGTGGGCGGGCTCTAGTTGGTCGACATTGTCATATTGGTGCAGGTGCCGTCTTAGCTGGCGTAATTGAACCA
GCTTCCGCTCAACCCGTTCAAATTGATGATCATGTTTTGATTGGAGCCAATGCCGTTGTGGTTGAAGGCGTTCATGTTGG
AACCGGTGCTGTTGTTGCTGCCGGAGCAGTAGTTACCAAAGACGTTCCTGCACATACAGTAGTTGCTGGGGTACCAGCTC
AAATTATTAAACGGGTTGATAATACAACTTCCCAGAAAACAGCGCTTGAAGACGGACTACGTAACCTATAA

Upstream 100 bases:

>100_bases
TTGCTGAAAATAGCCAAGCTCAATTAGTTATTCAAAGAGAAACATACGCAGATATGATACAAAATGATTTAGATTATTGA
AAATTGAAAGGGGAATTACT

Downstream 100 bases:

>100_bases
GGAAGTGTTTAAAATGACCATTGAACCATTAAATTTAGTTCGAATAAGGCGGCAGTTTCACGAATCACCGGAATTAGCCC
TAAAAGAATTCCAGACCCAC

Product: tetrahydrodipicolinate N-succinyltransferase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-acetyltransferase; THP acetyltransferase; Tetrahydropicolinate acetylase

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MSNLDTQSIINTISNSKKQTPVRVFIAGEKLYQLQIPNEIEAFISPTSGTLFGEWKYVKALLESSSQITHYRVENDSRNS
AVPLLDKKEVNARIEPGAIIRDQVLIGNNAVIMMGAIINIGAEIGAETMIDMGVVLGGRALVGRHCHIGAGAVLAGVIEP
ASAQPVQIDDHVLIGANAVVVEGVHVGTGAVVAAGAVVTKDVPAHTVVAGVPAQIIKRVDNTTSQKTALEDGLRNL

Sequences:

>Translated_236_residues
MSNLDTQSIINTISNSKKQTPVRVFIAGEKLYQLQIPNEIEAFISPTSGTLFGEWKYVKALLESSSQITHYRVENDSRNS
AVPLLDKKEVNARIEPGAIIRDQVLIGNNAVIMMGAIINIGAEIGAETMIDMGVVLGGRALVGRHCHIGAGAVLAGVIEP
ASAQPVQIDDHVLIGANAVVVEGVHVGTGAVVAAGAVVTKDVPAHTVVAGVPAQIIKRVDNTTSQKTALEDGLRNL
>Mature_235_residues
SNLDTQSIINTISNSKKQTPVRVFIAGEKLYQLQIPNEIEAFISPTSGTLFGEWKYVKALLESSSQITHYRVENDSRNSA
VPLLDKKEVNARIEPGAIIRDQVLIGNNAVIMMGAIINIGAEIGAETMIDMGVVLGGRALVGRHCHIGAGAVLAGVIEPA
SAQPVQIDDHVLIGANAVVVEGVHVGTGAVVAAGAVVTKDVPAHTVVAGVPAQIIKRVDNTTSQKTALEDGLRNL

Specific function: Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. DapH subfamily

Homologues:

Organism=Escherichia coli, GI1786362, Length=171, Percent_Identity=28.6549707602339, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): DAPH_PEDPA (Q03HT0)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_803684.1
- ProteinModelPortal:   Q03HT0
- SMR:   Q03HT0
- STRING:   Q03HT0
- GeneID:   4417133
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_0135
- NMPDR:   fig|278197.10.peg.119
- eggNOG:   COG2171
- HOGENOM:   HBG704071
- OMA:   KNAVIMM
- BioCyc:   PPEN278197:PEPE_0135-MONOMER
- HAMAP:   MF_01691
- InterPro:   IPR013710
- InterPro:   IPR018357
- InterPro:   IPR019873
- InterPro:   IPR011004
- TIGRFAMs:   TIGR03532

Pfam domain/function: PF08503 DapD_N; SSF51161 Trimer_LpxA_like

EC number: =2.3.1.89

Molecular weight: Translated: 24824; Mature: 24693

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLDTQSIINTISNSKKQTPVRVFIAGEKLYQLQIPNEIEAFISPTSGTLFGEWKYVKA
CCCCCHHHHHHHHHCCCCCCCEEEEEECCEEEEEECCCHHHEEECCCCCCEEEHHHHHHH
LLESSSQITHYRVENDSRNSAVPLLDKKEVNARIEPGAIIRDQVLIGNNAVIMMGAIINI
HHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEECEEEECCCEEEEEEHHHHC
GAEIGAETMIDMGVVLGGRALVGRHCHIGAGAVLAGVIEPASAQPVQIDDHVLIGANAVV
CHHCCHHHHHHHHHHCCCCCCCCCCEECCCCHHHHHHCCCCCCCCEEECCEEEECCCEEE
VEGVHVGTGAVVAAGAVVTKDVPAHTVVAGVPAQIIKRVDNTTSQKTALEDGLRNL
EEEEEECCCHHHHCCEEEECCCCCHHEEECCHHHHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SNLDTQSIINTISNSKKQTPVRVFIAGEKLYQLQIPNEIEAFISPTSGTLFGEWKYVKA
CCCCHHHHHHHHHCCCCCCCEEEEEECCEEEEEECCCHHHEEECCCCCCEEEHHHHHHH
LLESSSQITHYRVENDSRNSAVPLLDKKEVNARIEPGAIIRDQVLIGNNAVIMMGAIINI
HHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEECEEEECCCEEEEEEHHHHC
GAEIGAETMIDMGVVLGGRALVGRHCHIGAGAVLAGVIEPASAQPVQIDDHVLIGANAVV
CHHCCHHHHHHHHHHCCCCCCCCCCEECCCCHHHHHHCCCCCCCCEEECCEEEECCCEEE
VEGVHVGTGAVVAAGAVVTKDVPAHTVVAGVPAQIIKRVDNTTSQKTALEDGLRNL
EEEEEECCCHHHHCCEEEECCCCCHHEEECCHHHHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA