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The map label for this gene is engD [H]

Identifier: 116328196

GI number: 116328196

Start: 1776939

End: 1778036

Strand: Direct

Name: engD [H]

Synonym: LBL_1520

Alternate gene names: 116328196

Gene position: 1776939-1778036 (Clockwise)

Preceding gene: 116328195

Following gene: 116328197

Centisome position: 49.16

GC content: 42.08

Gene sequence:

>1098_bases
ATGAGTCTGAATTGCGGTATTGTCGGCCTTCCCAATGTAGGTAAATCTACTATTTTCAACGCCCTTACAAAAGCGGGTGC
ACAGATGGAAAATTATCCGTTTTGTACCATCGAACCTAACAAAGGAATTGTGGAAGTTCCAGATTTAAGACTGGAGCGAC
TCGCGGAAATCGCAAAACCTCAAAAGGTAGTTCCCGCTATCATAGAATTCGTGGACATCGCCGGTCTTGTCAAAGGCGCT
AGCCAAGGAGAAGGTCTTGGTAATAAATTTCTTTCCCATATCCGAGAAGTGGATACGATTTGTCACGTTGTGCGTGCCTT
TGAAGATGAAAACGTTACCCACGTTCACGGGAAAATAAATCCTGTGGACGACGCGGCAGTTGTAAACATGGAATTGATTT
TCGCGGATTTAGACAGTGCAGACAAACAATTTCAAAGAATTTCAAAAAATGCTAAGAATGGAAACAAAGAAGCACAGGAG
CAGACTTCCGTTCTCGAAAAAATTTTAACCCTTTTAAAGGCAGGAAAACCTGCCAGACTCGCCTCACTAAAAGACGAGGA
AAAAAAGATCGCAAAAAACTTTCAATTGATTACTTTAAAACCGGTTATGTATGTGGCAAACATCGCGGACAAAGACGCTG
CAAAAAAAGATACTCCTTTGCTTACTCAAATCAAACAGATGGCAAAGGAAGAAAACGCCGAACTCGTGATCCTATGCGGT
CGTTTCGAAGAAGAGATTTCCGGTTTGAATCGTAACGAACAACTCGACTTTTTAAAAGAGATCGGAGAAACTGAAAGTGG
TCTAGATCGTATGATTAAAACCGCATATAAACTTCTTGGTTTGATCACGTTTTTTACGGCTGGGGAAATGGAAGTGAGAG
CCTGGACGACTTCATGGAACAGTACCGGACCTAAAGCGGCTTCTGTGATTCATTCCGATTTTGAAAAGGGATTCATCCGG
GCCGAGGTTATGAGCTATGAAGACTTAGACAGGGCCGGAACTCAAACAAAAGTAAAGGAAGAAGGCAAACTTCGAATTGA
AGGAAAAGAATACATAGTACAAGACGGAGATGTCGTTTATTTTCGAATCAACGCCTAG

Upstream 100 bases:

>100_bases
AAGTTTTTCTCTCAACAGTAGTAGCGACGGTTCCGGTAAATCCTGGGAACTGGAGTGATTTTACTTTTCGCTTCGACCTA
TCTCGGAAAATCTGGACTTC

Downstream 100 bases:

>100_bases
AACCCGTCTCAAAACCTTAGAATGTAGGAGCTATTACAATCTTAAACGATGGGAAAAACCTTCAATATGAAGGTTTCTGT
GGGAACTCCCACGTTTTTTA

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MSLNCGIVGLPNVGKSTIFNALTKAGAQMENYPFCTIEPNKGIVEVPDLRLERLAEIAKPQKVVPAIIEFVDIAGLVKGA
SQGEGLGNKFLSHIREVDTICHVVRAFEDENVTHVHGKINPVDDAAVVNMELIFADLDSADKQFQRISKNAKNGNKEAQE
QTSVLEKILTLLKAGKPARLASLKDEEKKIAKNFQLITLKPVMYVANIADKDAAKKDTPLLTQIKQMAKEENAELVILCG
RFEEEISGLNRNEQLDFLKEIGETESGLDRMIKTAYKLLGLITFFTAGEMEVRAWTTSWNSTGPKAASVIHSDFEKGFIR
AEVMSYEDLDRAGTQTKVKEEGKLRIEGKEYIVQDGDVVYFRINA

Sequences:

>Translated_365_residues
MSLNCGIVGLPNVGKSTIFNALTKAGAQMENYPFCTIEPNKGIVEVPDLRLERLAEIAKPQKVVPAIIEFVDIAGLVKGA
SQGEGLGNKFLSHIREVDTICHVVRAFEDENVTHVHGKINPVDDAAVVNMELIFADLDSADKQFQRISKNAKNGNKEAQE
QTSVLEKILTLLKAGKPARLASLKDEEKKIAKNFQLITLKPVMYVANIADKDAAKKDTPLLTQIKQMAKEENAELVILCG
RFEEEISGLNRNEQLDFLKEIGETESGLDRMIKTAYKLLGLITFFTAGEMEVRAWTTSWNSTGPKAASVIHSDFEKGFIR
AEVMSYEDLDRAGTQTKVKEEGKLRIEGKEYIVQDGDVVYFRINA
>Mature_364_residues
SLNCGIVGLPNVGKSTIFNALTKAGAQMENYPFCTIEPNKGIVEVPDLRLERLAEIAKPQKVVPAIIEFVDIAGLVKGAS
QGEGLGNKFLSHIREVDTICHVVRAFEDENVTHVHGKINPVDDAAVVNMELIFADLDSADKQFQRISKNAKNGNKEAQEQ
TSVLEKILTLLKAGKPARLASLKDEEKKIAKNFQLITLKPVMYVANIADKDAAKKDTPLLTQIKQMAKEENAELVILCGR
FEEEISGLNRNEQLDFLKEIGETESGLDRMIKTAYKLLGLITFFTAGEMEVRAWTTSWNSTGPKAASVIHSDFEKGFIRA
EVMSYEDLDRAGTQTKVKEEGKLRIEGKEYIVQDGDVVYFRINA

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=368, Percent_Identity=42.9347826086957, Blast_Score=295, Evalue=3e-80,
Organism=Homo sapiens, GI58761502, Length=217, Percent_Identity=37.3271889400922, Blast_Score=141, Evalue=8e-34,
Organism=Escherichia coli, GI1787454, Length=364, Percent_Identity=51.9230769230769, Blast_Score=394, Evalue=1e-111,
Organism=Escherichia coli, GI1789574, Length=129, Percent_Identity=30.2325581395349, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17509631, Length=367, Percent_Identity=44.4141689373297, Blast_Score=307, Evalue=5e-84,
Organism=Saccharomyces cerevisiae, GI6319499, Length=373, Percent_Identity=41.0187667560322, Blast_Score=262, Evalue=7e-71,
Organism=Saccharomyces cerevisiae, GI6321773, Length=381, Percent_Identity=36.4829396325459, Blast_Score=214, Evalue=1e-56,
Organism=Saccharomyces cerevisiae, GI6321649, Length=343, Percent_Identity=27.6967930029155, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24640873, Length=368, Percent_Identity=42.3913043478261, Blast_Score=294, Evalue=7e-80,
Organism=Drosophila melanogaster, GI24640877, Length=368, Percent_Identity=42.3913043478261, Blast_Score=294, Evalue=7e-80,
Organism=Drosophila melanogaster, GI24640875, Length=368, Percent_Identity=42.3913043478261, Blast_Score=294, Evalue=7e-80,
Organism=Drosophila melanogaster, GI24640879, Length=326, Percent_Identity=39.8773006134969, Blast_Score=236, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24585318, Length=104, Percent_Identity=35.5769230769231, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 40458; Mature: 40327

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNCGIVGLPNVGKSTIFNALTKAGAQMENYPFCTIEPNKGIVEVPDLRLERLAEIAKP
CCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCHHHHHHHHHHCC
QKVVPAIIEFVDIAGLVKGASQGEGLGNKFLSHIREVDTICHVVRAFEDENVTHVHGKIN
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
PVDDAAVVNMELIFADLDSADKQFQRISKNAKNGNKEAQEQTSVLEKILTLLKAGKPARL
CCCCHHEEEEEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHH
ASLKDEEKKIAKNFQLITLKPVMYVANIADKDAAKKDTPLLTQIKQMAKEENAELVILCG
HHCCHHHHHHHCCCEEEEEHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEC
RFEEEISGLNRNEQLDFLKEIGETESGLDRMIKTAYKLLGLITFFTAGEMEVRAWTTSWN
CCHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCC
STGPKAASVIHSDFEKGFIRAEVMSYEDLDRAGTQTKVKEEGKLRIEGKEYIVQDGDVVY
CCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCEECCCCCEEECCCEEEEECCCEEE
FRINA
EEECC
>Mature Secondary Structure 
SLNCGIVGLPNVGKSTIFNALTKAGAQMENYPFCTIEPNKGIVEVPDLRLERLAEIAKP
CCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCHHHHHHHHHHCC
QKVVPAIIEFVDIAGLVKGASQGEGLGNKFLSHIREVDTICHVVRAFEDENVTHVHGKIN
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
PVDDAAVVNMELIFADLDSADKQFQRISKNAKNGNKEAQEQTSVLEKILTLLKAGKPARL
CCCCHHEEEEEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHH
ASLKDEEKKIAKNFQLITLKPVMYVANIADKDAAKKDTPLLTQIKQMAKEENAELVILCG
HHCCHHHHHHHCCCEEEEEHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEC
RFEEEISGLNRNEQLDFLKEIGETESGLDRMIKTAYKLLGLITFFTAGEMEVRAWTTSWN
CCHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCC
STGPKAASVIHSDFEKGFIRAEVMSYEDLDRAGTQTKVKEEGKLRIEGKEYIVQDGDVVY
CCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCEECCCCCEEECCCEEEEECCCEEE
FRINA
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]