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The map label for this gene is lepB-2 [H]

Identifier: 116328624

GI number: 116328624

Start: 2313291

End: 2314292

Strand: Reverse

Name: lepB-2 [H]

Synonym: LBL_1983

Alternate gene names: 116328624

Gene position: 2314292-2313291 (Counterclockwise)

Preceding gene: 116328630

Following gene: 116328623

Centisome position: 64.03

GC content: 43.31

Gene sequence:

>1002_bases
ATGAACCTGGAATCTGAGGTAAAAACAAAAAATTCGCTTACCGGAGAGGAATCTCCAATTAGCTCCGCATTTTCCTTTAT
TTTGATCGTGATCTTGGTATTTGCCTTCAAATCCTCGGTTTTGGACGCGAATAATATCCCTTCTGGATCGATGATTCCCA
CCTTAAAAATTGGGGATTTTCTGTTTGTGAATAAGATGAGATACTCGATTCGTATGCCTTTTACCGAAGCGGAACTCATT
CGAATCGACGATCCGAAGCGAGGAGATATCGTCACTTTTGCGCCCCCGCTTCGGGCTCTGGGCGTTGGAGATAGTCGAGA
TGGCTTTTTTGCAAAACGTTATGTGAAGCGTGTAGTCGGACTTCCGGGGGATACGATCCGAATCTCTTCTAAATTTCTTT
CCACGAAAAAAGGAAATGTGAACTATTCCGTGATCGAATACAAGGAAAAAGGATCCGACACATTCCAAGGTTACGAACCT
GTGGAAATAGAAGAAGGAAATATTTTAGGGGATTTAGACAATCTCTACGCACCTACGAGATCTTTGTTTCTGGAAAAAAA
ACCTGGTTTCGAACACTACGTTCTGGAAGGTTACGAAGAAGATCGTAAACGTCTCGACGGATACGAATGTAATTTTTCGA
TCGGATGCGAGATCCCCGAAAATCAGTACATGGTTGTCGGAGATAATCGGGATGATTCTCACGATTCCCGTGCTTGGGGA
TTCGTAAAGCGGGAAGACATACTTGGGAAAGCTTTGGTGATCTATTTTTCCATCAACTGGAAGGACAACGTCTGCGAATA
TAAGAACGGGAAGGAACTTTCTGAAAAAGGACCGGAATTTGCAGAGCGTTATCAGGGAGAAGAACTGATAAAAAATTGTC
ATCCTTCGGAAATCGGTCTAATGAGGGAAGAAAGCAGGCTCGGTTGGATCGAACGCACTCTCCGGTATAGAATTTGGAGG
ATGGAAGTTCGTTGGAATAGGATCGGAAAGATTCTTCGTTAA

Upstream 100 bases:

>100_bases
ATTGCTCTTTCACAGTCAAAGTATCGGTGATTTTTGAAAAACCGATAGAATTTTTAACGCAGGATTTGACAGGGGAGAGA
AGATTCTTTTTGCTTTCCTT

Downstream 100 bases:

>100_bases
ACGTCGCTAAACGAAACGGTTCACGTATATGTCCGAAAAGAATTTAGAATCTTCCGATTCTGATAAAGATAAAAACAAGA
ATCAAGAAGTTCGGAACGCT

Product: Signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MNLESEVKTKNSLTGEESPISSAFSFILIVILVFAFKSSVLDANNIPSGSMIPTLKIGDFLFVNKMRYSIRMPFTEAELI
RIDDPKRGDIVTFAPPLRALGVGDSRDGFFAKRYVKRVVGLPGDTIRISSKFLSTKKGNVNYSVIEYKEKGSDTFQGYEP
VEIEEGNILGDLDNLYAPTRSLFLEKKPGFEHYVLEGYEEDRKRLDGYECNFSIGCEIPENQYMVVGDNRDDSHDSRAWG
FVKREDILGKALVIYFSINWKDNVCEYKNGKELSEKGPEFAERYQGEELIKNCHPSEIGLMREESRLGWIERTLRYRIWR
MEVRWNRIGKILR

Sequences:

>Translated_333_residues
MNLESEVKTKNSLTGEESPISSAFSFILIVILVFAFKSSVLDANNIPSGSMIPTLKIGDFLFVNKMRYSIRMPFTEAELI
RIDDPKRGDIVTFAPPLRALGVGDSRDGFFAKRYVKRVVGLPGDTIRISSKFLSTKKGNVNYSVIEYKEKGSDTFQGYEP
VEIEEGNILGDLDNLYAPTRSLFLEKKPGFEHYVLEGYEEDRKRLDGYECNFSIGCEIPENQYMVVGDNRDDSHDSRAWG
FVKREDILGKALVIYFSINWKDNVCEYKNGKELSEKGPEFAERYQGEELIKNCHPSEIGLMREESRLGWIERTLRYRIWR
MEVRWNRIGKILR
>Mature_333_residues
MNLESEVKTKNSLTGEESPISSAFSFILIVILVFAFKSSVLDANNIPSGSMIPTLKIGDFLFVNKMRYSIRMPFTEAELI
RIDDPKRGDIVTFAPPLRALGVGDSRDGFFAKRYVKRVVGLPGDTIRISSKFLSTKKGNVNYSVIEYKEKGSDTFQGYEP
VEIEEGNILGDLDNLYAPTRSLFLEKKPGFEHYVLEGYEEDRKRLDGYECNFSIGCEIPENQYMVVGDNRDDSHDSRAWG
FVKREDILGKALVIYFSINWKDNVCEYKNGKELSEKGPEFAERYQGEELIKNCHPSEIGLMREESRLGWIERTLRYRIWR
MEVRWNRIGKILR

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=289, Percent_Identity=32.1799307958478, Blast_Score=107, Evalue=7e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 38341; Mature: 38341

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLESEVKTKNSLTGEESPISSAFSFILIVILVFAFKSSVLDANNIPSGSMIPTLKIGDF
CCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCE
LFVNKMRYSIRMPFTEAELIRIDDPKRGDIVTFAPPLRALGVGDSRDGFFAKRYVKRVVG
EEEEEEEEEEECCCCCCEEEEECCCCCCCEEEECCCHHHCCCCCCCCCHHHHHHHHHHHC
LPGDTIRISSKFLSTKKGNVNYSVIEYKEKGSDTFQGYEPVEIEEGNILGDLDNLYAPTR
CCCCEEEEEHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCEEEECCCEEECHHHHHCCHH
SLFLEKKPGFEHYVLEGYEEDRKRLDGYECNFSIGCEIPENQYMVVGDNRDDSHDSRAWG
HHEEECCCCCCHHHHCCCHHHHHHCCCEECCEEEECCCCCCCEEEEECCCCCCCCCHHHC
FVKREDILGKALVIYFSINWKDNVCEYKNGKELSEKGPEFAERYQGEELIKNCHPSEIGL
CEEHHHHCCEEEEEEEEECCCCCCCCCCCCCCHHHCCHHHHHHCCCHHHHHCCCCCHHCC
MREESRLGWIERTLRYRIWRMEVRWNRIGKILR
CHHHHHHHHHHHHHHHEEEEEEEEHHHHHHHCC
>Mature Secondary Structure
MNLESEVKTKNSLTGEESPISSAFSFILIVILVFAFKSSVLDANNIPSGSMIPTLKIGDF
CCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCE
LFVNKMRYSIRMPFTEAELIRIDDPKRGDIVTFAPPLRALGVGDSRDGFFAKRYVKRVVG
EEEEEEEEEEECCCCCCEEEEECCCCCCCEEEECCCHHHCCCCCCCCCHHHHHHHHHHHC
LPGDTIRISSKFLSTKKGNVNYSVIEYKEKGSDTFQGYEPVEIEEGNILGDLDNLYAPTR
CCCCEEEEEHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCEEEECCCEEECHHHHHCCHH
SLFLEKKPGFEHYVLEGYEEDRKRLDGYECNFSIGCEIPENQYMVVGDNRDDSHDSRAWG
HHEEECCCCCCHHHHCCCHHHHHHCCCEECCEEEECCCCCCCEEEEECCCCCCCCCHHHC
FVKREDILGKALVIYFSINWKDNVCEYKNGKELSEKGPEFAERYQGEELIKNCHPSEIGL
CEEHHHHCCEEEEEEEEECCCCCCCCCCCCCCHHHCCHHHHHHCCCHHHHHCCCCCHHCC
MREESRLGWIERTLRYRIWRMEVRWNRIGKILR
CHHHHHHHHHHHHHHHEEEEEEEEHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]