| Definition | Leptospira borgpetersenii serovar Hardjo-bovis L550 chromosome 1, complete sequence. |
|---|---|
| Accession | NC_008508 |
| Length | 3,614,446 |
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The map label for this gene is aphA [H]
Identifier: 116328668
GI number: 116328668
Start: 2376561
End: 2379158
Strand: Reverse
Name: aphA [H]
Synonym: LBL_2035
Alternate gene names: 116328668
Gene position: 2379158-2376561 (Counterclockwise)
Preceding gene: 116328671
Following gene: 116328667
Centisome position: 65.82
GC content: 41.15
Gene sequence:
>2598_bases TTGTCGAACGAATGCATTCGTTTTTGGGGATTGAAAGGATTCAATCAGGAGCCGGATACGTTTCCTTCCTTTCTATTTCA TCTTCATGGAAAAATTCGGAACTATGCGGATTTTACCGAAAAGATTCTTTTAAAACACATGCAAGATTTAGAATACTTCG ATACACTTTTTACCGAAAGATACATTTTGCGTTTTTTTTGGAAAGCGGTCTTGAATAAAACGGAGTCGACGTATCGTATT TATACATTCGAAATTTTGGCGCAGGAAGGGGACTGTGGGAATCTTTCTCCGGAAAGTCCTGGAGTGGAATCCATTTTTTA CAAACTTCCGGAACCGGCGTTTTTATTCGATCCGTCCACTTTACGTTTTCTTGCCGTAAACGATGCCGCGATCCATCTCT ATGGGTTTTCCAGAGAGGAATTTGCCGGTATGAATCTTTTGGAAATTCGTCCCGAGGAGGATCGCGCCGATATGGAAACC GCGATCCAAAATGTCGCCAAGGAAACCGGAATTCGTTCCAGAGGAGTTTGGAGACATTGGAGGAAGGACAAAAAATTTCT TTATGTAAAAATCACCACAAACCGAATTTCTCTTGGAGATTCTTTTGCGGTTTTGACGATTTTGACGAATGTTTCCGAGA CGATAGAAACCTCTTATGCCTTAAGGCAAATTCGTGCGGAGAAACAATCCATCATCGAAAGTATGTCGGATCGATATTTT GCGCTTTCCAAAGACTGGAGATTCATTTCTGCGAACCGGCAATCTCTTATTACATTAGGAAAGCCTAAAGAAGAATTGAT AGGAAGGAATATCTGGGATTTGTATCCGGGAGCTTCGGTTCGATCCTTTCGGGACAAATTCGAACTTGCTGTCCGAACTC GAAAGCCGATTACTTTCGAATATAAAATCATAGAAACCGGAAACGTGATGGAGTTTAGGGTTTTTCCTTTTGAGGAAGGG GTCTCCGTGTTTTTTCAGGATATTACGGAAAAAAGGAAAAGAGATTCCGAACAGAACATTCTCAAAGAGATCGCTTTAAA AATTCCGAAAGCGTCGAGCGTGAAAGAATCTTTCGAGATTCTTTTTGAGACGATTTGTAAGGGAACTTTTTGGAATTTTG CCCAAACTTGGAGGTTTCAAAACGGTAAGATCGTTTTGGAGGAGAATTCGCCTTGGTACTCTACGGAAGCGACTTTCTTA CGGTATAGAATCGCTTGTTTTGAAACCGGTTTTTCTCCCGGAGAGGGGTTGATCGGAGAGGTTTTTTCCACTCATAAAAT TCGTTTTGTGAATGACGTTCAAAAGGAAAAAAATTTTAAAAGGACAGGTTTTGTGTTTCAAACCGGAATCCGGTCTTGGA TTGCAATCCCTTTGCGAACCGGACATGAAACTTACGTTCTGGAGTTTTGTTCCCAGATTGAGTTGGATTCAGTAAATTCT TATATTCAAATGTTTGAATTGATTTCGGATCAGATCGAAGTTTTGTTTAAAAACAAGGAATCGGAAGAGGAGAAGGATCA TTTTTTTAAGTTGTCCGGAGACATGTTCCAGATTTCCACGTTGGACGGACAGATCATAGAACGTAACCATGCTTGGGAGG AAGTTTTGGGGTATACTCGGGAGGAATTGAACGGAATCGATCTCGTTAAAATCGTTCATCCGAACGATCGGAACAAGATG TTGAACACCCTCGTGAGTGTTCGAAAATACGGAAAAAATCTTTCGATCGCACTTCGATACGTAACCAAACACGGACGGAC GAGGACGATTCTTTGGAAGACGATCGTTTCCCCGGAACACAGACTTGTTTACACCACGGGTAAGGATATCACCGAAATTC AAAATACCCAGCTCCAACTTGAGAACATGGCGAAAGAACTGCAGCGTTCGAATTCGGATCTGGAAGATTTCGCTTTTATC GCTTCTCACGACCTCCAGGAACCTTTGCGAAAGATTAAGGCGTTCGGAGATCGTCTTTTGAAAAGAAACTCAAATTTGGA TTCGGAATCCGTGGATTATCTGCAAAGAATGTTTTTTTCCGCGCATCGATTATCCAACTTGATCGAAGGTCTTTTGTCTT ATTCTCGGATTAAGAGTAGGGCGAAACCCTTTCAGCTCTTCGATTTAAGAAAAATTTTAAAAGATTCGATCGGCGATTTG GAAATTTATATCAAGGAAAAAAATGCGAGAGTGGTCGATTCTGAAATCGGTTTTGCTTGGTGTGATCCGTTTCAAATGGG GACGGTATTCCAGAATCTGATCAAAAACGGAATTAAATTCAATCAGAGCGAAAACCCCGAAGTGAACATTCGATGTATTC CGCATCCTATCGAACCGAATTGGATTCAAATTACCTTTGCGGATAATGGAATCGGTTTTGACAAAAAGCACGACGGTAAG ATATTTACGCTCTTTCAAAGGTTACACAGCCGGGAAGATTATGAAGGAAACGGAATCGGTCTTGCAGTTTGTAAAAAAAT TATAGAATTTCACGGGGGAAGAATTTACGCCGAAAGCGTTTTACAGAAAGGTTCCACCTTTTATGTGGATCTTCCGGGCG CTCTTACGTCTGTTCAAGAATATGAAAGCCGAAATTAA
Upstream 100 bases:
>100_bases ACCCTTAGACATTCAATTTTTGGAAGAATTCTCTTCGGAGTTTGCTTCCTTTTAAGATCAGATCTGCATACTTGAAGAGT GTTCTTCCGGAAAAATTCTC
Downstream 100 bases:
>100_bases AAATCAAAGTTCGATTCATATACTCGTTGCGGAAGACGATCCGGACGATCGGCTATTGATGAGGGACGGTTTTCGGGAGA ATAATCTGAACAATCCTCTA
Product: sensor histidine kinase of a two component response regulator
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 865; Mature: 864
Protein sequence:
>865_residues MSNECIRFWGLKGFNQEPDTFPSFLFHLHGKIRNYADFTEKILLKHMQDLEYFDTLFTERYILRFFWKAVLNKTESTYRI YTFEILAQEGDCGNLSPESPGVESIFYKLPEPAFLFDPSTLRFLAVNDAAIHLYGFSREEFAGMNLLEIRPEEDRADMET AIQNVAKETGIRSRGVWRHWRKDKKFLYVKITTNRISLGDSFAVLTILTNVSETIETSYALRQIRAEKQSIIESMSDRYF ALSKDWRFISANRQSLITLGKPKEELIGRNIWDLYPGASVRSFRDKFELAVRTRKPITFEYKIIETGNVMEFRVFPFEEG VSVFFQDITEKRKRDSEQNILKEIALKIPKASSVKESFEILFETICKGTFWNFAQTWRFQNGKIVLEENSPWYSTEATFL RYRIACFETGFSPGEGLIGEVFSTHKIRFVNDVQKEKNFKRTGFVFQTGIRSWIAIPLRTGHETYVLEFCSQIELDSVNS YIQMFELISDQIEVLFKNKESEEEKDHFFKLSGDMFQISTLDGQIIERNHAWEEVLGYTREELNGIDLVKIVHPNDRNKM LNTLVSVRKYGKNLSIALRYVTKHGRTRTILWKTIVSPEHRLVYTTGKDITEIQNTQLQLENMAKELQRSNSDLEDFAFI ASHDLQEPLRKIKAFGDRLLKRNSNLDSESVDYLQRMFFSAHRLSNLIEGLLSYSRIKSRAKPFQLFDLRKILKDSIGDL EIYIKEKNARVVDSEIGFAWCDPFQMGTVFQNLIKNGIKFNQSENPEVNIRCIPHPIEPNWIQITFADNGIGFDKKHDGK IFTLFQRLHSREDYEGNGIGLAVCKKIIEFHGGRIYAESVLQKGSTFYVDLPGALTSVQEYESRN
Sequences:
>Translated_865_residues MSNECIRFWGLKGFNQEPDTFPSFLFHLHGKIRNYADFTEKILLKHMQDLEYFDTLFTERYILRFFWKAVLNKTESTYRI YTFEILAQEGDCGNLSPESPGVESIFYKLPEPAFLFDPSTLRFLAVNDAAIHLYGFSREEFAGMNLLEIRPEEDRADMET AIQNVAKETGIRSRGVWRHWRKDKKFLYVKITTNRISLGDSFAVLTILTNVSETIETSYALRQIRAEKQSIIESMSDRYF ALSKDWRFISANRQSLITLGKPKEELIGRNIWDLYPGASVRSFRDKFELAVRTRKPITFEYKIIETGNVMEFRVFPFEEG VSVFFQDITEKRKRDSEQNILKEIALKIPKASSVKESFEILFETICKGTFWNFAQTWRFQNGKIVLEENSPWYSTEATFL RYRIACFETGFSPGEGLIGEVFSTHKIRFVNDVQKEKNFKRTGFVFQTGIRSWIAIPLRTGHETYVLEFCSQIELDSVNS YIQMFELISDQIEVLFKNKESEEEKDHFFKLSGDMFQISTLDGQIIERNHAWEEVLGYTREELNGIDLVKIVHPNDRNKM LNTLVSVRKYGKNLSIALRYVTKHGRTRTILWKTIVSPEHRLVYTTGKDITEIQNTQLQLENMAKELQRSNSDLEDFAFI ASHDLQEPLRKIKAFGDRLLKRNSNLDSESVDYLQRMFFSAHRLSNLIEGLLSYSRIKSRAKPFQLFDLRKILKDSIGDL EIYIKEKNARVVDSEIGFAWCDPFQMGTVFQNLIKNGIKFNQSENPEVNIRCIPHPIEPNWIQITFADNGIGFDKKHDGK IFTLFQRLHSREDYEGNGIGLAVCKKIIEFHGGRIYAESVLQKGSTFYVDLPGALTSVQEYESRN >Mature_864_residues SNECIRFWGLKGFNQEPDTFPSFLFHLHGKIRNYADFTEKILLKHMQDLEYFDTLFTERYILRFFWKAVLNKTESTYRIY TFEILAQEGDCGNLSPESPGVESIFYKLPEPAFLFDPSTLRFLAVNDAAIHLYGFSREEFAGMNLLEIRPEEDRADMETA IQNVAKETGIRSRGVWRHWRKDKKFLYVKITTNRISLGDSFAVLTILTNVSETIETSYALRQIRAEKQSIIESMSDRYFA LSKDWRFISANRQSLITLGKPKEELIGRNIWDLYPGASVRSFRDKFELAVRTRKPITFEYKIIETGNVMEFRVFPFEEGV SVFFQDITEKRKRDSEQNILKEIALKIPKASSVKESFEILFETICKGTFWNFAQTWRFQNGKIVLEENSPWYSTEATFLR YRIACFETGFSPGEGLIGEVFSTHKIRFVNDVQKEKNFKRTGFVFQTGIRSWIAIPLRTGHETYVLEFCSQIELDSVNSY IQMFELISDQIEVLFKNKESEEEKDHFFKLSGDMFQISTLDGQIIERNHAWEEVLGYTREELNGIDLVKIVHPNDRNKML NTLVSVRKYGKNLSIALRYVTKHGRTRTILWKTIVSPEHRLVYTTGKDITEIQNTQLQLENMAKELQRSNSDLEDFAFIA SHDLQEPLRKIKAFGDRLLKRNSNLDSESVDYLQRMFFSAHRLSNLIEGLLSYSRIKSRAKPFQLFDLRKILKDSIGDLE IYIKEKNARVVDSEIGFAWCDPFQMGTVFQNLIKNGIKFNQSENPEVNIRCIPHPIEPNWIQITFADNGIGFDKKHDGKI FTLFQRLHSREDYEGNGIGLAVCKKIIEFHGGRIYAESVLQKGSTFYVDLPGALTSVQEYESRN
Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]
COG id: COG0642
COG function: function code T; Signal transduction histidine kinase
Gene ontology:
Cell location: Integral Membrane Protein. Inner Membrane [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 histidine kinase domain [H]
Homologues:
Organism=Escherichia coli, GI48994928, Length=354, Percent_Identity=25.1412429378531, Blast_Score=77, Evalue=6e-15, Organism=Escherichia coli, GI1789149, Length=251, Percent_Identity=27.8884462151394, Blast_Score=73, Evalue=6e-14, Organism=Escherichia coli, GI145693157, Length=253, Percent_Identity=23.7154150197628, Blast_Score=72, Evalue=1e-13, Organism=Escherichia coli, GI1788713, Length=274, Percent_Identity=24.0875912408759, Blast_Score=63, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003594 - InterPro: IPR003018 - InterPro: IPR013654 - InterPro: IPR016132 - InterPro: IPR001294 - InterPro: IPR013515 - InterPro: IPR003661 - InterPro: IPR005467 - InterPro: IPR009082 [H]
Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]
EC number: =2.7.13.3 [H]
Molecular weight: Translated: 100823; Mature: 100692
Theoretical pI: Translated: 7.29; Mature: 7.29
Prosite motif: PS50112 PAS ; PS50109 HIS_KIN
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 1.4 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 1.3 %Met (Mature Protein) 2.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSNECIRFWGLKGFNQEPDTFPSFLFHLHGKIRNYADFTEKILLKHMQDLEYFDTLFTER CCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH YILRFFWKAVLNKTESTYRIYTFEILAQEGDCGNLSPESPGVESIFYKLPEPAFLFDPST HHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCCCCCCHHHHHHHCCCCCEEECCCC LRFLAVNDAAIHLYGFSREEFAGMNLLEIRPEEDRADMETAIQNVAKETGIRSRGVWRHW EEEEEECCCEEEEEECCHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHH RKDKKFLYVKITTNRISLGDSFAVLTILTNVSETIETSYALRQIRAEKQSIIESMSDRYF CCCCEEEEEEEEECEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE ALSKDWRFISANRQSLITLGKPKEELIGRNIWDLYPGASVRSFRDKFELAVRTRKPITFE EECCCCEEEECCCCEEEECCCCHHHHHCCCHHHCCCCCHHHHHHHHHHHHEECCCCEEEE YKIIETGNVMEFRVFPFEEGVSVFFQDITEKRKRDSEQNILKEIALKIPKASSVKESFEI EEEEECCCEEEEEEECHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHH LFETICKGTFWNFAQTWRFQNGKIVLEENSPWYSTEATFLRYRIACFETGFSPGEGLIGE HHHHHHCCCHHCCHHHEEECCCEEEEECCCCCCCCCHHHHHHEEHHHCCCCCCCCCHHHH VFSTHKIRFVNDVQKEKNFKRTGFVFQTGIRSWIAIPLRTGHETYVLEFCSQIELDSVNS HHCCCCEEEHHHHHHHCCCCCCCHHHHHCCHHEEEEEEECCCHHHHHHHHHHCCHHHHHH YIQMFELISDQIEVLFKNKESEEEKDHFFKLSGDMFQISTLDGQIIERNHAWEEVLGYTR HHHHHHHHHHHHHHHHCCCCCCCHHHHEEEECCCEEEEEECCCHHHHCCCHHHHHHHHHH EELNGIDLVKIVHPNDRNKMLNTLVSVRKYGKNLSIALRYVTKHGRTRTILWKTIVSPEH HHCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCEEEEEEEECCCCCC RLVYTTGKDITEIQNTQLQLENMAKELQRSNSDLEDFAFIASHDLQEPLRKIKAFGDRLL EEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH KRNSNLDSESVDYLQRMFFSAHRLSNLIEGLLSYSRIKSRAKPFQLFDLRKILKDSIGDL HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCE EIYIKEKNARVVDSEIGFAWCDPFQMGTVFQNLIKNGIKFNQSENPEVNIRCIPHPIEPN EEEEEECCCEEEECCCCEEECCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCC WIQITFADNGIGFDKKHDGKIFTLFQRLHSREDYEGNGIGLAVCKKIIEFHGGRIYAESV EEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEHHHH LQKGSTFYVDLPGALTSVQEYESRN HHCCCEEEEECCHHHHHHHHHHCCC >Mature Secondary Structure SNECIRFWGLKGFNQEPDTFPSFLFHLHGKIRNYADFTEKILLKHMQDLEYFDTLFTER CCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH YILRFFWKAVLNKTESTYRIYTFEILAQEGDCGNLSPESPGVESIFYKLPEPAFLFDPST HHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCCCCCCHHHHHHHCCCCCEEECCCC LRFLAVNDAAIHLYGFSREEFAGMNLLEIRPEEDRADMETAIQNVAKETGIRSRGVWRHW EEEEEECCCEEEEEECCHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHH RKDKKFLYVKITTNRISLGDSFAVLTILTNVSETIETSYALRQIRAEKQSIIESMSDRYF CCCCEEEEEEEEECEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE ALSKDWRFISANRQSLITLGKPKEELIGRNIWDLYPGASVRSFRDKFELAVRTRKPITFE EECCCCEEEECCCCEEEECCCCHHHHHCCCHHHCCCCCHHHHHHHHHHHHEECCCCEEEE YKIIETGNVMEFRVFPFEEGVSVFFQDITEKRKRDSEQNILKEIALKIPKASSVKESFEI EEEEECCCEEEEEEECHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHH LFETICKGTFWNFAQTWRFQNGKIVLEENSPWYSTEATFLRYRIACFETGFSPGEGLIGE HHHHHHCCCHHCCHHHEEECCCEEEEECCCCCCCCCHHHHHHEEHHHCCCCCCCCCHHHH VFSTHKIRFVNDVQKEKNFKRTGFVFQTGIRSWIAIPLRTGHETYVLEFCSQIELDSVNS HHCCCCEEEHHHHHHHCCCCCCCHHHHHCCHHEEEEEEECCCHHHHHHHHHHCCHHHHHH YIQMFELISDQIEVLFKNKESEEEKDHFFKLSGDMFQISTLDGQIIERNHAWEEVLGYTR HHHHHHHHHHHHHHHHCCCCCCCHHHHEEEECCCEEEEEECCCHHHHCCCHHHHHHHHHH EELNGIDLVKIVHPNDRNKMLNTLVSVRKYGKNLSIALRYVTKHGRTRTILWKTIVSPEH HHCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCEEEEEEEECCCCCC RLVYTTGKDITEIQNTQLQLENMAKELQRSNSDLEDFAFIASHDLQEPLRKIKAFGDRLL EEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH KRNSNLDSESVDYLQRMFFSAHRLSNLIEGLLSYSRIKSRAKPFQLFDLRKILKDSIGDL HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCE EIYIKEKNARVVDSEIGFAWCDPFQMGTVFQNLIKNGIKFNQSENPEVNIRCIPHPIEPN EEEEEECCCEEEECCCCEEECCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCC WIQITFADNGIGFDKKHDGKIFTLFQRLHSREDYEGNGIGLAVCKKIIEFHGGRIYAESV EEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEHHHH LQKGSTFYVDLPGALTSVQEYESRN HHCCCEEEEECCHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 11759840 [H]