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The map label for this gene is 116328482

Identifier: 116328482

GI number: 116328482

Start: 2132445

End: 2134046

Strand: Direct

Name: 116328482

Synonym: LBL_1830

Alternate gene names: NA

Gene position: 2132445-2134046 (Clockwise)

Preceding gene: 116328476

Following gene: 116328483

Centisome position: 59.0

GC content: 45.32

Gene sequence:

>1602_bases
ATGAGTAAAGAACCCCCAAAAGAAAACTGGAAATCCAGAACTGGACTCATCCTCACCGTGGCAAGTGGGGCGATTGGTCT
CGGAAATTTCATCCGATTCCCCGGACAAGCTGTTGCAAACGGCGGTGGGGCCTTCATGGTTCCCTACATCATCAGCTTCA
TTCTGGTCGGAATCCCGGTTTGTATTACGGAATGGATCATGGGAAGAATGGGAGGTCGCACCGGCCACAGCGCTCCCTTT
TTGTTCAAAAGTTTTCTTTCCGGATTTCCTCTCCGAATTGTCGGAGCTATCGGGATCACAATTCCCATTCTCATTTATAT
ATATTACGTTTTTATTGAAGCTTGGTGTCTCGCCTATTCCTTCGAATTCTTAACCGGTCAGATCCGACTGAACCCGAACG
GAAACGCTTACCAATCGCAGATCATCGAAGCCGCAGGAAATTATTATTTGGACATTACCGGAGCGCGCGCAAACGGAGAC
GCGATTTCGGGTAAAATTTTCTACACTACTCTCACTTGTTTTATCCTCAACTTCGCGCTCGTTTACCGAGGAATTTCCAA
AGGAATCGAAACCTTTGCGAAAATCGCGGTCCCTTTTATGCTTGTTTGCTCCGCCGTGATTTTAGTTCGAGTTCTTACGT
TAGACAACATCGAGATTGGTCTCGGTAAGATGTGGAACCCAGATTGGTCGGCTCTTTTGAAATCCGAGGTCTGGATCGCC
GCGGCGGGTCAGATTTTTTTCACTTTGTCCGCCGGTTTCGGAATTGCACTCGTCTTCTCAAGTTATCTCAAACGGGACAA
CGACGTAGTCCTTTCTTCCCTTTCCGCCGCCTCCTTAAACGAATTCGTGGAAGTTGCAATCGGCGGTATGATTACGATCC
CGGTCTCCTTTCTTTTCTTAGGCGCTTCGATCAACGACTTCGGCACGTTCGGTATGGGATTCATCGCACTTCCTTCCGTT
TTTTCTTTGATGCCCGGAGGAGAATGGTTCGGTGCAATTTGGTTCTTCGTTCTCTTTCTTGCGGCAATCACGTCTTCCGT
TACGATGTTACAACCGGGAATCATCTTTTTGGAAGAAGCCTTCGGAATTCGCAGACATACTTCCACATTCATTCTGTTCG
TATTCACCGGATGTCTATGTTTTCCGATTCTTTACTTCAATCAAAACTTTCAAGCCCTCGAACTCGCGGACTTTTGGGTC
GGGACCATTCTGATCTTCATACTTGCAAGTATTCAAATTTTCTTATTCGGTTGGAAAATCGGAGCCAAAAAAGGTATAGA
AGACGGAAACGAAGGTTCTCATTTTGAACTTCCAAGATTTTTTTGGTTCGTGATTCAATACATAACTCCGGTATTTTTAA
TCGTCGTATTTATCGCCTTTCTCATCCAAAATCTTCCCGGTCATTTTGAAAGAATGAGTGTGGACGCCATGATTTCACAG
GCAATCGCTCGGGGAACTTCCGTAGAAGTGGCCCGTACGAAAGCGCTCGTCTCAAAATCCGTTTTTTTCGGAATTCTGAT
CGTCTTCAGTTTGATTGTGCTTCTCGTACACTACGCCCTGAAATATAAAGAAAAAAGAGTAAATTTAAGATGGTATTCTT
AG

Upstream 100 bases:

>100_bases
CGAAAAAGTATCTCACCCATTTTATGTCCCGTTTTTTGTAAAACCATCTACTTTTCCTTTGACAACAAGGGGTTTAACGT
GCGTTTTACAAGAAAACATC

Downstream 100 bases:

>100_bases
CACAAGAAGGTTTGACTTGGCAAGGTGTTTCGATCATGACTATTTCTCTGCTTTTGGTGAGTAGCCTTACCGTATTCTGC
ATTTTTAAACTTTTTAAAAC

Product: Na+-dependent symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 533; Mature: 532

Protein sequence:

>533_residues
MSKEPPKENWKSRTGLILTVASGAIGLGNFIRFPGQAVANGGGAFMVPYIISFILVGIPVCITEWIMGRMGGRTGHSAPF
LFKSFLSGFPLRIVGAIGITIPILIYIYYVFIEAWCLAYSFEFLTGQIRLNPNGNAYQSQIIEAAGNYYLDITGARANGD
AISGKIFYTTLTCFILNFALVYRGISKGIETFAKIAVPFMLVCSAVILVRVLTLDNIEIGLGKMWNPDWSALLKSEVWIA
AAGQIFFTLSAGFGIALVFSSYLKRDNDVVLSSLSAASLNEFVEVAIGGMITIPVSFLFLGASINDFGTFGMGFIALPSV
FSLMPGGEWFGAIWFFVLFLAAITSSVTMLQPGIIFLEEAFGIRRHTSTFILFVFTGCLCFPILYFNQNFQALELADFWV
GTILIFILASIQIFLFGWKIGAKKGIEDGNEGSHFELPRFFWFVIQYITPVFLIVVFIAFLIQNLPGHFERMSVDAMISQ
AIARGTSVEVARTKALVSKSVFFGILIVFSLIVLLVHYALKYKEKRVNLRWYS

Sequences:

>Translated_533_residues
MSKEPPKENWKSRTGLILTVASGAIGLGNFIRFPGQAVANGGGAFMVPYIISFILVGIPVCITEWIMGRMGGRTGHSAPF
LFKSFLSGFPLRIVGAIGITIPILIYIYYVFIEAWCLAYSFEFLTGQIRLNPNGNAYQSQIIEAAGNYYLDITGARANGD
AISGKIFYTTLTCFILNFALVYRGISKGIETFAKIAVPFMLVCSAVILVRVLTLDNIEIGLGKMWNPDWSALLKSEVWIA
AAGQIFFTLSAGFGIALVFSSYLKRDNDVVLSSLSAASLNEFVEVAIGGMITIPVSFLFLGASINDFGTFGMGFIALPSV
FSLMPGGEWFGAIWFFVLFLAAITSSVTMLQPGIIFLEEAFGIRRHTSTFILFVFTGCLCFPILYFNQNFQALELADFWV
GTILIFILASIQIFLFGWKIGAKKGIEDGNEGSHFELPRFFWFVIQYITPVFLIVVFIAFLIQNLPGHFERMSVDAMISQ
AIARGTSVEVARTKALVSKSVFFGILIVFSLIVLLVHYALKYKEKRVNLRWYS
>Mature_532_residues
SKEPPKENWKSRTGLILTVASGAIGLGNFIRFPGQAVANGGGAFMVPYIISFILVGIPVCITEWIMGRMGGRTGHSAPFL
FKSFLSGFPLRIVGAIGITIPILIYIYYVFIEAWCLAYSFEFLTGQIRLNPNGNAYQSQIIEAAGNYYLDITGARANGDA
ISGKIFYTTLTCFILNFALVYRGISKGIETFAKIAVPFMLVCSAVILVRVLTLDNIEIGLGKMWNPDWSALLKSEVWIAA
AGQIFFTLSAGFGIALVFSSYLKRDNDVVLSSLSAASLNEFVEVAIGGMITIPVSFLFLGASINDFGTFGMGFIALPSVF
SLMPGGEWFGAIWFFVLFLAAITSSVTMLQPGIIFLEEAFGIRRHTSTFILFVFTGCLCFPILYFNQNFQALELADFWVG
TILIFILASIQIFLFGWKIGAKKGIEDGNEGSHFELPRFFWFVIQYITPVFLIVVFIAFLIQNLPGHFERMSVDAMISQA
IARGTSVEVARTKALVSKSVFFGILIVFSLIVLLVHYALKYKEKRVNLRWYS

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI289191377, Length=512, Percent_Identity=26.953125, Blast_Score=128, Evalue=2e-29,
Organism=Homo sapiens, GI289191351, Length=512, Percent_Identity=26.953125, Blast_Score=128, Evalue=2e-29,
Organism=Homo sapiens, GI4557046, Length=512, Percent_Identity=26.953125, Blast_Score=128, Evalue=2e-29,
Organism=Homo sapiens, GI4507041, Length=503, Percent_Identity=24.4532803180915, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI92859670, Length=510, Percent_Identity=24.7058823529412, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI4507043, Length=489, Percent_Identity=26.5848670756646, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI21361581, Length=505, Percent_Identity=24.3564356435644, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI194018524, Length=297, Percent_Identity=30.6397306397306, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI134304856, Length=353, Percent_Identity=27.4787535410765, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI197276623, Length=513, Percent_Identity=25.3411306042885, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI54607094, Length=513, Percent_Identity=25.3411306042885, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI188528618, Length=396, Percent_Identity=25.5050505050505, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI7657587, Length=506, Percent_Identity=23.1225296442688, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI58219014, Length=291, Percent_Identity=28.1786941580756, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI51468073, Length=296, Percent_Identity=26.6891891891892, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI171184408, Length=509, Percent_Identity=23.5756385068762, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI171184406, Length=509, Percent_Identity=23.5756385068762, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI171184404, Length=509, Percent_Identity=23.5756385068762, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI6005715, Length=532, Percent_Identity=24.6240601503759, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI11181770, Length=298, Percent_Identity=27.8523489932886, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI67782317, Length=508, Percent_Identity=23.2283464566929, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI67782313, Length=508, Percent_Identity=23.2283464566929, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI33354281, Length=303, Percent_Identity=25.7425742574257, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI67782315, Length=508, Percent_Identity=23.2283464566929, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI5032097, Length=361, Percent_Identity=25.207756232687, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI289191353, Length=431, Percent_Identity=26.2180974477958, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI218563756, Length=359, Percent_Identity=25.6267409470752, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI12408638, Length=293, Percent_Identity=25.5972696245734, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI197276625, Length=126, Percent_Identity=34.9206349206349, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI300360519, Length=372, Percent_Identity=22.3118279569892, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17555248, Length=424, Percent_Identity=26.1792452830189, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI25146584, Length=506, Percent_Identity=22.3320158102767, Blast_Score=105, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI71995588, Length=494, Percent_Identity=24.2914979757085, Blast_Score=105, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI133952791, Length=544, Percent_Identity=23.1617647058824, Blast_Score=102, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17535731, Length=386, Percent_Identity=24.3523316062176, Blast_Score=83, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17554804, Length=469, Percent_Identity=20.8955223880597, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17569475, Length=383, Percent_Identity=22.4543080939948, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17542050, Length=137, Percent_Identity=32.1167883211679, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24762620, Length=486, Percent_Identity=26.9547325102881, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24654186, Length=528, Percent_Identity=25.7575757575758, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI17136952, Length=505, Percent_Identity=24.1584158415842, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI281364394, Length=505, Percent_Identity=24.5544554455446, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI28574704, Length=505, Percent_Identity=24.5544554455446, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI17136950, Length=505, Percent_Identity=24.5544554455446, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI28574702, Length=505, Percent_Identity=24.5544554455446, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24582567, Length=476, Percent_Identity=25.8403361344538, Blast_Score=122, Evalue=7e-28,
Organism=Drosophila melanogaster, GI24639514, Length=514, Percent_Identity=26.2645914396887, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI221329674, Length=514, Percent_Identity=26.2645914396887, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24661428, Length=497, Percent_Identity=23.943661971831, Blast_Score=119, Evalue=7e-27,
Organism=Drosophila melanogaster, GI19921936, Length=504, Percent_Identity=23.4126984126984, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24639516, Length=533, Percent_Identity=25.328330206379, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI45550877, Length=525, Percent_Identity=24.952380952381, Blast_Score=108, Evalue=8e-24,
Organism=Drosophila melanogaster, GI281363702, Length=485, Percent_Identity=25.360824742268, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI45551088, Length=492, Percent_Identity=25, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24652942, Length=492, Percent_Identity=25, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI45551183, Length=425, Percent_Identity=27.2941176470588, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI281365034, Length=508, Percent_Identity=24.8031496062992, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24639853, Length=528, Percent_Identity=25.9469696969697, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI281364136, Length=527, Percent_Identity=24.8576850094877, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24655079, Length=298, Percent_Identity=26.8456375838926, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI19921352, Length=516, Percent_Identity=23.8372093023256, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24584353, Length=516, Percent_Identity=23.8372093023256, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24582569, Length=443, Percent_Identity=24.8306997742664, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI281363700, Length=282, Percent_Identity=28.0141843971631, Blast_Score=89, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 58928; Mature: 58797

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKEPPKENWKSRTGLILTVASGAIGLGNFIRFPGQAVANGGGAFMVPYIISFILVGIPV
CCCCCCCHHHCCCCCEEEEEECCCCCCCHHHHCCCHHHCCCCCEEHHHHHHHHHHHHHHH
CITEWIMGRMGGRTGHSAPFLFKSFLSGFPLRIVGAIGITIPILIYIYYVFIEAWCLAYS
HHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEFLTGQIRLNPNGNAYQSQIIEAAGNYYLDITGARANGDAISGKIFYTTLTCFILNFAL
HHHEEEEEEECCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
VYRGISKGIETFAKIAVPFMLVCSAVILVRVLTLDNIEIGLGKMWNPDWSALLKSEVWIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHHHHEE
AAGQIFFTLSAGFGIALVFSSYLKRDNDVVLSSLSAASLNEFVEVAIGGMITIPVSFLFL
ECCEEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
GASINDFGTFGMGFIALPSVFSLMPGGEWFGAIWFFVLFLAAITSSVTMLQPGIIFLEEA
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHH
FGIRRHTSTFILFVFTGCLCFPILYFNQNFQALELADFWVGTILIFILASIQIFLFGWKI
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEC
GAKKGIEDGNEGSHFELPRFFWFVIQYITPVFLIVVFIAFLIQNLPGHFERMSVDAMISQ
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
AIARGTSVEVARTKALVSKSVFFGILIVFSLIVLLVHYALKYKEKRVNLRWYS
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECC
>Mature Secondary Structure 
SKEPPKENWKSRTGLILTVASGAIGLGNFIRFPGQAVANGGGAFMVPYIISFILVGIPV
CCCCCCHHHCCCCCEEEEEECCCCCCCHHHHCCCHHHCCCCCEEHHHHHHHHHHHHHHH
CITEWIMGRMGGRTGHSAPFLFKSFLSGFPLRIVGAIGITIPILIYIYYVFIEAWCLAYS
HHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEFLTGQIRLNPNGNAYQSQIIEAAGNYYLDITGARANGDAISGKIFYTTLTCFILNFAL
HHHEEEEEEECCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
VYRGISKGIETFAKIAVPFMLVCSAVILVRVLTLDNIEIGLGKMWNPDWSALLKSEVWIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHHHHEE
AAGQIFFTLSAGFGIALVFSSYLKRDNDVVLSSLSAASLNEFVEVAIGGMITIPVSFLFL
ECCEEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
GASINDFGTFGMGFIALPSVFSLMPGGEWFGAIWFFVLFLAAITSSVTMLQPGIIFLEEA
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHH
FGIRRHTSTFILFVFTGCLCFPILYFNQNFQALELADFWVGTILIFILASIQIFLFGWKI
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEC
GAKKGIEDGNEGSHFELPRFFWFVIQYITPVFLIVVFIAFLIQNLPGHFERMSVDAMISQ
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
AIARGTSVEVARTKALVSKSVFFGILIVFSLIVLLVHYALKYKEKRVNLRWYS
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]