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The map label for this gene is manB-1 [H]

Identifier: 116329269

GI number: 116329269

Start: 3212428

End: 3213810

Strand: Reverse

Name: manB-1 [H]

Synonym: LBL_2710

Alternate gene names: 116329269

Gene position: 3213810-3212428 (Counterclockwise)

Preceding gene: 116329270

Following gene: 116329268

Centisome position: 88.92

GC content: 46.06

Gene sequence:

>1383_bases
ATGAATACAAAAGTCCCCGTATTCAATCATCCGGATCTCATGGTTTCCGTTTCTGGGATTCGAGGAATCATTCCTACAGG
ACTTTCTCCTGAAGTTATTTTTAATGCGCTGCGTGCTTTCGGTACATGGATCGAAGGATCTAAAGTTGTGATCGGTCGCG
ATTCCAGACCTTCCGGACCTTATATCGAAAACATTGCCTTAGGTTTGATGCAGGCGATGGGAAAAGACGTCCTACAACTC
GGAATTGTTCCGACTCCCACCGTAAAAGCGGTCGTTAATCTTTCCAAAGCGGGAGGTGGAATCATGATCAGTGCCTCTCA
CAACCCGATTCTATGGAATGCGTTTAAATTTATAGGTCCAGGCGGATTTTTTACCGGAGCGGCGGATTTGGAACAAATTC
TGGACACGGTTCGAAATCAATCCTATAGACAAATTCAATACAAACCTTCTTCTAAAATCGTTTCCGGAAAAGAATGGTCT
GAAAAACACATCGAGTCCGTTCTCAAACGAGTGAACGTGAGCGCAATTCGAAAGAAAAAATACAAGGTTCTCGTAGACGC
AGTCAATGGAGCGGGAAGCGCCTTAATTCCGGAACTTCTGGGAAAACTCGGATGTAAGCCGATCCTTTTACATTGTAGTC
CGGACGGAACCTTTCCAAGGCCACCGGAACCGACTCCGGACGCTCTCAAACAAACTTCTCGAAAGATGAAATCTTCCGGT
GCCGATATCGGCTTTGCTCTGGATCCGGACGCGGATCGGCTTGTCGTTCTCACTCCGAAAAAAGGAGCAATCTCCGAAGA
ATATACTCTCCCTTTGAGTTTTCTTTCTCTCACTCTGGGGAAGATGCCTAAAAAGGCCAATCTGGTCGTAAATCTTTCCA
CAAGTTTTATCAACGAGTTCGTGGCGGGACAATACGGTGTTCCCGTTTCTCGTTCCAAAGTAGGAGAAGCGAACGTAGTG
TCTGAAATGCTTCGCCAAAAATCGATTTTCGGTGGAGAAGGAAACGGAGGAGTAATAGATCCCGCAATCGCTTCCTTTGG
AAGAGATTCACTCTCCGGAATTGCACATATCCTAAATGGAATGGCTGCGACGGGAAAGAAGATCGATTCGATCGTAGAAG
AACTTCCCGCGGTTCATATGCAGAAAACCAGCTTCAAAGTGGCTGGTAAAAATCTCCAAGATATCTATTCCAAGTTCAGT
GAAGAATTTTCGGCTTTCTCCGAAGAAACTCTGGACGGCTTGCGCTTAGCTTCCGAGGATTCTTGGATTCACATTCGTCC
TTCTAACACGGAGCCGATCATACGAGTTATAGCGGAAGCGAGAACCAAAAAAGATCTCAATTCTCTGCTCGACCGTTCGA
GAAGTCTCATGGAGAATGCCTGA

Upstream 100 bases:

>100_bases
TCAGCTGGTAGAGCGCCTGCCTTACAAGCAGGATGTCGGCAGTTCGATCCTGTCATCGCCCATATACTTTTTCCGGAGAA
ATTAACTATTTCTAAAACTT

Downstream 100 bases:

>100_bases
ATATGTGTGGAATCGTCGGTTATGCGGGTAAAAAGAATGCGGAATCAGTACTGGTAGTAGGTCTAATCTGTCTCGAATAT
AGAGGTTATGATTCGGCCGG

Product: phosphomannomutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MNTKVPVFNHPDLMVSVSGIRGIIPTGLSPEVIFNALRAFGTWIEGSKVVIGRDSRPSGPYIENIALGLMQAMGKDVLQL
GIVPTPTVKAVVNLSKAGGGIMISASHNPILWNAFKFIGPGGFFTGAADLEQILDTVRNQSYRQIQYKPSSKIVSGKEWS
EKHIESVLKRVNVSAIRKKKYKVLVDAVNGAGSALIPELLGKLGCKPILLHCSPDGTFPRPPEPTPDALKQTSRKMKSSG
ADIGFALDPDADRLVVLTPKKGAISEEYTLPLSFLSLTLGKMPKKANLVVNLSTSFINEFVAGQYGVPVSRSKVGEANVV
SEMLRQKSIFGGEGNGGVIDPAIASFGRDSLSGIAHILNGMAATGKKIDSIVEELPAVHMQKTSFKVAGKNLQDIYSKFS
EEFSAFSEETLDGLRLASEDSWIHIRPSNTEPIIRVIAEARTKKDLNSLLDRSRSLMENA

Sequences:

>Translated_460_residues
MNTKVPVFNHPDLMVSVSGIRGIIPTGLSPEVIFNALRAFGTWIEGSKVVIGRDSRPSGPYIENIALGLMQAMGKDVLQL
GIVPTPTVKAVVNLSKAGGGIMISASHNPILWNAFKFIGPGGFFTGAADLEQILDTVRNQSYRQIQYKPSSKIVSGKEWS
EKHIESVLKRVNVSAIRKKKYKVLVDAVNGAGSALIPELLGKLGCKPILLHCSPDGTFPRPPEPTPDALKQTSRKMKSSG
ADIGFALDPDADRLVVLTPKKGAISEEYTLPLSFLSLTLGKMPKKANLVVNLSTSFINEFVAGQYGVPVSRSKVGEANVV
SEMLRQKSIFGGEGNGGVIDPAIASFGRDSLSGIAHILNGMAATGKKIDSIVEELPAVHMQKTSFKVAGKNLQDIYSKFS
EEFSAFSEETLDGLRLASEDSWIHIRPSNTEPIIRVIAEARTKKDLNSLLDRSRSLMENA
>Mature_460_residues
MNTKVPVFNHPDLMVSVSGIRGIIPTGLSPEVIFNALRAFGTWIEGSKVVIGRDSRPSGPYIENIALGLMQAMGKDVLQL
GIVPTPTVKAVVNLSKAGGGIMISASHNPILWNAFKFIGPGGFFTGAADLEQILDTVRNQSYRQIQYKPSSKIVSGKEWS
EKHIESVLKRVNVSAIRKKKYKVLVDAVNGAGSALIPELLGKLGCKPILLHCSPDGTFPRPPEPTPDALKQTSRKMKSSG
ADIGFALDPDADRLVVLTPKKGAISEEYTLPLSFLSLTLGKMPKKANLVVNLSTSFINEFVAGQYGVPVSRSKVGEANVV
SEMLRQKSIFGGEGNGGVIDPAIASFGRDSLSGIAHILNGMAATGKKIDSIVEELPAVHMQKTSFKVAGKNLQDIYSKFS
EEFSAFSEETLDGLRLASEDSWIHIRPSNTEPIIRVIAEARTKKDLNSLLDRSRSLMENA

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1788361, Length=464, Percent_Identity=25, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1789566, Length=444, Percent_Identity=25.4504504504505, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.10 [H]

Molecular weight: Translated: 49606; Mature: 49606

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTKVPVFNHPDLMVSVSGIRGIIPTGLSPEVIFNALRAFGTWIEGSKVVIGRDSRPSGP
CCCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCC
YIENIALGLMQAMGKDVLQLGIVPTPTVKAVVNLSKAGGGIMISASHNPILWNAFKFIGP
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCEEEEHHHHHCC
GGFFTGAADLEQILDTVRNQSYRQIQYKPSSKIVSGKEWSEKHIESVLKRVNVSAIRKKK
CCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHH
YKVLVDAVNGAGSALIPELLGKLGCKPILLHCSPDGTFPRPPEPTPDALKQTSRKMKSSG
HEEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCC
ADIGFALDPDADRLVVLTPKKGAISEEYTLPLSFLSLTLGKMPKKANLVVNLSTSFINEF
CCEEEEECCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEHHHHHHHH
VAGQYGVPVSRSKVGEANVVSEMLRQKSIFGGEGNGGVIDPAIASFGRDSLSGIAHILNG
HCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEECHHHHHCCCHHHHHHHHHHHH
MAATGKKIDSIVEELPAVHMQKTSFKVAGKNLQDIYSKFSEEFSAFSEETLDGLRLASED
HHHCHHHHHHHHHHCCHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCC
SWIHIRPSNTEPIIRVIAEARTKKDLNSLLDRSRSLMENA
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNTKVPVFNHPDLMVSVSGIRGIIPTGLSPEVIFNALRAFGTWIEGSKVVIGRDSRPSGP
CCCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCC
YIENIALGLMQAMGKDVLQLGIVPTPTVKAVVNLSKAGGGIMISASHNPILWNAFKFIGP
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCEEEEHHHHHCC
GGFFTGAADLEQILDTVRNQSYRQIQYKPSSKIVSGKEWSEKHIESVLKRVNVSAIRKKK
CCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHH
YKVLVDAVNGAGSALIPELLGKLGCKPILLHCSPDGTFPRPPEPTPDALKQTSRKMKSSG
HEEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCC
ADIGFALDPDADRLVVLTPKKGAISEEYTLPLSFLSLTLGKMPKKANLVVNLSTSFINEF
CCEEEEECCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEHHHHHHHH
VAGQYGVPVSRSKVGEANVVSEMLRQKSIFGGEGNGGVIDPAIASFGRDSLSGIAHILNG
HCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEECHHHHHCCCHHHHHHHHHHHH
MAATGKKIDSIVEELPAVHMQKTSFKVAGKNLQDIYSKFSEEFSAFSEETLDGLRLASED
HHHCHHHHHHHHHHCCHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCC
SWIHIRPSNTEPIIRVIAEARTKKDLNSLLDRSRSLMENA
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA