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The map label for this gene is adrA [H]

Identifier: 116329252

GI number: 116329252

Start: 3189545

End: 3190555

Strand: Reverse

Name: adrA [H]

Synonym: LBL_2691

Alternate gene names: 116329252

Gene position: 3190555-3189545 (Counterclockwise)

Preceding gene: 116329253

Following gene: 116329250

Centisome position: 88.27

GC content: 38.77

Gene sequence:

>1011_bases
ATGACCAATCCGCCGAAAGACCAAGAAACACAAATAACTATAAAAGAGCCAGAGCTGGTAAAGTTATATTCCTCCATTGG
GAAAATTATTACGTCTTCCTTGGAACAACAAGAAGTTTTAGATGCCGTCATGGAAGAAGTTCGTTTGTTTTTCAGTCCTG
AAAACTGGAGTCTTATGCGATACGATGAGAATTCCGGGGAATTATTCTTCCTAATTGCAGAAGGTCTTGAACTCAATCGT
ATCAAGAACATTCGGTTGAAGTCTGGAGAAGGAATTGCCGGTTCGGTTGTTCAAACAAAGTTGCCGATTTTCGTGGAGAA
TGTGAGAAATGACCCGAGATTTTCCAAAAGAGTCGACGAAAAAACCGGCTTTGAAACGAAAACGATCATTGCAGTTCCTA
TGATTTTCAGGGGACAAGTTTACGGAGTCATCGAATTGGTAAATCGATTTGATGGTTCCTCTTTTACTCCGGAAGATTTA
GTCATTCTTCAAACAATTGCAGACTTTACGGCAATTTCCTTGGCGCATTCCAATCAATTCGAAGAAACGAAGGTTCTCGC
GTTTCGAGATGCCTTAACGGGAGTATTTAATCGTAATAAGTTGAATCATCTTAAGAATGAATCGTCCGATAGAAGAGTAG
AGGACCGTATTGCGTTAGTTGCTCTTCTCGATTTGAATGATTTTAAAATAATCAACGACACCTACGGTCATAAGGTGGGA
GATCAAGTCCTTTGTCATTTTGCAAATGTTCTGCGTTATGTTATTCGTGGAACGGATAACATTTTTAGAATCGGAGGGGA
TGAATTTTTGATTCTTTTTCAAAATGAGAACAAGGAAAAGATCATTCAAACCCGGAAAAGATTTGAGGAAGCGATGTCGA
TTCTTTTGAGAAAATGTAAAGAGAATAATCCTCCTTTTCATTTTACTTGGGGTATGTCCGTCGGTCCCCTTCAGAAACTG
GATGAATTGATTCATGAGGCAGATCTTTCAATGTATTCTTCTAAAGATTAA

Upstream 100 bases:

>100_bases
TGATTTTATCTCAAAATGTCGTTTCAAGGAGTAATTTTTTTTGATACATAACACCTTAATTTCTTAAAATAAAAGTTTGT
ATTCGAATAGAAAAGTAATG

Downstream 100 bases:

>100_bases
AATTTTTCCGTAGTAGTCCGCGCTCAAGTTTGCTGTAAAAGAACTAGACAGATTTCCATCGTATGCCCCATTTTTTTCTA
AAAAACATGAGTTAACGTGA

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MTNPPKDQETQITIKEPELVKLYSSIGKIITSSLEQQEVLDAVMEEVRLFFSPENWSLMRYDENSGELFFLIAEGLELNR
IKNIRLKSGEGIAGSVVQTKLPIFVENVRNDPRFSKRVDEKTGFETKTIIAVPMIFRGQVYGVIELVNRFDGSSFTPEDL
VILQTIADFTAISLAHSNQFEETKVLAFRDALTGVFNRNKLNHLKNESSDRRVEDRIALVALLDLNDFKIINDTYGHKVG
DQVLCHFANVLRYVIRGTDNIFRIGGDEFLILFQNENKEKIIQTRKRFEEAMSILLRKCKENNPPFHFTWGMSVGPLQKL
DELIHEADLSMYSSKD

Sequences:

>Translated_336_residues
MTNPPKDQETQITIKEPELVKLYSSIGKIITSSLEQQEVLDAVMEEVRLFFSPENWSLMRYDENSGELFFLIAEGLELNR
IKNIRLKSGEGIAGSVVQTKLPIFVENVRNDPRFSKRVDEKTGFETKTIIAVPMIFRGQVYGVIELVNRFDGSSFTPEDL
VILQTIADFTAISLAHSNQFEETKVLAFRDALTGVFNRNKLNHLKNESSDRRVEDRIALVALLDLNDFKIINDTYGHKVG
DQVLCHFANVLRYVIRGTDNIFRIGGDEFLILFQNENKEKIIQTRKRFEEAMSILLRKCKENNPPFHFTWGMSVGPLQKL
DELIHEADLSMYSSKD
>Mature_335_residues
TNPPKDQETQITIKEPELVKLYSSIGKIITSSLEQQEVLDAVMEEVRLFFSPENWSLMRYDENSGELFFLIAEGLELNRI
KNIRLKSGEGIAGSVVQTKLPIFVENVRNDPRFSKRVDEKTGFETKTIIAVPMIFRGQVYGVIELVNRFDGSSFTPEDLV
ILQTIADFTAISLAHSNQFEETKVLAFRDALTGVFNRNKLNHLKNESSDRRVEDRIALVALLDLNDFKIINDTYGHKVGD
QVLCHFANVLRYVIRGTDNIFRIGGDEFLILFQNENKEKIIQTRKRFEEAMSILLRKCKENNPPFHFTWGMSVGPLQKLD
ELIHEADLSMYSSKD

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Homo sapiens, GI194595488, Length=157, Percent_Identity=29.2993630573248, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI5729972, Length=157, Percent_Identity=29.2993630573248, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI61744432, Length=170, Percent_Identity=31.1764705882353, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI61744430, Length=170, Percent_Identity=31.1764705882353, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI61744435, Length=170, Percent_Identity=31.1764705882353, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI4505657, Length=195, Percent_Identity=28.2051282051282, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI226246591, Length=195, Percent_Identity=28.2051282051282, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI219802706, Length=195, Percent_Identity=28.2051282051282, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1786584, Length=176, Percent_Identity=32.3863636363636, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87081881, Length=162, Percent_Identity=30.8641975308642, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1787262, Length=161, Percent_Identity=32.2981366459627, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787816, Length=150, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787541, Length=166, Percent_Identity=29.5180722891566, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081977, Length=162, Percent_Identity=28.3950617283951, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788085, Length=123, Percent_Identity=35.7723577235772, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193202333, Length=160, Percent_Identity=31.875, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 38542; Mature: 38410

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNPPKDQETQITIKEPELVKLYSSIGKIITSSLEQQEVLDAVMEEVRLFFSPENWSLMR
CCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEE
YDENSGELFFLIAEGLELNRIKNIRLKSGEGIAGSVVQTKLPIFVENVRNDPRFSKRVDE
EECCCCCEEEEEECCCCCCCCCEEEEECCCCCCCCHHHHHCCHHEECCCCCCHHHHHHHH
KTGFETKTIIAVPMIFRGQVYGVIELVNRFDGSSFTPEDLVILQTIADFTAISLAHSNQF
HCCCCCEEEEEECHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
EETKVLAFRDALTGVFNRNKLNHLKNESSDRRVEDRIALVALLDLNDFKIINDTYGHKVG
CHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHEEEEEEEECCCEEEECCCCCCHHH
DQVLCHFANVLRYVIRGTDNIFRIGGDEFLILFQNENKEKIIQTRKRFEEAMSILLRKCK
HHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
ENNPPFHFTWGMSVGPLQKLDELIHEADLSMYSSKD
CCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TNPPKDQETQITIKEPELVKLYSSIGKIITSSLEQQEVLDAVMEEVRLFFSPENWSLMR
CCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEE
YDENSGELFFLIAEGLELNRIKNIRLKSGEGIAGSVVQTKLPIFVENVRNDPRFSKRVDE
EECCCCCEEEEEECCCCCCCCCEEEEECCCCCCCCHHHHHCCHHEECCCCCCHHHHHHHH
KTGFETKTIIAVPMIFRGQVYGVIELVNRFDGSSFTPEDLVILQTIADFTAISLAHSNQF
HCCCCCEEEEEECHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
EETKVLAFRDALTGVFNRNKLNHLKNESSDRRVEDRIALVALLDLNDFKIINDTYGHKVG
CHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHEEEEEEEECCCEEEECCCCCCHHH
DQVLCHFANVLRYVIRGTDNIFRIGGDEFLILFQNENKEKIIQTRKRFEEAMSILLRKCK
HHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
ENNPPFHFTWGMSVGPLQKLDELIHEADLSMYSSKD
CCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]