| Definition | Leptospira borgpetersenii serovar Hardjo-bovis L550 chromosome 1, complete sequence. |
|---|---|
| Accession | NC_008508 |
| Length | 3,614,446 |
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The map label for this gene is lon [H]
Identifier: 116329189
GI number: 116329189
Start: 3096763
End: 3099240
Strand: Reverse
Name: lon [H]
Synonym: LBL_2617
Alternate gene names: 116329189
Gene position: 3099240-3096763 (Counterclockwise)
Preceding gene: 116329195
Following gene: 116329188
Centisome position: 85.75
GC content: 41.85
Gene sequence:
>2478_bases TTGGAGCCTTTAGAGGATTTATCGGGTATTGAAGAGAATTCAATTGTTCCATTGGACTTGATTTTACCGTCGGAACTTTT TTTAGTTCCGATTAAATCTCGACCGGTATTCCCGGGTATCATCACACCTTTAATTGTTCCTAACGGTAAGTTCGCAAAGG CCGTGGAGCAATCTCTCAAGGGAAATTCTTTTTTGGGGCTCGTTCTTTTGAAGGACGAGGAAAATGAAAAGGAAACTTCC GAAAACATCTATCAGTTCGGCGTCGTCGCTAAAATTTTAAAAAAGGTACATTTACCTGATGATGCGGTCAATATTCTCAT CAATACGATTTGTCGTTTTAAAATCGATTCCTATAACAGTAAAGATCCGTTGATTGCCAAGGTCTCCTATCCGGAGGAGG AACCTGGAGCGCCGAAAAACACGATCAAAGCAATGATGAGAACCTTACTTGTCATGACGAGAGAACTTGCACAAAACAAT CCGCTATTTACGGAAGAAATGAAACTTACCATGTTGAACGTAAATGAGCCTGGGAAGATGGCGGACTTTGTCTGTTCTAT TCTTAACCTGGAAAAAGAAGAATATCAATCCGTCATCGAATCTAATATTCTTAAGGAGAGAATCGAAAAGGTTCTTCTCT TTTTAAAGAAAGAGATCGAACTCGTATCCATTCAAAGGGAAATTTCCGATCAAATCCAAGACAAAATCGACAAACAACAA AGACAATTCTTTTTACGAGAACAACTCAAGGCGATACAGAACGAACTCGGGATCAAGGATGATAATTTCGAAAAAAAATA CGAAAAATTTCTGGAACGACTGAAATCCATCGGTGCGGATACCGAGGTCATTGAGGAGGTAAGCAGAGAATTGGATAAGT TCTCTTATGCAGATCCGAATACCGGAGATTATAACGTTATCCGAAATTACTTGGACATTCTAGAATCCCTCCCTTGGGAG CCTGCACCCGCAAGAGAAATCGATTTGGACAAGGCCAAAAAAACCCTGGACAGAGATCATTATAAACTCGAGGACGTGAA GGATAGGATCTTGGAGTTCCTCGCTGTCAAAAAATTGAAAAGCGATGAAAAAGGAACGATTCTTTTATTAGTCGGCCCTC CGGGTGTAGGGAAAACTTCGATTGCGAGGTCCATTGCCGAAGCTATGGGAAGAAAATTTTTTCGATTCTCCGTCGGAGGA ATGAGGGACGAGGCCGAAATCAAGGGTCATCGAAGAACCTACATCGGTTCTATGCCCGGTAAAATTATTTCCGCTCTTAG GATCACAAAGGAAAAAGATTGCGTTATCTTGCTTGACGAGATCGATAAACTTGCAACAGGCATTCAAGGGGATCCGGCTT CCGCTTTTTTGGAAGTTTTGGATCCGGAACAAAATAAGAATTTCAGGGATCATTATCTGGACCTTCCATTCGATATTTCG AATGTGTTTTTTATAGCGACCGCCAATACGTTGGATTCCATCTCCAGGATTCTTTTGGATCGGATGGAAATTATTAATCT TTCGGGTTATATTACGGACGAAAAAGTGCAAATCTTTCAGAGATACCTTTGGAAAAAGGTTCTTGCGAAAAACGGGGTAA CTTCTTACGGAATTGAGTTCGATAAAAAAGCGGTGGTTTCTTTGATCGATTCTTATTCGAGAGAATCCGGAGTTCGCGGT TTGGAAAAGGTTACTGATAAGCTTGTTCGTAAGATTGCGATGAAAATCGTAAAGAAGGAGCCCTTCCCGAAAGTTATTCT AGAAAAAGATCTTGAAACGTTTTTAGGAGTGCCAAAGTTTACGAACGAAAGAATGATTCGTACCTCGGTTCCTGGTACCG CGCTCGGTCTTGCGTGGACTTCTGTCGGAGGAGCGACACTTCTTATAGAAGCTCTTTTTGTAAAAGGAAAGGGAGGAATT CTTCTTACCGGGATGATCGGAAAAACGATGGAGGAATCCTCGAACATCGCTTTGAGTTATATTAAGAATTTTTTAAGTAA GGACGAATTGTTCAAAGATCAGATGATACATTTGCACGTTCCGGATGGGGCGACTCCGAAAGACGGTCCTTCTGCGGGAA TCACAATGGCGACCGCGATCCTTTCCCTTGCCTTGAATACAAAAGTGAAGGCGGGCTACGGGATGACCGGGGAACTCACT CTTACGGGGGAAGTTCTTGCGATTGGGGGCTTACGTGAAAAGATCGTAGCGGCAAAAAGAGTCGGAATTTATAAAATCAT TTATCCAAAAGACAATCTCCAGCATCTGGAGGAAATTCCGGACTATGTAAAAAAAGGAATGTCTTTTTTTCCGGTCAGTC GCTATGAGGAAGTTGCCGCGATGGTGTTCGACGAAAAGGTTCTTCTGAAAGTAAATCCTTCTTTTAAGGAGAGCTTAAAG TTGATCACAACTTCGGCAGGAAAAACGGCTCCGAAAAAAAAGACGGTATCCAAAAAAAGAACGACTTCTTCGAAGTAG
Upstream 100 bases:
>100_bases GGCACAAAATGGATCGGATTTGATTTGAGAATCTCTTCCCGGTATAAGAACCTGGACAAAATCCGGTTCTCCGGAATGTT TTCAGATTTAAGGAGGTCTT
Downstream 100 bases:
>100_bases AGGGTCGACTCGAAAAGAGTGACATATTTTAGAATGTTATTATATACAAATTTAGAATTCAGGAGAGCCGAATGGGCGTT CCATTTATCGATATCAAAAG
Product: endopeptidase La
Products: NA
Alternate protein names: ATP-dependent protease La [H]
Number of amino acids: Translated: 825; Mature: 825
Protein sequence:
>825_residues MEPLEDLSGIEENSIVPLDLILPSELFLVPIKSRPVFPGIITPLIVPNGKFAKAVEQSLKGNSFLGLVLLKDEENEKETS ENIYQFGVVAKILKKVHLPDDAVNILINTICRFKIDSYNSKDPLIAKVSYPEEEPGAPKNTIKAMMRTLLVMTRELAQNN PLFTEEMKLTMLNVNEPGKMADFVCSILNLEKEEYQSVIESNILKERIEKVLLFLKKEIELVSIQREISDQIQDKIDKQQ RQFFLREQLKAIQNELGIKDDNFEKKYEKFLERLKSIGADTEVIEEVSRELDKFSYADPNTGDYNVIRNYLDILESLPWE PAPAREIDLDKAKKTLDRDHYKLEDVKDRILEFLAVKKLKSDEKGTILLLVGPPGVGKTSIARSIAEAMGRKFFRFSVGG MRDEAEIKGHRRTYIGSMPGKIISALRITKEKDCVILLDEIDKLATGIQGDPASAFLEVLDPEQNKNFRDHYLDLPFDIS NVFFIATANTLDSISRILLDRMEIINLSGYITDEKVQIFQRYLWKKVLAKNGVTSYGIEFDKKAVVSLIDSYSRESGVRG LEKVTDKLVRKIAMKIVKKEPFPKVILEKDLETFLGVPKFTNERMIRTSVPGTALGLAWTSVGGATLLIEALFVKGKGGI LLTGMIGKTMEESSNIALSYIKNFLSKDELFKDQMIHLHVPDGATPKDGPSAGITMATAILSLALNTKVKAGYGMTGELT LTGEVLAIGGLREKIVAAKRVGIYKIIYPKDNLQHLEEIPDYVKKGMSFFPVSRYEEVAAMVFDEKVLLKVNPSFKESLK LITTSAGKTAPKKKTVSKKRTTSSK
Sequences:
>Translated_825_residues MEPLEDLSGIEENSIVPLDLILPSELFLVPIKSRPVFPGIITPLIVPNGKFAKAVEQSLKGNSFLGLVLLKDEENEKETS ENIYQFGVVAKILKKVHLPDDAVNILINTICRFKIDSYNSKDPLIAKVSYPEEEPGAPKNTIKAMMRTLLVMTRELAQNN PLFTEEMKLTMLNVNEPGKMADFVCSILNLEKEEYQSVIESNILKERIEKVLLFLKKEIELVSIQREISDQIQDKIDKQQ RQFFLREQLKAIQNELGIKDDNFEKKYEKFLERLKSIGADTEVIEEVSRELDKFSYADPNTGDYNVIRNYLDILESLPWE PAPAREIDLDKAKKTLDRDHYKLEDVKDRILEFLAVKKLKSDEKGTILLLVGPPGVGKTSIARSIAEAMGRKFFRFSVGG MRDEAEIKGHRRTYIGSMPGKIISALRITKEKDCVILLDEIDKLATGIQGDPASAFLEVLDPEQNKNFRDHYLDLPFDIS NVFFIATANTLDSISRILLDRMEIINLSGYITDEKVQIFQRYLWKKVLAKNGVTSYGIEFDKKAVVSLIDSYSRESGVRG LEKVTDKLVRKIAMKIVKKEPFPKVILEKDLETFLGVPKFTNERMIRTSVPGTALGLAWTSVGGATLLIEALFVKGKGGI LLTGMIGKTMEESSNIALSYIKNFLSKDELFKDQMIHLHVPDGATPKDGPSAGITMATAILSLALNTKVKAGYGMTGELT LTGEVLAIGGLREKIVAAKRVGIYKIIYPKDNLQHLEEIPDYVKKGMSFFPVSRYEEVAAMVFDEKVLLKVNPSFKESLK LITTSAGKTAPKKKTVSKKRTTSSK >Mature_825_residues MEPLEDLSGIEENSIVPLDLILPSELFLVPIKSRPVFPGIITPLIVPNGKFAKAVEQSLKGNSFLGLVLLKDEENEKETS ENIYQFGVVAKILKKVHLPDDAVNILINTICRFKIDSYNSKDPLIAKVSYPEEEPGAPKNTIKAMMRTLLVMTRELAQNN PLFTEEMKLTMLNVNEPGKMADFVCSILNLEKEEYQSVIESNILKERIEKVLLFLKKEIELVSIQREISDQIQDKIDKQQ RQFFLREQLKAIQNELGIKDDNFEKKYEKFLERLKSIGADTEVIEEVSRELDKFSYADPNTGDYNVIRNYLDILESLPWE PAPAREIDLDKAKKTLDRDHYKLEDVKDRILEFLAVKKLKSDEKGTILLLVGPPGVGKTSIARSIAEAMGRKFFRFSVGG MRDEAEIKGHRRTYIGSMPGKIISALRITKEKDCVILLDEIDKLATGIQGDPASAFLEVLDPEQNKNFRDHYLDLPFDIS NVFFIATANTLDSISRILLDRMEIINLSGYITDEKVQIFQRYLWKKVLAKNGVTSYGIEFDKKAVVSLIDSYSRESGVRG LEKVTDKLVRKIAMKIVKKEPFPKVILEKDLETFLGVPKFTNERMIRTSVPGTALGLAWTSVGGATLLIEALFVKGKGGI LLTGMIGKTMEESSNIALSYIKNFLSKDELFKDQMIHLHVPDGATPKDGPSAGITMATAILSLALNTKVKAGYGMTGELT LTGEVLAIGGLREKIVAAKRVGIYKIIYPKDNLQHLEEIPDYVKKGMSFFPVSRYEEVAAMVFDEKVLLKVNPSFKESLK LITTSAGKTAPKKKTVSKKRTTSSK
Specific function: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced
COG id: COG0466
COG function: function code O; ATP-dependent Lon protease, bacterial type
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 Lon domain [H]
Homologues:
Organism=Homo sapiens, GI21396489, Length=832, Percent_Identity=39.1826923076923, Blast_Score=576, Evalue=1e-164, Organism=Homo sapiens, GI31377667, Length=864, Percent_Identity=33.2175925925926, Blast_Score=453, Evalue=1e-127, Organism=Escherichia coli, GI1786643, Length=765, Percent_Identity=39.4771241830065, Blast_Score=555, Evalue=1e-159, Organism=Caenorhabditis elegans, GI17505831, Length=702, Percent_Identity=38.6039886039886, Blast_Score=506, Evalue=1e-143, Organism=Caenorhabditis elegans, GI17556486, Length=549, Percent_Identity=39.7085610200364, Blast_Score=426, Evalue=1e-119, Organism=Saccharomyces cerevisiae, GI6319449, Length=725, Percent_Identity=41.5172413793103, Blast_Score=547, Evalue=1e-156, Organism=Drosophila melanogaster, GI221513036, Length=664, Percent_Identity=44.8795180722892, Blast_Score=560, Evalue=1e-159, Organism=Drosophila melanogaster, GI24666867, Length=664, Percent_Identity=44.8795180722892, Blast_Score=559, Evalue=1e-159,
Paralogues:
None
Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003593 - InterPro: IPR003959 - InterPro: IPR008269 - InterPro: IPR004815 - InterPro: IPR003111 - InterPro: IPR008268 - InterPro: IPR001984 - InterPro: IPR015947 - InterPro: IPR020568 [H]
Pfam domain/function: PF00004 AAA; PF02190 LON; PF05362 Lon_C [H]
EC number: =3.4.21.53 [H]
Molecular weight: Translated: 92673; Mature: 92673
Theoretical pI: Translated: 8.54; Mature: 8.54
Prosite motif: PS01046 LON_SER
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MEPLEDLSGIEENSIVPLDLILPSELFLVPIKSRPVFPGIITPLIVPNGKFAKAVEQSLK CCCHHHHCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCHHHHHCCCCCHHHHHHHHHCC GNSFLGLVLLKDEENEKETSENIYQFGVVAKILKKVHLPDDAVNILINTICRFKIDSYNS CCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEECCCCC KDPLIAKVSYPEEEPGAPKNTIKAMMRTLLVMTRELAQNNPLFTEEMKLTMLNVNEPGKM CCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEECCEEEEEEECCCCCHH ADFVCSILNLEKEEYQSVIESNILKERIEKVLLFLKKEIELVSIQREISDQIQDKIDKQQ HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH RQFFLREQLKAIQNELGIKDDNFEKKYEKFLERLKSIGADTEVIEEVSRELDKFSYADPN HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCC TGDYNVIRNYLDILESLPWEPAPAREIDLDKAKKTLDRDHYKLEDVKDRILEFLAVKKLK CCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHC SDEKGTILLLVGPPGVGKTSIARSIAEAMGRKFFRFSVGGMRDEAEIKGHRRTYIGSMPG CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHEEHHHCCCCCCHHHHCCCHHHHCCCCCH KIISALRITKEKDCVILLDEIDKLATGIQGDPASAFLEVLDPEQNKNFRDHYLDLPFDIS HHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHCCCCCCCC NVFFIATANTLDSISRILLDRMEIINLSGYITDEKVQIFQRYLWKKVLAKNGVTSYGIEF CEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC DKKAVVSLIDSYSRESGVRGLEKVTDKLVRKIAMKIVKKEPFPKVILEKDLETFLGVPKF HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCC TNERMIRTSVPGTALGLAWTSVGGATLLIEALFVKGKGGILLTGMIGKTMEESSNIALSY CCCCEEEECCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEHHCCHHHHCCCHHHHH IKNFLSKDELFKDQMIHLHVPDGATPKDGPSAGITMATAILSLALNTKVKAGYGMTGELT HHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCEECCCCCCEEEE LTGEVLAIGGLREKIVAAKRVGIYKIIYPKDNLQHLEEIPDYVKKGMSFFPVSRYEEVAA ECCCEEEECCHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHH MVFDEKVLLKVNPSFKESLKLITTSAGKTAPKKKTVSKKRTTSSK HHHCCEEEEEECCCHHHHHHHHEECCCCCCCCHHHHHHHHCCCCC >Mature Secondary Structure MEPLEDLSGIEENSIVPLDLILPSELFLVPIKSRPVFPGIITPLIVPNGKFAKAVEQSLK CCCHHHHCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCHHHHHCCCCCHHHHHHHHHCC GNSFLGLVLLKDEENEKETSENIYQFGVVAKILKKVHLPDDAVNILINTICRFKIDSYNS CCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEECCCCC KDPLIAKVSYPEEEPGAPKNTIKAMMRTLLVMTRELAQNNPLFTEEMKLTMLNVNEPGKM CCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEECCEEEEEEECCCCCHH ADFVCSILNLEKEEYQSVIESNILKERIEKVLLFLKKEIELVSIQREISDQIQDKIDKQQ HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH RQFFLREQLKAIQNELGIKDDNFEKKYEKFLERLKSIGADTEVIEEVSRELDKFSYADPN HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCC TGDYNVIRNYLDILESLPWEPAPAREIDLDKAKKTLDRDHYKLEDVKDRILEFLAVKKLK CCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHC SDEKGTILLLVGPPGVGKTSIARSIAEAMGRKFFRFSVGGMRDEAEIKGHRRTYIGSMPG CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHEEHHHCCCCCCHHHHCCCHHHHCCCCCH KIISALRITKEKDCVILLDEIDKLATGIQGDPASAFLEVLDPEQNKNFRDHYLDLPFDIS HHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHCCCCCCCC NVFFIATANTLDSISRILLDRMEIINLSGYITDEKVQIFQRYLWKKVLAKNGVTSYGIEF CEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC DKKAVVSLIDSYSRESGVRGLEKVTDKLVRKIAMKIVKKEPFPKVILEKDLETFLGVPKF HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCC TNERMIRTSVPGTALGLAWTSVGGATLLIEALFVKGKGGILLTGMIGKTMEESSNIALSY CCCCEEEECCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEHHCCHHHHCCCHHHHH IKNFLSKDELFKDQMIHLHVPDGATPKDGPSAGITMATAILSLALNTKVKAGYGMTGELT HHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCEECCCCCCEEEE LTGEVLAIGGLREKIVAAKRVGIYKIIYPKDNLQHLEEIPDYVKKGMSFFPVSRYEEVAA ECCCEEEECCHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHH MVFDEKVLLKVNPSFKESLKLITTSAGKTAPKKKTVSKKRTTSSK HHHCCEEEEEECCCHHHHHHHHEECCCCCCCCHHHHHHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA