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The map label for this gene is mcpB [H]

Identifier: 116328654

GI number: 116328654

Start: 2359518

End: 2361242

Strand: Reverse

Name: mcpB [H]

Synonym: LBL_2020

Alternate gene names: 116328654

Gene position: 2361242-2359518 (Counterclockwise)

Preceding gene: 116328658

Following gene: 116328653

Centisome position: 65.33

GC content: 42.2

Gene sequence:

>1725_bases
ATGAAAACAATATACATATATATTCAGAGATTGGGAATACGAAAAAAACTGATACTTCTTTTCGGTTCTGTGCTGATACC
GATTACGGTGTTGGTCGTATTGGCTTTAATCAATACGAAAGATAGAATCGAGGATATTGAAACGATCTATGAGGATCGGG
TAATTCCTCTGAAACAATTGAAGAAGATATCGGATCTATATGCGATTTTCATCGTAGACTGTGTTCACAAGGTAAGAAGT
GGAACGTTTACACCGGAAGAAGGAGTCACTAATCTTGATAAGGCGACTTCCGGAATTCAAGAGGAATGGAGCGCATACGT
TGGAACTTATCTTGTTCCCGAAGAGGAAGCCATCATCCGGGAGTTAAATCCTCTTTTTGTGGCTTCGAACGCCGCGGTAG
CCGAGGCCAGGGACCTGATGGTCAACAAAAACTTTCAGGAATTAGAGTCTTTTGCGGATTCCCGTTTGTATCCTAGAATT
GATCCGGTAACGGAAAAGATCGAAAATCTGATACAGTTGCAATTGAAGATCACGGACAGGATATATATCAAAGCGGAAAA
ACAATTCACTTTTAGTTGGATTTTACTCCTTTTCCTTTCCAGTATAACTTTGATTTACATCGTTCTGATTGCGGTGGTCT
ATTCAATTCAATTGGTCAAGGGGCTTACTACTGTAAGCGGTGCGGTCAAAAATGCGGATTTTTCTCATCCGGTGGAAGTT
GAAGAAGACGAAAAGAAAAAAGACGAACTTTATCTTTTACTGATTACTTTTCGTTTGTTCCAGATCAAGCTCAAAGAAAT
GCTCAGCACGATTATGGACTTTTCCGAAAATCTTGTTGCGGCTTCTGAGGAACTTTCTCGTTCTGCGGATCACCTTTCTG
CGAACGCACAATCCGAATCTGCTTCGATTGAGGAAATTTCCGCATCGGTGGAAGAGATTAGTTCCGGAATGGAATACGTA
AACCGGAACGCGGAGTCTCAGTATGTCCTGATTTCTTCATTTAACGGGGAAATGCGGGAACTGGAAGGGATGATTAGCAA
GGTGGGGGATGCCGTAAAGAATTCTTTGGAAAAAATTTCGGATATGTATCTTAAAACCGATTTCGGTAAGAAAACGATGG
GAGATCTTTCCGAAAGTATGGAGAAGATCGAAAGTAGTTCGGTTGAGATGCAGTCCATCACGGCGATCATCAAAGAAATA
TCAGAAAAAGTGAATTTACTTGCGCTCAATGCTGCCATCGAGGCTGCGAGGGCTGGAGAACATGGCAGGGGTTTTGCCGT
GGTGGCGAGTGAGATCACAAGACTTGCGGAACAAACGGATTCTAGTGCGATGACGATCGAGGAACTCATTAAAACGAGCA
ATGCGGAAATTGAAACCGGTAGAAAGATCGTTGAAAACTCCGTGAAAGTTTATGCCGAAGTTTTGGGTGGGCTTGAACAT
TTGAAGGAATCCTCCAATCAAATCGTAGCCATTATGGAACTCCAACAGGAGAAAAAGGAAAAAATTCGTTCCGGAATCGA
TCAAGTCGATACCAAGTCGGAGGACATTCGCAATTCCGTTAAAGAACAAAAGATTGCTATTACGGAAACGGCCAACGCTA
TTTCTAATATTTCCACTACCGTCCAAAGTAGTGCGGCAAATTCCGAGGAAATTGCAGGAAGTGCGATCAGTCTTTTACAG
ATTGCGAAGAATCTTCAAGAGACAATGAACTTTCTAAAAGGCTGA

Upstream 100 bases:

>100_bases
GTTTACTTACTTTGTGAACTTGCATCATTAAAAAATGATTCACTTTTTAAAAAACTTGACTGAGTATATATTAAGGCAAT
GATGAAACGCTTTAAATTCT

Downstream 100 bases:

>100_bases
ACGTTTCTACTTTTAAAGGAAGTTGTAAGTTAATAAAACTCAGTAAACTTTTGGTTCGTTTACTGAGTATTTCTTTTTAA
GCTTTATGCTTGTTTTCTGT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: H3 [H]

Number of amino acids: Translated: 574; Mature: 574

Protein sequence:

>574_residues
MKTIYIYIQRLGIRKKLILLFGSVLIPITVLVVLALINTKDRIEDIETIYEDRVIPLKQLKKISDLYAIFIVDCVHKVRS
GTFTPEEGVTNLDKATSGIQEEWSAYVGTYLVPEEEAIIRELNPLFVASNAAVAEARDLMVNKNFQELESFADSRLYPRI
DPVTEKIENLIQLQLKITDRIYIKAEKQFTFSWILLLFLSSITLIYIVLIAVVYSIQLVKGLTTVSGAVKNADFSHPVEV
EEDEKKKDELYLLLITFRLFQIKLKEMLSTIMDFSENLVAASEELSRSADHLSANAQSESASIEEISASVEEISSGMEYV
NRNAESQYVLISSFNGEMRELEGMISKVGDAVKNSLEKISDMYLKTDFGKKTMGDLSESMEKIESSSVEMQSITAIIKEI
SEKVNLLALNAAIEAARAGEHGRGFAVVASEITRLAEQTDSSAMTIEELIKTSNAEIETGRKIVENSVKVYAEVLGGLEH
LKESSNQIVAIMELQQEKKEKIRSGIDQVDTKSEDIRNSVKEQKIAITETANAISNISTTVQSSAANSEEIAGSAISLLQ
IAKNLQETMNFLKG

Sequences:

>Translated_574_residues
MKTIYIYIQRLGIRKKLILLFGSVLIPITVLVVLALINTKDRIEDIETIYEDRVIPLKQLKKISDLYAIFIVDCVHKVRS
GTFTPEEGVTNLDKATSGIQEEWSAYVGTYLVPEEEAIIRELNPLFVASNAAVAEARDLMVNKNFQELESFADSRLYPRI
DPVTEKIENLIQLQLKITDRIYIKAEKQFTFSWILLLFLSSITLIYIVLIAVVYSIQLVKGLTTVSGAVKNADFSHPVEV
EEDEKKKDELYLLLITFRLFQIKLKEMLSTIMDFSENLVAASEELSRSADHLSANAQSESASIEEISASVEEISSGMEYV
NRNAESQYVLISSFNGEMRELEGMISKVGDAVKNSLEKISDMYLKTDFGKKTMGDLSESMEKIESSSVEMQSITAIIKEI
SEKVNLLALNAAIEAARAGEHGRGFAVVASEITRLAEQTDSSAMTIEELIKTSNAEIETGRKIVENSVKVYAEVLGGLEH
LKESSNQIVAIMELQQEKKEKIRSGIDQVDTKSEDIRNSVKEQKIAITETANAISNISTTVQSSAANSEEIAGSAISLLQ
IAKNLQETMNFLKG
>Mature_574_residues
MKTIYIYIQRLGIRKKLILLFGSVLIPITVLVVLALINTKDRIEDIETIYEDRVIPLKQLKKISDLYAIFIVDCVHKVRS
GTFTPEEGVTNLDKATSGIQEEWSAYVGTYLVPEEEAIIRELNPLFVASNAAVAEARDLMVNKNFQELESFADSRLYPRI
DPVTEKIENLIQLQLKITDRIYIKAEKQFTFSWILLLFLSSITLIYIVLIAVVYSIQLVKGLTTVSGAVKNADFSHPVEV
EEDEKKKDELYLLLITFRLFQIKLKEMLSTIMDFSENLVAASEELSRSADHLSANAQSESASIEEISASVEEISSGMEYV
NRNAESQYVLISSFNGEMRELEGMISKVGDAVKNSLEKISDMYLKTDFGKKTMGDLSESMEKIESSSVEMQSITAIIKEI
SEKVNLLALNAAIEAARAGEHGRGFAVVASEITRLAEQTDSSAMTIEELIKTSNAEIETGRKIVENSVKVYAEVLGGLEH
LKESSNQIVAIMELQQEKKEKIRSGIDQVDTKSEDIRNSVKEQKIAITETANAISNISTTVQSSAANSEEIAGSAISLLQ
IAKNLQETMNFLKG

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=339, Percent_Identity=24.7787610619469, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1788194, Length=259, Percent_Identity=27.7992277992278, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1787690, Length=579, Percent_Identity=23.1433506044905, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1788195, Length=250, Percent_Identity=26.8, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1789453, Length=307, Percent_Identity=25.0814332247557, Blast_Score=89, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 63914; Mature: 63914

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIYIYIQRLGIRKKLILLFGSVLIPITVLVVLALINTKDRIEDIETIYEDRVIPLKQL
CCEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHH
KKISDLYAIFIVDCVHKVRSGTFTPEEGVTNLDKATSGIQEEWSAYVGTYLVPEEEAIIR
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCHHHHHHHHHCCCCCCCHHHHHH
ELNPLFVASNAAVAEARDLMVNKNFQELESFADSRLYPRIDPVTEKIENLIQLQLKITDR
HCCCCEEECCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEEECE
IYIKAEKQFTFSWILLLFLSSITLIYIVLIAVVYSIQLVKGLTTVSGAVKNADFSHPVEV
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
EEDEKKKDELYLLLITFRLFQIKLKEMLSTIMDFSENLVAASEELSRSADHLSANAQSES
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
ASIEEISASVEEISSGMEYVNRNAESQYVLISSFNGEMRELEGMISKVGDAVKNSLEKIS
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
DMYLKTDFGKKTMGDLSESMEKIESSSVEMQSITAIIKEISEKVNLLALNAAIEAARAGE
HHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
HGRGFAVVASEITRLAEQTDSSAMTIEELIKTSNAEIETGRKIVENSVKVYAEVLGGLEH
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LKESSNQIVAIMELQQEKKEKIRSGIDQVDTKSEDIRNSVKEQKIAITETANAISNISTT
HHCCCCCEEHHHHHHHHHHHHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQSSAANSEEIAGSAISLLQIAKNLQETMNFLKG
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTIYIYIQRLGIRKKLILLFGSVLIPITVLVVLALINTKDRIEDIETIYEDRVIPLKQL
CCEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHH
KKISDLYAIFIVDCVHKVRSGTFTPEEGVTNLDKATSGIQEEWSAYVGTYLVPEEEAIIR
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCHHHHHHHHHCCCCCCCHHHHHH
ELNPLFVASNAAVAEARDLMVNKNFQELESFADSRLYPRIDPVTEKIENLIQLQLKITDR
HCCCCEEECCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEEECE
IYIKAEKQFTFSWILLLFLSSITLIYIVLIAVVYSIQLVKGLTTVSGAVKNADFSHPVEV
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
EEDEKKKDELYLLLITFRLFQIKLKEMLSTIMDFSENLVAASEELSRSADHLSANAQSES
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
ASIEEISASVEEISSGMEYVNRNAESQYVLISSFNGEMRELEGMISKVGDAVKNSLEKIS
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
DMYLKTDFGKKTMGDLSESMEKIESSSVEMQSITAIIKEISEKVNLLALNAAIEAARAGE
HHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
HGRGFAVVASEITRLAEQTDSSAMTIEELIKTSNAEIETGRKIVENSVKVYAEVLGGLEH
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LKESSNQIVAIMELQQEKKEKIRSGIDQVDTKSEDIRNSVKEQKIAITETANAISNISTT
HHCCCCCEEHHHHHHHHHHHHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQSSAANSEEIAGSAISLLQIAKNLQETMNFLKG
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]