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The map label for this gene is zosA [H]

Identifier: 116491908

GI number: 116491908

Start: 98313

End: 100124

Strand: Direct

Name: zosA [H]

Synonym: PEPE_0090

Alternate gene names: 116491908

Gene position: 98313-100124 (Clockwise)

Preceding gene: 116491906

Following gene: 116491909

Centisome position: 5.37

GC content: 43.87

Gene sequence:

>1812_bases
ATGAGAAAATTGAGTCATAAACAAAGCTTGATGGTAATTATTGCGATTGCACTTTTGGCGGTAATCTTACAATTCGTCTT
GGGTCAAGCTTGGTTAGCCCAAATTCTGGTTTCCTTGGTGGGAGCCGTGATGGCGATGACCATGTTTATTGAGATGATTG
GGACTTTGAGGTCGGGTAAATATGGGGTCGATTTATTAGCTATTTTAGCGGTGGTTTCGAGCCTTTTATTTAGTGAGTAC
TGGGCAGCCATGGTGATTTTAGTTATGTTAACTGGTGGGGATGCCTTAGAAGACTATGCTTCCAAGAAAGCCAATACTGA
ACTCAAAGCCCTTTTAGATAATTCACCGCAAGTGGCTCATCGGCTCCATGGTGAAAAACTAGAAGATATTGCTGTTAACC
AAGTACAAGTAGATGATAAGTTGGTGATTAAACCTGGGGAATTAGTTCCGGTTGATGGGTTTATCGTTGAAGGGAGTTCA
AACTTTGATGAATCTTCTTTAACAGGAGAATCACAGCCAGTAAATAAGGACTTTAACGATGAACTTATGTCTGGTTCAGT
CAATGGTGATGCTGTGGTAACCATGCAAGCTAGTCAGGTGGCCGCCAATAGTAAGTATCAACAATTAATTAAGTTGGTTA
AGAAAGCCGAAGCAACCCCGGCCCGTTTTGTGCGGATGGCAGACCGTTATGCGGTACCTTTTACCATCGTGGCAATCGCA
ATTGCGGTGGTGGCCGCAGTAATTTCTAAGAGCCCTAGCCGAATCGCGCAAGTTTTGGTGGTGGCTTCGCCTTGTCCTTT
AATCTTAGCGGCTCCAGTGGCGATGGTTTCGGGGATGAGTCGGGCTTCTCGCAATGGGATCGTGGTTAAGACGGGGGATG
TTCTAGAAAAATTATCTACGGCTAAAACGGTCGCCTTTGATAAGACTGGAACATTAACTAATGGGCATTTGATGGTGGCG
GAGATTTTGCCACATCAAGAAGTTTCCCAAACAGAATTGCTCCAAATCGCTGCTAGTGTGGAAACTATCTCCTCGCATGT
ATTGGCGCGCTCCTTAGTAACTTACGCGATAGATAAAGGTCTGGAAATGTTAAGTGTTAGTGACGCCCAGGAAATTACGG
CGAATGGAGTACAGGCCTTGATTCAAGGAAAATTAGTCAAGGTTGGTAAGCGTAAATTTGTAACGGGAGATCCTTTAATC
CAGAGTCAAACCCATACCGCTATCTATGTCAGTCGGGACGATCAATACTTAGGTTGTATCACTTTTACCGACTACCTCAG
ACCAGAAGCTAGCCAGACCATGGTTCAGTTGCATCACTTAGGCGTTAAGAAATTAATGATGTTAAGTGGTGACCAAGTCA
AAACAGCTCAAAAAATCGGTCAAGAAGTTGGAATCGATGATGTCCAAGCTGAATTGCTACCAGAAGATAAAATTGCTGCA
TTAAAAGCTCTCACTCCGGAAGAAAAGCCGGTGGTGATGGTCGGGGACGGTGTTAATGATGCCCCTAGCTTGGTAACTGC
CGATGTAGGAATTGCCATGGGAGCTCATGGATCGTCTGCTGCCAGTGAATCGGCGGATTTGGTTATCTTAAAAGATGACT
TAGCTAAGGTAGCTAAAGCAGTTGTAATCGCAAAAGATACCATTCGAGTTGCTCGGCAAGCCGTTTTAATCGGGATCTTT
ATCTGTACAGCGTTAATGTTGATCGCCGCTTTTGGAATTATTCCGGCATTTATTGGAGCGATGTTCCAAGAAGTGATTGA
TACAGTTTCAATTTTATGGGCGTTGAGGGCACGTTATTCTAATGAAAAATAA

Upstream 100 bases:

>100_bases
ACAGTTCTGACCAGAAATAAGGCATGAATAAGCAGTATAATTGAGATAAAGCAATATAGATATCATGATTGAATTACATT
GAGGGGAATGATAAATCAAT

Downstream 100 bases:

>100_bases
GATAAGTTATAAGAAGTAGGAAAGTATACTATTTTCGAACCTATAGAGAGCACTTTAATACCCGGGTTGTTAAAGCAATA
ATCCAAGCATTTAAATATAT

Product: cation transport ATPase

Products: NA

Alternate protein names: Zn(2+)-translocating P-type ATPase [H]

Number of amino acids: Translated: 603; Mature: 603

Protein sequence:

>603_residues
MRKLSHKQSLMVIIAIALLAVILQFVLGQAWLAQILVSLVGAVMAMTMFIEMIGTLRSGKYGVDLLAILAVVSSLLFSEY
WAAMVILVMLTGGDALEDYASKKANTELKALLDNSPQVAHRLHGEKLEDIAVNQVQVDDKLVIKPGELVPVDGFIVEGSS
NFDESSLTGESQPVNKDFNDELMSGSVNGDAVVTMQASQVAANSKYQQLIKLVKKAEATPARFVRMADRYAVPFTIVAIA
IAVVAAVISKSPSRIAQVLVVASPCPLILAAPVAMVSGMSRASRNGIVVKTGDVLEKLSTAKTVAFDKTGTLTNGHLMVA
EILPHQEVSQTELLQIAASVETISSHVLARSLVTYAIDKGLEMLSVSDAQEITANGVQALIQGKLVKVGKRKFVTGDPLI
QSQTHTAIYVSRDDQYLGCITFTDYLRPEASQTMVQLHHLGVKKLMMLSGDQVKTAQKIGQEVGIDDVQAELLPEDKIAA
LKALTPEEKPVVMVGDGVNDAPSLVTADVGIAMGAHGSSAASESADLVILKDDLAKVAKAVVIAKDTIRVARQAVLIGIF
ICTALMLIAAFGIIPAFIGAMFQEVIDTVSILWALRARYSNEK

Sequences:

>Translated_603_residues
MRKLSHKQSLMVIIAIALLAVILQFVLGQAWLAQILVSLVGAVMAMTMFIEMIGTLRSGKYGVDLLAILAVVSSLLFSEY
WAAMVILVMLTGGDALEDYASKKANTELKALLDNSPQVAHRLHGEKLEDIAVNQVQVDDKLVIKPGELVPVDGFIVEGSS
NFDESSLTGESQPVNKDFNDELMSGSVNGDAVVTMQASQVAANSKYQQLIKLVKKAEATPARFVRMADRYAVPFTIVAIA
IAVVAAVISKSPSRIAQVLVVASPCPLILAAPVAMVSGMSRASRNGIVVKTGDVLEKLSTAKTVAFDKTGTLTNGHLMVA
EILPHQEVSQTELLQIAASVETISSHVLARSLVTYAIDKGLEMLSVSDAQEITANGVQALIQGKLVKVGKRKFVTGDPLI
QSQTHTAIYVSRDDQYLGCITFTDYLRPEASQTMVQLHHLGVKKLMMLSGDQVKTAQKIGQEVGIDDVQAELLPEDKIAA
LKALTPEEKPVVMVGDGVNDAPSLVTADVGIAMGAHGSSAASESADLVILKDDLAKVAKAVVIAKDTIRVARQAVLIGIF
ICTALMLIAAFGIIPAFIGAMFQEVIDTVSILWALRARYSNEK
>Mature_603_residues
MRKLSHKQSLMVIIAIALLAVILQFVLGQAWLAQILVSLVGAVMAMTMFIEMIGTLRSGKYGVDLLAILAVVSSLLFSEY
WAAMVILVMLTGGDALEDYASKKANTELKALLDNSPQVAHRLHGEKLEDIAVNQVQVDDKLVIKPGELVPVDGFIVEGSS
NFDESSLTGESQPVNKDFNDELMSGSVNGDAVVTMQASQVAANSKYQQLIKLVKKAEATPARFVRMADRYAVPFTIVAIA
IAVVAAVISKSPSRIAQVLVVASPCPLILAAPVAMVSGMSRASRNGIVVKTGDVLEKLSTAKTVAFDKTGTLTNGHLMVA
EILPHQEVSQTELLQIAASVETISSHVLARSLVTYAIDKGLEMLSVSDAQEITANGVQALIQGKLVKVGKRKFVTGDPLI
QSQTHTAIYVSRDDQYLGCITFTDYLRPEASQTMVQLHHLGVKKLMMLSGDQVKTAQKIGQEVGIDDVQAELLPEDKIAA
LKALTPEEKPVVMVGDGVNDAPSLVTADVGIAMGAHGSSAASESADLVILKDDLAKVAKAVVIAKDTIRVARQAVLIGIF
ICTALMLIAAFGIIPAFIGAMFQEVIDTVSILWALRARYSNEK

Specific function: Couples the hydrolysis of ATP with the transport of zinc into the cell [H]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily [H]

Homologues:

Organism=Homo sapiens, GI55743071, Length=655, Percent_Identity=28.3969465648855, Blast_Score=210, Evalue=3e-54,
Organism=Homo sapiens, GI55743073, Length=515, Percent_Identity=30.2912621359223, Blast_Score=196, Evalue=5e-50,
Organism=Homo sapiens, GI115529486, Length=381, Percent_Identity=29.6587926509186, Blast_Score=130, Evalue=5e-30,
Organism=Homo sapiens, GI28373113, Length=160, Percent_Identity=30, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI28373105, Length=218, Percent_Identity=27.0642201834862, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI28373103, Length=160, Percent_Identity=30, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI28373107, Length=160, Percent_Identity=30, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI28373115, Length=160, Percent_Identity=30, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI28373111, Length=160, Percent_Identity=30, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI28373109, Length=160, Percent_Identity=30, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI118498343, Length=100, Percent_Identity=38, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1789879, Length=616, Percent_Identity=31.8181818181818, Blast_Score=254, Evalue=1e-68,
Organism=Escherichia coli, GI1786691, Length=528, Percent_Identity=33.5227272727273, Blast_Score=251, Evalue=8e-68,
Organism=Escherichia coli, GI1786914, Length=540, Percent_Identity=25.9259259259259, Blast_Score=135, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17556548, Length=618, Percent_Identity=30.42071197411, Blast_Score=180, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI71997275, Length=208, Percent_Identity=29.8076923076923, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71997262, Length=208, Percent_Identity=29.8076923076923, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71997269, Length=153, Percent_Identity=32.6797385620915, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17554158, Length=202, Percent_Identity=25.7425742574257, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71988506, Length=217, Percent_Identity=25.3456221198157, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193210130, Length=202, Percent_Identity=25.7425742574257, Blast_Score=70, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6320475, Length=514, Percent_Identity=29.3774319066148, Blast_Score=194, Evalue=3e-50,
Organism=Saccharomyces cerevisiae, GI6319772, Length=658, Percent_Identity=25.0759878419453, Blast_Score=158, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6325221, Length=531, Percent_Identity=23.728813559322, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320245, Length=163, Percent_Identity=34.3558282208589, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320243, Length=163, Percent_Identity=34.3558282208589, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320244, Length=163, Percent_Identity=34.3558282208589, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6321271, Length=218, Percent_Identity=28.4403669724771, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI221329854, Length=383, Percent_Identity=30.5483028720627, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24668708, Length=153, Percent_Identity=30.0653594771242, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI281366617, Length=153, Percent_Identity=30.0653594771242, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24668704, Length=153, Percent_Identity=30.0653594771242, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI161085803, Length=153, Percent_Identity=30.0653594771242, Blast_Score=73, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24668696, Length=167, Percent_Identity=29.3413173652695, Blast_Score=73, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR001366
- InterPro:   IPR006404
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR000150 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00702 Hydrolase [H]

EC number: =3.6.3.5 [H]

Molecular weight: Translated: 64364; Mature: 64364

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS00154 ATPASE_E1_E2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLSHKQSLMVIIAIALLAVILQFVLGQAWLAQILVSLVGAVMAMTMFIEMIGTLRSGK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
YGVDLLAILAVVSSLLFSEYWAAMVILVMLTGGDALEDYASKKANTELKALLDNSPQVAH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHCCCHHHHH
RLHGEKLEDIAVNQVQVDDKLVIKPGELVPVDGFIVEGSSNFDESSLTGESQPVNKDFND
HHCCCHHHHHHCCEEEECCEEEECCCCEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCH
ELMSGSVNGDAVVTMQASQVAANSKYQQLIKLVKKAEATPARFVRMADRYAVPFTIVAIA
HHHCCCCCCCEEEEEEHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHH
IAVVAAVISKSPSRIAQVLVVASPCPLILAAPVAMVSGMSRASRNGIVVKTGDVLEKLST
HHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHH
AKTVAFDKTGTLTNGHLMVAEILPHQEVSQTELLQIAASVETISSHVLARSLVTYAIDKG
HHHEEECCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LEMLSVSDAQEITANGVQALIQGKLVKVGKRKFVTGDPLIQSQTHTAIYVSRDDQYLGCI
CHHEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEE
TFTDYLRPEASQTMVQLHHLGVKKLMMLSGDQVKTAQKIGQEVGIDDVQAELLPEDKIAA
EEHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHCCCHHHHH
LKALTPEEKPVVMVGDGVNDAPSLVTADVGIAMGAHGSSAASESADLVILKDDLAKVAKA
HHHCCCCCCCEEEECCCCCCCCCCEEEHHHHEECCCCCCCCCCCCCEEEEHHHHHHHHHH
VVIAKDTIRVARQAVLIGIFICTALMLIAAFGIIPAFIGAMFQEVIDTVSILWALRARYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NEK
CCC
>Mature Secondary Structure
MRKLSHKQSLMVIIAIALLAVILQFVLGQAWLAQILVSLVGAVMAMTMFIEMIGTLRSGK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
YGVDLLAILAVVSSLLFSEYWAAMVILVMLTGGDALEDYASKKANTELKALLDNSPQVAH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHCCCHHHHH
RLHGEKLEDIAVNQVQVDDKLVIKPGELVPVDGFIVEGSSNFDESSLTGESQPVNKDFND
HHCCCHHHHHHCCEEEECCEEEECCCCEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCH
ELMSGSVNGDAVVTMQASQVAANSKYQQLIKLVKKAEATPARFVRMADRYAVPFTIVAIA
HHHCCCCCCCEEEEEEHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHH
IAVVAAVISKSPSRIAQVLVVASPCPLILAAPVAMVSGMSRASRNGIVVKTGDVLEKLST
HHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHH
AKTVAFDKTGTLTNGHLMVAEILPHQEVSQTELLQIAASVETISSHVLARSLVTYAIDKG
HHHEEECCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LEMLSVSDAQEITANGVQALIQGKLVKVGKRKFVTGDPLIQSQTHTAIYVSRDDQYLGCI
CHHEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEE
TFTDYLRPEASQTMVQLHHLGVKKLMMLSGDQVKTAQKIGQEVGIDDVQAELLPEDKIAA
EEHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHCCCHHHHH
LKALTPEEKPVVMVGDGVNDAPSLVTADVGIAMGAHGSSAASESADLVILKDDLAKVAKA
HHHCCCCCCCEEEECCCCCCCCCCEEEHHHHEECCCCCCCCCCCCCEEEEHHHHHHHHHH
VVIAKDTIRVARQAVLIGIFICTALMLIAAFGIIPAFIGAMFQEVIDTVSILWALRARYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NEK
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]