Click here to switch to the map view.

The map label for this gene is sms [H]

Identifier: 116327595

GI number: 116327595

Start: 957042

End: 958421

Strand: Direct

Name: sms [H]

Synonym: LBL_0827

Alternate gene names: 116327595

Gene position: 957042-958421 (Clockwise)

Preceding gene: 116327594

Following gene: 116327603

Centisome position: 26.48

GC content: 47.25

Gene sequence:

>1380_bases
TTGAAAAAGAGACTTACTCGAACTTTTATTTGCCAGTCCTGTGGTCAGGATTATTCCCGTTGGGCCGGTAAATGCGAGTC
CTGCGGGAATTGGAATTCGATCGTTGAAGAAATCGGCGGTGAGAGATTTGCTCCCTCCGGCGGAAATTCTCGGAAAAATA
AATCGTATCAGGAGCCAATTCCTTTAGACAGAGTAGAGGAAGAATCGCTCGAAAGGATGGGAACCGGTTTGAAAGAACTC
GATCTCGTCTTGGGCGGCGGGCTGGTTCCGGGTTCTCTTACCTTGATTGGCGGGGAGCCCGGCGTCGGAAAATCCACCTT
GGTTCTTGAAGTTTCACGTTATCTGACACAGGCAAATAAAAAGGTTCTTTACATTTCCGGCGAAGAGTCCCCTTCTCAGA
TTCGAATGCGAGCGGAAAGAATGGGATTCCGTTCGTCCAATCTTCTGCTTACCTCCGAGACTTACGCGGAAAATATTTCC
GCAATGATCGAAGGCGCAAGGCCGACGGCGGTTTTTGTGGATTCGATTCAAACAATCGCAAGAGAAGCTCTTCCGAATCA
GGCCGGAACCGTCACCCAACTAAGAGAATGTACTCAAATTTTACTCGAAACCGCCAAACGATCCGGAATTCCGATTTTGA
TGACGGGTCATATTACGAAAGAGGGAACCATTGCGGGTCCGAAAATTTTGGAACATCTTGTGGACACGGTCCTTTATTTC
GAAGGCGATCGACTCAATTATTATCGATTGCTCAGAGCGGTTAAAAATCGTTTTGGTGCCGTGGGGGATCTTGCGATCTT
CGAAATGTTTTCGGGCGGTTTACGAGAAGTAGGGGATCGAAATAGCATTTTTGTCAGTGCAGGTGCGGAGGAAAGAAGCG
GTTCCGTAATCAGCGCAGTGTTGGAAGGTAGTAGAGCTCTCACCGTGGAAGTGCAGGCTTTGGTTAGTAAAACCGGTTTT
GCTCAGGCAAGAAGAATGGCGGAGGGACCGGATACTCGTCGTGTGATTTTGCTTGCTGCAGTGATCGAAAAGTATATCAA
AATCAAATTAGGAGAATGTGATCTATTTAGCAATCTTGCAGGGGGCCTAAATGCGGATGAACCGGCTTTGGATCTTGCGA
TCTGCACTTCGATTATTTCCAGTTATCTCGATCAACCTCTTCCGAAAGGAACTTGCGTTTTGGGCGAGGTCGGTCTTTCG
GGGGAGGTCCGTAGTATCGGTCAAGCCAATCTCCGTATTAAAGAACTTGCAGGGGTCGGTATGAAAAAGGTGATTCTTCC
CGAAGGAAATTTGAGCGAATTGGTCCAAAATACGGACATTCAGATTCAGGGAATTCGTTCTTTGAACGATTTACGTTTGC
TTTTTCCGGGCGTTAATTGA

Upstream 100 bases:

>100_bases
TCGTAAGAGAAGGCAGGGATTCCCTTGCCAGAGAGGCCTTCCGTTGTCTTCCCGTTTTTAATCAGATTGATTGGCTTGAG
ATGCCTTCCCTTTTTGAACA

Downstream 100 bases:

>100_bases
ATTTTTTTGGAAAAGTATTTTAATTTTTTATAATATATTCAGTTTGTTGTTTGCCTCTTAAGGCACGTTGGCTTTTCCAC
ACGTGGGATCGGTGTTGTAA

Product: DNA repair protein RadA

Products: NA

Alternate protein names: DNA repair protein sms homolog [H]

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MKKRLTRTFICQSCGQDYSRWAGKCESCGNWNSIVEEIGGERFAPSGGNSRKNKSYQEPIPLDRVEEESLERMGTGLKEL
DLVLGGGLVPGSLTLIGGEPGVGKSTLVLEVSRYLTQANKKVLYISGEESPSQIRMRAERMGFRSSNLLLTSETYAENIS
AMIEGARPTAVFVDSIQTIAREALPNQAGTVTQLRECTQILLETAKRSGIPILMTGHITKEGTIAGPKILEHLVDTVLYF
EGDRLNYYRLLRAVKNRFGAVGDLAIFEMFSGGLREVGDRNSIFVSAGAEERSGSVISAVLEGSRALTVEVQALVSKTGF
AQARRMAEGPDTRRVILLAAVIEKYIKIKLGECDLFSNLAGGLNADEPALDLAICTSIISSYLDQPLPKGTCVLGEVGLS
GEVRSIGQANLRIKELAGVGMKKVILPEGNLSELVQNTDIQIQGIRSLNDLRLLFPGVN

Sequences:

>Translated_459_residues
MKKRLTRTFICQSCGQDYSRWAGKCESCGNWNSIVEEIGGERFAPSGGNSRKNKSYQEPIPLDRVEEESLERMGTGLKEL
DLVLGGGLVPGSLTLIGGEPGVGKSTLVLEVSRYLTQANKKVLYISGEESPSQIRMRAERMGFRSSNLLLTSETYAENIS
AMIEGARPTAVFVDSIQTIAREALPNQAGTVTQLRECTQILLETAKRSGIPILMTGHITKEGTIAGPKILEHLVDTVLYF
EGDRLNYYRLLRAVKNRFGAVGDLAIFEMFSGGLREVGDRNSIFVSAGAEERSGSVISAVLEGSRALTVEVQALVSKTGF
AQARRMAEGPDTRRVILLAAVIEKYIKIKLGECDLFSNLAGGLNADEPALDLAICTSIISSYLDQPLPKGTCVLGEVGLS
GEVRSIGQANLRIKELAGVGMKKVILPEGNLSELVQNTDIQIQGIRSLNDLRLLFPGVN
>Mature_459_residues
MKKRLTRTFICQSCGQDYSRWAGKCESCGNWNSIVEEIGGERFAPSGGNSRKNKSYQEPIPLDRVEEESLERMGTGLKEL
DLVLGGGLVPGSLTLIGGEPGVGKSTLVLEVSRYLTQANKKVLYISGEESPSQIRMRAERMGFRSSNLLLTSETYAENIS
AMIEGARPTAVFVDSIQTIAREALPNQAGTVTQLRECTQILLETAKRSGIPILMTGHITKEGTIAGPKILEHLVDTVLYF
EGDRLNYYRLLRAVKNRFGAVGDLAIFEMFSGGLREVGDRNSIFVSAGAEERSGSVISAVLEGSRALTVEVQALVSKTGF
AQARRMAEGPDTRRVILLAAVIEKYIKIKLGECDLFSNLAGGLNADEPALDLAICTSIISSYLDQPLPKGTCVLGEVGLS
GEVRSIGQANLRIKELAGVGMKKVILPEGNLSELVQNTDIQIQGIRSLNDLRLLFPGVN

Specific function: May play a role in the repair of endogenous alkylation damage [H]

COG id: COG1066

COG function: function code O; Predicted ATP-dependent serine protease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recA family. RadA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790850, Length=463, Percent_Identity=41.2526997840173, Blast_Score=355, Evalue=4e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014774
- InterPro:   IPR004504
- InterPro:   IPR008269
- InterPro:   IPR020568 [H]

Pfam domain/function: PF06745 KaiC; PF05362 Lon_C [H]

EC number: NA

Molecular weight: Translated: 49728; Mature: 49728

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS50162 RECA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRLTRTFICQSCGQDYSRWAGKCESCGNWNSIVEEIGGERFAPSGGNSRKNKSYQEPI
CCCHHHHHHHHHHHCHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
PLDRVEEESLERMGTGLKELDLVLGGGLVPGSLTLIGGEPGVGKSTLVLEVSRYLTQANK
CCCCCCHHHHHHHCCCHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCC
KVLYISGEESPSQIRMRAERMGFRSSNLLLTSETYAENISAMIEGARPTAVFVDSIQTIA
EEEEEECCCCHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHCCCCCHHHHHHHHHHHH
REALPNQAGTVTQLRECTQILLETAKRSGIPILMTGHITKEGTIAGPKILEHLVDTVLYF
HHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHC
EGDRLNYYRLLRAVKNRFGAVGDLAIFEMFSGGLREVGDRNSIFVSAGAEERSGSVISAV
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHCCCCCCEEEECCCCCCCCHHHHHH
LEGSRALTVEVQALVSKTGFAQARRMAEGPDTRRVILLAAVIEKYIKIKLGECDLFSNLA
HCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEECCCCHHHHHHC
GGLNADEPALDLAICTSIISSYLDQPLPKGTCVLGEVGLSGEVRSIGQANLRIKELAGVG
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHCCCCCCCHHHHHCCC
MKKVILPEGNLSELVQNTDIQIQGIRSLNDLRLLFPGVN
CEEEEECCCCHHHHHCCCCEEEEECCCCCCEEEECCCCC
>Mature Secondary Structure
MKKRLTRTFICQSCGQDYSRWAGKCESCGNWNSIVEEIGGERFAPSGGNSRKNKSYQEPI
CCCHHHHHHHHHHHCHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
PLDRVEEESLERMGTGLKELDLVLGGGLVPGSLTLIGGEPGVGKSTLVLEVSRYLTQANK
CCCCCCHHHHHHHCCCHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCC
KVLYISGEESPSQIRMRAERMGFRSSNLLLTSETYAENISAMIEGARPTAVFVDSIQTIA
EEEEEECCCCHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHCCCCCHHHHHHHHHHHH
REALPNQAGTVTQLRECTQILLETAKRSGIPILMTGHITKEGTIAGPKILEHLVDTVLYF
HHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHC
EGDRLNYYRLLRAVKNRFGAVGDLAIFEMFSGGLREVGDRNSIFVSAGAEERSGSVISAV
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHCCCCCCEEEECCCCCCCCHHHHHH
LEGSRALTVEVQALVSKTGFAQARRMAEGPDTRRVILLAAVIEKYIKIKLGECDLFSNLA
HCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEECCCCHHHHHHC
GGLNADEPALDLAICTSIISSYLDQPLPKGTCVLGEVGLSGEVRSIGQANLRIKELAGVG
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHCCCCCCCHHHHHCCC
MKKVILPEGNLSELVQNTDIQIQGIRSLNDLRLLFPGVN
CEEEEECCCCHHHHHCCCCEEEEECCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 8016066 [H]