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The map label for this gene is cysW [H]

Identifier: 116328766

GI number: 116328766

Start: 2512441

End: 2513280

Strand: Reverse

Name: cysW [H]

Synonym: LBL_2141

Alternate gene names: 116328766

Gene position: 2513280-2512441 (Counterclockwise)

Preceding gene: 116328767

Following gene: 116328765

Centisome position: 69.53

GC content: 43.57

Gene sequence:

>840_bases
ATGAGACAAGAATCTTTACTCGTTCGAAGTATTCTTATCGGAGCGGTCTTTTTACTGACCGGATTGATTTTGATCCTTCC
TATCTATACGGTTTTTCACGAGGCGTTCTCAAAAGGCATTCGGGCCTACTTGGAAGGAATTCAGGAACCCGATACGTTGT
CCGCTCTTAAACTGACTCTTTTGGTGGTTTCGATTGCGGTGCCTTTGAATACGATCTTCGGAATAGTTTCCGCATTTTCA
TTGACCCGTTTCGAATTTCCGGGAAAGAGTTGGCTTCTTACGATCATAGATTCTCCGTTTTCCGTTTCGCCCGTGATCTC
AGGTTTGATCTTCATTCTTCTTTTCGGAAGGCAAGGTTGGTTCGGGCCCTGGTTGGAAAAAATGAACATCAAAATCGTGT
TCAACATTCCGGGGCTTGTTATTGCGACCATTTTTATCACTCTTCCTTTCGTTGCGAGAGAACTCATTCCATTACTCGAT
TCGACGGGAATCGAAGAAGAGGAAGCGGGACTTCTTTTAGGGGCTTCCCCGACCAAAGTATTCTTTAAAATCGTAACGCC
CGGAATCAAATACGGGTTGTTATACGGAATCATTCTTTGCAACGCAAGAGCGATGGGGGAATTTGGGGCTGTCTCCGTTC
TTTCCGGTCATATCCGAGGGCAAACGAATACGTTACCTTTGCAGATTGAAGTTCTTTATAACGAATACAATTCGATGGCC
GCTTTTTCCGCGGCTTCTCTTCTCGTTTTTTTATCTTTAGTCACCCTAGTTGCAAAACAGGTCTTGGAAAGTAAGATCAA
AATCACCAGAAAAAAAGAATTGTTCCAAGAAGAGGTATAG

Upstream 100 bases:

>100_bases
ACGAAGAAGCAACCGGAATAGCGTTTATCATGCTTGTAGTCTCTTTTAGTATATTATTGTGTATTAATATTATTCAGACG
GTTGCCGCAAGGAGAAAGGG

Downstream 100 bases:

>100_bases
TCATGGGCATCGAAGTTAAGAATCTTGTGAAACGATTCCGAAATTTTACCGCCATCGATCGTCTTTCTTTGGAAGTTCCC
GCGGGAGAGTTGGTCGCTTT

Product: ABC transporter permease

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MRQESLLVRSILIGAVFLLTGLILILPIYTVFHEAFSKGIRAYLEGIQEPDTLSALKLTLLVVSIAVPLNTIFGIVSAFS
LTRFEFPGKSWLLTIIDSPFSVSPVISGLIFILLFGRQGWFGPWLEKMNIKIVFNIPGLVIATIFITLPFVARELIPLLD
STGIEEEEAGLLLGASPTKVFFKIVTPGIKYGLLYGIILCNARAMGEFGAVSVLSGHIRGQTNTLPLQIEVLYNEYNSMA
AFSAASLLVFLSLVTLVAKQVLESKIKITRKKELFQEEV

Sequences:

>Translated_279_residues
MRQESLLVRSILIGAVFLLTGLILILPIYTVFHEAFSKGIRAYLEGIQEPDTLSALKLTLLVVSIAVPLNTIFGIVSAFS
LTRFEFPGKSWLLTIIDSPFSVSPVISGLIFILLFGRQGWFGPWLEKMNIKIVFNIPGLVIATIFITLPFVARELIPLLD
STGIEEEEAGLLLGASPTKVFFKIVTPGIKYGLLYGIILCNARAMGEFGAVSVLSGHIRGQTNTLPLQIEVLYNEYNSMA
AFSAASLLVFLSLVTLVAKQVLESKIKITRKKELFQEEV
>Mature_279_residues
MRQESLLVRSILIGAVFLLTGLILILPIYTVFHEAFSKGIRAYLEGIQEPDTLSALKLTLLVVSIAVPLNTIFGIVSAFS
LTRFEFPGKSWLLTIIDSPFSVSPVISGLIFILLFGRQGWFGPWLEKMNIKIVFNIPGLVIATIFITLPFVARELIPLLD
STGIEEEEAGLLLGASPTKVFFKIVTPGIKYGLLYGIILCNARAMGEFGAVSVLSGHIRGQTNTLPLQIEVLYNEYNSMA
AFSAASLLVFLSLVTLVAKQVLESKIKITRKKELFQEEV

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4208

COG function: function code P; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=270, Percent_Identity=47.4074074074074, Blast_Score=271, Evalue=5e-74,
Organism=Escherichia coli, GI1788764, Length=223, Percent_Identity=36.7713004484305, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1786980, Length=228, Percent_Identity=30.2631578947368, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011866
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30693; Mature: 30693

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQESLLVRSILIGAVFLLTGLILILPIYTVFHEAFSKGIRAYLEGIQEPDTLSALKLTL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LVVSIAVPLNTIFGIVSAFSLTRFEFPGKSWLLTIIDSPFSVSPVISGLIFILLFGRQGW
HHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCC
FGPWLEKMNIKIVFNIPGLVIATIFITLPFVARELIPLLDSTGIEEEEAGLLLGASPTKV
CCHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCEEECCCHHHH
FFKIVTPGIKYGLLYGIILCNARAMGEFGAVSVLSGHIRGQTNTLPLQIEVLYNEYNSMA
HHHHHCCCHHHHHHHHHHHHCCHHCCCCCHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHH
AFSAASLLVFLSLVTLVAKQVLESKIKITRKKELFQEEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRQESLLVRSILIGAVFLLTGLILILPIYTVFHEAFSKGIRAYLEGIQEPDTLSALKLTL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LVVSIAVPLNTIFGIVSAFSLTRFEFPGKSWLLTIIDSPFSVSPVISGLIFILLFGRQGW
HHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCC
FGPWLEKMNIKIVFNIPGLVIATIFITLPFVARELIPLLDSTGIEEEEAGLLLGASPTKV
CCHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCEEECCCHHHH
FFKIVTPGIKYGLLYGIILCNARAMGEFGAVSVLSGHIRGQTNTLPLQIEVLYNEYNSMA
HHHHHCCCHHHHHHHHHHHHCCHHCCCCCHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHH
AFSAASLLVFLSLVTLVAKQVLESKIKITRKKELFQEEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]