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The map label for this gene is kamA [H]

Identifier: 116327784

GI number: 116327784

Start: 1218050

End: 1219312

Strand: Direct

Name: kamA [H]

Synonym: LBL_1044

Alternate gene names: 116327784

Gene position: 1218050-1219312 (Clockwise)

Preceding gene: 116327780

Following gene: 116327785

Centisome position: 33.7

GC content: 44.34

Gene sequence:

>1263_bases
ATGAAGACTTCGAATTCGCATCTGTTCGCACAAAAATCCGAGAAAGAAAGTTTTGCAAATCGGTCTGAGTTGTTTTCTTC
TTTTGATTGGAGCGATTATAAAGCTCAGCTTCAAAATCGTGTGAGAGGTTTCGAGCTGGGGCGTTATTTCGATTTGACGG
AAAGTGAAAAAGTCGGAATTGAGGATACGATTCGTCTCAACGTTTCCGCGACACCATATTACATTTCTCTAACGGACCCG
GAGGACCCGGACGATCCAATTCGAAAGATGATCATCCCGAGAGAAGCGGAGACCGTTTTTTCTCCGGAAGAATCTCCCGA
TCCTCTGCACGAGGAACGATTGTCTCCCGTCAAAGGGTTGACTCACATGTATCCGGATCGAGTTCTTCTTTTTACCAATC
ACGAATGTTCGGTTTATTGTAGACATTGTATGAGAGGTCGTAAGGTCTCCGATTCTAAGGAGAGAATGATTACGGAAGAT
TTGGAAGCTTGCTTTGAATATATTGAAGCATGTCCGGAAATAACCGATGTGGTACTATCCGGCGGAGATCCCCTAAATCT
GAGCGACTCCAAAATCGACCGGATTTTGGAACGATTGGAAAAAATCGAACATGTGAAAATCTGTAGACTCGGTACTCGAA
ATCCGGTCACGCTTCCTTTTCGAATCACATCAGACCTTTGTAATATTATAGAATCTCACAATACCCATCGGCTTTCCATT
TTCTGCAATACCCAATTCAATCACGCGAAAGAATGCACTTCCGAAGCGAAAGAAGCGATTCTAAAACTTCTCAAAGCCGG
AGTGAACGTCGGAAATCAATGTGTTCTACTCAAGGGAATCAACGATTCCGGGGAAATCATGTTAGAACTTCATAAAAAAC
TGTTGGAATTGAGGGTTCGCGCCTATTATATGTATGATCCGGAGCTGATTCCCGGTTCAAGAGGTTTTCGAACCCCGCTC
GCAAAAGGTATCGAAATCATTTCCTATATGAGAGGGAAGATAGGGGGAATGGGAATTCCGCAGTTCGTAAACGATCTTCC
CGGAGGAGGTGGAAAGGTAACGTTGACTCCGGATTGGTATCTTGGTTTTTACAAACCGGAAAGGATGCACGTGTTTCGAT
CCGCGTTACACGGATCCTATCATTTAAGTCCGGAACCTCCGGATTCCACAATGGAAGAAATTTACCCTGAGGTCTCCTTG
GAGACCTGGGAAAGAATTTCTCCGAACGCGTTCGGAGCCAAAGAGAAGAAATTGAATGTATGA

Upstream 100 bases:

>100_bases
GTCATCAAAGGACAACTTTTCGGAAACGAATTCTTTTGACATTTTCTTTTTCCCTTTGCTTGATTTTCCCCGGAGTCGGA
GAAAATAGGAAGAACTTCTT

Downstream 100 bases:

>100_bases
CGTAATGCCGAGCGTTCTTGTTTACGCGGATCTTCACGAGTTTGAAGGGGAGTTTCCGGAAATTTACAAACAGGAATGGG
AATCTTCGAAATCCGTGGAT

Product: lysine 2,3-aminomutase

Products: NA

Alternate protein names: LAM; KAM [H]

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MKTSNSHLFAQKSEKESFANRSELFSSFDWSDYKAQLQNRVRGFELGRYFDLTESEKVGIEDTIRLNVSATPYYISLTDP
EDPDDPIRKMIIPREAETVFSPEESPDPLHEERLSPVKGLTHMYPDRVLLFTNHECSVYCRHCMRGRKVSDSKERMITED
LEACFEYIEACPEITDVVLSGGDPLNLSDSKIDRILERLEKIEHVKICRLGTRNPVTLPFRITSDLCNIIESHNTHRLSI
FCNTQFNHAKECTSEAKEAILKLLKAGVNVGNQCVLLKGINDSGEIMLELHKKLLELRVRAYYMYDPELIPGSRGFRTPL
AKGIEIISYMRGKIGGMGIPQFVNDLPGGGGKVTLTPDWYLGFYKPERMHVFRSALHGSYHLSPEPPDSTMEEIYPEVSL
ETWERISPNAFGAKEKKLNV

Sequences:

>Translated_420_residues
MKTSNSHLFAQKSEKESFANRSELFSSFDWSDYKAQLQNRVRGFELGRYFDLTESEKVGIEDTIRLNVSATPYYISLTDP
EDPDDPIRKMIIPREAETVFSPEESPDPLHEERLSPVKGLTHMYPDRVLLFTNHECSVYCRHCMRGRKVSDSKERMITED
LEACFEYIEACPEITDVVLSGGDPLNLSDSKIDRILERLEKIEHVKICRLGTRNPVTLPFRITSDLCNIIESHNTHRLSI
FCNTQFNHAKECTSEAKEAILKLLKAGVNVGNQCVLLKGINDSGEIMLELHKKLLELRVRAYYMYDPELIPGSRGFRTPL
AKGIEIISYMRGKIGGMGIPQFVNDLPGGGGKVTLTPDWYLGFYKPERMHVFRSALHGSYHLSPEPPDSTMEEIYPEVSL
ETWERISPNAFGAKEKKLNV
>Mature_420_residues
MKTSNSHLFAQKSEKESFANRSELFSSFDWSDYKAQLQNRVRGFELGRYFDLTESEKVGIEDTIRLNVSATPYYISLTDP
EDPDDPIRKMIIPREAETVFSPEESPDPLHEERLSPVKGLTHMYPDRVLLFTNHECSVYCRHCMRGRKVSDSKERMITED
LEACFEYIEACPEITDVVLSGGDPLNLSDSKIDRILERLEKIEHVKICRLGTRNPVTLPFRITSDLCNIIESHNTHRLSI
FCNTQFNHAKECTSEAKEAILKLLKAGVNVGNQCVLLKGINDSGEIMLELHKKLLELRVRAYYMYDPELIPGSRGFRTPL
AKGIEIISYMRGKIGGMGIPQFVNDLPGGGGKVTLTPDWYLGFYKPERMHVFRSALHGSYHLSPEPPDSTMEEIYPEVSL
ETWERISPNAFGAKEKKLNV

Specific function: Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine [H]

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family [H]

Homologues:

Organism=Escherichia coli, GI1790589, Length=282, Percent_Identity=31.5602836879433, Blast_Score=157, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003739
- InterPro:   IPR022459
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: =5.4.3.2 [H]

Molecular weight: Translated: 47900; Mature: 47900

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTSNSHLFAQKSEKESFANRSELFSSFDWSDYKAQLQNRVRGFELGRYFDLTESEKVGI
CCCCCCCEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEECCCEECCCCCCCCCC
EDTIRLNVSATPYYISLTDPEDPDDPIRKMIIPREAETVFSPEESPDPLHEERLSPVKGL
CEEEEEEEECCEEEEEECCCCCCCHHHHHHCCCCCHHHCCCCCCCCCCHHHHHCCHHHHH
THMYPDRVLLFTNHECSVYCRHCMRGRKVSDSKERMITEDLEACFEYIEACPEITDVVLS
HHHCCCEEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHCC
GGDPLNLSDSKIDRILERLEKIEHVKICRLGTRNPVTLPFRITSDLCNIIESHNTHRLSI
CCCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCEEEEEEEHHHHHHHHHCCCCEEEEE
FCNTQFNHAKECTSEAKEAILKLLKAGVNVGNQCVLLKGINDSGEIMLELHKKLLELRVR
EEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHH
AYYMYDPELIPGSRGFRTPLAKGIEIISYMRGKIGGMGIPQFVNDLPGGGGKVTLTPDWY
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEEECCCCE
LGFYKPERMHVFRSALHGSYHLSPEPPDSTMEEIYPEVSLETWERISPNAFGAKEKKLNV
EECCCHHHHHHHHHHHCCCEECCCCCCCHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKTSNSHLFAQKSEKESFANRSELFSSFDWSDYKAQLQNRVRGFELGRYFDLTESEKVGI
CCCCCCCEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEECCCEECCCCCCCCCC
EDTIRLNVSATPYYISLTDPEDPDDPIRKMIIPREAETVFSPEESPDPLHEERLSPVKGL
CEEEEEEEECCEEEEEECCCCCCCHHHHHHCCCCCHHHCCCCCCCCCCHHHHHCCHHHHH
THMYPDRVLLFTNHECSVYCRHCMRGRKVSDSKERMITEDLEACFEYIEACPEITDVVLS
HHHCCCEEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHCC
GGDPLNLSDSKIDRILERLEKIEHVKICRLGTRNPVTLPFRITSDLCNIIESHNTHRLSI
CCCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCEEEEEEEHHHHHHHHHCCCCEEEEE
FCNTQFNHAKECTSEAKEAILKLLKAGVNVGNQCVLLKGINDSGEIMLELHKKLLELRVR
EEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHH
AYYMYDPELIPGSRGFRTPLAKGIEIISYMRGKIGGMGIPQFVNDLPGGGGKVTLTPDWY
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEEECCCCE
LGFYKPERMHVFRSALHGSYHLSPEPPDSTMEEIYPEVSLETWERISPNAFGAKEKKLNV
EECCCHHHHHHHHHHHCCCEECCCCCCCHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10629195 [H]