Click here to switch to the map view.

The map label for this gene is engA [H]

Identifier: 116328637

GI number: 116328637

Start: 2332301

End: 2333764

Strand: Reverse

Name: engA [H]

Synonym: LBL_2000

Alternate gene names: 116328637

Gene position: 2333764-2332301 (Counterclockwise)

Preceding gene: 116328638

Following gene: 116328636

Centisome position: 64.57

GC content: 44.13

Gene sequence:

>1464_bases
ATGGCTAAAGCCGTAAGAAAATCGAATTCGGAAGAAACCGTTCCGATCAAGGCTCCCCGCAAAGCGCCCGGAGAAAAAAT
TCCCGTCGTGTCCATCGTGGGCAGACAAAACGTAGGAAAGTCCACTTTGTTTAATTCTCTTTTGAAGAAAAAACTCGCTA
TCACGGAGGATTATCCCGGTGTGACGCGTGATGTTCTTTCGGCAAGGGTTTATCAGGAAGAAAAGGATCTTGATTTTTAT
CTCTGTGATACTCCCGGGCTCGACATCGAAAACCCGGATTCTCTTTCCCAATCCATATTGGAAGCCGCTTATAGACAATT
GAATGAATCCGACGTAATCATCTTTTTGTTGGATAAGAATTTGGTAACCGTCGCCGACCATACATTACTCGATTATCTGA
GAAAAAAATACGGACCCGTGGACAAACCGATCATCTATTGCGTCAATAAGGCGGACAAAGAGCTCGACGAATTCGATCTT
GAAGAATTCTACAGAATGGGTCTTCCCGAAGTACTGCCGATTTCGGCGACAGGAAGAAAAAATCTGGGGCTATTACTTGA
GAAAATTAAATTTTTCTTAAGTAGTAAGCCGGGCAAGGTTTGGATCGAAAAAATTTCCGCTTCCAAAAAGAAGGACGCGC
AACCCCTACCTCTTGCGGAAGAGGATTACGAGTTCCGGCTTGCGATTGTAGGAAAGCCGAATTCCGGAAAATCCAGCCTT
TTGAACGCGGTCTGCGGTTATGAAAGGGCGGTCGTGAGTGATGTAGCCGGAACGACCCGGGATTCCGTGGATACTTTATT
GGAATTCGGAAATAGAAAACTTCTACTTACTGACACCGCGGGAATTCGCAAGCACAGCAAGACCGCCGAGGCCTTGGAAT
ATTATTCGTATCAAAGAACTCTAAAGGCGATTGAATCGAGTGATCTCGTTATCCACCTTTTGGACGCAAAAAAAGGATTC
GGAGATTTCGATAAAAAGATCACATCCCTATTACAGGAAAAGGGAAAGCCATTTTTGATCGCGGTCAACAAATGGGATTC
CATCGAGGATAAAACCGACAAAACTTTCCGGGAATACAAAGAAAAACTTTACAGTCGTTTTCCGTTGTTAAACGAAGTGC
CGATCGTCACGATCAGTGCGACCGAAAGATTGAGGGTTCAAAAACTTATCGATCTTTCCTTTGATCTCGCATCTAGATCT
CGTAGAAAGGTCAGCACATCCGAACTTAATAAAAATCTAAAAAACTGGATGAGCCAGGCGGGAAGATCCTTTTCGGCCCA
TCAACCGCCGAAGATGCTCTATTGCACACAGGTTTCCACTTCTCCTTTTCACTTGATCCTGTTCGTGAACCACGTGGAAT
ACTTTAAATCGAACTTGATTTCGTTTTTGAAAAAGAAACTCACGGAAGCTTATGACTTGCAGGGGATTCCGGTTCGATTG
GAATTTCGATCGGATCGAAAATGA

Upstream 100 bases:

>100_bases
CGGGATGACATGCAGAAAAAAGACGCGCAACAGGAAATCGCCCGCGCGTTAAAATCATCCAACCGCTACGAGTAATACGC
GATTTAAAACCAGGAATACA

Downstream 100 bases:

>100_bases
ACTTCGCGATTTTTGCATTCCTTAGTTTTATTTCGGGCTCGATTCCTTTTGGATATTGGATTGCTCTTCGATTTGGGAAG
ATGGATATCCGCAAATTCGG

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 487; Mature: 486

Protein sequence:

>487_residues
MAKAVRKSNSEETVPIKAPRKAPGEKIPVVSIVGRQNVGKSTLFNSLLKKKLAITEDYPGVTRDVLSARVYQEEKDLDFY
LCDTPGLDIENPDSLSQSILEAAYRQLNESDVIIFLLDKNLVTVADHTLLDYLRKKYGPVDKPIIYCVNKADKELDEFDL
EEFYRMGLPEVLPISATGRKNLGLLLEKIKFFLSSKPGKVWIEKISASKKKDAQPLPLAEEDYEFRLAIVGKPNSGKSSL
LNAVCGYERAVVSDVAGTTRDSVDTLLEFGNRKLLLTDTAGIRKHSKTAEALEYYSYQRTLKAIESSDLVIHLLDAKKGF
GDFDKKITSLLQEKGKPFLIAVNKWDSIEDKTDKTFREYKEKLYSRFPLLNEVPIVTISATERLRVQKLIDLSFDLASRS
RRKVSTSELNKNLKNWMSQAGRSFSAHQPPKMLYCTQVSTSPFHLILFVNHVEYFKSNLISFLKKKLTEAYDLQGIPVRL
EFRSDRK

Sequences:

>Translated_487_residues
MAKAVRKSNSEETVPIKAPRKAPGEKIPVVSIVGRQNVGKSTLFNSLLKKKLAITEDYPGVTRDVLSARVYQEEKDLDFY
LCDTPGLDIENPDSLSQSILEAAYRQLNESDVIIFLLDKNLVTVADHTLLDYLRKKYGPVDKPIIYCVNKADKELDEFDL
EEFYRMGLPEVLPISATGRKNLGLLLEKIKFFLSSKPGKVWIEKISASKKKDAQPLPLAEEDYEFRLAIVGKPNSGKSSL
LNAVCGYERAVVSDVAGTTRDSVDTLLEFGNRKLLLTDTAGIRKHSKTAEALEYYSYQRTLKAIESSDLVIHLLDAKKGF
GDFDKKITSLLQEKGKPFLIAVNKWDSIEDKTDKTFREYKEKLYSRFPLLNEVPIVTISATERLRVQKLIDLSFDLASRS
RRKVSTSELNKNLKNWMSQAGRSFSAHQPPKMLYCTQVSTSPFHLILFVNHVEYFKSNLISFLKKKLTEAYDLQGIPVRL
EFRSDRK
>Mature_486_residues
AKAVRKSNSEETVPIKAPRKAPGEKIPVVSIVGRQNVGKSTLFNSLLKKKLAITEDYPGVTRDVLSARVYQEEKDLDFYL
CDTPGLDIENPDSLSQSILEAAYRQLNESDVIIFLLDKNLVTVADHTLLDYLRKKYGPVDKPIIYCVNKADKELDEFDLE
EFYRMGLPEVLPISATGRKNLGLLLEKIKFFLSSKPGKVWIEKISASKKKDAQPLPLAEEDYEFRLAIVGKPNSGKSSLL
NAVCGYERAVVSDVAGTTRDSVDTLLEFGNRKLLLTDTAGIRKHSKTAEALEYYSYQRTLKAIESSDLVIHLLDAKKGFG
DFDKKITSLLQEKGKPFLIAVNKWDSIEDKTDKTFREYKEKLYSRFPLLNEVPIVTISATERLRVQKLIDLSFDLASRSR
RKVSTSELNKNLKNWMSQAGRSFSAHQPPKMLYCTQVSTSPFHLILFVNHVEYFKSNLISFLKKKLTEAYDLQGIPVRLE
FRSDRK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=486, Percent_Identity=31.2757201646091, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI2367268, Length=92, Percent_Identity=40.2173913043478, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788919, Length=152, Percent_Identity=33.5526315789474, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17507259, Length=123, Percent_Identity=34.9593495934959, Blast_Score=75, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6323665, Length=151, Percent_Identity=33.112582781457, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI45550813, Length=92, Percent_Identity=42.3913043478261, Blast_Score=80, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 55278; Mature: 55147

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKAVRKSNSEETVPIKAPRKAPGEKIPVVSIVGRQNVGKSTLFNSLLKKKLAITEDYPG
CCCCHHCCCCCCCCEECCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCC
VTRDVLSARVYQEEKDLDFYLCDTPGLDIENPDSLSQSILEAAYRQLNESDVIIFLLDKN
HHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCC
LVTVADHTLLDYLRKKYGPVDKPIIYCVNKADKELDEFDLEEFYRMGLPEVLPISATGRK
EEEHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHCCHHHHHHCCCCCEEEECCCCCC
NLGLLLEKIKFFLSSKPGKVWIEKISASKKKDAQPLPLAEEDYEFRLAIVGKPNSGKSSL
HHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHH
LNAVCGYERAVVSDVAGTTRDSVDTLLEFGNRKLLLTDTAGIRKHSKTAEALEYYSYQRT
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHH
LKAIESSDLVIHLLDAKKGFGDFDKKITSLLQEKGKPFLIAVNKWDSIEDKTDKTFREYK
HHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHH
EKLYSRFPLLNEVPIVTISATERLRVQKLIDLSFDLASRSRRKVSTSELNKNLKNWMSQA
HHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
GRSFSAHQPPKMLYCTQVSTSPFHLILFVNHVEYFKSNLISFLKKKLTEAYDLQGIPVRL
CCCCCCCCCCCEEEEEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
EFRSDRK
EECCCCC
>Mature Secondary Structure 
AKAVRKSNSEETVPIKAPRKAPGEKIPVVSIVGRQNVGKSTLFNSLLKKKLAITEDYPG
CCCHHCCCCCCCCEECCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCC
VTRDVLSARVYQEEKDLDFYLCDTPGLDIENPDSLSQSILEAAYRQLNESDVIIFLLDKN
HHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCC
LVTVADHTLLDYLRKKYGPVDKPIIYCVNKADKELDEFDLEEFYRMGLPEVLPISATGRK
EEEHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHCCHHHHHHCCCCCEEEECCCCCC
NLGLLLEKIKFFLSSKPGKVWIEKISASKKKDAQPLPLAEEDYEFRLAIVGKPNSGKSSL
HHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHH
LNAVCGYERAVVSDVAGTTRDSVDTLLEFGNRKLLLTDTAGIRKHSKTAEALEYYSYQRT
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHH
LKAIESSDLVIHLLDAKKGFGDFDKKITSLLQEKGKPFLIAVNKWDSIEDKTDKTFREYK
HHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHH
EKLYSRFPLLNEVPIVTISATERLRVQKLIDLSFDLASRSRRKVSTSELNKNLKNWMSQA
HHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
GRSFSAHQPPKMLYCTQVSTSPFHLILFVNHVEYFKSNLISFLKKKLTEAYDLQGIPVRL
CCCCCCCCCCCEEEEEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
EFRSDRK
EECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA