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The map label for this gene is ephD [H]

Identifier: 116329276

GI number: 116329276

Start: 3220883

End: 3221770

Strand: Reverse

Name: ephD [H]

Synonym: LBL_2719

Alternate gene names: 116329276

Gene position: 3221770-3220883 (Counterclockwise)

Preceding gene: 116329278

Following gene: 116329270

Centisome position: 89.14

GC content: 39.64

Gene sequence:

>888_bases
TTGAAGTACACATACATAGAAAATCAAAAAGTAAAATTATTTCTCTCTTATTCAGACACGGATTCGAAGAATGTTATCCT
ATTCATCCACGGATACCCGGATACTCATAAAACCTGGGACTTCCAGATCGAATCCTTAAAGGAAAGATTCAGGTTAGGTG
CGATCGACTTAAGAGGTTTCGGCAGGTCTTCCAAACCTTTGGAACAATCCGAATACAACTATGCGGTGATACTTCCCGAT
CTATTAAAAGCGATCAATTTTCTGTCCAAGAATAACAAGGTACATATAGTCGGTCACGATTGGGGGGCTACACTCGGCTG
GTTGTTTATTAGTGATCCGGAATATTCTAAATACGTAAATTCTTTTACTGCGATTTCCGGTCCTCATCCCTGGCTTGCGG
GTAAACGAATGATCGACGATCTATTTAGTCTCAATTTTGATAATTGGAAAAAAGTAATTGATCAGAGTTTTCGCTCCTGG
TACATCTGGTTTTTTCAAATTCCGATTCTCCCAGAATTGATGTGGCAAAATTTCGGTGAATTGATTTACAAATGGATCAT
GGACTTCGGCGGAGTTCCCCAAAAGGATTTCCTCCGGAAAGTGAATCGAAACGATATCTACAGTGCAACGATCGCCCCCA
TCAATCTGTTTCGGGAATTATTGTTCGGTGGAACAGTAATCTCCGCTCCTTCCAACATCAAAGTCCCTGTGCAATTAATT
ATTCCTCAAAAGGATTTTATCGTTCTTCCGGAAGTATATGAAAATGCATATGAGTATGTTGATAGCTTAGAAATTCATAA
ACTGGATTCTAACCATTGGGTGCACCGAGAACAACCGAACGTAGTGACGGAGTTGATTCAAAAGTTCGTTTCCAAACATT
CTATATAA

Upstream 100 bases:

>100_bases
CAACGAAGTCGAGATTCCGTAAAAAGACTGGAAAATTTGTCGCTAAAAACAACGATAGCAGGACGGTTTTCCTTCCGGGG
CAAAGAAGGAGGTTAAAATT

Downstream 100 bases:

>100_bases
CAGTATCTAGGCATATTAGGTTTAACTTGTATATGCAAAGATCCATAAAAAATCAAACGCTCTAAACGGAATACGATGAA
AGTCTGTTTGAACGAGGATT

Product: hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MKYTYIENQKVKLFLSYSDTDSKNVILFIHGYPDTHKTWDFQIESLKERFRLGAIDLRGFGRSSKPLEQSEYNYAVILPD
LLKAINFLSKNNKVHIVGHDWGATLGWLFISDPEYSKYVNSFTAISGPHPWLAGKRMIDDLFSLNFDNWKKVIDQSFRSW
YIWFFQIPILPELMWQNFGELIYKWIMDFGGVPQKDFLRKVNRNDIYSATIAPINLFRELLFGGTVISAPSNIKVPVQLI
IPQKDFIVLPEVYENAYEYVDSLEIHKLDSNHWVHREQPNVVTELIQKFVSKHSI

Sequences:

>Translated_295_residues
MKYTYIENQKVKLFLSYSDTDSKNVILFIHGYPDTHKTWDFQIESLKERFRLGAIDLRGFGRSSKPLEQSEYNYAVILPD
LLKAINFLSKNNKVHIVGHDWGATLGWLFISDPEYSKYVNSFTAISGPHPWLAGKRMIDDLFSLNFDNWKKVIDQSFRSW
YIWFFQIPILPELMWQNFGELIYKWIMDFGGVPQKDFLRKVNRNDIYSATIAPINLFRELLFGGTVISAPSNIKVPVQLI
IPQKDFIVLPEVYENAYEYVDSLEIHKLDSNHWVHREQPNVVTELIQKFVSKHSI
>Mature_295_residues
MKYTYIENQKVKLFLSYSDTDSKNVILFIHGYPDTHKTWDFQIESLKERFRLGAIDLRGFGRSSKPLEQSEYNYAVILPD
LLKAINFLSKNNKVHIVGHDWGATLGWLFISDPEYSKYVNSFTAISGPHPWLAGKRMIDDLFSLNFDNWKKVIDQSFRSW
YIWFFQIPILPELMWQNFGELIYKWIMDFGGVPQKDFLRKVNRNDIYSATIAPINLFRELLFGGTVISAPSNIKVPVQLI
IPQKDFIVLPEVYENAYEYVDSLEIHKLDSNHWVHREQPNVVTELIQKFVSKHSI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI218777837, Length=305, Percent_Identity=24.5901639344262, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI218777840, Length=302, Percent_Identity=27.4834437086093, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI13376164, Length=302, Percent_Identity=27.4834437086093, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17554012, Length=300, Percent_Identity=26.6666666666667, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17562298, Length=302, Percent_Identity=23.1788079470199, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00106 adh_short [H]

EC number: NA

Molecular weight: Translated: 34619; Mature: 34619

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYTYIENQKVKLFLSYSDTDSKNVILFIHGYPDTHKTWDFQIESLKERFRLGAIDLRGF
CCEEEECCCEEEEEEEECCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEECC
GRSSKPLEQSEYNYAVILPDLLKAINFLSKNNKVHIVGHDWGATLGWLFISDPEYSKYVN
CCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCCCHHHHHH
SFTAISGPHPWLAGKRMIDDLFSLNFDNWKKVIDQSFRSWYIWFFQIPILPELMWQNFGE
HHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHH
LIYKWIMDFGGVPQKDFLRKVNRNDIYSATIAPINLFRELLFGGTVISAPSNIKVPVQLI
HHHHHHHHHCCCCHHHHHHHCCCCCCEEEHHHHHHHHHHHHHCCEEEECCCCCCEEEEEE
IPQKDFIVLPEVYENAYEYVDSLEIHKLDSNHWVHREQPNVVTELIQKFVSKHSI
ECCCCEEECCHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKYTYIENQKVKLFLSYSDTDSKNVILFIHGYPDTHKTWDFQIESLKERFRLGAIDLRGF
CCEEEECCCEEEEEEEECCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEECC
GRSSKPLEQSEYNYAVILPDLLKAINFLSKNNKVHIVGHDWGATLGWLFISDPEYSKYVN
CCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCCCHHHHHH
SFTAISGPHPWLAGKRMIDDLFSLNFDNWKKVIDQSFRSWYIWFFQIPILPELMWQNFGE
HHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHH
LIYKWIMDFGGVPQKDFLRKVNRNDIYSATIAPINLFRELLFGGTVISAPSNIKVPVQLI
HHHHHHHHHCCCCHHHHHHHCCCCCCEEEHHHHHHHHHHHHHCCEEEECCCCCCEEEEEE
IPQKDFIVLPEVYENAYEYVDSLEIHKLDSNHWVHREQPNVVTELIQKFVSKHSI
ECCCCEEECCHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]