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The map label for this gene is atpD

Identifier: 116328613

GI number: 116328613

Start: 2304118

End: 2305521

Strand: Reverse

Name: atpD

Synonym: LBL_1971

Alternate gene names: 116328613

Gene position: 2305521-2304118 (Counterclockwise)

Preceding gene: 116328614

Following gene: 116328612

Centisome position: 63.79

GC content: 49.5

Gene sequence:

>1404_bases
ATGAATAAAGGTAAAATCAAGCAGATCATCGGATCCGTTTTGGACATCGAGTTCGAAAACGGAGAACTTCCCGAAATTTA
TAACGCACTCGAAATCGAAGCGACCGTTTCCGGAAAGAGAGAAATTCTCATTGCGGAAGTGCAAACTCATATCGGAGGAA
AGGCAATTCGTGCGATCGCCCTTTCTTCCACCGATGGTTTGATCCGCGGTCAAGAAGTGACCAACACCGGAAAGCCGATC
AGCGTTCCCGTGGGAGACGCAACTCTTGGAAGAATCTTCAACGTTCTCGGTAAAACCATCGACGAAGGCCCCGCAATCAC
AGTAAAAGAAACCCGTCCGATTCACAGACCGGCTCCTGCGTTCGACGAACTCACTTCCAAAACGGAAGTTTTCGAAACGG
GAATCAAGGTCATCGACCTTCTCGCTCCTTATATCAAAGGTGGAAAGACCGGACTTTTCGGCGGAGCAGGGGTTGGTAAA
ACGGTTCTCATTCAAGAACTCATCAACAATATCGCAAAACAACACGGTGGATTTTCCGTGTTTGCCGGAGTGGGCGAAAG
AACCCGCGAAGGAAACGACCTCTGGAGAGAGATGAAAGAATCAGGAGTGATCGACAAAACCGTTCTTTGTTACGGTCAGA
TGAACGAACCTCCGGGCGCTCGTCTTCGTGTCGCGTTATCCGCTCTTACAATGGCGGAACACTTTCGTGATTCGATCGGA
ACCGACGTTCTTCTGTTCGTGGATAACATCTTCCGATTTTCCCAAGCGGGTTCCGAAGTTTCCGCGCTTTTGGGAAGAAT
GCCGTCCGCGGTAGGTTACCAGCCGACCCTTTCCACGGAAATGGGCGCGCTTCAAGAAAGAATTACATCTACGAAAAAAG
GATCGATCACTTCCGTTCAGGCGATTTACGTTCCTGCGGACGACTTGACCGACCCGGCGCCTGCGAATGCGTTCGCCCAC
TTGGATGCGACTACGGTTCTTTCCCGTGCGATCTCCGACAAAGGGATTTATCCTGCGGTCGATCCGCTCGATTCCACTTC
CCGCGTGATGAATGCGCAGGTTCTCGGAGAAGAACATTACACCGTAGCACGCGAGGTTCAGAGAATTCTTCAGAGATACA
AAGACCTTCAGGATATCATCGCGATCCTCGGTATGGACGAACTTTCCGAGGATGATAAGGTTCTCGTTGCGAGAGCGAGA
AAGATCGAAAAATTCTTATCTCAGCCTTTCCATGTCGCGGAAGTTTTTACCGGAGCTCCGGGAAAATACGTAAAACTCGC
AGATACGGTTCGTTCCTTTAAAGAAGTGATTTCCGGAAATTACGACCACCTTCCCGAGCAGGCGTTTTATATGGTTGGGT
CTATCGACGACGCGATTGAAAAAGCGAAAGGTTATAAAGGATAA

Upstream 100 bases:

>100_bases
TACAACCGCGTTAGACAGGCAAAAATTACTCAGGAAATTTCCGAGATTGTTGCCGGAGCAGATTCACTGAACTAATCTAT
ATGGTATTGGAGCGACTTGG

Downstream 100 bases:

>100_bases
GTGCATGTTCGCACATAAACTGAACGTATCCGTAATCTCTCCCGAAAAAATTCTTTATAAGGGCGAAGTGGATTCTTTGG
TCGTTCCGGGTAGCGAAGGA

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MNKGKIKQIIGSVLDIEFENGELPEIYNALEIEATVSGKREILIAEVQTHIGGKAIRAIALSSTDGLIRGQEVTNTGKPI
SVPVGDATLGRIFNVLGKTIDEGPAITVKETRPIHRPAPAFDELTSKTEVFETGIKVIDLLAPYIKGGKTGLFGGAGVGK
TVLIQELINNIAKQHGGFSVFAGVGERTREGNDLWREMKESGVIDKTVLCYGQMNEPPGARLRVALSALTMAEHFRDSIG
TDVLLFVDNIFRFSQAGSEVSALLGRMPSAVGYQPTLSTEMGALQERITSTKKGSITSVQAIYVPADDLTDPAPANAFAH
LDATTVLSRAISDKGIYPAVDPLDSTSRVMNAQVLGEEHYTVAREVQRILQRYKDLQDIIAILGMDELSEDDKVLVARAR
KIEKFLSQPFHVAEVFTGAPGKYVKLADTVRSFKEVISGNYDHLPEQAFYMVGSIDDAIEKAKGYKG

Sequences:

>Translated_467_residues
MNKGKIKQIIGSVLDIEFENGELPEIYNALEIEATVSGKREILIAEVQTHIGGKAIRAIALSSTDGLIRGQEVTNTGKPI
SVPVGDATLGRIFNVLGKTIDEGPAITVKETRPIHRPAPAFDELTSKTEVFETGIKVIDLLAPYIKGGKTGLFGGAGVGK
TVLIQELINNIAKQHGGFSVFAGVGERTREGNDLWREMKESGVIDKTVLCYGQMNEPPGARLRVALSALTMAEHFRDSIG
TDVLLFVDNIFRFSQAGSEVSALLGRMPSAVGYQPTLSTEMGALQERITSTKKGSITSVQAIYVPADDLTDPAPANAFAH
LDATTVLSRAISDKGIYPAVDPLDSTSRVMNAQVLGEEHYTVAREVQRILQRYKDLQDIIAILGMDELSEDDKVLVARAR
KIEKFLSQPFHVAEVFTGAPGKYVKLADTVRSFKEVISGNYDHLPEQAFYMVGSIDDAIEKAKGYKG
>Mature_467_residues
MNKGKIKQIIGSVLDIEFENGELPEIYNALEIEATVSGKREILIAEVQTHIGGKAIRAIALSSTDGLIRGQEVTNTGKPI
SVPVGDATLGRIFNVLGKTIDEGPAITVKETRPIHRPAPAFDELTSKTEVFETGIKVIDLLAPYIKGGKTGLFGGAGVGK
TVLIQELINNIAKQHGGFSVFAGVGERTREGNDLWREMKESGVIDKTVLCYGQMNEPPGARLRVALSALTMAEHFRDSIG
TDVLLFVDNIFRFSQAGSEVSALLGRMPSAVGYQPTLSTEMGALQERITSTKKGSITSVQAIYVPADDLTDPAPANAFAH
LDATTVLSRAISDKGIYPAVDPLDSTSRVMNAQVLGEEHYTVAREVQRILQRYKDLQDIIAILGMDELSEDDKVLVARAR
KIEKFLSQPFHVAEVFTGAPGKYVKLADTVRSFKEVISGNYDHLPEQAFYMVGSIDDAIEKAKGYKG

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI32189394, Length=465, Percent_Identity=67.5268817204301, Blast_Score=644, Evalue=0.0,
Organism=Homo sapiens, GI19913424, Length=393, Percent_Identity=26.972010178117, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI19913428, Length=370, Percent_Identity=27.027027027027, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI19913426, Length=395, Percent_Identity=26.5822784810127, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI50345984, Length=383, Percent_Identity=26.3707571801567, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI4757810, Length=383, Percent_Identity=26.3707571801567, Blast_Score=99, Evalue=1e-20,
Organism=Escherichia coli, GI1790170, Length=463, Percent_Identity=67.3866090712743, Blast_Score=635, Evalue=0.0,
Organism=Escherichia coli, GI1788251, Length=383, Percent_Identity=30.8093994778068, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1790172, Length=314, Percent_Identity=26.4331210191083, Blast_Score=103, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI25144756, Length=466, Percent_Identity=66.3090128755365, Blast_Score=624, Evalue=1e-179,
Organism=Caenorhabditis elegans, GI17565854, Length=318, Percent_Identity=28.6163522012579, Blast_Score=131, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI17510931, Length=354, Percent_Identity=28.2485875706215, Blast_Score=128, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17570191, Length=350, Percent_Identity=26.2857142857143, Blast_Score=122, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI71988080, Length=340, Percent_Identity=28.5294117647059, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71988063, Length=340, Percent_Identity=28.5294117647059, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71988074, Length=303, Percent_Identity=27.3927392739274, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6322581, Length=461, Percent_Identity=68.763557483731, Blast_Score=644, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=386, Percent_Identity=27.4611398963731, Blast_Score=119, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6319370, Length=416, Percent_Identity=25.4807692307692, Blast_Score=97, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6320016, Length=253, Percent_Identity=26.0869565217391, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24638766, Length=466, Percent_Identity=67.1673819742489, Blast_Score=632, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574560, Length=467, Percent_Identity=63.8115631691649, Blast_Score=592, Evalue=1e-169,
Organism=Drosophila melanogaster, GI24583992, Length=327, Percent_Identity=27.82874617737, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI20129479, Length=330, Percent_Identity=26.3636363636364, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24583988, Length=413, Percent_Identity=25.6658595641646, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24583986, Length=413, Percent_Identity=25.6658595641646, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24583984, Length=413, Percent_Identity=25.6658595641646, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI281361666, Length=358, Percent_Identity=27.6536312849162, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24646341, Length=358, Percent_Identity=27.6536312849162, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI17136796, Length=358, Percent_Identity=27.6536312849162, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24658560, Length=425, Percent_Identity=27.2941176470588, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24638768, Length=96, Percent_Identity=47.9166666666667, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPB_LEPBJ (Q04S18)

Other databases:

- EMBL:   CP000350
- RefSeq:   YP_801060.1
- ProteinModelPortal:   Q04S18
- SMR:   Q04S18
- STRING:   Q04S18
- GeneID:   4410537
- GenomeReviews:   CP000350_GR
- KEGG:   lbj:LBJ_1752
- eggNOG:   COG0055
- HOGENOM:   HBG565875
- OMA:   LTIAERF
- PhylomeDB:   Q04S18
- ProtClustDB:   PRK09280
- BioCyc:   LBOR355277:LBJ_1752-MONOMER
- HAMAP:   MF_01347
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF8
- SMART:   SM00382
- TIGRFAMs:   TIGR01039

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 50589; Mature: 50589

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKGKIKQIIGSVLDIEFENGELPEIYNALEIEATVSGKREILIAEVQTHIGGKAIRAIA
CCCCHHHHHHHHHHEEEECCCCCHHHHHHEEEEEEECCCCEEEEEHHHHHCCCHHHHEEE
LSSTDGLIRGQEVTNTGKPISVPVGDATLGRIFNVLGKTIDEGPAITVKETRPIHRPAPA
EECCCCCEECCEECCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCC
FDELTSKTEVFETGIKVIDLLAPYIKGGKTGLFGGAGVGKTVLIQELINNIAKQHGGFSV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEE
FAGVGERTREGNDLWREMKESGVIDKTVLCYGQMNEPPGARLRVALSALTMAEHFRDSIG
EECCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHC
TDVLLFVDNIFRFSQAGSEVSALLGRMPSAVGYQPTLSTEMGALQERITSTKKGSITSVQ
CCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEE
AIYVPADDLTDPAPANAFAHLDATTVLSRAISDKGIYPAVDPLDSTSRVMNAQVLGEEHY
EEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHH
TVAREVQRILQRYKDLQDIIAILGMDELSEDDKVLVARARKIEKFLSQPFHVAEVFTGAP
HHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCC
GKYVKLADTVRSFKEVISGNYDHLPEQAFYMVGSIDDAIEKAKGYKG
CCEEHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHCCCCC
>Mature Secondary Structure
MNKGKIKQIIGSVLDIEFENGELPEIYNALEIEATVSGKREILIAEVQTHIGGKAIRAIA
CCCCHHHHHHHHHHEEEECCCCCHHHHHHEEEEEEECCCCEEEEEHHHHHCCCHHHHEEE
LSSTDGLIRGQEVTNTGKPISVPVGDATLGRIFNVLGKTIDEGPAITVKETRPIHRPAPA
EECCCCCEECCEECCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCC
FDELTSKTEVFETGIKVIDLLAPYIKGGKTGLFGGAGVGKTVLIQELINNIAKQHGGFSV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEE
FAGVGERTREGNDLWREMKESGVIDKTVLCYGQMNEPPGARLRVALSALTMAEHFRDSIG
EECCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHC
TDVLLFVDNIFRFSQAGSEVSALLGRMPSAVGYQPTLSTEMGALQERITSTKKGSITSVQ
CCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEE
AIYVPADDLTDPAPANAFAHLDATTVLSRAISDKGIYPAVDPLDSTSRVMNAQVLGEEHY
EEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHH
TVAREVQRILQRYKDLQDIIAILGMDELSEDDKVLVARARKIEKFLSQPFHVAEVFTGAP
HHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCC
GKYVKLADTVRSFKEVISGNYDHLPEQAFYMVGSIDDAIEKAKGYKG
CCEEHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA