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The map label for this gene is yfbQ [C]

Identifier: 116327583

GI number: 116327583

Start: 940918

End: 942222

Strand: Direct

Name: yfbQ [C]

Synonym: LBL_0814

Alternate gene names: 116327583

Gene position: 940918-942222 (Clockwise)

Preceding gene: 116327582

Following gene: 116327584

Centisome position: 26.03

GC content: 44.9

Gene sequence:

>1305_bases
ATGAGAAGAAACATCGTTCACAGCGGAGCGGACGCTCTGATCTATGAAATCAGACAGATTGCAGCCGTCGCAAAAAAGCT
GGAGGCTTTGGGTCTACAGATCACTTATGAAAATATAGGGGATCCGATTCTCAAAGGAGAATCCATCCCTGATTGGATGA
AAGAAATCGTATCCGATCTTGTGATGAAAGATAAGTCTTGGGCCTATACCGCCACACAAGGTTACGAGCCTACCCGTGAA
TTTCTCGCCCGAAAAGTGAACGAAAGAGGAGGAGCACAGATCACAGCGGACGATCTTCTATTTTTCAACGGATTGGGAGA
CGCGGTCGCAAAAATATTCGGTTTTATGCGAAGGGAAGCCCGAGTTTTAGGACCAAGTCCCGCGTATTCCACTATCTCTT
CCGCCGAGGCGGCGCATAGCGGGTATGAACACTTAACGTATAATCTTCTACCGGAACATAATTGGATGCCGGATTTGGAG
GATATGGAAAACAAAGTGCGTTATAACGATTCCATAGCGGGAATTTTACTCATAAATCCGGACAACCCTACCGGTGCAGT
ATATGACAAAGTTCTTATGAAGCAGATCGTATCAATCTGTGAAAAATACGATCTTATGTTGATTTGCGACGAGACATACG
CACACGTGAACTATTCCGATCATGGGCCTCTTCATCTTTCGGAAGTCATAGGAGACAAGGTGCCGGGAATGGCGCTGCGA
TCCATTTCAAAAGAGTTTCCTTGGCCGGGGGGACGTTGCGGATGGCTTGAGATCTTTAACAAAGAAAAGGATCCTGTTTT
TAGCCGTTACATAAAATCGTTGTTAGACGCAAAAATGCTCGAAGTATGTTCGACCACGCTGCCTCAGATGGCGATACCCG
AAGTATATTCTCATCCGGAATTTATTCCGCACTTAAAAAGAAGAAACGAAAAGTTCAAAAAACGCGCACATATTGCAACG
GAATACTTTTCCGGGCTAAAAGGTGTAAAGGTGGTGGAGCCTAAGGGGGCGTTTTATCTTACGGTTGCTTTTGACGACAA
TGTTTTAAATTCTTCCATGAGGTTGAATGTGGAGAACAAAAAAGCCGAAGAGTTCATCCAGCCGCTTTTGACGTCCGCCG
CAAACGACAGAAGATTTGTGTACTATTTATTGGCTTCCACGGGAATTTGTGTCGTGCCCTTATCCGCGTTTTGTACGTTA
AAAGAAGGATTTCGCGTAACGTTACTCGAAGAAAGCGAAGAAAAATTCGATTGGATCTACAGGACGCTTCGAGATAGAAT
CGGCGAATATATCGCTTCCGTCTAA

Upstream 100 bases:

>100_bases
CTCAAGCTCCGTATCTATCGGGAAAAATCGACGCTGGAACTTCCGGTGAAGTTGATTCAAAAATAACGAGTTGGAATTTT
AAGGAAAAAAAGAGAGCGGT

Downstream 100 bases:

>100_bases
AATTAGTTTCGATTGAGAGTTTACAATTGAAAGGGCCGCTAAAGATCGGATTGATGGATTCCGGAATGGGCGGTTTGTCG
GTACTTAAGGGAATTCTGAA

Product: aminotransferase

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MRRNIVHSGADALIYEIRQIAAVAKKLEALGLQITYENIGDPILKGESIPDWMKEIVSDLVMKDKSWAYTATQGYEPTRE
FLARKVNERGGAQITADDLLFFNGLGDAVAKIFGFMRREARVLGPSPAYSTISSAEAAHSGYEHLTYNLLPEHNWMPDLE
DMENKVRYNDSIAGILLINPDNPTGAVYDKVLMKQIVSICEKYDLMLICDETYAHVNYSDHGPLHLSEVIGDKVPGMALR
SISKEFPWPGGRCGWLEIFNKEKDPVFSRYIKSLLDAKMLEVCSTTLPQMAIPEVYSHPEFIPHLKRRNEKFKKRAHIAT
EYFSGLKGVKVVEPKGAFYLTVAFDDNVLNSSMRLNVENKKAEEFIQPLLTSAANDRRFVYYLLASTGICVVPLSAFCTL
KEGFRVTLLEESEEKFDWIYRTLRDRIGEYIASV

Sequences:

>Translated_434_residues
MRRNIVHSGADALIYEIRQIAAVAKKLEALGLQITYENIGDPILKGESIPDWMKEIVSDLVMKDKSWAYTATQGYEPTRE
FLARKVNERGGAQITADDLLFFNGLGDAVAKIFGFMRREARVLGPSPAYSTISSAEAAHSGYEHLTYNLLPEHNWMPDLE
DMENKVRYNDSIAGILLINPDNPTGAVYDKVLMKQIVSICEKYDLMLICDETYAHVNYSDHGPLHLSEVIGDKVPGMALR
SISKEFPWPGGRCGWLEIFNKEKDPVFSRYIKSLLDAKMLEVCSTTLPQMAIPEVYSHPEFIPHLKRRNEKFKKRAHIAT
EYFSGLKGVKVVEPKGAFYLTVAFDDNVLNSSMRLNVENKKAEEFIQPLLTSAANDRRFVYYLLASTGICVVPLSAFCTL
KEGFRVTLLEESEEKFDWIYRTLRDRIGEYIASV
>Mature_434_residues
MRRNIVHSGADALIYEIRQIAAVAKKLEALGLQITYENIGDPILKGESIPDWMKEIVSDLVMKDKSWAYTATQGYEPTRE
FLARKVNERGGAQITADDLLFFNGLGDAVAKIFGFMRREARVLGPSPAYSTISSAEAAHSGYEHLTYNLLPEHNWMPDLE
DMENKVRYNDSIAGILLINPDNPTGAVYDKVLMKQIVSICEKYDLMLICDETYAHVNYSDHGPLHLSEVIGDKVPGMALR
SISKEFPWPGGRCGWLEIFNKEKDPVFSRYIKSLLDAKMLEVCSTTLPQMAIPEVYSHPEFIPHLKRRNEKFKKRAHIAT
EYFSGLKGVKVVEPKGAFYLTVAFDDNVLNSSMRLNVENKKAEEFIQPLLTSAANDRRFVYYLLASTGICVVPLSAFCTL
KEGFRVTLLEESEEKFDWIYRTLRDRIGEYIASV

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=367, Percent_Identity=24.5231607629428, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI19263340, Length=387, Percent_Identity=24.5478036175711, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI215599424, Length=387, Percent_Identity=24.5478036175711, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI4885351, Length=367, Percent_Identity=25.0681198910082, Blast_Score=73, Evalue=6e-13,
Organism=Escherichia coli, GI1788627, Length=346, Percent_Identity=26.5895953757225, Blast_Score=121, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI71981209, Length=388, Percent_Identity=26.0309278350515, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17567663, Length=311, Percent_Identity=26.0450160771704, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320317, Length=363, Percent_Identity=27.8236914600551, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6323118, Length=357, Percent_Identity=27.7310924369748, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI18859735, Length=314, Percent_Identity=26.7515923566879, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI45551451, Length=376, Percent_Identity=25, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24641770, Length=376, Percent_Identity=25, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24641760, Length=376, Percent_Identity=25, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24641768, Length=376, Percent_Identity=25, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24641766, Length=376, Percent_Identity=25, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24641764, Length=376, Percent_Identity=25, Blast_Score=79, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 49188; Mature: 49188

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRNIVHSGADALIYEIRQIAAVAKKLEALGLQITYENIGDPILKGESIPDWMKEIVSDL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEHHHCCCCHHCCCCCHHHHHHHHHHH
VMKDKSWAYTATQGYEPTREFLARKVNERGGAQITADDLLFFNGLGDAVAKIFGFMRREA
HHCCCCCEEEECCCCCHHHHHHHHHHHHCCCCEEEHHHHHEECCHHHHHHHHHHHHHHHH
RVLGPSPAYSTISSAEAAHSGYEHLTYNLLPEHNWMPDLEDMENKVRYNDSIAGILLINP
HHCCCCCCHHHHHHHHHHHCCHHHEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEEECC
DNPTGAVYDKVLMKQIVSICEKYDLMLICDETYAHVNYSDHGPLHLSEVIGDKVPGMALR
CCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCEEEECCCCCCCEEHHHHHCCCCCCHHHH
SISKEFPWPGGRCGWLEIFNKEKDPVFSRYIKSLLDAKMLEVCSTTLPQMAIPEVYSHPE
HHHHHCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHCHHHHCCCH
FIPHLKRRNEKFKKRAHIATEYFSGLKGVKVVEPKGAFYLTVAFDDNVLNSSMRLNVENK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEEEEECCCHHCCCEEEEECHH
KAEEFIQPLLTSAANDRRFVYYLLASTGICVVPLSAFCTLKEGFRVTLLEESEEKFDWIY
HHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEHHHHHHHCCCCEEEEECCCHHHHHHHH
RTLRDRIGEYIASV
HHHHHHHHHHHHCC
>Mature Secondary Structure
MRRNIVHSGADALIYEIRQIAAVAKKLEALGLQITYENIGDPILKGESIPDWMKEIVSDL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEHHHCCCCHHCCCCCHHHHHHHHHHH
VMKDKSWAYTATQGYEPTREFLARKVNERGGAQITADDLLFFNGLGDAVAKIFGFMRREA
HHCCCCCEEEECCCCCHHHHHHHHHHHHCCCCEEEHHHHHEECCHHHHHHHHHHHHHHHH
RVLGPSPAYSTISSAEAAHSGYEHLTYNLLPEHNWMPDLEDMENKVRYNDSIAGILLINP
HHCCCCCCHHHHHHHHHHHCCHHHEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEEECC
DNPTGAVYDKVLMKQIVSICEKYDLMLICDETYAHVNYSDHGPLHLSEVIGDKVPGMALR
CCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCEEEECCCCCCCEEHHHHHCCCCCCHHHH
SISKEFPWPGGRCGWLEIFNKEKDPVFSRYIKSLLDAKMLEVCSTTLPQMAIPEVYSHPE
HHHHHCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHCHHHHCCCH
FIPHLKRRNEKFKKRAHIATEYFSGLKGVKVVEPKGAFYLTVAFDDNVLNSSMRLNVENK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEEEEECCCHHCCCEEEEECHH
KAEEFIQPLLTSAANDRRFVYYLLASTGICVVPLSAFCTLKEGFRVTLLEESEEKFDWIY
HHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEHHHHHHHCCCCEEEEECCCHHHHHHHH
RTLRDRIGEYIASV
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]