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The map label for this gene is atpA

Identifier: 116328615

GI number: 116328615

Start: 2306422

End: 2307933

Strand: Reverse

Name: atpA

Synonym: LBL_1973

Alternate gene names: 116328615

Gene position: 2307933-2306422 (Counterclockwise)

Preceding gene: 116328616

Following gene: 116328614

Centisome position: 63.85

GC content: 49.47

Gene sequence:

>1512_bases
ATGAAAATTAAGACAGACGAAATTACGTCCGTTCTCAAACAAGAAATTTTAAATTATAAAAAAGACCTCGGTGTTGATGA
AGTCGGAACGGTTTTAGAAATCGGAGACGGAATCGCCAGAGTGTACGGACTGAAGAATGTGATGTCCGGAGAAATGGTCG
AGTTCCAAAACGGAATTTTCGGTCAGGCGTTCAACCTCGAAGACAACTCCGTGGGTGTGGTCGTTTACGGAGATTATCTC
GCCATCCAAGAAGGATTCACCGTTAAAAGAACGAGCCGAATTCTAGAAGTTCCGGTAGGTCCGGAACTTCTAGGCCGCGT
GGTAAATCCGTTAGGCGAGCCTCTCGATGGAAAAGGTCCGATCAACGCGAAACTTACCAGGCCCGTGGAATCTCCCGCTC
CTGGAATTGCGATGAGACAACCGGTCGGCGAGCCGATGCAAACCGGTATCAAAGCGATCGACGCGATGATCCCGATCGGA
CGCGGACAAAGAGAACTGATCATCGGCGACCGTGGAACCGGAAAAACTTCCATCGCACTCGATACCATCATCAATCAAAA
GGGCACGGGCGTTATCTGCGTTTACGTGGCGATCGGTCAGAAAGCTTCTACCGTAGCTTCCACAGTGGAAATGCTTAGAA
ACAAAGGCGCACTCGAATATACGATCGTGGTTTCCGCAACCGCCGCCGAACCCGCTCCGCTTCAATACATCGCTCCTTAT
TCGGGATGTAGTATGGCCGAATACTTTATGTATAACGAAAAAAAAGCGACCCTCGTGGTTTACGATGATCTTTCGAAACA
AGCGGTTGCGTATCGTCAGATGTCCCTTCTACTTCGTCGCCCTCCGGGTAGGGAAGCGTATCCCGGAGACGTATTCTATC
TTCACTCCAGACTTCTCGAAAGAGCGGCGAAACTCGACGACAAATACGGCGCGGGTTCTTTGACCGCACTTCCGATCATC
GAGACTCAGGAAGGCGAGGTTTCCGCATACATTCCTACGAACGTGATTTCGATCACCGACGGACAGATTTATCTTCAGTC
CAACTTGTTCGCATCCGGGAACCGTCCTGCGGTGGACGTGGGGATTTCGGTTTCTCGGGTCGGTTCTGCCGCGCAGATCA
AAGCGATGAAACAAGTCGCCGGTAAGATGAAACTCGAACTCGCACAGTTCCGTGACTTGGAAGCATTTGCTCAGCTCGGA
ACCGAACTCGATCCAGCAACTCAAGCGCAGCTGGATCGAGGAAACAGAATCGTTCAGATGCTCAAGCAACCCGTTTCTTC
TCCTTTTCCGGTGGAAGAACAAGTTGTGGAAATCTTCGCGGTAACCCGCGGTTTTATGGATAAAATTCCTGTGCCGAAGG
TTCAACAATACGGAAAGTTTCTTTTGACTAGGATCAAGGAACAACATTCCGAAGTTCTGGAAGCGATTCGCAAAGAAAAG
AAAATCTCCGACGAAGAGAAACTCGGTGAAGTTCTAAGCGCCATTGCGGAAGAATTTTTAAGAAAGCACTGA

Upstream 100 bases:

>100_bases
GTACAATTCAACGACTTAAAAATCGAAAAGTCCATCGCTTCCCAGCTCGGGGAAATCAAGAAAGCCATGTTGGAAAAGAA
ATTACCGGTTGGAGCCGTCT

Downstream 100 bases:

>100_bases
GATAGAGGTTCGCTTTGGCAACTCCCAGAGAAATCAAAAAAAGAATCAACTCGGTAAAGAACACGAGAAAGATCACCCGG
ACGATGGAAATGGTCTCAAC

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 503; Mature: 503

Protein sequence:

>503_residues
MKIKTDEITSVLKQEILNYKKDLGVDEVGTVLEIGDGIARVYGLKNVMSGEMVEFQNGIFGQAFNLEDNSVGVVVYGDYL
AIQEGFTVKRTSRILEVPVGPELLGRVVNPLGEPLDGKGPINAKLTRPVESPAPGIAMRQPVGEPMQTGIKAIDAMIPIG
RGQRELIIGDRGTGKTSIALDTIINQKGTGVICVYVAIGQKASTVASTVEMLRNKGALEYTIVVSATAAEPAPLQYIAPY
SGCSMAEYFMYNEKKATLVVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLDDKYGAGSLTALPII
ETQEGEVSAYIPTNVISITDGQIYLQSNLFASGNRPAVDVGISVSRVGSAAQIKAMKQVAGKMKLELAQFRDLEAFAQLG
TELDPATQAQLDRGNRIVQMLKQPVSSPFPVEEQVVEIFAVTRGFMDKIPVPKVQQYGKFLLTRIKEQHSEVLEAIRKEK
KISDEEKLGEVLSAIAEEFLRKH

Sequences:

>Translated_503_residues
MKIKTDEITSVLKQEILNYKKDLGVDEVGTVLEIGDGIARVYGLKNVMSGEMVEFQNGIFGQAFNLEDNSVGVVVYGDYL
AIQEGFTVKRTSRILEVPVGPELLGRVVNPLGEPLDGKGPINAKLTRPVESPAPGIAMRQPVGEPMQTGIKAIDAMIPIG
RGQRELIIGDRGTGKTSIALDTIINQKGTGVICVYVAIGQKASTVASTVEMLRNKGALEYTIVVSATAAEPAPLQYIAPY
SGCSMAEYFMYNEKKATLVVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLDDKYGAGSLTALPII
ETQEGEVSAYIPTNVISITDGQIYLQSNLFASGNRPAVDVGISVSRVGSAAQIKAMKQVAGKMKLELAQFRDLEAFAQLG
TELDPATQAQLDRGNRIVQMLKQPVSSPFPVEEQVVEIFAVTRGFMDKIPVPKVQQYGKFLLTRIKEQHSEVLEAIRKEK
KISDEEKLGEVLSAIAEEFLRKH
>Mature_503_residues
MKIKTDEITSVLKQEILNYKKDLGVDEVGTVLEIGDGIARVYGLKNVMSGEMVEFQNGIFGQAFNLEDNSVGVVVYGDYL
AIQEGFTVKRTSRILEVPVGPELLGRVVNPLGEPLDGKGPINAKLTRPVESPAPGIAMRQPVGEPMQTGIKAIDAMIPIG
RGQRELIIGDRGTGKTSIALDTIINQKGTGVICVYVAIGQKASTVASTVEMLRNKGALEYTIVVSATAAEPAPLQYIAPY
SGCSMAEYFMYNEKKATLVVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLDDKYGAGSLTALPII
ETQEGEVSAYIPTNVISITDGQIYLQSNLFASGNRPAVDVGISVSRVGSAAQIKAMKQVAGKMKLELAQFRDLEAFAQLG
TELDPATQAQLDRGNRIVQMLKQPVSSPFPVEEQVVEIFAVTRGFMDKIPVPKVQQYGKFLLTRIKEQHSEVLEAIRKEK
KISDEEKLGEVLSAIAEEFLRKH

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=508, Percent_Identity=60.8267716535433, Blast_Score=607, Evalue=1e-173,
Organism=Homo sapiens, GI4757810, Length=508, Percent_Identity=60.8267716535433, Blast_Score=607, Evalue=1e-173,
Organism=Homo sapiens, GI19913426, Length=306, Percent_Identity=28.1045751633987, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI19913428, Length=305, Percent_Identity=27.8688524590164, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI32189394, Length=365, Percent_Identity=27.1232876712329, Blast_Score=99, Evalue=9e-21,
Organism=Escherichia coli, GI1790172, Length=496, Percent_Identity=53.0241935483871, Blast_Score=532, Evalue=1e-152,
Organism=Escherichia coli, GI1788251, Length=317, Percent_Identity=28.391167192429, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1790170, Length=349, Percent_Identity=25.7879656160458, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71988063, Length=486, Percent_Identity=60.4938271604938, Blast_Score=583, Evalue=1e-167,
Organism=Caenorhabditis elegans, GI71988080, Length=486, Percent_Identity=60.4938271604938, Blast_Score=582, Evalue=1e-166,
Organism=Caenorhabditis elegans, GI71988074, Length=486, Percent_Identity=56.5843621399177, Blast_Score=532, Evalue=1e-151,
Organism=Caenorhabditis elegans, GI17510931, Length=366, Percent_Identity=28.4153005464481, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17570191, Length=323, Percent_Identity=29.4117647058824, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI25144756, Length=390, Percent_Identity=25.8974358974359, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71988068, Length=72, Percent_Identity=52.7777777777778, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17509265, Length=51, Percent_Identity=58.8235294117647, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=492, Percent_Identity=57.1138211382114, Blast_Score=566, Evalue=1e-162,
Organism=Saccharomyces cerevisiae, GI6322581, Length=407, Percent_Identity=27.027027027027, Blast_Score=116, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6319603, Length=299, Percent_Identity=29.4314381270903, Blast_Score=110, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24658560, Length=506, Percent_Identity=58.300395256917, Blast_Score=578, Evalue=1e-165,
Organism=Drosophila melanogaster, GI281361666, Length=294, Percent_Identity=28.9115646258503, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24646341, Length=294, Percent_Identity=28.9115646258503, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI17136796, Length=294, Percent_Identity=28.9115646258503, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24638766, Length=410, Percent_Identity=25.609756097561, Blast_Score=99, Evalue=9e-21,
Organism=Drosophila melanogaster, GI28574560, Length=412, Percent_Identity=25.2427184466019, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_LEPBJ (Q04S16)

Other databases:

- EMBL:   CP000350
- RefSeq:   YP_801062.1
- ProteinModelPortal:   Q04S16
- STRING:   Q04S16
- GeneID:   4410485
- GenomeReviews:   CP000350_GR
- KEGG:   lbj:LBJ_1754
- eggNOG:   COG0056
- HOGENOM:   HBG565875
- OMA:   EFEDKML
- PhylomeDB:   Q04S16
- ProtClustDB:   PRK09281
- BioCyc:   LBOR355277:LBJ_1754-MONOMER
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 54938; Mature: 54938

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKTDEITSVLKQEILNYKKDLGVDEVGTVLEIGDGIARVYGLKNVMSGEMVEFQNGIF
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHCCCCC
GQAFNLEDNSVGVVVYGDYLAIQEGFTVKRTSRILEVPVGPELLGRVVNPLGEPLDGKGP
CEEECCCCCCEEEEEECCEEEEECCCEEECCCCEEECCCCHHHHHHHHHHCCCCCCCCCC
INAKLTRPVESPAPGIAMRQPVGEPMQTGIKAIDAMIPIGRGQRELIIGDRGTGKTSIAL
CCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEH
DTIINQKGTGVICVYVAIGQKASTVASTVEMLRNKGALEYTIVVSATAAEPAPLQYIAPY
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCEEECCC
SGCSMAEYFMYNEKKATLVVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLE
CCCCHHHHHEECCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RAAKLDDKYGAGSLTALPIIETQEGEVSAYIPTNVISITDGQIYLQSNLFASGNRPAVDV
HHHHCCCCCCCCCEEEEEEEECCCCCEEEEECCCEEEEECCEEEEEECEEECCCCCEEEE
GISVSRVGSAAQIKAMKQVAGKMKLELAQFRDLEAFAQLGTELDPATQAQLDRGNRIVQM
CCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHH
LKQPVSSPFPVEEQVVEIFAVTRGFMDKIPVPKVQQYGKFLLTRIKEQHSEVLEAIRKEK
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KISDEEKLGEVLSAIAEEFLRKH
CCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKIKTDEITSVLKQEILNYKKDLGVDEVGTVLEIGDGIARVYGLKNVMSGEMVEFQNGIF
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHCCCCC
GQAFNLEDNSVGVVVYGDYLAIQEGFTVKRTSRILEVPVGPELLGRVVNPLGEPLDGKGP
CEEECCCCCCEEEEEECCEEEEECCCEEECCCCEEECCCCHHHHHHHHHHCCCCCCCCCC
INAKLTRPVESPAPGIAMRQPVGEPMQTGIKAIDAMIPIGRGQRELIIGDRGTGKTSIAL
CCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEH
DTIINQKGTGVICVYVAIGQKASTVASTVEMLRNKGALEYTIVVSATAAEPAPLQYIAPY
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCEEECCC
SGCSMAEYFMYNEKKATLVVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLE
CCCCHHHHHEECCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RAAKLDDKYGAGSLTALPIIETQEGEVSAYIPTNVISITDGQIYLQSNLFASGNRPAVDV
HHHHCCCCCCCCCEEEEEEEECCCCCEEEEECCCEEEEECCEEEEEECEEECCCCCEEEE
GISVSRVGSAAQIKAMKQVAGKMKLELAQFRDLEAFAQLGTELDPATQAQLDRGNRIVQM
CCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHH
LKQPVSSPFPVEEQVVEIFAVTRGFMDKIPVPKVQQYGKFLLTRIKEQHSEVLEAIRKEK
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KISDEEKLGEVLSAIAEEFLRKH
CCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA