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The map label for this gene is glmS [H]

Identifier: 116329268

GI number: 116329268

Start: 3210593

End: 3212425

Strand: Reverse

Name: glmS [H]

Synonym: LBL_2709

Alternate gene names: 116329268

Gene position: 3212425-3210593 (Counterclockwise)

Preceding gene: 116329269

Following gene: 116329267

Centisome position: 88.88

GC content: 44.08

Gene sequence:

>1833_bases
ATGTGTGGAATCGTCGGTTATGCGGGTAAAAAGAATGCGGAATCAGTACTGGTAGTAGGTCTAATCTGTCTCGAATATAG
AGGTTATGATTCGGCCGGGATTGCGGTTTTGGATCAGGGCGATATTTTGGTTCGTAAGGCGAAAGGAAAGATCAAAGACC
TGGAAGCTTACTTGCGCGAATTCCCTGCACCGGGTAACGTAGGGATCGGACACACTCGTTGGGCGACTCACGGAGAGCCG
AATCAGATCAACGCCCATCCACACACGGATTCCAACTCGACAGTTGCTGTTGTACATAACGGAATCATCGAAAACTATCT
CGAACTCAAAAGCGAGTTAAAGAAAAAGGGACACGTATTTCAAAGTTTAACCGATACGGAAGTTCTTCCTCATTTGCTCG
AAGAAAGCAAAAAGAACGGCAAATCCAACAAGGACGCATTTTTAGAACTTTTTGGAAAGATCCACGGAAAGTGGGCTATT
TCCACCGTATTTGAAACCGAACCCGATCGTGTTTACTTCGCCCAAGACGGGGCGCCCCTTTTGATCGGAAAAGGAAAAGG
GGAATACTTTTTAGCCTCCGATATTTCTCCTCTTACCAGAAACTGCGAAGAAGTATATTATGTAAGCTCCGGAGAATGGG
GTTATTTCTCTCAAAACGAATTCAAACTTTTGGATTTTTCCGGAAAGGAGCTTACGCCCGTATTCAAAAAACAGGAACTC
CGCTGGGAAGATCTAGACAAGGGTGGTTATCCTCACTACATGATCAAGGAGATTCACGAACAAGCAGGAATCTTCCGTAA
AATTATCCAAGAAAGAATATTAGATAACGGTGAAATTGTTTTTCCGGAAATCAAACTAAGTAAAGACGTACTCTCCAGGG
TCAATAGAATCATCATCCAAGCGGCAGGAACTAGTTATTACGCCGGAATGATCGGCAAACATTATCTCGAGAATTTCGCA
AAGCTTCAAACCGATACGGAAGCGTCTTCGGAGTTTCGTTATAGGAATCCGGTCGTAGAAGGAGATACCCTTATTATGGG
GATCTCTCAGTCCGGTGAAACCGCGGACACGTTAGCTTCCATTCATGAAGCAAAAGCTAAGTTCATCAAAGTGGTCTCTC
TCGTGAACAACGTAAATTCCACGATTGCAAGAGAATCGGATTCTTATATCCGAACCGACGCTGGTCCCGAAATCGGAGTC
GCGAGTACAAAAGCGTTTACGGCCCAGGTTTTAAATCTTCTTTTATTTTCGATTTATATGGCCAATCTCAAGTGGCTCAT
CAGCGACGAAGAGAGAAAAACGCTCATCGAAGAAATCAGGTTACTTCCTGCTAAGATAGATCGGATTCTCACACAGGCGA
GTAAGATCGAACGGATGTCTTCTCATTTTACGACCGCAAAGGATTTTATTTTTTTAGGGAGAACTTATAATCATCCTGTT
GCACTGGAAGGCGCTTTGAAGTTAAAGGAAATTTCTTATATTCACGCCTCCGGTTACGCAGGCGGAGAATTCAAACACGG
GCCGATCGCGCTCATCACTAGTGAAGTTCCCGTAGTTTGTATCGCTCCCAAGTCGGAAATTTATACGAAAATGGTTTCTA
ACATTCAGGAAATCAAAGCGAGAAAAGGAATCATCATCTCGATTGTGACCGAAGGAGATCAAGAAGCGAAATCTCTTTCG
GACTATTCTTTTGAAATTCCGGAATGTTCCGAGATTTTAAGCCCGATCTTGAACGTGATTCCTTTGCAATTACTCGCATA
TTATTCAGCGATCGCCCGAGGCTGTCCTCCGGATCAGCCCAGAAACCTGGCTAAGTCCGTAACCGTAGAGTAA

Upstream 100 bases:

>100_bases
ACACGGAGCCGATCATACGAGTTATAGCGGAAGCGAGAACCAAAAAAGATCTCAATTCTCTGCTCGACCGTTCGAGAAGT
CTCATGGAGAATGCCTGAAT

Downstream 100 bases:

>100_bases
GTAGTTTATGCCGAAGGTTCAGAGAATTCTCATCGATGAAAGAGAGATTCCTATCGGCTTACGTTCTCTAACGCGTATTC
GATCTTTTTCGGAGATTCGC

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 610; Mature: 610

Protein sequence:

>610_residues
MCGIVGYAGKKNAESVLVVGLICLEYRGYDSAGIAVLDQGDILVRKAKGKIKDLEAYLREFPAPGNVGIGHTRWATHGEP
NQINAHPHTDSNSTVAVVHNGIIENYLELKSELKKKGHVFQSLTDTEVLPHLLEESKKNGKSNKDAFLELFGKIHGKWAI
STVFETEPDRVYFAQDGAPLLIGKGKGEYFLASDISPLTRNCEEVYYVSSGEWGYFSQNEFKLLDFSGKELTPVFKKQEL
RWEDLDKGGYPHYMIKEIHEQAGIFRKIIQERILDNGEIVFPEIKLSKDVLSRVNRIIIQAAGTSYYAGMIGKHYLENFA
KLQTDTEASSEFRYRNPVVEGDTLIMGISQSGETADTLASIHEAKAKFIKVVSLVNNVNSTIARESDSYIRTDAGPEIGV
ASTKAFTAQVLNLLLFSIYMANLKWLISDEERKTLIEEIRLLPAKIDRILTQASKIERMSSHFTTAKDFIFLGRTYNHPV
ALEGALKLKEISYIHASGYAGGEFKHGPIALITSEVPVVCIAPKSEIYTKMVSNIQEIKARKGIIISIVTEGDQEAKSLS
DYSFEIPECSEILSPILNVIPLQLLAYYSAIARGCPPDQPRNLAKSVTVE

Sequences:

>Translated_610_residues
MCGIVGYAGKKNAESVLVVGLICLEYRGYDSAGIAVLDQGDILVRKAKGKIKDLEAYLREFPAPGNVGIGHTRWATHGEP
NQINAHPHTDSNSTVAVVHNGIIENYLELKSELKKKGHVFQSLTDTEVLPHLLEESKKNGKSNKDAFLELFGKIHGKWAI
STVFETEPDRVYFAQDGAPLLIGKGKGEYFLASDISPLTRNCEEVYYVSSGEWGYFSQNEFKLLDFSGKELTPVFKKQEL
RWEDLDKGGYPHYMIKEIHEQAGIFRKIIQERILDNGEIVFPEIKLSKDVLSRVNRIIIQAAGTSYYAGMIGKHYLENFA
KLQTDTEASSEFRYRNPVVEGDTLIMGISQSGETADTLASIHEAKAKFIKVVSLVNNVNSTIARESDSYIRTDAGPEIGV
ASTKAFTAQVLNLLLFSIYMANLKWLISDEERKTLIEEIRLLPAKIDRILTQASKIERMSSHFTTAKDFIFLGRTYNHPV
ALEGALKLKEISYIHASGYAGGEFKHGPIALITSEVPVVCIAPKSEIYTKMVSNIQEIKARKGIIISIVTEGDQEAKSLS
DYSFEIPECSEILSPILNVIPLQLLAYYSAIARGCPPDQPRNLAKSVTVE
>Mature_610_residues
MCGIVGYAGKKNAESVLVVGLICLEYRGYDSAGIAVLDQGDILVRKAKGKIKDLEAYLREFPAPGNVGIGHTRWATHGEP
NQINAHPHTDSNSTVAVVHNGIIENYLELKSELKKKGHVFQSLTDTEVLPHLLEESKKNGKSNKDAFLELFGKIHGKWAI
STVFETEPDRVYFAQDGAPLLIGKGKGEYFLASDISPLTRNCEEVYYVSSGEWGYFSQNEFKLLDFSGKELTPVFKKQEL
RWEDLDKGGYPHYMIKEIHEQAGIFRKIIQERILDNGEIVFPEIKLSKDVLSRVNRIIIQAAGTSYYAGMIGKHYLENFA
KLQTDTEASSEFRYRNPVVEGDTLIMGISQSGETADTLASIHEAKAKFIKVVSLVNNVNSTIARESDSYIRTDAGPEIGV
ASTKAFTAQVLNLLLFSIYMANLKWLISDEERKTLIEEIRLLPAKIDRILTQASKIERMSSHFTTAKDFIFLGRTYNHPV
ALEGALKLKEISYIHASGYAGGEFKHGPIALITSEVPVVCIAPKSEIYTKMVSNIQEIKARKGIIISIVTEGDQEAKSLS
DYSFEIPECSEILSPILNVIPLQLLAYYSAIARGCPPDQPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI205277386, Length=689, Percent_Identity=33.6719883889695, Blast_Score=353, Evalue=3e-97,
Organism=Homo sapiens, GI4826742, Length=685, Percent_Identity=32.2627737226277, Blast_Score=349, Evalue=5e-96,
Organism=Escherichia coli, GI1790167, Length=616, Percent_Identity=42.0454545454545, Blast_Score=481, Evalue=1e-137,
Organism=Escherichia coli, GI1788651, Length=143, Percent_Identity=32.8671328671329, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI87082251, Length=311, Percent_Identity=20.9003215434084, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17539970, Length=720, Percent_Identity=33.1944444444444, Blast_Score=320, Evalue=1e-87,
Organism=Caenorhabditis elegans, GI17532899, Length=432, Percent_Identity=34.7222222222222, Blast_Score=252, Evalue=4e-67,
Organism=Caenorhabditis elegans, GI17532897, Length=432, Percent_Identity=34.7222222222222, Blast_Score=252, Evalue=4e-67,
Organism=Saccharomyces cerevisiae, GI6322745, Length=451, Percent_Identity=33.0376940133038, Blast_Score=268, Evalue=2e-72,
Organism=Saccharomyces cerevisiae, GI6323731, Length=433, Percent_Identity=29.5612009237875, Blast_Score=196, Evalue=9e-51,
Organism=Saccharomyces cerevisiae, GI6323730, Length=212, Percent_Identity=38.2075471698113, Blast_Score=113, Evalue=8e-26,
Organism=Drosophila melanogaster, GI21357745, Length=684, Percent_Identity=34.0643274853801, Blast_Score=379, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 67832; Mature: 67832

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGYAGKKNAESVLVVGLICLEYRGYDSAGIAVLDQGDILVRKAKGKIKDLEAYLRE
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEECCCCHHHHHHHHHH
FPAPGNVGIGHTRWATHGEPNQINAHPHTDSNSTVAVVHNGIIENYLELKSELKKKGHVF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCHHH
QSLTDTEVLPHLLEESKKNGKSNKDAFLELFGKIHGKWAISTVFETEPDRVYFAQDGAPL
HHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCEEEEECCCCEE
LIGKGKGEYFLASDISPLTRNCEEVYYVSSGEWGYFSQNEFKLLDFSGKELTPVFKKQEL
EEECCCCCEEEECCCCHHHCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCCHHHHHHCC
RWEDLDKGGYPHYMIKEIHEQAGIFRKIIQERILDNGEIVFPEIKLSKDVLSRVNRIIIQ
CHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHCCHHHHHHHHHEEEE
AAGTSYYAGMIGKHYLENFAKLQTDTEASSEFRYRNPVVEGDTLIMGISQSGETADTLAS
ECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCCEEEEEECCCCCHHHHHHH
IHEAKAKFIKVVSLVNNVNSTIARESDSYIRTDAGPEIGVASTKAFTAQVLNLLLFSIYM
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ANLKWLISDEERKTLIEEIRLLPAKIDRILTQASKIERMSSHFTTAKDFIFLGRTYNHPV
HHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEECCCCCCCE
ALEGALKLKEISYIHASGYAGGEFKHGPIALITSEVPVVCIAPKSEIYTKMVSNIQEIKA
EECCCEEEEHEEEEEECCCCCCCCCCCCEEEEECCCCEEEECCHHHHHHHHHHHHHHHHH
RKGIIISIVTEGDQEAKSLSDYSFEIPECSEILSPILNVIPLQLLAYYSAIARGCPPDQP
CCCEEEEEEECCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
RNLAKSVTVE
HHHHHHCCCC
>Mature Secondary Structure
MCGIVGYAGKKNAESVLVVGLICLEYRGYDSAGIAVLDQGDILVRKAKGKIKDLEAYLRE
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEECCCCHHHHHHHHHH
FPAPGNVGIGHTRWATHGEPNQINAHPHTDSNSTVAVVHNGIIENYLELKSELKKKGHVF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCHHH
QSLTDTEVLPHLLEESKKNGKSNKDAFLELFGKIHGKWAISTVFETEPDRVYFAQDGAPL
HHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCEEEEECCCCEE
LIGKGKGEYFLASDISPLTRNCEEVYYVSSGEWGYFSQNEFKLLDFSGKELTPVFKKQEL
EEECCCCCEEEECCCCHHHCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCCHHHHHHCC
RWEDLDKGGYPHYMIKEIHEQAGIFRKIIQERILDNGEIVFPEIKLSKDVLSRVNRIIIQ
CHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHCCHHHHHHHHHEEEE
AAGTSYYAGMIGKHYLENFAKLQTDTEASSEFRYRNPVVEGDTLIMGISQSGETADTLAS
ECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCCEEEEEECCCCCHHHHHHH
IHEAKAKFIKVVSLVNNVNSTIARESDSYIRTDAGPEIGVASTKAFTAQVLNLLLFSIYM
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ANLKWLISDEERKTLIEEIRLLPAKIDRILTQASKIERMSSHFTTAKDFIFLGRTYNHPV
HHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEECCCCCCCE
ALEGALKLKEISYIHASGYAGGEFKHGPIALITSEVPVVCIAPKSEIYTKMVSNIQEIKA
EECCCEEEEHEEEEEECCCCCCCCCCCCEEEEECCCCEEEECCHHHHHHHHHHHHHHHHH
RKGIIISIVTEGDQEAKSLSDYSFEIPECSEILSPILNVIPLQLLAYYSAIARGCPPDQP
CCCEEEEEEECCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
RNLAKSVTVE
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA