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The map label for this gene is tldD [C]

Identifier: 116328246

GI number: 116328246

Start: 1836600

End: 1837985

Strand: Direct

Name: tldD [C]

Synonym: LBL_1573

Alternate gene names: 116328246

Gene position: 1836600-1837985 (Clockwise)

Preceding gene: 116328245

Following gene: 116328247

Centisome position: 50.81

GC content: 44.73

Gene sequence:

>1386_bases
ATGCAGACAAACAAAGCCCAACTCATCTTGGAAGCGGGACTTTCCAGGAAAGCGGATTTCGTAGAAATATTTGAGGAAGA
GACAAGATCTTCTTCCGTAAGTTTAAGAGATCAAAAAATAGAACAAAGTTTTGCGGGAATCGATTACGGAATCGGAATCC
GACTTATTTACGGAACCGACGTTCTCTACGCACATACCAACAACGAAGACTCGGAACATTTGATTTCTCTCATAAATCTT
TTAGCGGATTCCAGAGGAACCGCGAGAGAAAAAGGACAAACGCTCGTACTAAAAGGCAATTTGAAATCCTCTTCGTTTTC
GGCAAACGTAAGAGATCCTCGCAAAGTTTCTCCTCATGAAAAGTTAGAAATTTTATTTCGTGCGGACCAAAACGCCCGGA
GCATTTCTTCGAACATAGTTCAAGTCAGCGTTTCCGCATTTGATTCCGTTTCTAGAATCGGAATTTACAATTCGGAAGGA
TTGTTTCTTGAAGATTTGAGGGTAAGAAGTCGCTTTAACATCAACGTCGCCGCGGAAAAAGAAGGAGAACGATTCGTTGC
TTCCGAAAATCCAGGAGCTAGAAAGGGTTTTGAATTTTTCAACGAACTTCCCGTAGATCAACTTTCCAAAACTGCGGCTG
AAAGAGCTCTTTTGATGTTGTCTGCTGGATATATTCAAGGAAAGAAAATGCCTGTTGTGATGGGGAACGGTTTCGGCGGA
GTCATTTTTCACGAGGCCTGTGGACATCCGTTGGAAACAGAGGCGATCCGTAAAAAATCCTCTCCTTTTATGGATAAACT
CGGGAAAAGAATCGCTCAGTCCTGTTTGACCGCTATCGATGACGGAACGATTCCGGATTCTTGGGGAAGTATCTCTGTGG
ATGACGAAGGATCGCTTCCTCAGAAAACAGTTTTGATAGAGAATGGAATTTTAAAAAGTTATCTCGCCGATCGAATCGGA
GCGGAAGAAGTAGGAGTTCCAAAAACCGGAAGCGCTCGAAGAGAAAGTTATATGTACGCTCCCGTTTCTAGAATGAGAAA
CACATACATCGCTGCGGGAAAAGACTCCTTTGATTCCATGTTGTCCGGAATCGAATACGGACTTTTTGCTAAAAAGATGG
GAGGCGGTTCGGTCAATCCGTCTACGGGAGAATTTAATTTTTCCGTAGAAGAAGGATACGTTATCCGAAATGGTAAGATT
GCGGAGCCGGTCAGAGGCGCGACGCTCATCGGCAAAGGAGACGAAATTCTTCCTAAGATCAGTATGGTAGGCAACGACTT
GGAACTTGCTGCCGGAATGTGCGGTGCGGCTTCTGGCTCGGTTCCGGTCACAGTGGGTCAACCTTCCTTGAAAGTGGACG
AGATTCTCGTGGGAGGTCGTTCATGA

Upstream 100 bases:

>100_bases
AAGCAACCGCACATGCGATCAAATACAGAGAAAAAATCAAAAAACCTTGATCAAAGAAGAATTACGGACTCTGAATTTTT
TAGGAGTCTAAAAGGATAGA

Downstream 100 bases:

>100_bases
ATTTGGATAGTTCCGTTGAATACGTATTAGATATTTGTAAAAAGAAAAGATTGGATCAATACGATCTCGTTGGTTCCGAG
TCCAAAGAGGTGGGAATCGA

Product: Zn-dependent protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MQTNKAQLILEAGLSRKADFVEIFEEETRSSSVSLRDQKIEQSFAGIDYGIGIRLIYGTDVLYAHTNNEDSEHLISLINL
LADSRGTAREKGQTLVLKGNLKSSSFSANVRDPRKVSPHEKLEILFRADQNARSISSNIVQVSVSAFDSVSRIGIYNSEG
LFLEDLRVRSRFNINVAAEKEGERFVASENPGARKGFEFFNELPVDQLSKTAAERALLMLSAGYIQGKKMPVVMGNGFGG
VIFHEACGHPLETEAIRKKSSPFMDKLGKRIAQSCLTAIDDGTIPDSWGSISVDDEGSLPQKTVLIENGILKSYLADRIG
AEEVGVPKTGSARRESYMYAPVSRMRNTYIAAGKDSFDSMLSGIEYGLFAKKMGGGSVNPSTGEFNFSVEEGYVIRNGKI
AEPVRGATLIGKGDEILPKISMVGNDLELAAGMCGAASGSVPVTVGQPSLKVDEILVGGRS

Sequences:

>Translated_461_residues
MQTNKAQLILEAGLSRKADFVEIFEEETRSSSVSLRDQKIEQSFAGIDYGIGIRLIYGTDVLYAHTNNEDSEHLISLINL
LADSRGTAREKGQTLVLKGNLKSSSFSANVRDPRKVSPHEKLEILFRADQNARSISSNIVQVSVSAFDSVSRIGIYNSEG
LFLEDLRVRSRFNINVAAEKEGERFVASENPGARKGFEFFNELPVDQLSKTAAERALLMLSAGYIQGKKMPVVMGNGFGG
VIFHEACGHPLETEAIRKKSSPFMDKLGKRIAQSCLTAIDDGTIPDSWGSISVDDEGSLPQKTVLIENGILKSYLADRIG
AEEVGVPKTGSARRESYMYAPVSRMRNTYIAAGKDSFDSMLSGIEYGLFAKKMGGGSVNPSTGEFNFSVEEGYVIRNGKI
AEPVRGATLIGKGDEILPKISMVGNDLELAAGMCGAASGSVPVTVGQPSLKVDEILVGGRS
>Mature_461_residues
MQTNKAQLILEAGLSRKADFVEIFEEETRSSSVSLRDQKIEQSFAGIDYGIGIRLIYGTDVLYAHTNNEDSEHLISLINL
LADSRGTAREKGQTLVLKGNLKSSSFSANVRDPRKVSPHEKLEILFRADQNARSISSNIVQVSVSAFDSVSRIGIYNSEG
LFLEDLRVRSRFNINVAAEKEGERFVASENPGARKGFEFFNELPVDQLSKTAAERALLMLSAGYIQGKKMPVVMGNGFGG
VIFHEACGHPLETEAIRKKSSPFMDKLGKRIAQSCLTAIDDGTIPDSWGSISVDDEGSLPQKTVLIENGILKSYLADRIG
AEEVGVPKTGSARRESYMYAPVSRMRNTYIAAGKDSFDSMLSGIEYGLFAKKMGGGSVNPSTGEFNFSVEEGYVIRNGKI
AEPVRGATLIGKGDEILPKISMVGNDLELAAGMCGAASGSVPVTVGQPSLKVDEILVGGRS

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=457, Percent_Identity=38.7308533916849, Blast_Score=299, Evalue=2e-82,
Organism=Escherichia coli, GI1790682, Length=427, Percent_Identity=25.2927400468384, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 49825; Mature: 49825

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTNKAQLILEAGLSRKADFVEIFEEETRSSSVSLRDQKIEQSFAGIDYGIGIRLIYGTD
CCCCHHHEEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEEEECE
VLYAHTNNEDSEHLISLINLLADSRGTAREKGQTLVLKGNLKSSSFSANVRDPRKVSPHE
EEEEECCCCCHHHHHHHHHHHHCCCCCHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCHH
KLEILFRADQNARSISSNIVQVSVSAFDSVSRIGIYNSEGLFLEDLRVRSRFNINVAAEK
HEEEEEECCCCHHHHHCCEEEEEHHHHHCHHHCEEECCCCCCHHHHHHHHEEEEEEEECC
EGERFVASENPGARKGFEFFNELPVDQLSKTAAERALLMLSAGYIQGKKMPVVMGNGFGG
CCCEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHEEECCCCCCCCEEEEEECCCCC
VIFHEACGHPLETEAIRKKSSPFMDKLGKRIAQSCLTAIDDGTIPDSWGSISVDDEGSLP
EEEHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCC
QKTVLIENGILKSYLADRIGAEEVGVPKTGSARRESYMYAPVSRMRNTYIAAGKDSFDSM
CEEEEEECCHHHHHHHHHCCCHHCCCCCCCCHHHHCEEECCHHHHCCEEEECCCCHHHHH
LSGIEYGLFAKKMGGGSVNPSTGEFNFSVEEGYVIRNGKIAEPVRGATLIGKGDEILPKI
HHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEEECCCCCCCCCCCEEECCCCHHCCHH
SMVGNDLELAAGMCGAASGSVPVTVGQPSLKVDEILVGGRS
HHCCCCHHHHHCCCCCCCCCEEEEECCCCCEEEHEEECCCC
>Mature Secondary Structure
MQTNKAQLILEAGLSRKADFVEIFEEETRSSSVSLRDQKIEQSFAGIDYGIGIRLIYGTD
CCCCHHHEEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEEEECE
VLYAHTNNEDSEHLISLINLLADSRGTAREKGQTLVLKGNLKSSSFSANVRDPRKVSPHE
EEEEECCCCCHHHHHHHHHHHHCCCCCHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCHH
KLEILFRADQNARSISSNIVQVSVSAFDSVSRIGIYNSEGLFLEDLRVRSRFNINVAAEK
HEEEEEECCCCHHHHHCCEEEEEHHHHHCHHHCEEECCCCCCHHHHHHHHEEEEEEEECC
EGERFVASENPGARKGFEFFNELPVDQLSKTAAERALLMLSAGYIQGKKMPVVMGNGFGG
CCCEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHEEECCCCCCCCEEEEEECCCCC
VIFHEACGHPLETEAIRKKSSPFMDKLGKRIAQSCLTAIDDGTIPDSWGSISVDDEGSLP
EEEHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCC
QKTVLIENGILKSYLADRIGAEEVGVPKTGSARRESYMYAPVSRMRNTYIAAGKDSFDSM
CEEEEEECCHHHHHHHHHCCCHHCCCCCCCCHHHHCEEECCHHHHCCEEEECCCCHHHHH
LSGIEYGLFAKKMGGGSVNPSTGEFNFSVEEGYVIRNGKIAEPVRGATLIGKGDEILPKI
HHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEEECCCCCCCCCCCEEECCCCHHCCHH
SMVGNDLELAAGMCGAASGSVPVTVGQPSLKVDEILVGGRS
HHCCCCHHHHHCCCCCCCCCEEEEECCCCCEEEHEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]