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The map label for this gene is crp [C]

Identifier: 116332472

GI number: 116332472

Start: 31048

End: 31416

Strand: Direct

Name: crp [C]

Synonym: LBJ_4028

Alternate gene names: 116332472

Gene position: 31048-31416 (Clockwise)

Preceding gene: 116332469

Following gene: 116332473

Centisome position: 10.36

GC content: 43.09

Gene sequence:

>369_bases
ATGAATAAAATGGAGATCCCTGCCGGAGGAATCGTTTTTAAAGAAGGCGAGATGAATAACGCGATGTATGTGATTCTTTC
CGGTTCTGTAGAAGTTTTTTTTACGCGAAAAAATATCGTCCAGCGTCTTGCCGTGATGAATAAAGGAGATTTTTTTGGAG
AAATGGCGTTGTTTCGTGCAAGGCCGAGGACTGCGACCGCAAAAGCGATTTTGGATTGCCAGCTTGCAGTCATCGAGAGT
AAACAACAGCTTGAGAAGTTCCTAATCAAAAATCCGGATTTTTCCGTCAAAATGGTTCGAATACTTGCCGATCGTTTGGC
AAACACCGATGAGCTTCTTGGCTCGACACTGGAAGAATTTTGCGAGTAA

Upstream 100 bases:

>100_bases
TCATAAAAAGAATATGCTTTTTCGGTAGTGGAATTAGTATTCATTTGTCTATAGATGATTTTTTGATAAAGAAAGAAATC
TTTTTAGGTCGGTTTAATAA

Downstream 100 bases:

>100_bases
GTGCGTAAGATTTTAAAAATGCCATCTTCGTTTATTGTTTTTTCTATTTCTGTAAAATAGAGTTGTTGAAAAATTCCATG
ATTCGGATTAACAAAATGCG

Product: cyclic nucleotide-binding protein

Products: NA

Alternate protein names: Transcriptional Regulator Crp/Fnr Family; CRP/FNR Family Transcriptional Regulator; Crp Family Transcriptional Regulator; Potassium Channel Protein; Transcriptional Regulator; Crp/FNR Family Transcriptional Regulator; Transcriptional Regulatory Protein; Crp Family Regulatory Protein; Mechanosensitive Ion Channel Protein MscS; CAMP-Dependent Protein Kinase

Number of amino acids: Translated: 122; Mature: 122

Protein sequence:

>122_residues
MNKMEIPAGGIVFKEGEMNNAMYVILSGSVEVFFTRKNIVQRLAVMNKGDFFGEMALFRARPRTATAKAILDCQLAVIES
KQQLEKFLIKNPDFSVKMVRILADRLANTDELLGSTLEEFCE

Sequences:

>Translated_122_residues
MNKMEIPAGGIVFKEGEMNNAMYVILSGSVEVFFTRKNIVQRLAVMNKGDFFGEMALFRARPRTATAKAILDCQLAVIES
KQQLEKFLIKNPDFSVKMVRILADRLANTDELLGSTLEEFCE
>Mature_122_residues
MNKMEIPAGGIVFKEGEMNNAMYVILSGSVEVFFTRKNIVQRLAVMNKGDFFGEMALFRARPRTATAKAILDCQLAVIES
KQQLEKFLIKNPDFSVKMVRILADRLANTDELLGSTLEEFCE

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 13753; Mature: 13753

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS00889 CNMP_BINDING_2 ; PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKMEIPAGGIVFKEGEMNNAMYVILSGSVEVFFTRKNIVQRLAVMNKGDFFGEMALFRA
CCCCCCCCCCEEEECCCCCCEEEEEEECCEEEEEEHHHHHHHHHHHCCCCHHHHHHHHHC
RPRTATAKAILDCQLAVIESKQQLEKFLIKNPDFSVKMVRILADRLANTDELLGSTLEEF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
CE
CC
>Mature Secondary Structure
MNKMEIPAGGIVFKEGEMNNAMYVILSGSVEVFFTRKNIVQRLAVMNKGDFFGEMALFRA
CCCCCCCCCCEEEECCCCCCEEEEEEECCEEEEEEHHHHHHHHHHHCCCCHHHHHHHHHC
RPRTATAKAILDCQLAVIESKQQLEKFLIKNPDFSVKMVRILADRLANTDELLGSTLEEF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
CE
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA