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The map label for this gene is chbC [H]

Identifier: 116491909

GI number: 116491909

Start: 100382

End: 101677

Strand: Direct

Name: chbC [H]

Synonym: PEPE_0091

Alternate gene names: 116491909

Gene position: 100382-101677 (Clockwise)

Preceding gene: 116491908

Following gene: 116491910

Centisome position: 5.48

GC content: 37.96

Gene sequence:

>1296_bases
ATGTGGGTAAGAAGAGAACAAATTATTCGAAAAATAATACGGCTTCAACAAAATGAGTTATACCAATTAGTGCAAAAAAG
TTTAAATTTATTATTCCCATTTGTTCTTATCGGTAGTATCAGCCAACTAATTCAAATCACTATGTTAAATCGAAATAGTT
TATTGCCAACAATTTTTGGGTTTTCGTCGTGGCTAAGTCGGTATCGATTCATAGAAATTATTTTTGATCATTTAACGAGT
TTAACATTAGGAATAGTAGCTGCTTTAGCTGCATTTAGTATGGCACATTATACAGCCAAACGGTATCAGCGTGATGAAAA
ATTAGCGAGTATAACGGGATTAATTGCTTATTTAATCCTTACGGTTCGTTATACAAATAATGGTGAGTTAGCTTTTGGCC
AAGATATGCTTGGGATGGGAGGTTTGTTTTTAGGTTTTTTGGTAGGCTATCTGGTTGGACTAAGTTTTAAGCATTTGGCA
AATAGCCAGCAGCAGGATAAATCTTCTTCAGGAGTAACATGGAATCGTGCGTTAGATTCATTACGAGCAATTATAATTGT
GCTGGTTGTGGCGATTTGCTTTAGTATTTTATTAAATTGGTTGGCGATTTCGGTTTTACCAGATCAAGTTATTCTAAGAT
TACAATCACTAAAGGCTAACCAAACTTCGTTGCTATTTTCTGTAGCAATCGTACTATTGGCTGGCATAATGACTTTTTTC
GGGTTGACCAGTATGCCAATACTGGCACATTTTGGACGTAATGGCGTCGCAATGACTGCGAATTTAAACTATGCCCTTAT
ACATCACACGATTTGGGGAGTACCGTATCCTTTTTCATTAGGGACGTTATATGAATCTTTTGGCGCGATTGGGGGAACGG
GAAGTACGCTCTCATTAGTGATTGCAATTTTCTTGTTCAGTAATCAACGTGATCAACAGCTGATTGGCCGATGGTCGTTG
CTGCCAGTATTATTTAACTTTAATAGTGCGATATTAGTGGGTGTTCCAGTTTTAGGAAATGGTCTATATATTATTCCATT
TCTATTAGTTCCACTAGTTAACGTAGGAATCGCTGCAAGCGCCATTGCTTTACATTTAATGCCTGCTGTAGTTTATCAAG
TGCCGTTGGGAACTCCCAGTCTTTTGCAGGCCCTTATTGGAACCAATGGGAATTGGGTAACCTTATTGGTTATGGCACTT
AACGTAGGAATCGGCGTTTGGCTGTATCGACCATTTGTGAAATTATCCAACCGACTTAATATTCAGGGAGATGGTCTAGA
TGCCACGGAACGTTAA

Upstream 100 bases:

>100_bases
GGTTAGATATAAATAATAGCAACGCGGTGTGCAATTCGATAATGATTCAACTAGAATAAAGATAATAGTAGGAGAGATTA
GTTTAAAGAAGGAAAATCTA

Downstream 100 bases:

>100_bases
AAAATGGAGTATTATATTTTTAATTGCGAGTTTGGTAGGAATTGGAATATTGGCTTGGCCATCAATTCAGTGGATGCATA
AAAATGTGACCGCCATTTCT

Product: cellobiose-specific PTS system IIC component

Products: protein histidine; sugar phosphate

Alternate protein names: EIIC-Chb; PTS system N,N'-diacetylchitobiose-specific EIIC component [H]

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MWVRREQIIRKIIRLQQNELYQLVQKSLNLLFPFVLIGSISQLIQITMLNRNSLLPTIFGFSSWLSRYRFIEIIFDHLTS
LTLGIVAALAAFSMAHYTAKRYQRDEKLASITGLIAYLILTVRYTNNGELAFGQDMLGMGGLFLGFLVGYLVGLSFKHLA
NSQQQDKSSSGVTWNRALDSLRAIIIVLVVAICFSILLNWLAISVLPDQVILRLQSLKANQTSLLFSVAIVLLAGIMTFF
GLTSMPILAHFGRNGVAMTANLNYALIHHTIWGVPYPFSLGTLYESFGAIGGTGSTLSLVIAIFLFSNQRDQQLIGRWSL
LPVLFNFNSAILVGVPVLGNGLYIIPFLLVPLVNVGIAASAIALHLMPAVVYQVPLGTPSLLQALIGTNGNWVTLLVMAL
NVGIGVWLYRPFVKLSNRLNIQGDGLDATER

Sequences:

>Translated_431_residues
MWVRREQIIRKIIRLQQNELYQLVQKSLNLLFPFVLIGSISQLIQITMLNRNSLLPTIFGFSSWLSRYRFIEIIFDHLTS
LTLGIVAALAAFSMAHYTAKRYQRDEKLASITGLIAYLILTVRYTNNGELAFGQDMLGMGGLFLGFLVGYLVGLSFKHLA
NSQQQDKSSSGVTWNRALDSLRAIIIVLVVAICFSILLNWLAISVLPDQVILRLQSLKANQTSLLFSVAIVLLAGIMTFF
GLTSMPILAHFGRNGVAMTANLNYALIHHTIWGVPYPFSLGTLYESFGAIGGTGSTLSLVIAIFLFSNQRDQQLIGRWSL
LPVLFNFNSAILVGVPVLGNGLYIIPFLLVPLVNVGIAASAIALHLMPAVVYQVPLGTPSLLQALIGTNGNWVTLLVMAL
NVGIGVWLYRPFVKLSNRLNIQGDGLDATER
>Mature_431_residues
MWVRREQIIRKIIRLQQNELYQLVQKSLNLLFPFVLIGSISQLIQITMLNRNSLLPTIFGFSSWLSRYRFIEIIFDHLTS
LTLGIVAALAAFSMAHYTAKRYQRDEKLASITGLIAYLILTVRYTNNGELAFGQDMLGMGGLFLGFLVGYLVGLSFKHLA
NSQQQDKSSSGVTWNRALDSLRAIIIVLVVAICFSILLNWLAISVLPDQVILRLQSLKANQTSLLFSVAIVLLAGIMTFF
GLTSMPILAHFGRNGVAMTANLNYALIHHTIWGVPYPFSLGTLYESFGAIGGTGSTLSLVIAIFLFSNQRDQQLIGRWSL
LPVLFNFNSAILVGVPVLGNGLYIIPFLLVPLVNVGIAASAIALHLMPAVVYQVPLGTPSLLQALIGTNGNWVTLLVMAL
NVGIGVWLYRPFVKLSNRLNIQGDGLDATER

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=368, Percent_Identity=26.6304347826087, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: 2.7.1.69

Molecular weight: Translated: 47497; Mature: 47497

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWVRREQIIRKIIRLQQNELYQLVQKSLNLLFPFVLIGSISQLIQITMLNRNSLLPTIFG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
FSSWLSRYRFIEIIFDHLTSLTLGIVAALAAFSMAHYTAKRYQRDEKLASITGLIAYLIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVRYTNNGELAFGQDMLGMGGLFLGFLVGYLVGLSFKHLANSQQQDKSSSGVTWNRALDS
HEEECCCCCEEECCHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHCCCCCCCCHHHHHHH
LRAIIIVLVVAICFSILLNWLAISVLPDQVILRLQSLKANQTSLLFSVAIVLLAGIMTFF
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
GLTSMPILAHFGRNGVAMTANLNYALIHHTIWGVPYPFSLGTLYESFGAIGGTGSTLSLV
HHHCCHHHHHCCCCCEEEEECCCCEEEHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHHHH
IAIFLFSNQRDQQLIGRWSLLPVLFNFNSAILVGVPVLGNGLYIIPFLLVPLVNVGIAAS
HHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEECCHHCCCHHHHHHHHHHHHHHHHHHH
AIALHLMPAVVYQVPLGTPSLLQALIGTNGNWVTLLVMALNVGIGVWLYRPFVKLSNRLN
HHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
IQGDGLDATER
CCCCCCCCCCC
>Mature Secondary Structure
MWVRREQIIRKIIRLQQNELYQLVQKSLNLLFPFVLIGSISQLIQITMLNRNSLLPTIFG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
FSSWLSRYRFIEIIFDHLTSLTLGIVAALAAFSMAHYTAKRYQRDEKLASITGLIAYLIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVRYTNNGELAFGQDMLGMGGLFLGFLVGYLVGLSFKHLANSQQQDKSSSGVTWNRALDS
HEEECCCCCEEECCHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHCCCCCCCCHHHHHHH
LRAIIIVLVVAICFSILLNWLAISVLPDQVILRLQSLKANQTSLLFSVAIVLLAGIMTFF
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
GLTSMPILAHFGRNGVAMTANLNYALIHHTIWGVPYPFSLGTLYESFGAIGGTGSTLSLV
HHHCCHHHHHCCCCCEEEEECCCCEEEHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHHHH
IAIFLFSNQRDQQLIGRWSLLPVLFNFNSAILVGVPVLGNGLYIIPFLLVPLVNVGIAAS
HHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEECCHHCCCHHHHHHHHHHHHHHHHHHH
AIALHLMPAVVYQVPLGTPSLLQALIGTNGNWVTLLVMALNVGIGVWLYRPFVKLSNRLN
HHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
IQGDGLDATER
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2179047; 9097039; 9278503; 2092358; 9405618; 10913117 [H]