Click here to switch to the map view.

The map label for this gene is abcA [H]

Identifier: 116328703

GI number: 116328703

Start: 2432611

End: 2433897

Strand: Reverse

Name: abcA [H]

Synonym: LBL_2075

Alternate gene names: 116328703

Gene position: 2433897-2432611 (Counterclockwise)

Preceding gene: 116328704

Following gene: 116328702

Centisome position: 67.34

GC content: 42.58

Gene sequence:

>1287_bases
TTGAGTTTAAAAGTGGAAAATCTAAATAAGGTTTACGCCGGTTACAGCGGGCCTTTTCAAAGAATTTTAAACGTTCTTTC
TCTCGGATTTTTAGGAAACGACGTCAAATTTGACGCGCTTAGAAACGTAAGTTTTCAAGTTTTTCCGGGAGAAATTGTAG
GTTTGATTGGAAGAAACGGCGCCGGAAAATCCACTCTTTTAAAAGTTCTCAGTGGTGTGTCGTCTTACGCTTCCGGAAAA
ATTTTAAGAACGGGATCTCTTCGTTCCATTCTGGAGCTTGGGGTGGGATTTAATCCGGAACTTTCGGGGGAAGAGAACCT
CTATTACAATGGTCTTGTTTGGGGGCTCAGTCCGGGCGAAATCCGATCCTCCATGAACGAAATTTTCAAATTTTCCGGTC
TACAAGAATTTAAGAATATTCCAATGAAACAATATTCTTCCGGAATGGTCATGCGTCTCGGGTTTGCTCTTGCGACTTTT
TCAAGACCCGACATCCTCATTGTAGACGAGGCTCTCGCTGTGGGTGACGCGAGTTTTCAGCAAAAATGTCTTAGGCGTTT
TCGTTCCTTCCAGGAACAGGGAACTATGACTCTGATTGTAAGTCATGATCTTGAACTTTTAAAATCGGTATGTTCCCGTG
TTTTGATTTTGGAAAAAGGCAAATTGGTTTTCGATGGGAATCCCATAGACGGTTTTCGGGAATACATGCAGATCATTGCA
GGTTCGGCGAGCGGGCAGGAAACTGCTTTTCCATTTCCTAAAGATTCTATTGTGGAAAGTCTTTTCGTGGATTTGAATCT
TGTAGGATTATATCCACCGATACAAGATTTGCGACAAGTTCCGGATCGAATCAATCGGAGTCGTGCAGAGGGTTTGCAAT
ACGAAGATCGGGCGAATCCGCAAATTTTTCCAGTGGGTTCCGAAGTGGAAATTTCAGTCCATGTAATATTCAAGAAGAAT
ATTCCGAATCTTACTGTAGGTTTTCATATAGACGACTCTCGGGGAATCCGGGTCTTTGGAACGAACACATATCATCTCGG
GAATTCGTTGAAAAATATTCATGCAGGGGAATCCGTTTCGGCGAACTTCCGACTTCCTTTGAATTTTTCTGCAGGCAAAT
ACACTCTCGGCGTTGCCTTACACGAAGGAGATAGCCATGTTGAGAATAGTTATCTCTGGAAAGACGGAATTCTTTCCTTC
GAGTTGGAACGTTTAGATTTGCCTAAATTTGAAGGGATTGCTTGGCTTCCGGTACAAGGTAGTCTTAAAAAAGACACTTC
TTCCTGA

Upstream 100 bases:

>100_bases
CGGTTTTTCATTGGAAAGAATTTATTCCTTACTTGATTTTATTTCCTTTGATCGGAATTTTGAGTCGTTCTAAATTTCAT
TCCGTCATTTTGGATCATCT

Downstream 100 bases:

>100_bases
TTTATTTTTCTTTCTCAACCTGAAAAGGTCGGAATTCTGGTTCTCAATATGAAAGTTTGTGTGGTTGGAAGCGGATACGT
AGGTCTTGTCGCAGGCGCTT

Product: ATP-binding protein of an ABC transporter complex

Products: ADP; phosphate; putrescine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MSLKVENLNKVYAGYSGPFQRILNVLSLGFLGNDVKFDALRNVSFQVFPGEIVGLIGRNGAGKSTLLKVLSGVSSYASGK
ILRTGSLRSILELGVGFNPELSGEENLYYNGLVWGLSPGEIRSSMNEIFKFSGLQEFKNIPMKQYSSGMVMRLGFALATF
SRPDILIVDEALAVGDASFQQKCLRRFRSFQEQGTMTLIVSHDLELLKSVCSRVLILEKGKLVFDGNPIDGFREYMQIIA
GSASGQETAFPFPKDSIVESLFVDLNLVGLYPPIQDLRQVPDRINRSRAEGLQYEDRANPQIFPVGSEVEISVHVIFKKN
IPNLTVGFHIDDSRGIRVFGTNTYHLGNSLKNIHAGESVSANFRLPLNFSAGKYTLGVALHEGDSHVENSYLWKDGILSF
ELERLDLPKFEGIAWLPVQGSLKKDTSS

Sequences:

>Translated_428_residues
MSLKVENLNKVYAGYSGPFQRILNVLSLGFLGNDVKFDALRNVSFQVFPGEIVGLIGRNGAGKSTLLKVLSGVSSYASGK
ILRTGSLRSILELGVGFNPELSGEENLYYNGLVWGLSPGEIRSSMNEIFKFSGLQEFKNIPMKQYSSGMVMRLGFALATF
SRPDILIVDEALAVGDASFQQKCLRRFRSFQEQGTMTLIVSHDLELLKSVCSRVLILEKGKLVFDGNPIDGFREYMQIIA
GSASGQETAFPFPKDSIVESLFVDLNLVGLYPPIQDLRQVPDRINRSRAEGLQYEDRANPQIFPVGSEVEISVHVIFKKN
IPNLTVGFHIDDSRGIRVFGTNTYHLGNSLKNIHAGESVSANFRLPLNFSAGKYTLGVALHEGDSHVENSYLWKDGILSF
ELERLDLPKFEGIAWLPVQGSLKKDTSS
>Mature_427_residues
SLKVENLNKVYAGYSGPFQRILNVLSLGFLGNDVKFDALRNVSFQVFPGEIVGLIGRNGAGKSTLLKVLSGVSSYASGKI
LRTGSLRSILELGVGFNPELSGEENLYYNGLVWGLSPGEIRSSMNEIFKFSGLQEFKNIPMKQYSSGMVMRLGFALATFS
RPDILIVDEALAVGDASFQQKCLRRFRSFQEQGTMTLIVSHDLELLKSVCSRVLILEKGKLVFDGNPIDGFREYMQIIAG
SASGQETAFPFPKDSIVESLFVDLNLVGLYPPIQDLRQVPDRINRSRAEGLQYEDRANPQIFPVGSEVEISVHVIFKKNI
PNLTVGFHIDDSRGIRVFGTNTYHLGNSLKNIHAGESVSANFRLPLNFSAGKYTLGVALHEGDSHVENSYLWKDGILSFE
LERLDLPKFEGIAWLPVQGSLKKDTSS

Specific function: Influences the expression of the surface array protein gene (vapA). May have both regulatory and transport activities [H]

COG id: COG1134

COG function: function code GM; ABC-type polysaccharide/polyol phosphate transport system, ATPase component

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI6005701, Length=192, Percent_Identity=31.25, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI27881501, Length=199, Percent_Identity=29.6482412060301, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI30795238, Length=199, Percent_Identity=29.6482412060301, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI153792144, Length=200, Percent_Identity=30.5, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI27477115, Length=192, Percent_Identity=29.6875, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI27436953, Length=192, Percent_Identity=29.6875, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI105990541, Length=229, Percent_Identity=27.9475982532751, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI31657092, Length=205, Percent_Identity=29.7560975609756, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI27262624, Length=207, Percent_Identity=28.9855072463768, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI27262626, Length=207, Percent_Identity=28.9855072463768, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI150417984, Length=237, Percent_Identity=24.4725738396624, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI47078218, Length=231, Percent_Identity=26.4069264069264, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI45446740, Length=231, Percent_Identity=26.4069264069264, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI116734710, Length=202, Percent_Identity=26.2376237623762, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI21536376, Length=195, Percent_Identity=25.1282051282051, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87081791, Length=201, Percent_Identity=29.3532338308458, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87081709, Length=221, Percent_Identity=27.6018099547511, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1787029, Length=204, Percent_Identity=28.4313725490196, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789873, Length=200, Percent_Identity=32, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787547, Length=276, Percent_Identity=27.536231884058, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87081834, Length=208, Percent_Identity=31.25, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1788506, Length=268, Percent_Identity=26.4925373134328, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87081782, Length=208, Percent_Identity=30.7692307692308, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788165, Length=194, Percent_Identity=31.4432989690722, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787370, Length=197, Percent_Identity=23.3502538071066, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788761, Length=214, Percent_Identity=24.7663551401869, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786703, Length=201, Percent_Identity=32.3383084577114, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI48994943, Length=243, Percent_Identity=25.1028806584362, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786398, Length=208, Percent_Identity=25.9615384615385, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789751, Length=223, Percent_Identity=27.8026905829596, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1789032, Length=250, Percent_Identity=22.8, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1786319, Length=196, Percent_Identity=27.0408163265306, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787089, Length=224, Percent_Identity=25.8928571428571, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI48994997, Length=207, Percent_Identity=27.0531400966184, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788210, Length=204, Percent_Identity=27.9411764705882, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788897, Length=206, Percent_Identity=25.2427184466019, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1789593, Length=208, Percent_Identity=26.4423076923077, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI48995001, Length=204, Percent_Identity=28.921568627451, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788225, Length=208, Percent_Identity=24.5192307692308, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790467, Length=202, Percent_Identity=24.2574257425743, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788450, Length=205, Percent_Identity=27.8048780487805, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786563, Length=215, Percent_Identity=24.6511627906977, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1787164, Length=218, Percent_Identity=27.5229357798165, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI87082267, Length=229, Percent_Identity=24.0174672489083, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=198, Percent_Identity=29.2929292929293, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17565586, Length=219, Percent_Identity=27.3972602739726, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71988343, Length=217, Percent_Identity=31.7972350230415, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71983510, Length=201, Percent_Identity=25.3731343283582, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71983523, Length=201, Percent_Identity=25.3731343283582, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71983516, Length=201, Percent_Identity=25.3731343283582, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17510237, Length=201, Percent_Identity=24.3781094527363, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322640, Length=251, Percent_Identity=27.0916334661355, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24666092, Length=216, Percent_Identity=29.6296296296296, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28573571, Length=202, Percent_Identity=27.7227722772277, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28573573, Length=202, Percent_Identity=27.7227722772277, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI116007184, Length=199, Percent_Identity=28.1407035175879, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI221500365, Length=199, Percent_Identity=28.1407035175879, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24643674, Length=199, Percent_Identity=25.6281407035176, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24648314, Length=189, Percent_Identity=27.5132275132275, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI28574150, Length=201, Percent_Identity=24.8756218905473, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI116007328, Length=201, Percent_Identity=24.8756218905473, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24582014, Length=212, Percent_Identity=27.3584905660377, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24582012, Length=212, Percent_Identity=27.3584905660377, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI221512771, Length=192, Percent_Identity=25, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 47316; Mature: 47185

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKVENLNKVYAGYSGPFQRILNVLSLGFLGNDVKFDALRNVSFQVFPGEIVGLIGRNG
CCEECCCCHHHHCCCCCHHHHHHHHHHHHHCCCCCEEHHHHCCEEEEECHHHEEEECCCC
AGKSTLLKVLSGVSSYASGKILRTGSLRSILELGVGFNPELSGEENLYYNGLVWGLSPGE
CCHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCHHH
IRSSMNEIFKFSGLQEFKNIPMKQYSSGMVMRLGFALATFSRPDILIVDEALAVGDASFQ
HHHHHHHHHHHCCHHHHHCCCHHHHCCCCEEHHHHHHHHCCCCCEEEEECHHHCCCHHHH
QKCLRRFRSFQEQGTMTLIVSHDLELLKSVCSRVLILEKGKLVFDGNPIDGFREYMQIIA
HHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHEEEEECCCEEECCCCCHHHHHHHHHHH
GSASGQETAFPFPKDSIVESLFVDLNLVGLYPPIQDLRQVPDRINRSRAEGLQYEDRANP
CCCCCCCCCCCCCHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
QIFPVGSEVEISVHVIFKKNIPNLTVGFHIDDSRGIRVFGTNTYHLGNSLKNIHAGESVS
EEEECCCCEEEEEEEEEECCCCCEEEEEEECCCCCEEEEECCEEECCCCHHHCCCCCCCC
ANFRLPLNFSAGKYTLGVALHEGDSHVENSYLWKDGILSFELERLDLPKFEGIAWLPVQG
CEEEEEEECCCCCEEEEEEEECCCCCCCCCEEECCCCEEEEEHHCCCCCCCCEEEEECCC
SLKKDTSS
CCCCCCCC
>Mature Secondary Structure 
SLKVENLNKVYAGYSGPFQRILNVLSLGFLGNDVKFDALRNVSFQVFPGEIVGLIGRNG
CEECCCCHHHHCCCCCHHHHHHHHHHHHHCCCCCEEHHHHCCEEEEECHHHEEEECCCC
AGKSTLLKVLSGVSSYASGKILRTGSLRSILELGVGFNPELSGEENLYYNGLVWGLSPGE
CCHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCHHH
IRSSMNEIFKFSGLQEFKNIPMKQYSSGMVMRLGFALATFSRPDILIVDEALAVGDASFQ
HHHHHHHHHHHCCHHHHHCCCHHHHCCCCEEHHHHHHHHCCCCCEEEEECHHHCCCHHHH
QKCLRRFRSFQEQGTMTLIVSHDLELLKSVCSRVLILEKGKLVFDGNPIDGFREYMQIIA
HHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHEEEEECCCEEECCCCCHHHHHHHHHHH
GSASGQETAFPFPKDSIVESLFVDLNLVGLYPPIQDLRQVPDRINRSRAEGLQYEDRANP
CCCCCCCCCCCCCHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
QIFPVGSEVEISVHVIFKKNIPNLTVGFHIDDSRGIRVFGTNTYHLGNSLKNIHAGESVS
EEEECCCCEEEEEEEEEECCCCCEEEEEEECCCCCEEEEECCEEECCCCHHHCCCCCCCC
ANFRLPLNFSAGKYTLGVALHEGDSHVENSYLWKDGILSFELERLDLPKFEGIAWLPVQG
CEEEEEEECCCCCEEEEEEEECCCCCCCCCEEECCCCEEEEEHHCCCCCCCCEEEEECCC
SLKKDTSS
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; putrescine [Periplasm]; H2O [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8491726 [H]