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The map label for this gene is argK [H]

Identifier: 116332559

GI number: 116332559

Start: 142985

End: 144037

Strand: Reverse

Name: argK [H]

Synonym: LBJ_4125

Alternate gene names: 116332559

Gene position: 144037-142985 (Counterclockwise)

Preceding gene: 116332560

Following gene: 116332558

Centisome position: 48.05

GC content: 43.97

Gene sequence:

>1053_bases
ATGAGTTCTGAAGAACAATCGGGGATTTCTTCTAACGCAAGCGGAGGAATCCGATCCACCGGGATTTCCAGAAAAGTTCT
CCCTACGGTGGAAGAATTCGTAAAAGGAATTCTTTCCGGAAATAGAGCCATGCTCGCCAGAGCGATTACTCTCGTTGAAA
GTTCACGCCCTGAACACAAACAACTTGCAGAAAAAATCATAGGTGCTTCTCTTCCCCATTCCGGTAAATCGATCCGAATC
GGAATCACCGGAATTCCCGGAGTCGGGAAAAGTACGTTCATCGAATCCTTCGGGATGTACACAATCTCTCAAGGAAAAAA
ATTAGCCGTATTGACTATCGATCCTTCCAGTCAAATTTCGGGAGGAAGTATTCTCGGAGATAAGACTAGAATGTCCGAAC
TTTCCAGAAACGAATCCGCCTTTATACGCCCTTCTCCTTCCGGAGAGTCCTTAGGAGGAGTCGCTCGAAAAACGAGGGAA
ACGATCTATCTTTGTGAAGCGGCAGGCTTCGATACGATCTTTGTGGAAACGGTCGGAGTCGGGCAATCGGAAACGGCGGT
ACATTCCATGGTGGATTTGTTTTTACTTCTTCTGATTGCGGGAGCAGGAGACGAACTCCAAGGAATCAAACGTGGAATTA
TGGAAATGGCCGATTTATTCGCTATAACAAAAGCGGATGGAGATAACAAGACAAGAGCCGAAATAACCAGAACCGAAACT
CAATCCGCAATTCATTTTTTTCCGATCAACGAAAGCGGATGGATACCAAAGGCGTTTACCTGCTCCTCTCTTTCGGGAGA
AGGGATTCCCGAAATCTGGAATCAAATTTTAGAATATACTAAAATACTGAAGTCAAATGGTTATTTCGAAATTCGGAGAA
CGAATCAAGCAAAGTATTGGTTGGAAGAGACCGTGTCCGAACATCTTATGGAAGATTTTAAGGCTCAAATGAAAGAATCC
TACAAAGATATGAAAGACAAGGTGAGCCGCCATCAGATCAGCTCTTTTCAAGCGGCTGAGAAATTGATCGCAGAATATCG
AAAACGTATTTAA

Upstream 100 bases:

>100_bases
ATTTTCGGACCGGGAACAAAAATCTCCAAAGCCGCCGTAGGTATTTTGGAACTTCTCATTAAAGATTTAGAAACTTCTAA
AGTAAACGCCTAAGGGAAGA

Downstream 100 bases:

>100_bases
GAATAGATCGATTTAAATTTCAAGGTTTTTATACAAGTGAATGGTCTTCTTTATCATTTTATGGAATGATTTTTTAAGTC
TTTTACTGAAATTTAATTAT

Product: arginine/ornithine transport system ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MSSEEQSGISSNASGGIRSTGISRKVLPTVEEFVKGILSGNRAMLARAITLVESSRPEHKQLAEKIIGASLPHSGKSIRI
GITGIPGVGKSTFIESFGMYTISQGKKLAVLTIDPSSQISGGSILGDKTRMSELSRNESAFIRPSPSGESLGGVARKTRE
TIYLCEAAGFDTIFVETVGVGQSETAVHSMVDLFLLLLIAGAGDELQGIKRGIMEMADLFAITKADGDNKTRAEITRTET
QSAIHFFPINESGWIPKAFTCSSLSGEGIPEIWNQILEYTKILKSNGYFEIRRTNQAKYWLEETVSEHLMEDFKAQMKES
YKDMKDKVSRHQISSFQAAEKLIAEYRKRI

Sequences:

>Translated_350_residues
MSSEEQSGISSNASGGIRSTGISRKVLPTVEEFVKGILSGNRAMLARAITLVESSRPEHKQLAEKIIGASLPHSGKSIRI
GITGIPGVGKSTFIESFGMYTISQGKKLAVLTIDPSSQISGGSILGDKTRMSELSRNESAFIRPSPSGESLGGVARKTRE
TIYLCEAAGFDTIFVETVGVGQSETAVHSMVDLFLLLLIAGAGDELQGIKRGIMEMADLFAITKADGDNKTRAEITRTET
QSAIHFFPINESGWIPKAFTCSSLSGEGIPEIWNQILEYTKILKSNGYFEIRRTNQAKYWLEETVSEHLMEDFKAQMKES
YKDMKDKVSRHQISSFQAAEKLIAEYRKRI
>Mature_349_residues
SSEEQSGISSNASGGIRSTGISRKVLPTVEEFVKGILSGNRAMLARAITLVESSRPEHKQLAEKIIGASLPHSGKSIRIG
ITGIPGVGKSTFIESFGMYTISQGKKLAVLTIDPSSQISGGSILGDKTRMSELSRNESAFIRPSPSGESLGGVARKTRET
IYLCEAAGFDTIFVETVGVGQSETAVHSMVDLFLLLLIAGAGDELQGIKRGIMEMADLFAITKADGDNKTRAEITRTETQ
SAIHFFPINESGWIPKAFTCSSLSGEGIPEIWNQILEYTKILKSNGYFEIRRTNQAKYWLEETVSEHLMEDFKAQMKESY
KDMKDKVSRHQISSFQAAEKLIAEYRKRI

Specific function: Phosphorylates the AO and LAO periplasmic-binding proteins [H]

COG id: COG1703

COG function: function code E; Putative periplasmic protein kinase ArgK and related GTPases of G3E family

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgK family [H]

Homologues:

Organism=Homo sapiens, GI26892295, Length=341, Percent_Identity=44.8680351906158, Blast_Score=281, Evalue=5e-76,
Organism=Escherichia coli, GI1789285, Length=324, Percent_Identity=46.6049382716049, Blast_Score=307, Evalue=6e-85,
Organism=Caenorhabditis elegans, GI71994271, Length=332, Percent_Identity=42.7710843373494, Blast_Score=265, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI71994275, Length=271, Percent_Identity=45.7564575645756, Blast_Score=241, Evalue=3e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005129
- InterPro:   IPR016121 [H]

Pfam domain/function: PF03308 ArgK [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 38342; Mature: 38211

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSEEQSGISSNASGGIRSTGISRKVLPTVEEFVKGILSGNRAMLARAITLVESSRPEHK
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHH
QLAEKIIGASLPHSGKSIRIGITGIPGVGKSTFIESFGMYTISQGKKLAVLTIDPSSQIS
HHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCEEECCCCEEEEEEECCCCCCC
GGSILGDKTRMSELSRNESAFIRPSPSGESLGGVARKTRETIYLCEAAGFDTIFVETVGV
CCCEECCHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHEEEEEECCCCCEEEEEEECC
GQSETAVHSMVDLFLLLLIAGAGDELQGIKRGIMEMADLFAITKADGDNKTRAEITRTET
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHC
QSAIHFFPINESGWIPKAFTCSSLSGEGIPEIWNQILEYTKILKSNGYFEIRRTNQAKYW
CCEEEEEECCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHH
LEETVSEHLMEDFKAQMKESYKDMKDKVSRHQISSFQAAEKLIAEYRKRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSEEQSGISSNASGGIRSTGISRKVLPTVEEFVKGILSGNRAMLARAITLVESSRPEHK
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHH
QLAEKIIGASLPHSGKSIRIGITGIPGVGKSTFIESFGMYTISQGKKLAVLTIDPSSQIS
HHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCEEECCCCEEEEEEECCCCCCC
GGSILGDKTRMSELSRNESAFIRPSPSGESLGGVARKTRETIYLCEAAGFDTIFVETVGV
CCCEECCHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHEEEEEECCCCCEEEEEEECC
GQSETAVHSMVDLFLLLLIAGAGDELQGIKRGIMEMADLFAITKADGDNKTRAEITRTET
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHC
QSAIHFFPINESGWIPKAFTCSSLSGEGIPEIWNQILEYTKILKSNGYFEIRRTNQAKYW
CCEEEEEECCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHH
LEETVSEHLMEDFKAQMKESYKDMKDKVSRHQISSFQAAEKLIAEYRKRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Arg [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9733684; 9278503 [H]