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The map label for this gene is trpD

Identifier: 116328776

GI number: 116328776

Start: 2524152

End: 2525162

Strand: Reverse

Name: trpD

Synonym: LBL_2151

Alternate gene names: 116328776

Gene position: 2525162-2524152 (Counterclockwise)

Preceding gene: 116328777

Following gene: 116328775

Centisome position: 69.86

GC content: 45.5

Gene sequence:

>1011_bases
ATGGAACCAAGAGCAATCGTTCTTAAACTGATCGAACATAAACATATCAGTGTCGAAGAGGCCGAATTCTTTATGAATCG
TGTGATGAAGGGAGAGGTTTCCGAAATTCTTCTTTCCTCTTTCGTGACTGCGATGCGTGCCAAAGGGGAATCCGTGGATG
AGGTACTCGGTTGTACCCTTGCCCTTCGTAAGAATGCACTCAAGCCTAAGACCGTATTTCCCTTTGATCTTTTGGATACC
TGTGGGACCGGCGGGGACGGCCAAGGCACGATCAATGTCAGTACTCTTTCCGCTATCACTCTCGCTTCTTTAGGAGTTAA
GGTTGCCAAGCATGGAAACCGTTCCGTATCTTCCCATACGGGTTCGAGTGATATTCTCGCTCGTCTCGGGTATCAGACCG
AAGCGACCCAGGAAGAAGTGGAAGCACATCTCATAAGTCGCGGATTTACGTTCTTATTTGCGCCGATGTGGCATCCGTCC
ATGAAGTATGCGGGTTCGGTTCGTAAAGAACTTGGGTTTAGGACTGTGTTTAACATGATCGGTCCTCTTTCCAATCCGTT
TTCCCCACAATTTCAGATCATCGGAGTTTACCAGCCGGAATTGACGGAACTGTTCATTAAGGTTTTACAATACCTAGGTT
TAAAACGAGCTTTGGTTTGTCATTCTCGGGATGGTCTGGACGAATTTTCCATCTTTCAAACCACAGATTATACTCTCTTG
GAAAATGAGGTTATCAGTCGTCATTCTTTTGATCCTAGGACTCTTGGGTTTTCTTCCTTAAAAAGAGAGGAAGTATACGC
CGATTCCAGTGAACATGCGGAAGTTTTAGCCAGAAGAGTTTTGAATTCCGAGCCGATTGCAGGAACACACGCGGTGGCTT
TAAATGCGGGGGCGGGGCTTTTTGTGATGGGAAAGGTAAAAACAATCGAACAAGGTTATAAAATCGCATGGGAGGCCCTC
CTTTCGGGAAAAACGAGAAAGTATTTCGAAGATTTAATTTCCAAAGAGTAA

Upstream 100 bases:

>100_bases
CTCGTTACTACCGCGATCACCGTGATTTCCGGAATTCGATATCTCATTACCAATAATAAGGTTCTTCGACCTTCCCATAT
CAAAAGGATGTTTCAGAAAA

Downstream 100 bases:

>100_bases
ACGGGAAAAATATTGGTAAGAGTTTGACAAAAAAGACCGAACAGGAAAGTAAATCATGATTTTTAATTTCAGCATATTAC
TACCACTGGCGCAGGCCGCC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MEPRAIVLKLIEHKHISVEEAEFFMNRVMKGEVSEILLSSFVTAMRAKGESVDEVLGCTLALRKNALKPKTVFPFDLLDT
CGTGGDGQGTINVSTLSAITLASLGVKVAKHGNRSVSSHTGSSDILARLGYQTEATQEEVEAHLISRGFTFLFAPMWHPS
MKYAGSVRKELGFRTVFNMIGPLSNPFSPQFQIIGVYQPELTELFIKVLQYLGLKRALVCHSRDGLDEFSIFQTTDYTLL
ENEVISRHSFDPRTLGFSSLKREEVYADSSEHAEVLARRVLNSEPIAGTHAVALNAGAGLFVMGKVKTIEQGYKIAWEAL
LSGKTRKYFEDLISKE

Sequences:

>Translated_336_residues
MEPRAIVLKLIEHKHISVEEAEFFMNRVMKGEVSEILLSSFVTAMRAKGESVDEVLGCTLALRKNALKPKTVFPFDLLDT
CGTGGDGQGTINVSTLSAITLASLGVKVAKHGNRSVSSHTGSSDILARLGYQTEATQEEVEAHLISRGFTFLFAPMWHPS
MKYAGSVRKELGFRTVFNMIGPLSNPFSPQFQIIGVYQPELTELFIKVLQYLGLKRALVCHSRDGLDEFSIFQTTDYTLL
ENEVISRHSFDPRTLGFSSLKREEVYADSSEHAEVLARRVLNSEPIAGTHAVALNAGAGLFVMGKVKTIEQGYKIAWEAL
LSGKTRKYFEDLISKE
>Mature_336_residues
MEPRAIVLKLIEHKHISVEEAEFFMNRVMKGEVSEILLSSFVTAMRAKGESVDEVLGCTLALRKNALKPKTVFPFDLLDT
CGTGGDGQGTINVSTLSAITLASLGVKVAKHGNRSVSSHTGSSDILARLGYQTEATQEEVEAHLISRGFTFLFAPMWHPS
MKYAGSVRKELGFRTVFNMIGPLSNPFSPQFQIIGVYQPELTELFIKVLQYLGLKRALVCHSRDGLDEFSIFQTTDYTLL
ENEVISRHSFDPRTLGFSSLKREEVYADSSEHAEVLARRVLNSEPIAGTHAVALNAGAGLFVMGKVKTIEQGYKIAWEAL
LSGKTRKYFEDLISKE

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=282, Percent_Identity=36.5248226950355, Blast_Score=166, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6320561, Length=218, Percent_Identity=36.697247706422, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_LEPBJ (Q04R23)

Other databases:

- EMBL:   CP000350
- RefSeq:   YP_801405.1
- ProteinModelPortal:   Q04R23
- SMR:   Q04R23
- STRING:   Q04R23
- GeneID:   4412134
- GenomeReviews:   CP000350_GR
- KEGG:   lbj:LBJ_2157
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- PhylomeDB:   Q04R23
- ProtClustDB:   PRK00188
- BioCyc:   LBOR355277:LBJ_2157-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 37182; Mature: 37182

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPRAIVLKLIEHKHISVEEAEFFMNRVMKGEVSEILLSSFVTAMRAKGESVDEVLGCTL
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ALRKNALKPKTVFPFDLLDTCGTGGDGQGTINVSTLSAITLASLGVKVAKHGNRSVSSHT
HHHHCCCCCCCCCCHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCC
GSSDILARLGYQTEATQEEVEAHLISRGFTFLFAPMWHPSMKYAGSVRKELGFRTVFNMI
CCHHHHHHHCCCCHHHHHHHHHHHHHCCCHHEEECCCCCCHHHHHHHHHHHHHHHHHHHH
GPLSNPFSPQFQIIGVYQPELTELFIKVLQYLGLKRALVCHSRDGLDEFSIFQTTDYTLL
CCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCEEECCCCHHH
ENEVISRHSFDPRTLGFSSLKREEVYADSSEHAEVLARRVLNSEPIAGTHAVALNAGAGL
HHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCE
FVMGKVKTIEQGYKIAWEALLSGKTRKYFEDLISKE
EEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
>Mature Secondary Structure
MEPRAIVLKLIEHKHISVEEAEFFMNRVMKGEVSEILLSSFVTAMRAKGESVDEVLGCTL
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ALRKNALKPKTVFPFDLLDTCGTGGDGQGTINVSTLSAITLASLGVKVAKHGNRSVSSHT
HHHHCCCCCCCCCCHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCC
GSSDILARLGYQTEATQEEVEAHLISRGFTFLFAPMWHPSMKYAGSVRKELGFRTVFNMI
CCHHHHHHHCCCCHHHHHHHHHHHHHCCCHHEEECCCCCCHHHHHHHHHHHHHHHHHHHH
GPLSNPFSPQFQIIGVYQPELTELFIKVLQYLGLKRALVCHSRDGLDEFSIFQTTDYTLL
CCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCEEECCCCHHH
ENEVISRHSFDPRTLGFSSLKREEVYADSSEHAEVLARRVLNSEPIAGTHAVALNAGAGL
HHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCE
FVMGKVKTIEQGYKIAWEALLSGKTRKYFEDLISKE
EEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA