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The map label for this gene is murG

Identifier: 116329176

GI number: 116329176

Start: 3078546

End: 3079622

Strand: Direct

Name: murG

Synonym: LBL_2603

Alternate gene names: 116329176

Gene position: 3078546-3079622 (Clockwise)

Preceding gene: 116329175

Following gene: 116329177

Centisome position: 85.17

GC content: 42.34

Gene sequence:

>1077_bases
ATGAGATCGATCGTAATCGCGGCCGGCGGAACCGGGGGACATATTTCCCCGGGGGTGGCTCTGGCGGAAGTATTAACCGA
CTTGAAAGAAAAGATAGGATACGAAAACTTATATTTATACTCCTTGATCCGCAATCAAAACAATCCGGATTTAGAACAAG
CTCCTTGTCCGGTTCTGTGGCATAACCTTCCGCCACTTTCGAGTAACATTTTTCTATTTCCTTTTCGTTATACGATTCAG
ATTTTAAAAACGTTTCTTTTATTCAAAAAATTGAATGTAGACGTAGTAATCGGAATGGGAGGTTATTCCACCGTATCTTC
CATACTTTACGGGATCCTTTTTAAAAAGAAAATCTATCTTTGCGAACAAAACACCGTCCCCGGAAACGTGAGCCGATTGT
TCTTTCGATTTGCGAACAAAGCCGCTTTTAGTTTTCCGCCGAAAAATTCCGCGATCCCCTGTGATTATCAAGTTCTCGGA
AATCCGCTCAGAAAAAAAACGCTTCCTAAAATGTCTTTGAAGTTCTCCGAAAAATACGACACCAAAAAGAAAACACAATT
CAACGTGCTTGTGATGGGCGGAAGTCAAGGAGCGAGACAGATCAACAATATCGTCATTGCATTGATGGGGCACGAGGAAA
TCAATATTCAGTTTCGATTTCGAGTATTAACCGGTTCCGCGTTATACGAGGAGGTTTCCAAAAAAACGAAAAAAGATGCC
GAACTTATTTCTTATTCCGATAACATGAAAGAACACTACGAATGGGCAAACTTCGTGATCGCCCGCGCGGGTTCGGGCGT
CCTTTCCGAGTGTGCAGCGTTCGCATTACCTATGATTTTGATTCCTTATCCGTACGCGAAAGACGATCACCAAATGGCAA
ACGCAAGATATTTAGAACTCAACGGGGCCGCAATCGTAATCGATCAAAAGGACGAGGACGAATCCCATCTTTTCAAAGTT
TTAGATCAAATTGCAAATAACGTAAATCTGTTAAACGACATGTCCATCAGTTCTCTTCAGTGCTCCCACGTGGATGCTTC
CAAAGACACGGTGAAATATTTTTTCTCTCTCGATTGA

Upstream 100 bases:

>100_bases
TCAGTTTGCCGTTCGTGAGTTACGGAGGATCGTCAATTCTCATCGTACTGATTTCTCTTGGAATTCTTGTCAATATTACG
CGAAAGGAAAACTTGGGATT

Downstream 100 bases:

>100_bases
TGATGAGTTTAAACAGATTGTCCTTTCAAAAACCGTTCTTTCTAGGAATCGGCGGTTCCGGCATGTCCTCTCTCGCATTT
TTACTTTTGAGTAAGGGGCT

Product: undecaprenyldiphospho-muramoylpentapeptide beta- N-acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MRSIVIAAGGTGGHISPGVALAEVLTDLKEKIGYENLYLYSLIRNQNNPDLEQAPCPVLWHNLPPLSSNIFLFPFRYTIQ
ILKTFLLFKKLNVDVVIGMGGYSTVSSILYGILFKKKIYLCEQNTVPGNVSRLFFRFANKAAFSFPPKNSAIPCDYQVLG
NPLRKKTLPKMSLKFSEKYDTKKKTQFNVLVMGGSQGARQINNIVIALMGHEEINIQFRFRVLTGSALYEEVSKKTKKDA
ELISYSDNMKEHYEWANFVIARAGSGVLSECAAFALPMILIPYPYAKDDHQMANARYLELNGAAIVIDQKDEDESHLFKV
LDQIANNVNLLNDMSISSLQCSHVDASKDTVKYFFSLD

Sequences:

>Translated_358_residues
MRSIVIAAGGTGGHISPGVALAEVLTDLKEKIGYENLYLYSLIRNQNNPDLEQAPCPVLWHNLPPLSSNIFLFPFRYTIQ
ILKTFLLFKKLNVDVVIGMGGYSTVSSILYGILFKKKIYLCEQNTVPGNVSRLFFRFANKAAFSFPPKNSAIPCDYQVLG
NPLRKKTLPKMSLKFSEKYDTKKKTQFNVLVMGGSQGARQINNIVIALMGHEEINIQFRFRVLTGSALYEEVSKKTKKDA
ELISYSDNMKEHYEWANFVIARAGSGVLSECAAFALPMILIPYPYAKDDHQMANARYLELNGAAIVIDQKDEDESHLFKV
LDQIANNVNLLNDMSISSLQCSHVDASKDTVKYFFSLD
>Mature_358_residues
MRSIVIAAGGTGGHISPGVALAEVLTDLKEKIGYENLYLYSLIRNQNNPDLEQAPCPVLWHNLPPLSSNIFLFPFRYTIQ
ILKTFLLFKKLNVDVVIGMGGYSTVSSILYGILFKKKIYLCEQNTVPGNVSRLFFRFANKAAFSFPPKNSAIPCDYQVLG
NPLRKKTLPKMSLKFSEKYDTKKKTQFNVLVMGGSQGARQINNIVIALMGHEEINIQFRFRVLTGSALYEEVSKKTKKDA
ELISYSDNMKEHYEWANFVIARAGSGVLSECAAFALPMILIPYPYAKDDHQMANARYLELNGAAIVIDQKDEDESHLFKV
LDQIANNVNLLNDMSISSLQCSHVDASKDTVKYFFSLD

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=329, Percent_Identity=29.1793313069909, Blast_Score=115, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_LEPBJ (Q04V94)

Other databases:

- EMBL:   CP000350
- RefSeq:   YP_799934.1
- ProteinModelPortal:   Q04V94
- SMR:   Q04V94
- STRING:   Q04V94
- GeneID:   4409376
- GenomeReviews:   CP000350_GR
- KEGG:   lbj:LBJ_0476
- eggNOG:   COG0707
- HOGENOM:   HBG529373
- OMA:   PHGNGEQ
- ProtClustDB:   CLSK574171
- BioCyc:   LBOR355277:LBJ_0476-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 40207; Mature: 40207

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSIVIAAGGTGGHISPGVALAEVLTDLKEKIGYENLYLYSLIRNQNNPDLEQAPCPVLW
CCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHCCCCEEE
HNLPPLSSNIFLFPFRYTIQILKTFLLFKKLNVDVVIGMGGYSTVSSILYGILFKKKIYL
CCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHEEEE
CEQNTVPGNVSRLFFRFANKAAFSFPPKNSAIPCDYQVLGNPLRKKTLPKMSLKFSEKYD
EECCCCCCHHHHHHHHHHCCCEEECCCCCCCCCCCHHHHCCHHHHHCCCCHHEEECHHCC
TKKKTQFNVLVMGGSQGARQINNIVIALMGHEEINIQFRFRVLTGSALYEEVSKKTKKDA
CCCCCEEEEEEEECCCCHHHHCCEEEEEECCCEEEEEEEEEEEECHHHHHHHHHHHHCCH
ELISYSDNMKEHYEWANFVIARAGSGVLSECAAFALPMILIPYPYAKDDHQMANARYLEL
HHHHCCCCHHHHHHHHHEEEEECCCCHHHHHHHHHCCHHEECCCCCCCCCHHCCEEEEEE
NGAAIVIDQKDEDESHLFKVLDQIANNVNLLNDMSISSLQCSHVDASKDTVKYFFSLD
CCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCEEEEEEECC
>Mature Secondary Structure
MRSIVIAAGGTGGHISPGVALAEVLTDLKEKIGYENLYLYSLIRNQNNPDLEQAPCPVLW
CCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHCCCCEEE
HNLPPLSSNIFLFPFRYTIQILKTFLLFKKLNVDVVIGMGGYSTVSSILYGILFKKKIYL
CCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHEEEE
CEQNTVPGNVSRLFFRFANKAAFSFPPKNSAIPCDYQVLGNPLRKKTLPKMSLKFSEKYD
EECCCCCCHHHHHHHHHHCCCEEECCCCCCCCCCCHHHHCCHHHHHCCCCHHEEECHHCC
TKKKTQFNVLVMGGSQGARQINNIVIALMGHEEINIQFRFRVLTGSALYEEVSKKTKKDA
CCCCCEEEEEEEECCCCHHHHCCEEEEEECCCEEEEEEEEEEEECHHHHHHHHHHHHCCH
ELISYSDNMKEHYEWANFVIARAGSGVLSECAAFALPMILIPYPYAKDDHQMANARYLEL
HHHHCCCCHHHHHHHHHEEEEECCCCHHHHHHHHHCCHHEECCCCCCCCCHHCCEEEEEE
NGAAIVIDQKDEDESHLFKVLDQIANNVNLLNDMSISSLQCSHVDASKDTVKYFFSLD
CCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA