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The map label for this gene is ahpC [C]

Identifier: 116328653

GI number: 116328653

Start: 2358361

End: 2358942

Strand: Reverse

Name: ahpC [C]

Synonym: LBL_2019

Alternate gene names: 116328653

Gene position: 2358942-2358361 (Counterclockwise)

Preceding gene: 116328654

Following gene: 116328652

Centisome position: 65.26

GC content: 41.07

Gene sequence:

>582_bases
ATGCCGCAGGTTACATCCCTAGCACCGGATTTTAAAGCAGAAGCTGTTCTTGGAAAAGAGATCAAGGAAATTAAACTTTC
AGACTATAAAGGAAAATGGGTAGTGTTATTCTTTTACCCGCTTGACTTTACTTTCGTTTGTCCGACTGAAATTATCGAAT
ACGATAACAAACTTCCGGAATTCAAAAAACTCGGAGCGGAAATACTGGGAGTTTCTGTGGATTCAGCTTTTACTCATTTA
GCTTGGAAAAATACTCCTAAAAAAGAAGGTGGAATCGGAGACATCAAATACCCTCTGATTGCGGATCTTACTAAGTCCAT
TTCTAGAGATTACAATGTTTTAACGGATGGTGGAGTTGCTTTAAGAGGAACTTTTATCATTGATCCAGCCGGTCTGATTC
GTCAGGCGACTATCAACGATCTTCCTGTGGGACGTAATATTGACGAGGCGATCCGATTGATCAAAGCTTTCCAATTTGTC
GAAAAACACGGCGAAGTTTGCCCGGCAAACTGGGATGAGGGAAAGAAAACGATGAAAGCCGATCCGGAAAAATCTAAGGA
TTACTTCTCGGCGGTAAATTGA

Upstream 100 bases:

>100_bases
AAAAAAATTAGAATCATTCTAAAAAATATTTGCTTCTGAGGGGTTGGGAGATATCATGGGGAGTCTAAGTTTCAAAGTAA
ATTTAAAAAGGAGAAATAAA

Downstream 100 bases:

>100_bases
TTTTTTTCTGTCCGCAGATGCAAGTCTGCGGATGATGACATATCAGCGCCCCTAGGAAGCGAGGTTTCAGTTACTTGAAG
CGATCCGCAGAATGAGATCG

Product: peroxiredoxin

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 193; Mature: 192

Protein sequence:

>193_residues
MPQVTSLAPDFKAEAVLGKEIKEIKLSDYKGKWVVLFFYPLDFTFVCPTEIIEYDNKLPEFKKLGAEILGVSVDSAFTHL
AWKNTPKKEGGIGDIKYPLIADLTKSISRDYNVLTDGGVALRGTFIIDPAGLIRQATINDLPVGRNIDEAIRLIKAFQFV
EKHGEVCPANWDEGKKTMKADPEKSKDYFSAVN

Sequences:

>Translated_193_residues
MPQVTSLAPDFKAEAVLGKEIKEIKLSDYKGKWVVLFFYPLDFTFVCPTEIIEYDNKLPEFKKLGAEILGVSVDSAFTHL
AWKNTPKKEGGIGDIKYPLIADLTKSISRDYNVLTDGGVALRGTFIIDPAGLIRQATINDLPVGRNIDEAIRLIKAFQFV
EKHGEVCPANWDEGKKTMKADPEKSKDYFSAVN
>Mature_192_residues
PQVTSLAPDFKAEAVLGKEIKEIKLSDYKGKWVVLFFYPLDFTFVCPTEIIEYDNKLPEFKKLGAEILGVSVDSAFTHLA
WKNTPKKEGGIGDIKYPLIADLTKSISRDYNVLTDGGVALRGTFIIDPAGLIRQATINDLPVGRNIDEAIRLIKAFQFVE
KHGEVCPANWDEGKKTMKADPEKSKDYFSAVN

Specific function: Reduces peroxides. May play an important role in eliminating peroxides generated during metabolism [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32189392, Length=187, Percent_Identity=64.1711229946524, Blast_Score=259, Evalue=1e-69,
Organism=Homo sapiens, GI5802974, Length=193, Percent_Identity=58.5492227979275, Blast_Score=249, Evalue=9e-67,
Organism=Homo sapiens, GI32483377, Length=190, Percent_Identity=58.421052631579, Blast_Score=244, Evalue=2e-65,
Organism=Homo sapiens, GI4505591, Length=185, Percent_Identity=60, Blast_Score=241, Evalue=3e-64,
Organism=Homo sapiens, GI32455266, Length=185, Percent_Identity=60, Blast_Score=241, Evalue=3e-64,
Organism=Homo sapiens, GI32455264, Length=185, Percent_Identity=60, Blast_Score=241, Evalue=3e-64,
Organism=Homo sapiens, GI5453549, Length=192, Percent_Identity=54.6875, Blast_Score=235, Evalue=2e-62,
Organism=Homo sapiens, GI33188454, Length=83, Percent_Identity=71.0843373493976, Blast_Score=124, Evalue=5e-29,
Organism=Homo sapiens, GI4758638, Length=183, Percent_Identity=27.8688524590164, Blast_Score=83, Evalue=2e-16,
Organism=Escherichia coli, GI1786822, Length=170, Percent_Identity=42.9411764705882, Blast_Score=147, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI193204376, Length=183, Percent_Identity=58.4699453551913, Blast_Score=235, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI32565831, Length=183, Percent_Identity=58.4699453551913, Blast_Score=234, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI17554494, Length=186, Percent_Identity=55.9139784946236, Blast_Score=231, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI25153706, Length=191, Percent_Identity=30.3664921465969, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323613, Length=194, Percent_Identity=55.1546391752577, Blast_Score=216, Evalue=2e-57,
Organism=Saccharomyces cerevisiae, GI6320661, Length=194, Percent_Identity=51.0309278350515, Blast_Score=204, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6319407, Length=179, Percent_Identity=34.0782122905028, Blast_Score=105, Evalue=5e-24,
Organism=Drosophila melanogaster, GI17738015, Length=191, Percent_Identity=61.2565445026178, Blast_Score=254, Evalue=3e-68,
Organism=Drosophila melanogaster, GI24656348, Length=191, Percent_Identity=58.6387434554974, Blast_Score=243, Evalue=4e-65,
Organism=Drosophila melanogaster, GI17864676, Length=191, Percent_Identity=58.6387434554974, Blast_Score=243, Evalue=4e-65,
Organism=Drosophila melanogaster, GI17157991, Length=194, Percent_Identity=56.701030927835, Blast_Score=242, Evalue=1e-64,
Organism=Drosophila melanogaster, GI24641739, Length=194, Percent_Identity=56.701030927835, Blast_Score=242, Evalue=1e-64,
Organism=Drosophila melanogaster, GI21357347, Length=190, Percent_Identity=50, Blast_Score=216, Evalue=1e-56,
Organism=Drosophila melanogaster, GI17975518, Length=181, Percent_Identity=35.3591160220994, Blast_Score=100, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24652436, Length=181, Percent_Identity=35.3591160220994, Blast_Score=100, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24652434, Length=181, Percent_Identity=35.3591160220994, Blast_Score=100, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24581278, Length=187, Percent_Identity=31.0160427807487, Blast_Score=99, Evalue=1e-21,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 21529; Mature: 21398

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQVTSLAPDFKAEAVLGKEIKEIKLSDYKGKWVVLFFYPLDFTFVCPTEIIEYDNKLPE
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEECHHHHHHHCCCCCH
FKKLGAEILGVSVDSAFTHLAWKNTPKKEGGIGDIKYPLIADLTKSISRDYNVLTDGGVA
HHHHHHHHEECCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCEE
LRGTFIIDPAGLIRQATINDLPVGRNIDEAIRLIKAFQFVEKHGEVCPANWDEGKKTMKA
EEEEEEECCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCC
DPEKSKDYFSAVN
CCCCHHHHHHCCC
>Mature Secondary Structure 
PQVTSLAPDFKAEAVLGKEIKEIKLSDYKGKWVVLFFYPLDFTFVCPTEIIEYDNKLPE
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEECHHHHHHHCCCCCH
FKKLGAEILGVSVDSAFTHLAWKNTPKKEGGIGDIKYPLIADLTKSISRDYNVLTDGGVA
HHHHHHHHEECCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCEE
LRGTFIIDPAGLIRQATINDLPVGRNIDEAIRLIKAFQFVEKHGEVCPANWDEGKKTMKA
EEEEEEECCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCC
DPEKSKDYFSAVN
CCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]