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The map label for this gene is murC-1 [H]

Identifier: 116329177

GI number: 116329177

Start: 3079625

End: 3081208

Strand: Direct

Name: murC-1 [H]

Synonym: LBL_2604

Alternate gene names: 116329177

Gene position: 3079625-3081208 (Clockwise)

Preceding gene: 116329176

Following gene: 116329179

Centisome position: 85.2

GC content: 43.75

Gene sequence:

>1584_bases
ATGAGTTTAAACAGATTGTCCTTTCAAAAACCGTTCTTTCTAGGAATCGGCGGTTCCGGCATGTCCTCTCTCGCATTTTT
ACTTTTGAGTAAGGGGCTTAAAGTCGGAGGCTACGACGGAAAACATTCAGCGGTCGTGGAAAAACTGGTTTTAAACGGCG
CAACCGTGCTACATAAATCCGACGTTTTAGAAGTGGAGAATTACGATCTCGCGGTTTATTCTTCCGCGATCCGGTTGGAG
TCTCATCCTTTGGTGAAAAAATTCAAAGACAAGGGAATTCCTTTAGTGCATCGGTCGGAACTACTTCATCAGGTCATGTC
GGAAAAAAAACAAATTTCCGTCGCGGGTTCCCACGGTAAAACGACGACGAGCGCTATGATCGCATTCCTGCTGGAAAAAT
GCGGGATGTCACCGTCTATCATGGTTGGAGGAGAAGTCGCATTTTTGGACGGTAAAGGCGGTTCCTGGGGAAAAGGAGAA
TGGGGAATCTTCGAATCGGACGAATCGGACGGAACATTCAACAATCATAATGCGGAAATCCGGGTTCTTACCAATGTGGA
TGAAGATCATTTGGATCATTATCTGACTCGGGAGAATCTCCTGAGCGCTTTTGCACGTTACATGGAGCGTACCTCTTGGA
AATTGATCCTGAATTTAGACGACATCGGAATCCGGGATTCTCTCGCGCTGATCCAAGACCATTCTAAAATATTAGGATTT
TGTAAAGTTTTTGTTTCCGGCGAAATCGCAAAGAACCCTTCACACAATTCAAATGTTGAAGGAACTCGCACAACGGATTC
AAGTTCTGCAGGAAACAGAGTAATTTCATCTAACTTAGAAAAAAAAACGTCACAGATCGGGGAAAAAAGCATTTCGCAAT
ACTCAAAAGGGAAAGTTTCAAAAATTGAAACGTTCGGCGCTCAAGACGATACGACAAACGACGTCTTACGGGATATCGAT
TCTTCTAAAATCATATATTACACGATCGAGTCCGGCAATCTTAGTTTTCGATTTCAAGAAAAGGAATATTCCTTTTTCCT
TAAGTATCCGGGCGAACACTATTTAAAAAACGCTTTGGCTGCGATTCTGGCCTGTTCCGAGGCGGGTGCGCCCGTTACGG
AACTCGTTTCTCAAATTTCGGAATACTCCGGTGTCAGCAGAAGACTCGAATATTTAGGTAGCAAAAACGGTATCGAGGTC
TATGACGATTACGGACACCATCCTACGGAAATCAAGGCGGTGATTCAGTCCATGGAAGGTCTGAAAAAAAACGGAAGGGC
AATCATTCTTTTCCAACCCCATCGATATACTCGGACGCAAAATCTTTATAAGGAATTCGCCGAAAGTCTGGATACCGGAG
AATCGGTGTATCTTTTACCGATCTACCCCGCAGGAGAAGATCCGATCGAGGGCGTGGGAACGGAACTCATTCTGAATTCT
ATGAAAGTTTCCGCAAAAATTCTCCCCAAAGAAATTTCCGATGGAATTTTCATATTGAAAAATTCTCTGAAACCCGGAGA
CAAACTCATCACTTTAGGAGCCGGTAACGTAAGAGATTGGGGGATCGCTTTTTTAAAAGATTAA

Upstream 100 bases:

>100_bases
ACGTAAATCTGTTAAACGACATGTCCATCAGTTCTCTTCAGTGCTCCCACGTGGATGCTTCCAAAGACACGGTGAAATAT
TTTTTCTCTCTCGATTGATG

Downstream 100 bases:

>100_bases
TTACATAAAAGAACTCGTATACAATCGACACGAGTTAGATACAATTAAAATAGAATATTAAAATATTTTAATTCAAGGAA
TCGATCCTAAATTGAAGGTC

Product: UDP-N-acetylmuramate--L-alanine ligase

Products: NA

Alternate protein names: UDP-N-acetylmuramoyl-L-alanine synthetase [H]

Number of amino acids: Translated: 527; Mature: 526

Protein sequence:

>527_residues
MSLNRLSFQKPFFLGIGGSGMSSLAFLLLSKGLKVGGYDGKHSAVVEKLVLNGATVLHKSDVLEVENYDLAVYSSAIRLE
SHPLVKKFKDKGIPLVHRSELLHQVMSEKKQISVAGSHGKTTTSAMIAFLLEKCGMSPSIMVGGEVAFLDGKGGSWGKGE
WGIFESDESDGTFNNHNAEIRVLTNVDEDHLDHYLTRENLLSAFARYMERTSWKLILNLDDIGIRDSLALIQDHSKILGF
CKVFVSGEIAKNPSHNSNVEGTRTTDSSSAGNRVISSNLEKKTSQIGEKSISQYSKGKVSKIETFGAQDDTTNDVLRDID
SSKIIYYTIESGNLSFRFQEKEYSFFLKYPGEHYLKNALAAILACSEAGAPVTELVSQISEYSGVSRRLEYLGSKNGIEV
YDDYGHHPTEIKAVIQSMEGLKKNGRAIILFQPHRYTRTQNLYKEFAESLDTGESVYLLPIYPAGEDPIEGVGTELILNS
MKVSAKILPKEISDGIFILKNSLKPGDKLITLGAGNVRDWGIAFLKD

Sequences:

>Translated_527_residues
MSLNRLSFQKPFFLGIGGSGMSSLAFLLLSKGLKVGGYDGKHSAVVEKLVLNGATVLHKSDVLEVENYDLAVYSSAIRLE
SHPLVKKFKDKGIPLVHRSELLHQVMSEKKQISVAGSHGKTTTSAMIAFLLEKCGMSPSIMVGGEVAFLDGKGGSWGKGE
WGIFESDESDGTFNNHNAEIRVLTNVDEDHLDHYLTRENLLSAFARYMERTSWKLILNLDDIGIRDSLALIQDHSKILGF
CKVFVSGEIAKNPSHNSNVEGTRTTDSSSAGNRVISSNLEKKTSQIGEKSISQYSKGKVSKIETFGAQDDTTNDVLRDID
SSKIIYYTIESGNLSFRFQEKEYSFFLKYPGEHYLKNALAAILACSEAGAPVTELVSQISEYSGVSRRLEYLGSKNGIEV
YDDYGHHPTEIKAVIQSMEGLKKNGRAIILFQPHRYTRTQNLYKEFAESLDTGESVYLLPIYPAGEDPIEGVGTELILNS
MKVSAKILPKEISDGIFILKNSLKPGDKLITLGAGNVRDWGIAFLKD
>Mature_526_residues
SLNRLSFQKPFFLGIGGSGMSSLAFLLLSKGLKVGGYDGKHSAVVEKLVLNGATVLHKSDVLEVENYDLAVYSSAIRLES
HPLVKKFKDKGIPLVHRSELLHQVMSEKKQISVAGSHGKTTTSAMIAFLLEKCGMSPSIMVGGEVAFLDGKGGSWGKGEW
GIFESDESDGTFNNHNAEIRVLTNVDEDHLDHYLTRENLLSAFARYMERTSWKLILNLDDIGIRDSLALIQDHSKILGFC
KVFVSGEIAKNPSHNSNVEGTRTTDSSSAGNRVISSNLEKKTSQIGEKSISQYSKGKVSKIETFGAQDDTTNDVLRDIDS
SKIIYYTIESGNLSFRFQEKEYSFFLKYPGEHYLKNALAAILACSEAGAPVTELVSQISEYSGVSRRLEYLGSKNGIEVY
DDYGHHPTEIKAVIQSMEGLKKNGRAIILFQPHRYTRTQNLYKEFAESLDTGESVYLLPIYPAGEDPIEGVGTELILNSM
KVSAKILPKEISDGIFILKNSLKPGDKLITLGAGNVRDWGIAFLKD

Specific function: Cell wall formation [H]

COG id: COG0773

COG function: function code M; UDP-N-acetylmuramate-alanine ligase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MurCDEF family [H]

Homologues:

Organism=Escherichia coli, GI1790680, Length=458, Percent_Identity=26.6375545851528, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1786279, Length=200, Percent_Identity=33, Blast_Score=105, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004101
- InterPro:   IPR013221
- InterPro:   IPR000713
- InterPro:   IPR016040
- InterPro:   IPR005758 [H]

Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]

EC number: =6.3.2.8 [H]

Molecular weight: Translated: 58059; Mature: 57927

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS00284 SERPIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNRLSFQKPFFLGIGGSGMSSLAFLLLSKGLKVGGYDGKHSAVVEKLVLNGATVLHKS
CCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHCCCCEEECC
DVLEVENYDLAVYSSAIRLESHPLVKKFKDKGIPLVHRSELLHQVMSEKKQISVAGSHGK
CCEEECCCCEEEEEEEHEECCCHHHHHHHHCCCCEEHHHHHHHHHHCCCCEEEEECCCCC
TTTSAMIAFLLEKCGMSPSIMVGGEVAFLDGKGGSWGKGEWGIFESDESDGTFNNHNAEI
HHHHHHHHHHHHHHCCCCCEEECCEEEEEECCCCCCCCCCCCEEECCCCCCCCCCCCCEE
RVLTNVDEDHLDHYLTRENLLSAFARYMERTSWKLILNLDDIGIRDSLALIQDHSKILGF
EEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHH
CKVFVSGEIAKNPSHNSNVEGTRTTDSSSAGNRVISSNLEKKTSQIGEKSISQYSKGKVS
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCH
KIETFGAQDDTTNDVLRDIDSSKIIYYTIESGNLSFRFQEKEYSFFLKYPGEHYLKNALA
HHHCCCCCCCCHHHHHHHCCCCEEEEEEEECCCEEEEEECCCEEEEEECCCHHHHHHHHH
AILACSEAGAPVTELVSQISEYSGVSRRLEYLGSKNGIEVYDDYGHHPTEIKAVIQSMEG
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHH
LKKNGRAIILFQPHRYTRTQNLYKEFAESLDTGESVYLLPIYPAGEDPIEGVGTELILNS
HHHCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHCCHHHHHHH
MKVSAKILPKEISDGIFILKNSLKPGDKLITLGAGNVRDWGIAFLKD
HHHHHHCCCHHHCCCEEEEECCCCCCCEEEEECCCCCCCCCEEEECC
>Mature Secondary Structure 
SLNRLSFQKPFFLGIGGSGMSSLAFLLLSKGLKVGGYDGKHSAVVEKLVLNGATVLHKS
CCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHCCCCEEECC
DVLEVENYDLAVYSSAIRLESHPLVKKFKDKGIPLVHRSELLHQVMSEKKQISVAGSHGK
CCEEECCCCEEEEEEEHEECCCHHHHHHHHCCCCEEHHHHHHHHHHCCCCEEEEECCCCC
TTTSAMIAFLLEKCGMSPSIMVGGEVAFLDGKGGSWGKGEWGIFESDESDGTFNNHNAEI
HHHHHHHHHHHHHHCCCCCEEECCEEEEEECCCCCCCCCCCCEEECCCCCCCCCCCCCEE
RVLTNVDEDHLDHYLTRENLLSAFARYMERTSWKLILNLDDIGIRDSLALIQDHSKILGF
EEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHH
CKVFVSGEIAKNPSHNSNVEGTRTTDSSSAGNRVISSNLEKKTSQIGEKSISQYSKGKVS
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCH
KIETFGAQDDTTNDVLRDIDSSKIIYYTIESGNLSFRFQEKEYSFFLKYPGEHYLKNALA
HHHCCCCCCCCHHHHHHHCCCCEEEEEEEECCCEEEEEECCCEEEEEECCCHHHHHHHHH
AILACSEAGAPVTELVSQISEYSGVSRRLEYLGSKNGIEVYDDYGHHPTEIKAVIQSMEG
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHH
LKKNGRAIILFQPHRYTRTQNLYKEFAESLDTGESVYLLPIYPAGEDPIEGVGTELILNS
HHHCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHCCHHHHHHH
MKVSAKILPKEISDGIFILKNSLKPGDKLITLGAGNVRDWGIAFLKD
HHHHHHCCCHHHCCCEEEEECCCCCCCEEEEECCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA